4-hydroxyproline (BioDeep_00000269144)

Main id: BioDeep_00000000265

Secondary id: BioDeep_00000000731, BioDeep_00000015563, BioDeep_00000229679

PANOMIX_OTCML-2023


代谢物信息卡片


cis-4-Hydroxy-L-proline

化学式: C5H9NO3 (131.0582404)
中文名称: L-羟基脯氨酸, 顺式-4-羟基-L-脯氨酸, 顺式-4-羟基-L-脯氨酸, L-羟基脯氨酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.44%

分子结构信息

SMILES: C1C(CNC1C(=O)O)O
InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)

描述信息

A monohydroxyproline where the hydroxy group is located at the 4-position. It is found in fibrillar collagen.
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; PMMYEEVYMWASQN_STSL_0115_4-Hydroxyproline_8000fmol_180430_S2_LC02_MS02_67; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors[1][2][3][4].
cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors[1][2][3][4].
L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

同义名列表

4 个代谢物同义名

4-hydroxyproline; L-Hydroxyproline; cis-4-Hydroxy-L-proline; L-Hydroxyproline,BioReagent, suitable for cell culture



数据库引用编号

65 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Kyohei Takano, Marisa Kaneda, Yayoi Aoki, Nina Fujita, Shigeki Chiba, Seiwa Michihara, Li-Kun Han, Ryuji Takahashi. The protective effects of Ninjin'yoeito against liver steatosis/fibrosis in a non-alcoholic steatohepatitis model mouse. Journal of natural medicines. 2024 Jun; 78(3):514-524. doi: 10.1007/s11418-024-01786-2. [PMID: 38498120]
  • Manar M Abu-Nawareg, Hanan K Abouelseoud, Ahmed Z Zidan. Effect of Salvadora persica on resin-dentin bond stability. BMC oral health. 2024 Apr; 24(1):505. doi: 10.1186/s12903-024-04244-3. [PMID: 38684974]
  • Nimra Riasat, Muniba Jadoon, Nosheen Akhtar, Marya Nawaz Kiani, Humaira Fatima, Mostafa A Abdel-Maksoud, Syeda Masooma Ali, Akram A Alfuraydi, M Junaid Dar, Ihsan Ul Haq. Polyphenolic characterization and biological assessment of Acacia nilotica (L.) wild. Ex delilie: An In vitro and In vivo appraisal of wound healing potential. Journal of ethnopharmacology. 2024 Feb; ?(?):117842. doi: 10.1016/j.jep.2024.117842. [PMID: 38310987]
  • Esra Kupeli Akkol, Muberra Kosar, Ayse Baldemir, Gökçe Şeker Karatoprak, Eren Demirpolat, Mukerrem Betul Yerer Aycan, Ipek Suntar, Selen Ilgun. THE WOUND HEALING POTENTIAL OF THE ENDEMIC PLANT  HELIANTHEMUM CANUM (L.) BAUMG: PRECLINICAL STUDIES SUPPORTED WITH PHYTOCHEMICAL PROFILING. Chemistry & biodiversity. 2023 Nov; ?(?):e202301529. doi: 10.1002/cbdv.202301529. [PMID: 37955210]
  • Shanshan Wang, Fei Ye, Qingjia Ren, Shengnan Sun, Weina Xia, Zhuwei Wang, Haolin Guo, Han Li, Shujing Zhang, Scott Lowe, Meng Chen, Qinghong Du, Weihong Li. The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro. Journal of ethnopharmacology. 2023 Oct; ?(?):117283. doi: 10.1016/j.jep.2023.117283. [PMID: 37827298]
  • Nicole Canon, Catherine H Schein, Werner Braun, Surendra S Negi, Xueni Chen, Michael D Kulis, Edwin H Kim, Vidya Pathy, Marina Pozzoli, Weimin Liu, Stephen C Dreskin. Alanine Scanning of the Unstructured Region of Ara h 2 and of a Related Mimotope Reveals Critical Amino Acids for IgE Binding. Molecular nutrition & food research. 2023 Sep; ?(?):e2300134. doi: 10.1002/mnfr.202300134. [PMID: 37706599]
