Clarithromycin (BioDeep_00000002154)

 

Secondary id: BioDeep_00000397468

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione

化学式: C38H69NO13 (747.4769)
中文名称: (14R)-14-羟基克拉霉素, 克拉霉素
谱图信息: 最多检出来源 Homo sapiens(blood) 4.05%

分子结构信息

SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)O
InChI: InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1

描述信息

Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01F - Macrolides, lincosamides and streptogramins > J01FA - Macrolides
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065692 - Cytochrome P-450 CYP3A Inhibitors
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic
CONFIDENCE standard compound; EAWAG_UCHEM_ID 191
EAWAG_UCHEM_ID 191; CONFIDENCE standard compound
C254 - Anti-Infective Agent > C258 - Antibiotic
CONFIDENCE standard compound; INTERNAL_ID 1053
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

18 个代谢物同义名

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dion; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl)oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-quinone; 6-[4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione; hydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexame; 6-O-Methylerythromycin a; 6-O-Methylerythromycin; Clarithromycinum; Clarithromycina; Clarithromycine; Clarithromycin; Clathromycin; Klaricid; Biaxin; CLA; CAM; Clarithromycin



数据库引用编号

39 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ABCB1, ALB, CAT, CYP2C19, CYP2C9, CYP3A4, MEFV
Endoplasmic reticulum membrane 5 CD4, CYP2C19, CYP2C9, CYP3A4, CYP3A5
Cytoplasmic vesicle, autophagosome 1 MEFV
Nucleus 3 ALB, MEFV, MPO
autophagosome 1 MEFV
cytosol 4 ALB, CAT, IL1B, MEFV
centrosome 1 ALB
nucleoplasm 2 MEFV, MPO
Cell membrane 4 ABCB1, CD4, NTM, TNF
lamellipodium 1 MEFV
Multi-pass membrane protein 3 ABCB1, ATP4A, CACNA1I
cell surface 2 ABCB1, TNF
Golgi apparatus 1 ALB
Golgi membrane 1 INS
neuronal cell body 1 TNF
Cytoplasm, cytosol 1 IL1B
Lysosome 2 IL1B, MPO
plasma membrane 10 ABCB1, ATP4A, CACNA1I, CD4, CSF2, CYP2C19, CYP2C9, IFNLR1, NTM, TNF
Membrane 7 ABCB1, ATP4A, CACNA1I, CAT, CYP3A4, CYP3A5, IFNLR1
apical plasma membrane 2 ABCB1, ATP4A
extracellular exosome 4 ABCB1, ALB, CAT, MPO
endoplasmic reticulum 1 ALB
extracellular space 9 ALB, ATP4A, CRP, CSF2, IL1B, IL6, INS, MPO, TNF
mitochondrion 1 CAT
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 7 CAT, CSF2, CYP2C19, CYP2C9, CYP3A4, CYP3A5, MPO
Microsome membrane 3 CYP2C9, CYP3A4, CYP3A5
Single-pass type I membrane protein 2 CD4, IFNLR1
Secreted 6 ALB, CRP, CSF2, IL1B, IL6, INS
extracellular region 10 ALB, CAT, CRP, CSF2, IL1B, IL6, INS, MPO, NTM, TNF
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
external side of plasma membrane 2 CD4, TNF
cytoplasmic vesicle 1 MEFV
Early endosome 1 CD4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 2 ABCB1, ATP4A
Cell projection, lamellipodium 1 MEFV
Membrane raft 2 CD4, TNF
focal adhesion 1 CAT
microtubule 1 MEFV
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 2 IL1B, MPO
