Cyclophosphamide (BioDeep_00000002219)

 

Secondary id: BioDeep_00000397744

human metabolite blood metabolite


代谢物信息卡片


(+,-)-2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate

化学式: C7H15Cl2N2O2P (260.024816)
中文名称: 环磷酰胺
谱图信息: 最多检出来源 Homo sapiens(blood) 1.45%

分子结构信息

SMILES: C1CNP(=O)(N(CCCl)CCCl)OC1
InChI: InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)

描述信息

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. [PubChem]
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AA - Nitrogen mustard analogues
D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds
D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
D000970 - Antineoplastic Agents > D019653 - Myeloablative Agonists
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant
CONFIDENCE standard compound; INTERNAL_ID 4119
CONFIDENCE standard compound; INTERNAL_ID 2727
D009676 - Noxae > D000477 - Alkylating Agents
D009676 - Noxae > D009153 - Mutagens
D018501 - Antirheumatic Agents

同义名列表

22 个代谢物同义名

(+,-)-2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate; N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide; 2-[bis(2-chloroethyl)amino]-1,3,2lambda5-oxazaphosphinan-2-one; Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester; Monohydrate, cyclophosphamide; Cyclophosphamide, (S)-isomer; Cyclophosphamide, (R)-isomer; Cyclophosphamide monohydrate; Anhydrous, cyclophosphamide; Cyclophosphamide anhydrous; (+-)-Cyclophosphamide; (RS)-Cyclophosphamide; cyclophosphamide; Cyclophosphane; Cytophosphane; Cytophosphan; Sendoxan; Procytox; Cytoxan; Endoxan; Neosar