  • Uddhab Karki, Paula Perez Sanchez, Sankalpa Chakraborty, Berry Dickey, Jacqueline Vargas Ulloa, Ningning Zhang, Jianfeng Xu. Intracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis. Scientific reports. 2023 08; 13(1):13506. doi: 10.1038/s41598-023-40723-3. [PMID: 37598266]
  • Yang Liu, Amei Tang, Ming Liu, Changjun Xu, Feng Cao, Changfu Yang. Tuberostemonine may enhance the function of the SLC7A11/glutamate antiporter to restrain the ferroptosis to alleviate pulmonary fibrosis. Journal of ethnopharmacology. 2023 Aug; 318(Pt B):116983. doi: 10.1016/j.jep.2023.116983. [PMID: 37532076]
  • Xiaojia He, Zachery R Jarrell, Matthew Ryan Smith, ViLinh Thi Ly, Xin Hu, Viranuj Sueblinvong, Yongliang Liang, Michael Orr, Young-Mi Go, Dean P Jones. Low-dose vanadium pentoxide perturbed lung metabolism associated with inflammation and fibrosis signaling in male animal and in vitro models. American journal of physiology. Lung cellular and molecular physiology. 2023 Jun; ?(?):. doi: 10.1152/ajplung.00303.2022. [PMID: 37310758]
  • Bo Bao, Jinpeng Liu, Tuling Li, Zhaohui Yang, Guimin Wang, Jizhao Xin, Hongsheng Bi, Dadong Guo. Elevated retinal fibrosis in experimental myopia is involved in the activation of the PI3K/AKT/ERK signaling pathway. Archives of biochemistry and biophysics. 2023 Jun; 743(?):109663. doi: 10.1016/j.abb.2023.109663. [PMID: 37290701]
  • Syeda Roop Fatima Jaffri, Holly Scheer, Cora A MacAlister. The hydroxyproline O-arabinosyltransferase FIN4 is required for tomato pollen intine development. Plant reproduction. 2023 06; 36(2):173-191. doi: 10.1007/s00497-023-00459-6. [PMID: 36749417]
  • Jasper W van de Sande, Bauke Albada. Chemical Synthesis of Glycopeptides containing l-Arabinosylated Hydroxyproline and Sulfated Tyrosine. Organic letters. 2023 03; 25(11):1907-1911. doi: 10.1021/acs.orglett.3c00411. [PMID: 36917069]
  • Usama W Hawas, Mohamed A El-Ansari, Abeer F Osman, Asmaa F Galal, Lamia T Abou El-Kassem. Flavonoid constituents and protective efficacy of Citrus reticulate (Blanco) leaves ethanolic extract on thioacetamide-induced liver injury rats. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2023 Mar; 28(2):160-167. doi: 10.1080/1354750x.2022.2151645. [PMID: 36420657]
  • Alankar Shrivastav, Arun Kumar Mishra, Asheessh Kumar Gupta. Evaluation of Wound Healing Potential of Root Bark Extract of Berberis Aristata and Molecular Docking Analysis of Berberis Phytoconstituents. Current drug discovery technologies. 2023 Feb; ?(?):. doi: 10.2174/1570163820666230221154851. [PMID: 36824006]
  • Diana Moreira, Dasmeet Kaur, Ana Marta Pereira, Michael A Held, Allan M Showalter, Sílvia Coimbra. Type II arabinogalactans initiated by hydroxyproline-O-galactosyltransferases play important roles in pollen - pistil interactions. The Plant journal : for cell and molecular biology. 2023 Feb; ?(?):. doi: 10.1111/tpj.16141. [PMID: 36775989]
  • Ashkan Karbasi, Anahita Abbasifard, Farzin Firouzian, Sara Soleimani Asl, Zahra Azizi, Akram Ranjbar. Is nanoparaquat safer than bulk paraquat? An in vitro and in vivo evaluation. Toxicology. 2023 01; 484(?):153398. doi: 10.1016/j.tox.2022.153398. [PMID: 36535436]