Cell projection, ruffle 1 MEFV
ruffle 1 MEFV
ciliary basal body 1 ALB
microtubule associated complex 1 MEFV
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Lipid-anchor, GPI-anchor 1 NTM
endosome lumen 1 INS
side of membrane 1 NTM
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, CD4, IL6, INS
platelet alpha granule lumen 1 ALB
voltage-gated calcium channel complex 1 CACNA1I
transport vesicle 1 INS
Secreted, extracellular exosome 1 IL1B
azurophil granule lumen 1 MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 CD4
phagocytic vesicle lumen 1 MPO
[Isoform 2]: Nucleus 1 MEFV
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cytoplasm, cytoskeleton 1 MEFV
canonical inflammasome complex 1 MEFV
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
potassium:proton exchanging ATPase complex 1 ATP4A
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Kiarash Ghazvini, Hossein Kamali, Hadi Farsiani, Masoud Yousefi, Masoud Keikha. Sustain-release lipid-liquid crystal formulations of pexiganan against Helicobacter pylori infection: in vitro evaluation in C57BL/6 mice. BMC pharmacology & toxicology. 2024 01; 25(1):9. doi: 10.1186/s40360-024-00731-z. [PMID: 38212864]
  • Variya Nemidkanam, Wijit Banlunara, Nuntaree Chaichanawongsaroj. Kaempferia parviflora Extracellular Vesicle Loaded with Clarithromycin for the Treatment of Helicobacter pylori Infection. International journal of nanomedicine. 2024; 19(?):1967-1983. doi: 10.2147/ijn.s444686. [PMID: 38435753]
  • Ying-Ying Han, Lin Zhou, Yun-Lian Hu, Xiang-Wu Ding, Hui Long, Fei Liu, Ming Xu, Zhen-Yu Zhang, Shuang-Ling Li, Qiu-Yan Wang, Cheng-Xia Su, Yan Chen, Jie Chen, Ya Lin, Pei-Yuan Li. Comparison of vonoprazan-based with rabeprazole-based dual therapy for treatment-naive patients of Helicobacter pylori infection: a prospective, multi-center, randomized controlled study. Journal of gastroenterology. 2023 Oct; ?(?):. doi: 10.1007/s00535-023-02042-2. [PMID: 37777987]
  • Lucía Rodríguez-López, Vanesa Santás-Miguel, Raquel Cela-Dablanca, Avelino Núñez-Delgado, Esperanza Álvarez-Rodríguez, Andrés Rodríguez-Seijo, Manuel Arias-Estévez. Clarithromycin as soil and environmental pollutant: Adsorption-desorption processes and influence of pH. Environmental research. 2023 09; 233(?):116520. doi: 10.1016/j.envres.2023.116520. [PMID: 37390951]
  • Yuxiang Wang, Jinran Du, Dayan Zhang, Cong Jin, Jiangpo Chen, Zeyuan Wang, Tonglin Mei, Kaili Fu, Qingzeng Qian, Tieliang Pang. Primary antibiotic resistance in Helicobacter pylori in China: a systematic review and meta-analysis. Journal of global antimicrobial resistance. 2023 09; 34(?):30-38. doi: 10.1016/j.jgar.2023.05.014. [PMID: 37315738]
  • Shasha Chen, Weina Shen, Yuhuan Liu, Qiang Dong, Yongquan Shi. Efficacy and safety of triple therapy containing berberine, amoxicillin, and vonoprazan for Helicobacter pylori initial treatment: A randomized controlled trial. Chinese medical journal. 2023 Jul; 136(14):1690-1698. doi: 10.1097/cm9.0000000000002696. [PMID: 37469024]