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(2)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nesma Khaled, Nehal Ibrahim, Alaa E Ali, Fadia S Youssef, Sherweit H El-Ahmady. LC-qTOF-MS/MS phytochemical profiling of Tabebuia impetiginosa (Mart. Ex DC.) Standl. leaf and assessment of its neuroprotective potential in rats. Journal of ethnopharmacology. 2024 Sep; 331(?):118292. doi: 10.1016/j.jep.2024.118292. [PMID: 38705428]
  • Yining He, Heba M Amer, Zonghui Xu, Lin Liu, Shujing Wu, Beihui He, Junqiu Liu, Guoyin Kai. Exploration of the underlying mechanism of Astragaloside III in attenuating immunosuppression via network pharmacology and vitro/vivo pharmacological validation. Journal of ethnopharmacology. 2024 Aug; 330(?):118235. doi: 10.1016/j.jep.2024.118235. [PMID: 38648891]
  • Cuiping Xu, Qionglian Fang, Hao Cui, Yameng Lin, Chunyan Dai, Xiaoxun Li, Pengfei Tu, Xiuming Cui. Comparison of the components of fresh Panax notoginseng processed by different methods and their anti-anemia effects on cyclophosphamide-treated mice. Journal of ethnopharmacology. 2024 Aug; 330(?):118148. doi: 10.1016/j.jep.2024.118148. [PMID: 38583734]
  • Yanjing Huang, Runan Hu, Zhuo Liu, Yuli Geng, Fan Li, Yufan Song, Wenwen Ma, Haoxu Dong, Lijun Xu, Mingmin Zhang, Kunkun Song. Bushen Huoxue recipe ameliorates ovarian function via promoting BMSCs proliferation and homing to ovaries in POI mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155630. doi: 10.1016/j.phymed.2024.155630. [PMID: 38678952]
  • Wenyu Jia, Xuan Lin, Xuezhang Chen, Hongliang Li, Xingru Zhang, Yuzhuo Zhang, Yinsong Chen, Bin Wang, Xikang Chen, Ju Chen, Huaqin Tian. Rujifang inhibits triple-negative breast cancer growth via the PI3K/AKT pathway. Journal of ethnopharmacology. 2024 Jun; 327(?):118011. doi: 10.1016/j.jep.2024.118011. [PMID: 38467320]
  • Chi Ma, Jing Zhao, Guangyong Zheng, Shiyu Wu, Ruijun Wu, Dianping Yu, Jingyu Liao, Hongwei Zhang, Li Liu, Lu Jiang, Fei Qian, Huawu Zeng, Gaosong Wu, Zhenhui Lu, Ji Ye, Weidong Zhang. Qijiao Shengbai Capsule alleviated leukopenia by interfering leukotriene pathway: Integrated network study of multi-omics. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155424. doi: 10.1016/j.phymed.2024.155424. [PMID: 38537441]
  • Hui Chen, Ping Nie, Jingling Li, Yongqi Wu, Bo Yao, Yabing Yang, Gendie E Lash, Ping Li. Cyclophosphamide induces ovarian granulosa cell ferroptosis via a mechanism associated with HO-1 and ROS-mediated mitochondrial dysfunction. Journal of ovarian research. 2024 May; 17(1):107. doi: 10.1186/s13048-024-01434-z. [PMID: 38762721]
  • Kseniya Bushmeleva, Alexandra Vyshtakalyuk, Dmitriy Terenzhev, Timur Belov, Evgeniy Nikitin, Vladimir Zobov. Effect of Flavonols of Aronia melanocarpa Fruits on Morphofunctional State of Immunocompetent Organs of Rats under Cyclophosphamide-Induced Immunosuppression. Biomolecules. 2024 May; 14(5):. doi: 10.3390/biom14050578. [PMID: 38785985]
  • Lin Chen, Qihong Jiang, Shiwei Yao, Chenkai Jiang, Hongling Lu, Wenjun Hu, Shaofang Yu, Mingqian Li, Yongcai Feng, Chin Ping Tan, Xingwei Xiang, Guoxin Shen. Sciadonic acid ameliorates cyclophosphamide-induced immunosuppression by modulating the immune response and altering the gut microbiota. Journal of the science of food and agriculture. 2024 May; 104(7):3902-3912. doi: 10.1002/jsfa.13271. [PMID: 38264943]
  • Young Mi Park, Hak Yong Lee, Dong Yeop Shin, Suk Hun Kim, Yeol Yoo, Min Ji Kim, Min Jung Kim, Hye Jeong Yang, Kwang-Hyun Park. Augmentation of NK-cell activity and immunity by combined natural polyphenols and saccharides in vitro and in vivo. International journal of biological macromolecules. 2024 May; 268(Pt 2):131908. doi: 10.1016/j.ijbiomac.2024.131908. [PMID: 38679269]