  • Akihiro Ishiwata, Hanako Tsunomachi, Kyohei Kameyama, Kaeothip Sophon, Masayuki Nakamura, Kanefumi Kitahara, Katsunori Tanaka, Yukishige Ito, Kiyotaka Fujita. Bifidobacterial GH146 β-l-Arabinofuranosidase (Bll4HypBA1) as the Last Enzyme for the Complete Removal of Oligoarabinofuranosides from Hydroxyproline-Rich Glycoproteins. Chembiochem : a European journal of chemical biology. 2022 Dec; ?(?):e202200637. doi: 10.1002/cbic.202200637. [PMID: 36579407]
  • Monika Kopečná, Miloslav Macháček, Jaroslav Roh, Kateřina Vávrová. Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversible transdermal permeation enhancers. Scientific reports. 2022 11; 12(1):19495. doi: 10.1038/s41598-022-24108-6. [PMID: 36376455]
  • Ahmad Za'al Alsarayreh, Sawsan Attalah Oran, Jumah Mutie Shakhanbeh. In vitro and in vivo wound healing activities of Globularia arabica leaf methanolic extract in diabetic rats. Journal of cosmetic dermatology. 2022 Oct; 21(10):4888-4900. doi: 10.1111/jocd.14882. [PMID: 35212131]
  • Xueyan Zhang, Ruijie Wang, Jian Lv, Qing Sun. Q-Switched 1064 nm Nd:YAG Laser Rejuvenates Photoaging Skin of Rats by Downregulating miR-196b-5p. Photobiomodulation, photomedicine, and laser surgery. 2022 Oct; 40(10):708-714. doi: 10.1089/photob.2022.0036. [PMID: 36286575]
  • Puneet Gupta, Ashish Singh, Neelam Singh, Faraat Ali, Ayushi Tyagi, Sadish K Shanmugam. Healing Potential of Propolis Extract-Passiflora edulis Seed Oil Emulgel Against Excisional Wound: Biochemical, Histopathological, and Cytokines Level Evidence. Assay and drug development technologies. 2022 10; 20(7):300-316. doi: 10.1089/adt.2022.075. [PMID: 36269233]
  • Heather G Marco, Simone König, Gerd Gäde. Mass Spectrometric Proof of Predicted Peptides: Novel Adipokinetic Hormones in Insects. Molecules (Basel, Switzerland). 2022 Oct; 27(19):. doi: 10.3390/molecules27196469. [PMID: 36235010]
  • Amir Siahpoosh, Alireza Malayeri, Anayatollah Salimi, Layasadat Khorsandi, Zeinab Zaheri Abdevand. Determination of the effectiveness of Dorema ammoniacum gum on wound healing: an experimental study. Journal of wound care. 2022 Oct; 31(Sup10):S16-S27. doi: 10.12968/jowc.2022.31.sup10.s16. [PMID: 36240871]
  • Parveen Kumar, Zhengqin Yang, Jeremie M Lever, Miranda D Chávez, Huma Fatima, David K Crossman, Craig L Maynard, James F George, Tanecia Mitchell. Hydroxyproline stimulates inflammation and reprograms macrophage signaling in a rat kidney stone model. Biochimica et biophysica acta. Molecular basis of disease. 2022 09; 1868(9):166442. doi: 10.1016/j.bbadis.2022.166442. [PMID: 35562038]
  • Ahmad Za'al Alsarayreh, Sawsan Atallah Oran, Jumah Mutie Shakhanbeh. Effect of Rhus coriaria L. methanolic fruit extract on wound healing in diabetic and non-diabetic rats. Journal of cosmetic dermatology. 2022 Aug; 21(8):3567-3577. doi: 10.1111/jocd.14668. [PMID: 34928525]
  • Cecilia M Lara-Mondragón, Alexandria Dorchak, Cora A MacAlister. O-glycosylation of the extracellular domain of pollen class I formins modulates their plasma membrane mobility. Journal of experimental botany. 2022 06; 73(12):3929-3945. doi: 10.1093/jxb/erac131. [PMID: 35383367]