  • J M Castaño-Ortiz, R Gil-Solsona, N Ospina-Alvarez, M M García-Pimentel, V M León, L H M L M Santos, D Barceló, S Rodríguez-Mozaz. Bioaccumulation and fate of pharmaceuticals in a Mediterranean coastal lagoon: Temporal variation and impact of a flash flood event. Environmental research. 2023 07; 228(?):115887. doi: 10.1016/j.envres.2023.115887. [PMID: 37054836]
  • Shengjuan Hu, Yan Zhou, Yanhong Deng, Yang Bo, Xianmei Chen, Wei Yang, Ruichun Shi, Wei Zhao, Zhanbing Hou, Jianping Hu, Jianguo Liu, Xilong Zhang, Heli Yong, Ping Wang, Fei Li, Hailong Qi, Xiaoyun Wang, Lijuan Jin, Ting Cui, Haijiang Yong, Xue Li, Bin Yang, Yuehua Yu, Bin Ma, Lei Fu, Xuemei Wang, Zhen Ma, Na Tang, Yanjie You, Jianyang Guo, Xiaobing Yu, Li Yao, Ruiping Gao, Yanling Li, Ruijuan Xin, Jianfang Liu, Zhenzi Cao, Hongliang Li, Linke Ma, Shoucheng Ma, Ying Cao, Yuanyuan Tang, Jun Liu, Qian Hao, Xiaofei Li, Xuemei Li, Rui Mu, Min Niu, Xiaoming Su, Hengjun Gao. Characteristics of phenotypic antibiotic resistance of Helicobacter pylori and its correlation with genotypic antibiotic resistance: A retrospective study in Ningxia. Helicobacter. 2023 Jun; 28(3):e12960. doi: 10.1111/hel.12960. [PMID: 37042045]
  • Bahar Ikizoglu, Fatma Ilter Turkdogan, Gurdal Kanat, Coskun Aydiner. Seasonal analysis of commonly prescribed antibiotics in Istanbul city. Environmental monitoring and assessment. 2023 Apr; 195(5):566. doi: 10.1007/s10661-023-11203-y. [PMID: 37058249]
  • Xueping Huang, Baihe Wu, Qiuzhao Chen, Yushan Chen, Xinhua Ji, Xiang Zhou, Biao Suo, Zhihui Lin, Xiaoling Zheng. Antibiotic resistance profile of Helicobacter pylori to 14 antibiotics: a multicenter study in Fujian, China. PeerJ. 2023; 11(?):e15611. doi: 10.7717/peerj.15611. [PMID: 37456872]
  • Aiman A Shoiab, Ali Alsarhan, Ashraf O Khashroum. EFFECT OF PHARMACIST COUNSELING ON PATIENT MEDICATION COMPLIANCE AND HELICOBACTER PYLORI ERADICATION AMONG JORDANIAN OUTPATIENTS. Arquivos de gastroenterologia. 2023 Jan; 60(1):74-83. doi: 10.1590/s0004-2803.202301000-10. [PMID: 37194783]
  • Haoqi Wang, Nirmitee Mulgaonkar, Samavath Mallawarachchi, Manikandan Ramasamy, Carmen S Padilla, Sonia Irigoyen, Gitta Coaker, Kranthi K Mandadi, Sandun Fernando. Evaluation of Candidatus Liberibacter Asiaticus Efflux Pump Inhibition by Antimicrobial Peptides. Molecules (Basel, Switzerland). 2022 Dec; 27(24):. doi: 10.3390/molecules27248729. [PMID: 36557860]
  • Guoxin Bai, Junyu Yi, Yuanyuan Yu, Hongxing Du. Clinical effect of Anwei Qingyou recipe on peptic ulcer and its effect on the levels of EGF and PGE2: A retrospective study. Medicine. 2022 Oct; 101(40):e30898. doi: 10.1097/md.0000000000030898. [PMID: 36221352]
  • Stella G Michael, Barbara Drigo, Irene Michael-Kordatou, Costas Michael, Thomas Jäger, Samuel C Aleer, Thomas Schwartz, Erica Donner, Despo Fatta-Kassinos. The effect of ultrafiltration process on the fate of antibiotic-related microcontaminants, pathogenic microbes, and toxicity in urban wastewater. Journal of hazardous materials. 2022 08; 435(?):128943. doi: 10.1016/j.jhazmat.2022.128943. [PMID: 35650718]