  • Pei Yang, Yang Zhai, Qian Liu, Guiyun Cao, Yan Ma, Jiangying Cao, Lihao Zhu, Yuhong Liu. The ameliorative effect on chemotherapy-induced injury and tumor immunosuppressive microenvironment of the polysaccharide from the rhizome of Menispermum dauricum DC. International journal of biological macromolecules. 2024 May; 268(Pt 1):131828. doi: 10.1016/j.ijbiomac.2024.131828. [PMID: 38663694]
  • Mohammad Ali, S N Manjula, Ishfaq Mohiuddin, K Mruthunjaya, Faiyaz Shakeel, Suhail Ahmad Mir, Shahid Ud Din Wani. Noni enhances the anticancer activity of cyclophosphamide and suppresses myelotoxicity and hepatotoxicity in tumor-bearing mice. Journal of cancer research and clinical oncology. 2024 Apr; 150(4):212. doi: 10.1007/s00432-024-05734-1. [PMID: 38662247]
  • Hongmei Chen, Guoyong Zhang, Yan Peng, Yuting Wu, Xin Han, Lingpeng Xie, Honglin Xu, Guanghong Chen, Bin Liu, Tong Xu, Mingjie Pang, Changlei Hu, Huijie Fan, Yiming Bi, Yue Hua, Yingchun Zhou, Songping Luo. Danggui Shaoyao San protects cyclophosphamide-induced premature ovarian failure by inhibiting apoptosis and oxidative stress through the regulation of the SIRT1/p53 signaling pathway. Journal of ethnopharmacology. 2024 Apr; 323(?):117718. doi: 10.1016/j.jep.2024.117718. [PMID: 38181933]
  • Xin Liu, Mingyuan Dong, Yuan Li, Lanzhou Li, Yongfeng Zhang, Andong Zhou, Di Wang. Structural characterization of Russula griseocarnosa polysaccharide and its improvement on hematopoietic function. International journal of biological macromolecules. 2024 Apr; 263(Pt 1):130355. doi: 10.1016/j.ijbiomac.2024.130355. [PMID: 38395281]
  • Yuan-Yuan Lei, Yu-Han Ye, Ying Liu, Jia-Ling Xu, Cheng-Lin Zhang, Chun-Ming Lyu, Chen-Guo Feng, Yan Jiang, Yang Yang, Yan Ke. Achyranthes bidentata polysaccharides improve cyclophosphamide-induced adverse reactions by regulating the balance of cytokines in helper T cells. International journal of biological macromolecules. 2024 Apr; 265(Pt 2):130736. doi: 10.1016/j.ijbiomac.2024.130736. [PMID: 38479672]
  • Yan Zhang, Qirui Xu, Yazi Wang, Chenchen Zhang, Shan Xu, Manhong Luo, Shuhan Yang. Caragana sinica (Buc'hoz) Rehd. (jin ji er) polysaccharide regulates the immune function and intestinal microbiota of cyclophosphamide (CTX) induced immunosuppressed mice. Journal of ethnopharmacology. 2024 Mar; 322(?):117551. doi: 10.1016/j.jep.2023.117551. [PMID: 38081398]
  • Mengqi Shi, Tianshi Li, Yan Zhao, Zhongmei He, Ying Zong, Weijia Chen, Rui Du. Comparative studies on the chemical composition and pharmacological effects of vinegar-processed antler glue modified from Lei Gong Pao Zhi Lun and traditional water-processed antler glue. Journal of ethnopharmacology. 2024 Mar; 321(?):117508. doi: 10.1016/j.jep.2023.117508. [PMID: 38065351]
  • Zongping Zhu, Yirong Luo, Liting Lin, Tianhui Gao, Qingsong Yang, Yunqiu Fan, Shuyi Wang, Chaomei Fu, Wan Liao. Modulating Effects of Turmeric Polysaccharides on Immune Response and Gut Microbiota in Cyclophosphamide-Treated Mice. Journal of agricultural and food chemistry. 2024 Feb; 72(7):3469-3482. doi: 10.1021/acs.jafc.3c05590. [PMID: 38329061]
  • Willian Ayala Correa, Silvia Cordeiro das Neves, Rodrigo Juliano Oliveira, Cândida A Kassuya, Stephanie D Navarro, Allana Cristina Faustino Martins, Baby Saroja, Barbara Mitsuyasu, Ingridhy Ostaciana Maia Freitas da Silveira, Neimar Vitor, Henrique Rodrigues Scherer Coelho, Marcelo L B Vilela, Valter A do Nascimento, Dênis P de Lima, Adilson Beatriz, Roberto da Silva Gomes. Chemotherapeutic Mechanism of Action of the Synthetic Resorcinolic Methyl 3,5-dimethoxy-2-octanoylbenzoate. Chemical research in toxicology. 2024 02; 37(2):259-273. doi: 10.1021/acs.chemrestox.3c00269. [PMID: 38183658]