  • Huahong Yang, Lidong Wang, Manshi Yang, Jianqiang Hu, Erli Zhang, Liping Peng. Oridonin attenuates LPS-induced early pulmonary fibrosis by regulating impaired autophagy, oxidative stress, inflammation and EMT. European journal of pharmacology. 2022 May; 923(?):174931. doi: 10.1016/j.ejphar.2022.174931. [PMID: 35398392]
  • Yanfeng Li, Miaomiao Li, Rui Wang, Biyu Wang, Seyyed Shamsadin Athari, Jinli Wang. Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects. Respiratory physiology & neurobiology. 2022 05; 299(?):103843. doi: 10.1016/j.resp.2022.103843. [PMID: 35026480]
  • Shengdi Hu, Wenliang He, Guoyao Wu. Hydroxyproline in animal metabolism, nutrition, and cell signaling. Amino acids. 2022 Apr; 54(4):513-528. doi: 10.1007/s00726-021-03056-x. [PMID: 34342708]
  • Lin Han, Yanfang Zou, Chen Yu. Targeting CC chemokine ligand (CCL) 20 by miR-143-5p alleviate lead poisoning-induced renal fibrosis by regulating interstitial fibroblasts excessive proliferation and dysfunction. Bioengineered. 2022 04; 13(4):11156-11168. doi: 10.1080/21655979.2022.2062106. [PMID: 35485286]
  • Chan Jung Liu, Yau Sheng Tsai, Ho Shiang Huang. Atorvastatin Decreases Renal Calcium Oxalate Stone Deposits by Enhancing Renal Osteopontin Expression in Hyperoxaluric Stone-Forming Rats Fed a High-Fat Diet. International journal of molecular sciences. 2022 Mar; 23(6):. doi: 10.3390/ijms23063048. [PMID: 35328466]
  • Sebastian Kwiatkowski, Maria Bozko, Michal Zarod, Apolonia Witecka, Kubra Kocdemir, Adam K Jagielski, Jakub Drozak. Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104). The Journal of biological chemistry. 2022 03; 298(3):101708. doi: 10.1016/j.jbc.2022.101708. [PMID: 35150746]
  • Hussan Omar, Feng Gao, Hyemin Yoo, Odair Bim, Carolina Garcia, Kathy J LePard, John C Mitchell, Gina Agostini-Walesch, Marcela R Carrilho. Changes to dentin extracellular matrix following treatment with plant-based polyphenols. Journal of the mechanical behavior of biomedical materials. 2022 02; 126(?):105055. doi: 10.1016/j.jmbbm.2021.105055. [PMID: 34929591]
  • Yu Iwasaki, Mizuho Nakatogawa, Ayaka Shimizu, Yoshio Sato, Yasutaka Shigemura. Comparison of gelatin and low-molecular weight gelatin hydrolysate ingestion on hydroxyproline (Hyp), Pro-Hyp and Hyp-Gly concentrations in human blood. Food chemistry. 2022 Feb; 369(?):130869. doi: 10.1016/j.foodchem.2021.130869. [PMID: 34461513]
  • Ruth Belostotsky, Yaacov Frishberg. Catabolism of Hydroxyproline in Vertebrates: Physiology, Evolution, Genetic Diseases and New siRNA Approach for Treatment. International journal of molecular sciences. 2022 Jan; 23(2):. doi: 10.3390/ijms23021005. [PMID: 35055190]
  • Xin Xue, Ji-Bo Kang, Xiao Yang, Nan Li, Liang Chang, Juan Ji, Xiang-Kai Meng, Hai-Qing Zhang, Yue Zhong, Shao-Peng Yu, Wen-Yu Wu, Xiao-Long Wang, Nian-Guang Li, Shan-Liang Sun. An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL. European journal of medicinal chemistry. 2022 Jan; 227(?):113871. doi: 10.1016/j.ejmech.2021.113871. [PMID: 34638033]
  • Shaymaa Fadhel Abbas Albaayit, Rasedee Abdullah, Mohd Hezmee Mohd Noor. Zerumbone-Loaded Nanostructured Lipid Carrier Gel Enhances Wound Healing in Diabetic Rats. BioMed research international. 2022; 2022(?):1129297. doi: 10.1155/2022/1129297. [PMID: 36124067]