  • Yuan-Yuan Dai, Chun Qin, Gan-Rong Huang, Yan-Chun Qin, Yong-Yi Huang, Yan-Qiang Huang, Li-Juan Zhao. Linolenic Acid-Metronidazole: a Compound Relieving Drug Resistance and Inhibiting Helicobacter pylori. Antimicrobial agents and chemotherapy. 2022 07; 66(7):e0007322. doi: 10.1128/aac.00073-22. [PMID: 35758720]
  • Eleonora Altman, Vandana Chandan, Blair A Harrison, Melissa Schur, Marie-France Goneau, Jianjun Li, Michel Gilbert. Chemoenzymatic synthesis of an α-1,6-glucan-based conjugate vaccine against Helicobacter pylori. Glycobiology. 2022 Jul; 32(8):691-700. doi: 10.1093/glycob/cwac023. [PMID: 35436341]
  • Timothy Arthur Chandos Snow, Alessia Longobardo, David Brealey, Jim Down, Giovanni Satta, Mervyn Singer, Nishkantha Arulkumaran. Beneficial ex vivo immunomodulatory and clinical effects of clarithromycin in COVID-19. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022 Jul; 28(7):948-954. doi: 10.1016/j.jiac.2022.04.001. [PMID: 35440370]
  • Chen Yang, Sai Li, Taoyang Huang, Hongju Lin, Zhihui Jiang, Yongyang He, Junjie Yuan, Huijie An. Effectiveness and safety of vonoprazan-based regimen for Helicobacter pylori eradication: A meta-analysis of randomized clinical trials. Journal of clinical pharmacy and therapeutics. 2022 Jul; 47(7):897-904. doi: 10.1111/jcpt.13637. [PMID: 35247003]
  • Ryo Yonezawa, Tomiko Sunaga. Signal of safety due to adverse drug reactions induced by tacrolimus with or without azithromycin. Transplant infectious disease : an official journal of the Transplantation Society. 2022 Jun; 24(3):e13833. doi: 10.1111/tid.13833. [PMID: 35385596]
  • Pei-Qian Wu, Yong-Sheng Cui, Xiao-Ying Han, Chen Wang, Pei-Pei An, Jun-Su Zhou, Yu-Hao Ren, Zhen-Long Liu, Rong-Tuan Lin, Bin Zhou, Jian-Min Yue. Diterpenoids from Sauropus spatulifolius Leaves with Antimicrobial Activities. Journal of natural products. 2022 05; 85(5):1304-1314. doi: 10.1021/acs.jnatprod.2c00020. [PMID: 35427111]
  • Eva C Arrua, Sofía V Sanchez, Valeria Trincado, Antonio Hidalgo, Andrew F G Quest, Javier O Morales. Experimental design and optimization of a novel dual-release drug delivery system with therapeutic potential against infection with Helicobacter pylori. Colloids and surfaces. B, Biointerfaces. 2022 May; 213(?):112403. doi: 10.1016/j.colsurfb.2022.112403. [PMID: 35219219]
  • Mingming Xu, Junfei Zhou, Ding Heng, Xiaorong Su, Monday M Onakpa, Yuefan Bai, Jin-Ao Duan, Chun-Tao Che, Hongkai Bi, Ming Zhao. Quinone Derivatives as Promising Anti-Helicobacter pylori Agents from Aerial Parts of Mitracarpus hirtus. Journal of natural products. 2022 04; 85(4):1029-1038. doi: 10.1021/acs.jnatprod.1c01163. [PMID: 35412828]
  • Saranya Poapolathep, Mario Giorgi, Narumol Klangkaew, Kraisiri Khidkhan, Narongsak Chaiyabutr, Tara Wongwaipairoj, Amnart Poapolathep. Pharmacokinetic profiles of clarithromycin in freshwater crocodiles (Crocodylus siamensis). Journal of veterinary pharmacology and therapeutics. 2022 Mar; 45(2):147-152. doi: 10.1111/jvp.13034. [PMID: 34845734]