  • Yan-Hong Cui, Lin Ma, Dong-Mei Hai, Yan-Nan Chi, Wen-Jing Dong, Xiao-Bing Lan, Wei Wei, Miao-Miao Tian, Xiao-Dong Peng, Jian-Qiang Yu, Ning Liu. Asperosaponin VI protects against spermatogenic dysfunction in mice by regulating testicular cell proliferation and sex hormone disruption. Journal of ethnopharmacology. 2024 Feb; 320(?):117463. doi: 10.1016/j.jep.2023.117463. [PMID: 37981113]
  • Qianshuang Geng, Jie Li, Xi Li, Wenjie Zhang, Guoxiang Zhang, Li Ge, Li Liang. A case report: Nonsecretory multiple myeloma presenting with bone pain. Medicine. 2024 Feb; 103(5):e36951. doi: 10.1097/md.0000000000036951. [PMID: 38306571]
  • Hong Che, Linlin Li, Bingjie Zhao, Lian Hu, Li Xiao, Peijia Liu, Songshan Liu, Zhufa Hou. Asperuloside alleviates cyclophosphamide-induced myelosuppression by promoting AMPK/mTOR pathway-mediated autophagy. Journal of biochemical and molecular toxicology. 2024 Feb; 38(2):e23641. doi: 10.1002/jbt.23641. [PMID: 38348709]
  • Ngozi Dorathy Idoko, Ifeoma Felicia Chukwuma, Florence Nkechi Nworah, Sopuruchukwu Elizabeth Mba, Parker Elijah Joshua, Okwesilieze Fred Chiletugo Nwodo, Wafaa Fouzi Abusudah, Najlaa Hamed Almohmadi, Michel de Waard. Immunomodulatory effects of epiphytic Loranthus micranthus leaf extracts collected from two host plants: Psidium guajava and Parkia biglobosa. BMC complementary medicine and therapies. 2024 Jan; 24(1):7. doi: 10.1186/s12906-023-04282-4. [PMID: 38166988]
  • Meiling Shi, Hongyan Pei, Li Sun, Weijia Chen, Ying Zong, Yan Zhao, Rui Du, Zhongmei He. Optimization of the Flavonoid Extraction Process from the Stem and Leaves of Epimedium Brevicornum and Its Effects on Cyclophosphamide-Induced Renal Injury. Molecules (Basel, Switzerland). 2023 Dec; 29(1):. doi: 10.3390/molecules29010207. [PMID: 38202790]
  • Evelin Bachmeier, Fernando Martin Wietz, Daniela Josefina Porta, Lorena Moine, Claudio Gastón Dubersarsky, Catalina Melchora Francia, Maria Elena Samar, Maria Angelica Rivoira, Marcelo Adrian Mazzeo. [Melatonin reverses oxidative damage in the submandibular gland of rats treated with Cyclophosphamide]. Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina). 2023 12; 80(4):404-419. doi: 10.31053/1853.0605.v80.n4.40930. [PMID: 38150204]
  • Shu Lian, Wulin Li, Chunlian Zhong, Ye Li, Changhui Wu, Kun Zhang, Jiangfei Lin, Weiyu Wang, Vladimir Katanaev, Xiaodong Xie, Lee Jia. Ganoderma lucidum spore oil synergistically enhances the function of cyclophosphamide in the prevention of breast cancer metastasis. Journal of the Chinese Medical Association : JCMA. 2023 Dec; ?(?):. doi: 10.1097/jcma.0000000000001038. [PMID: 38109372]
  • Yiqiao Gao, Yixin Zhang, Wei Liu, Nan Zhang, Qinghe Gao, Jingfang Shangguan, Na Li, Ying Zhao, Yanlong Jia. Danggui Buxue decoction alleviates cyclophosphamide-induced myelosuppression by regulating β-hydroxybutyric acid metabolism and suppressing oxidative stress. Pharmaceutical biology. 2023 Dec; 61(1):710-721. doi: 10.1080/13880209.2023.2201606. [PMID: 37096658]
  • Ronglin Gao, Jincheng Pu, Yanqing Wang, Zhenzhen Wu, Yuanyuan Liang, Jiamin Song, Shengnan Pan, Fang Han, Lufei Yang, Xianghuai Xu, Jianping Tang, Xuan Wang. Tofacitinib in the treatment of primary Sjögren's syndrome-associated interstitial lung disease: study protocol for a prospective, randomized, controlled and open-label trial. BMC pulmonary medicine. 2023 Nov; 23(1):473. doi: 10.1186/s12890-023-02774-0. [PMID: 38007449]
  • Omyma Rabie, Heba A S El-Nashar, Mina Y George, Taghreed A Majrashi, Tarfah Al-Warhi, Fatma E Hassan, Wagdy M Eldehna, Nada M Mostafa. Phytochemical profiling and neuroprotective activity of Callistemon subulatus leaves against cyclophosphamide-induced chemobrain. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Nov; 167(?):115596. doi: 10.1016/j.biopha.2023.115596. [PMID: 37797461]