  • Dasmeet Kaur, Michael A Held, Mountain R Smith, Allan M Showalter. Functional characterization of hydroxyproline-O-galactosyltransferases for Arabidopsis arabinogalactan-protein synthesis. BMC plant biology. 2021 Dec; 21(1):590. doi: 10.1186/s12870-021-03362-2. [PMID: 34903166]
  • Bo Lu, Jun Xie, Deyu Fu, Xiaozhe Chen, Mingyi Zhao, Mingtai Gui, Lei Yao, Xunjie Zhou, Jianhua Li. Huoxue Qianyang Qutan recipe attenuates cardiac fibrosis by inhibiting the NLRP3 inflammasome signalling pathway in obese hypertensive rats. Pharmaceutical biology. 2021 Dec; 59(1):1045-1057. doi: 10.1080/13880209.2021.1953541. [PMID: 34362291]
  • Fatemeh Kalantari, Ali Ramazani, Mohammad Reza Poor Heravi, Hamideh Aghahosseini, Katarzyna Ślepokura. Magnetic Nanoparticles Functionalized with Copper Hydroxyproline Complexes as an Efficient, Recoverable, and Recyclable Nanocatalyst: Synthesis and Its Catalytic Application in a Tandem Knoevenagel-Michael Cyclocondensation Reaction. Inorganic chemistry. 2021 Oct; 60(19):15010-15023. doi: 10.1021/acs.inorgchem.1c02470. [PMID: 34533947]
  • Debabrata Dutta, Shakilur Rahman, Gourab Bhattacharje, Swarnendu Bag, Bidhan Chandra Sing, Jyotirmoy Chatterjee, Amit Basak, Amit Kumar Das. Label-Free Method Development for Hydroxyproline PTM Mapping in Human Plasma Proteome. The protein journal. 2021 10; 40(5):741-755. doi: 10.1007/s10930-021-09984-7. [PMID: 33840009]
  • Meike Hasenzahl, Mathias Müsken, Sonja Mertsch, Stefan Schrader, Stephan Reichl. Cell sheet technology: Influence of culture conditions on in vitro-cultivated corneal stromal tissue for regenerative therapies of the ocular surface. Journal of biomedical materials research. Part B, Applied biomaterials. 2021 10; 109(10):1488-1504. doi: 10.1002/jbm.b.34808. [PMID: 33538123]
  • Chidozie I Onwuka, Chibuzo C Uguru, Chidinma I Onwuka, Ambrose E Obiechina. Evaluation of urinary hydroxyproline and creatinine level in patients with benign mandibular odontogenic tumor. Clinical and experimental dental research. 2021 10; 7(5):934-940. doi: 10.1002/cre2.392. [PMID: 33496059]
  • Takashi Uebanso, Mai Suyama, Takaaki Shimohata, Kazuaki Mawatari, Akira Takahashi. Effect of Vitamin B2-Deficient Diet on Hydroxyproline- or Obesity-Induced Hyperoxaluria in Mice. Molecular nutrition & food research. 2021 08; 65(15):e2100226. doi: 10.1002/mnfr.202100226. [PMID: 34110671]
  • Artur Pinski, Alexander Betekhtin, Jolanta Kwasniewska, Lukasz Chajec, Elzbieta Wolny, Robert Hasterok. 3,4-Dehydro-L-proline Induces Programmed Cell Death in the Roots of Brachypodium distachyon. International journal of molecular sciences. 2021 Jul; 22(14):. doi: 10.3390/ijms22147548. [PMID: 34299166]
  • Mitra Samareh Fekri, Hamid Reza Poursalehi, Fariba Sharififar, Ali Mandegary, Farzaneh Rostamzadeh, Rahil Mahmoodi. The effects of methanolic extract of Glycyrrhiza glabra on the prevention and treatment of bleomycin-induced pulmonary fibrosis in rat: experimental study. Drug and chemical toxicology. 2021 Jul; 44(4):365-371. doi: 10.1080/01480545.2019.1606232. [PMID: 31072167]