  • Amna Arshad, Ikram Ullah Khan, Moazam Ali, Fatima Arshad, Adeela Riaz, Zeeshan Ahmad Bhutta, Ambreen Ashar. Probing the Synergistic Effect of Antibacterial Drug and Oleic Acid in Lipid-based Gastroretentive Matrices by Melt Molding Method. Current drug delivery. 2022; 20(1):89-97. doi: 10.2174/1567201819666220412112104. [PMID: 35418284]
  • Ki Young Huh, Hyewon Chung, Yu Kyong Kim, SeungHwan Lee, Siddharth Bhatia, Yohei Takanami, Ryou Nakaya, Kyung-Sang Yu. Evaluation of safety and pharmacokinetics of bismuth-containing quadruple therapy with either vonoprazan or lansoprazole for Helicobacter pylori eradication. British journal of clinical pharmacology. 2022 01; 88(1):138-144. doi: 10.1111/bcp.14934. [PMID: 34080718]
  • Osamu Iketani, Akari Komeya, Yuki Enoki, Kazuaki Taguchi, Shunsuke Uno, Yoshifumi Uwamino, Kazuaki Matsumoto, Junko Kizu, Naoki Hasegawa. Impact of rifampicin on the pharmacokinetics of clarithromycin and 14-hydroxy clarithromycin in patients with multidrug combination therapy for pulmonary Mycobacterium avium complex infection. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022 Jan; 28(1):61-66. doi: 10.1016/j.jiac.2021.10.003. [PMID: 34706852]
  • Yalda Lucero, Anne J Lagomarcino, Juan P Torres, Patricia Roessler, Nora Mamani, Sergio A George, Nicole Huerta, Mónica González, Miguel O'Ryan G. Effect of Helicobacter pylori eradication therapy on clinical and laboratory biomarkers associated with gastric damage in healthy school-aged children: A randomized non-blinded trial. Helicobacter. 2021 Dec; 26(6):e12853. doi: 10.1111/hel.12853. [PMID: 34528337]
  • Ryohei Hirano, Akitomo Yokokawa, Tomomi Furihata, Hiromi Shibasaki. Dried blood spots analysis of 6β-hydroxycortisol and cortisol using liquid chromatography/tandem mass spectrometry for calculating 6β-hydroxycortisol to cortisol ratio. Journal of mass spectrometry : JMS. 2021 Dec; 56(12):e4790. doi: 10.1002/jms.4790. [PMID: 34881490]
  • Sheng Kuang, Jinkang Xu, Miaomiao Chen, Yongliang Zhang, Fangzhen Shi, Xirong Lu. The influence of pretreatment with PPI on Helicobacter pylori eradication: A systematic review and meta-analysis. Medicine. 2021 Nov; 100(47):e27944. doi: 10.1097/md.0000000000027944. [PMID: 34964772]
  • Yinhui Qin, Linlin Xu, Yuetai Teng, Yan Yang, Yinhu Wang, Peizhi Ma. Design, synthesis and antibacterial evaluation of novel 3-O-substituted 15-membered azalides possessing 1,2,3-triazole side chains. Bioorganic & medicinal chemistry letters. 2021 10; 49(?):128330. doi: 10.1016/j.bmcl.2021.128330. [PMID: 34403726]
  • Ken Kurosawa, Stefaan Rossenu, Jeike Biewenga, Sivi Ouwerkerk-Mahadevan, Wouter Willems, Etienne Ernault, Chrispin Kambili. Population Pharmacokinetic Analysis of Bedaquiline-Clarithromycin for Dose Selection Against Pulmonary Nontuberculous Mycobacteria Based on a Phase 1, Randomized, Pharmacokinetic Study. Journal of clinical pharmacology. 2021 10; 61(10):1344-1355. doi: 10.1002/jcph.1887. [PMID: 33991350]