  • S A Gabr, W M Elsaed, M A Eladl, G A Ghoniem, M El-Sherbiny, K S El-Bayoumi, H Abouhish, A M Desouky, M M Abdel-Aziz, M Eldesoqui, M Elshafey, H A Ebrahim, N S Nosseir, A M R El-Sayed. Circulating microRNAs as novel biomarkers for measuring the potency of ginger extract against cyclophosphamide toxicity in rat renal tissues: molecular and histopathological study. European review for medical and pharmacological sciences. 2023 Nov; 27(22):10815-10830. doi: 10.26355/eurrev_202311_34448. [PMID: 38039010]
  • Irfan Anjum, Daanyaal Ali, Mohammed Bourhia, Mueen Ahmad Chaudhry, Farhan Siddique, Mehvish Bibi, Abdel-Rhman Z Gaafar, Touriya Zair, Farid Khallouki. Cuminum cyminum Ameliorates Urotoxic Effects of Cyclophosphamide by Modulating Antioxidant, Inflammatory Cytokines, and Urinary Bladder Overactivity: In vivo and in Silico Investigations. Chemistry & biodiversity. 2023 Oct; ?(?):e202301268. doi: 10.1002/cbdv.202301268. [PMID: 37843082]
  • Yuan Zhao, Jinru Wu, Xiangbin Li, Qiugu Chen, Zhiming Hong, Lin Zheng, Shiying Huang, Pingli Mo, Changhui Li, Rui Wang, Qiuyan Guo, Shangbin Zhang, Jianping Chen. Protective effect of Huangqi-Guizhi-Wuwutang against cyclophosphamide-induced spermatogenesis dysfunction in mice by promoting steroid hormone biosynthesis. Journal of ethnopharmacology. 2023 Oct; 319(Pt 2):117260. doi: 10.1016/j.jep.2023.117260. [PMID: 37813291]
  • Qigang Fan, Ruifen He, Yi Li, Pu Gao, Runchun Huang, Rong Li, Jiayu Zhang, Hongli Li, Xiaolei Liang. Studying the effect of hyperoside on recovery from cyclophosphamide induced oligoasthenozoospermia. Systems biology in reproductive medicine. 2023 Oct; 69(5):333-346. doi: 10.1080/19396368.2023.2241600. [PMID: 37578152]
  • Jing-Nan Yan, Ke Ma, Wen-Jie Liu, Ying Lin, Xiu-Yu Li, Dan Wu. [Blaps rynchopetera combined with cyclophosphamide affects proliferation and apoptosis of lung cancer cells via Wnt/β-catenin signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Oct; 48(20):5603-5611. doi: 10.19540/j.cnki.cjcmm.20230712.701. [PMID: 38114153]
  • Yi Mu, Bangwei Che, Kaifa Tang, Wenjun Zhang, Shenghan Xu, Wei Li, Jun He, Miao Liu, Peng Chen, Siwen Zhong, Guangyu Li. Dendrobium officinale polysaccharides improved reproductive oxidative stress injury in male mice treated with cyclophosphamide. Environmental science and pollution research international. 2023 Sep; ?(?):. doi: 10.1007/s11356-023-29874-y. [PMID: 37728673]
  • Zhimin Mao, Kun Zhong, Xiaojun Liu, Xuhui Zeng. Ferroptosis contributes to cyclophosphamide-induced hemorrhagic cystitis. Chemico-biological interactions. 2023 Sep; ?(?):110701. doi: 10.1016/j.cbi.2023.110701. [PMID: 37690746]
  • Arzu Keskin-Aktan, Özden Kutlay. Exogenous apelin-13 administration ameliorates cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in rat lungs. Protein and peptide letters. 2023 Aug; ?(?):. doi: 10.2174/0929866530666230824142516. [PMID: 37622713]
  • H X Liu, D L Wei, S Shao, Y Jiang, S Li, J Zhu, C Wang, C X Zhao. [Impact of immunosuppression intensified conditioning regimen for patients with strong positive pre-transplantation donor-specific anti-HLA antibodies (DSAs) undergoing haploidentical hematopoietic stem cell transplantation]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 2023 Aug; 44(8):654-659. doi: 10.3760/cma.j.issn.0253-2727.2023.08.007. [PMID: 37803839]
  • Z Y Shen, X C Chen, H R Shan, T Jia, W Y Gu, F Wang, Q L Teng, L Wang, C L Wang, Y Y Shi, H Zhang, Y Q Miao, T G Zhu, C Y Ji, J J Ye, M Z Zhang, X D Zhang, L Wang, K L Xu, W Sang. [Analysis of prognostic factors of extranodal NK/T-cell lymphoma treated with pegaspargase/L-asparaginase: a multicenter retrospective study]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 2023 Aug; 44(8):642-648. doi: 10.3760/cma.j.issn.0253-2727.2023.08.005. [PMID: 37803837]