  • Tatsuya Hosono, Masashi Bando, Yoshiko Mizushina, Masafumi Sata, Koichi Hagiwara, Yukihiko Sugiyama. Inhibitory effects of somatostatin analogue in bleomycin-induced pulmonary fibrosis. Experimental lung research. 2021 May; 47(6):280-288. doi: 10.1080/01902148.2021.1916650. [PMID: 33899633]
  • Ruo-Fei Li, Xin-Yue Chen, Yong Xu, Fan-Chao Feng, Hai-Lang He, Xian-Mei Zhou. Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis. Journal of ethnopharmacology. 2021 Apr; 269(?):113761. doi: 10.1016/j.jep.2020.113761. [PMID: 33383114]
  • Georgios Mavropalias, Leslie Calapre, Michael Morici, Tomoko Koeda, Wayne C K Poon, Oliver R Barley, Elin Gray, Anthony J Blazevich, Kazunori Nosaka. Changes in plasma hydroxyproline and plasma cell-free DNA concentrations after higher- versus lower-intensity eccentric cycling. European journal of applied physiology. 2021 Apr; 121(4):1087-1097. doi: 10.1007/s00421-020-04593-1. [PMID: 33439308]
  • Jin Yang, Yunyi Le, Tianjiao Wei, Kangli Wang, Kun Yang, Wenhua Xiao, Tianpei Hong, Rui Wei. Non-targeted metabolomic analysis predicts the therapeutic effects of exenatide on endothelial injury in patients with type 2 diabetes. Journal of diabetes and its complications. 2021 02; 35(2):107797. doi: 10.1016/j.jdiacomp.2020.107797. [PMID: 33293208]
  • Mohd Hafis Yuswan, Nurul Hanani A Jalil, Haslina Mohamad, Shamsidah Keso, Nurhidayatul Asma Mohamad, Tengku Shahrul Tengku Md Yusoff, Nor Falahiah Ismail, Yanty Noorzianna Abdul Manaf, Amalia Mohd Hashim, Mohd Nasir Mohd Desa, Yus Aniza Yusof, Shuhaimi Mustafa. Hydroxyproline determination for initial detection of halal-critical food ingredients (gelatin and collagen). Food chemistry. 2021 Feb; 337(?):127762. doi: 10.1016/j.foodchem.2020.127762. [PMID: 32777563]
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  • Pathomwat Wongrattanakamon, Wipawadee Yooin, Busaban Sirithunyalug, Piyarat Nimmanpipug, Supat Jiranusornkul. Tentative Peptide‒Lipid Bilayer Models Elucidating Molecular Behaviors and Interactions Driving Passive Cellular Uptake of Collagen-Derived Small Peptides. Molecules (Basel, Switzerland). 2021 Jan; 26(3):. doi: 10.3390/molecules26030710. [PMID: 33573083]
  • Hiroki Ohnari, Masatoshi Sekiya, Eiji Naru, Taku Ogura, Osamu Sakata, Yasuko Obata. Amino Acids and Their N-Acetylated Derivatives Maintain the Skin's Barrier Function. Chemical & pharmaceutical bulletin. 2021; 69(7):652-660. doi: 10.1248/cpb.c21-00152. [PMID: 34193714]
  • Yanyong Xu, Xiaoli Pan, Shuwei Hu, Yingdong Zhu, Fathima Cassim Bawa, Yuanyuan Li, Liya Yin, Yanqiao Zhang. Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice. American journal of physiology. Gastrointestinal and liver physiology. 2021 01; 320(2):G166-G174. doi: 10.1152/ajpgi.00315.2020. [PMID: 33325808]
  • Yu Nakanishi, Yasushi Horimasu, Kakuhiro Yamaguchi, Shinjiro Sakamoto, Takeshi Masuda, Taku Nakashima, Shintaro Miyamoto, Hiroshi Iwamoto, Shinichiro Ohshimo, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori. IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis. PloS one. 2021; 16(6):e0252594. doi: 10.1371/journal.pone.0252594. [PMID: 34086758]
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