  • Kazuko Yamamoto, Naoki Hosogaya, Noriho Sakamoto, Haruo Yoshida, Hiroshi Ishii, Kazuhiro Yatera, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae. Efficacy of clarithromycin in patients with mild COVID-19 pneumonia not receiving oxygen administration: protocol for an exploratory, multicentre, open-label, randomised controlled trial (CAME COVID-19 study). BMJ open. 2021 09; 11(9):e053325. doi: 10.1136/bmjopen-2021-053325. [PMID: 34548368]
  • N Takemori, H K Ooi, G Imai, M Saio. Diverse effects of clarithromycin and proposal of its clinical application for treating COVID-19 as a repurposing drug. Tropical biomedicine. 2021 Sep; 38(3):343-352. doi: 10.47665/tb.38.3.077. [PMID: 34508342]
  • Allison Kirchner, Artem Sergeyenko, Janice Keane, Kenneth Belinski, Wenhua Liu. Diagnosis of cutaneous mycobacterial spindle cell pseudotumor in the absence of typical inflammatory cells: A case report. Journal of cutaneous pathology. 2021 Sep; 48(9):1178-1181. doi: 10.1111/cup.14042. [PMID: 33948982]
  • Alaa Rashad, Asmaa Nafady, Mohammed H Hassan, Haggagy Mansour, Usama Taya, Shamardan Ezzeldin S Bazeed, Zaki F Aref, Mennatallah Ali Abdelrhman Sayed, Hanaa Nafady-Hego, Aida A Abdelmaksoud. Therapeutic efficacy of macrolides in management of patients with mild COVID-19. Scientific reports. 2021 08; 11(1):16361. doi: 10.1038/s41598-021-95900-z. [PMID: 34381155]
  • M Kovacheva-Slavova, H Valkov, T Angelov, R Tropcheva, B Vladimirov. Screening for Helicobacter pylori infection and Clarithromycin resistance using Real-Time Polymerase Chain Reaction. European review for medical and pharmacological sciences. 2021 08; 25(15):5042-5046. doi: 10.26355/eurrev_202108_26461. [PMID: 34355376]
  • Keisuke Nakase, Mayu Nakanishi-Yamasaki, Kanji Harada, Juri Koizumi, Tetsuya Yamada, Hideaki Ikoshi, Hidemasa Nakaminami, Norihisa Noguchi. Antimicrobial activity and additive effect of the modified Gingyo-san with antimicrobials against Helicobacter pylori. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2021 Jul; 27(7):957-961. doi: 10.1016/j.jiac.2021.02.008. [PMID: 33602640]
  • Mohamed Sharaf, Muhammad Arif, Sohaib Khan, Mohnad Abdalla, Samah Shabana, Zhe Chi, Chenguang Liu. Co-delivery of hesperidin and clarithromycin in a nanostructured lipid carrier for the eradication of Helicobacter pylori in vitro. Bioorganic chemistry. 2021 07; 112(?):104896. doi: 10.1016/j.bioorg.2021.104896. [PMID: 33901764]
  • Man Xie, Qing Li, Bei Zhang, Qun Zhang, Qiu-Ju Tian, Hong Liu, Yun-Jin Zang, Wei Rao. Preliminary single-center experience of Helicobacter pylori eradication among the liver transplant recipients. Helicobacter. 2021 Jun; 26(3):e12791. doi: 10.1111/hel.12791. [PMID: 33600067]
  • Sara Abolghasemi, Shahnaz Sali, Arad Mobasher Aghdam, Mohammad Amin Shahrbaf. Anti-tuberculosis Induced Stevens-Johnson Syndrome Due to Misdiagnosis of Mycobacterium Abscessus Urinary Tract Infection as Tuberculosis. Iranian journal of kidney diseases. 2021 May; 15(3):235-237. doi: NULL. [PMID: 33994384]