  • He Zhang, Yue Sun, Meiling Fan, Yuyao Zhang, Zuguo Liang, Lancao Zhang, Xiang Gao, Xinzhu He, Xiangyan Li, Daqing Zhao, Gianni Sagratini, Hang Su, Wenxiu Qi. Prevention effect of total ginsenosides and ginseng extract from Panax ginseng on cyclophosphamide-induced immunosuppression in mice. Phytotherapy research : PTR. 2023 Aug; 37(8):3583-3601. doi: 10.1002/ptr.7836. [PMID: 37070654]
  • Elnaz Jahanbani Mazraeh, Sanambar Sadighi, Soheila Manifar, Hooman Bakhshandeh, Mehdi Rajabi. Assessment of thyme honey oral gel for the prevention of adriamycin and cyclophosphamide chemotherapy-induced oral mucositis in patients with breast cancer. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2023 Jul; 31(8):497. doi: 10.1007/s00520-023-07943-9. [PMID: 37505326]
  • R Xu, S Li, H X Liu, D L Wei, Y Jiang, J J Wang, S S Liu, C Wang, J Zhu. [Efficacy and safety of TBI+rATG-based conditioning regimen for haploidentical allogeneic hematopoietic stem cell transplantation in 11 cases of chemotherapy-resistant advanced peripheral T-cell lymphoma]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 2023 Jul; 44(7):578-581. doi: 10.3760/cma.j.issn.0253-2727.2023.07.010. [PMID: 37749039]
  • Yunjie Yang, Zhenduo Shi, Hui Yu, Mengzhen Liu, Tianhui Hu, Conghui Han. Si-Ni-San Ameliorates the Clinical Symptoms of Interstitial Cystitis/Bladder Pain Syndrome in Rats by Decreasing the Expression of Inflammatory Factors. Archivos espanoles de urologia. 2023 Jul; 76(5):347-356. doi: 10.56434/j.arch.esp.urol.20237605.41. [PMID: 37545154]
  • Mohammad Ghasem Golmohammadi, Shokofeh Banaei, Mojgan Timar, Ali Abedi. Saponin protects against cyclophosphamide-induced kidney and liver damage via antioxidant and anti-inflammatory actions. Physiology international. 2023 Jun; 110(2):108-120. doi: 10.1556/2060.2023.00190. [PMID: 37256739]
  • Adejoke Y Onaolapo, Foluso O Ojo, Olakunle J Onaolapo. Biflavonoid quercetin protects against cyclophosphamide-induced organ toxicities via modulation of inflammatory cytokines, brain neurotransmitters, and astrocyte immunoreactivity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Jun; 178(?):113879. doi: 10.1016/j.fct.2023.113879. [PMID: 37301500]
  • Yulong Ye, Chunyan Fang, Lanying Li, Dongna Liu, Yingchun Wang, Fan Huang, Xuejiao Gong, Yaqiong Xu, Yu Yao, Shanrong Ye, Dejian Feng, Fan Luo. Protective Effect of l-Theanine on Cyclophosphamide-Induced Testicular Toxicity in Mice. Journal of agricultural and food chemistry. 2023 May; ?(?):. doi: 10.1021/acs.jafc.3c01010. [PMID: 37198140]
  • Nan Hu, Yue Qu, Ting-Yu Liu, Yue Zhou, Chang Liu, Jin-Hui Wang, Bao-Feng Yang, Chun-Li Li. Immunomodulatory effects and mechanisms of Tiepishihu Xiyangshen granules on cyclophosphamide induced immuno-suppression via TLR4/MAPKs and PI3K/AKT/FOXO3a signal pathways. Journal of ethnopharmacology. 2023 May; 307(?):116192. doi: 10.1016/j.jep.2023.116192. [PMID: 36706933]
  • Yanan Li, Junping Zheng, Yao Wang, Huabing Yang, Lu Cao, Shuiyong Gan, Jun Ma, Hongtao Liu. Immuno-stimulatory activity of Astragalus polysaccharides in cyclophosphamide-induced immunosuppressed mice by regulating gut microbiota. International journal of biological macromolecules. 2023 May; 242(Pt 2):124789. doi: 10.1016/j.ijbiomac.2023.124789. [PMID: 37164141]
  • Yeneng Guan, Aqin Yan, Wei Qiang, Rui Ruan, Chaobo Yang, Kai Ma, Hongmei Sun, Mingxing Liu, Hongda Zhu. Selective Delivery of Tofacitinib Citrate to Hair Follicles Using Lipid-Coated Calcium Carbonate Nanocarrier Controls Chemotherapy-Induced Alopecia Areata. International journal of molecular sciences. 2023 May; 24(9):. doi: 10.3390/ijms24098427. [PMID: 37176141]
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