  • Ahmed Aljishi, Marwan Jabr Alwazzeh, Mar Kristjansson. Pneumonia due to Mycobacterium cosmeticum in a renal transplant recipient. BMJ case reports. 2021 Mar; 14(3):. doi: 10.1136/bcr-2020-234800. [PMID: 33653829]
  • Jianglin Peng, Jiahua Guo, Yuan Lei, Jiezhang Mo, Haotian Sun, Jinxi Song. Integrative analyses of transcriptomics and metabolomics in Raphidocelis subcapitata treated with clarithromycin. Chemosphere. 2021 Mar; 266(?):128933. doi: 10.1016/j.chemosphere.2020.128933. [PMID: 33223212]
  • Soyoung Lee, Yujin Lee, Andrew HyoungJin Kim, Sumin Yoon, Jieon Lee, Sang Chun Ji, Seo Hyun Yoon, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Joo-Youn Cho. Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects. Drug metabolism and pharmacokinetics. 2021 Feb; 36(?):100374. doi: 10.1016/j.dmpk.2020.12.001. [PMID: 33348239]
  • Xueping Huang, Yuan Liu, Zhihui Lin, Baihe Wu, Gaohui Nong, Yushan Chen, Yuping Lu, Xinhua Ji, Xiang Zhou, Biao Suo, Qiuzhao Chen, Jinqi Wei. Minimum inhibitory concentrations of commonly used antibiotics against Helicobacter Pylori: A multicenter study in South China. PloS one. 2021; 16(9):e0256225. doi: 10.1371/journal.pone.0256225. [PMID: 34473713]
  • Yao Chen, Hongxun Yuan, Hui Ye, Zongming Shi, Xin Deng, Xuezhi Zhang, Xikang Hou. Application of a semi-automatic, intensive follow-up for improving efficacy and adherence of Helicobacter pylori eradication therapy: A randomized controlled trial. MicrobiologyOpen. 2021 01; 10(1):e1172. doi: 10.1002/mbo3.1172. [PMID: 33650799]
  • Guoping Luo, Anqi Lin, Zhaoqiang Yang, Yujian Chen, Cuiying Mo. Computerized Tomography Image Feature under Convolutional Neural Network Algorithm Evaluated for Therapeutic Effect of Clarithromycin Combined with Salmeterol/Fluticasone on Chronic Obstructive Pulmonary Disease. Journal of healthcare engineering. 2021; 2021(?):8563181. doi: 10.1155/2021/8563181. [PMID: 34381586]
  • M A Gedikli, B Tuzun, A Aktas, K Sayin, H Ataseven. Are clarithromycin, azithromycin and their analogues effective in the treatment of COVID19?. Bratislavske lekarske listy. 2021; 122(2):101-110. doi: 10.4149/bll_2021_015. [PMID: 33502877]
  • Soonsil Hyun, Yoonhwa Choi, Doyeon Jo, Seolah Choo, Tae Woo Park, Su-Jin Park, Seoyeon Kim, Seonju Lee, Sohyun Park, Sun Mi Jin, Dae Hee Cheon, Wanki Yoo, Rekha Arya, Yong Pil Chong, Kyeong Kyu Kim, Yang Soo Kim, Yan Lee, Jaehoon Yu. Proline Hinged Amphipathic α-Helical Peptide Sensitizes Gram-Negative Bacteria to Various Gram-Positive Antibiotics. Journal of medicinal chemistry. 2020 12; 63(23):14937-14950. doi: 10.1021/acs.jmedchem.0c01506. [PMID: 33205989]
  • Shin-Ichiro Ogawa, Makiko Shimizu, Hiroshi Yamazaki. Modelled plasma concentrations of pemafibrate with co-administered typical cytochrome P450 inhibitors clopidogrel, fluconazole or clarithromycin predicted by physiologically based pharmacokinetic modelling in virtual populations. Xenobiotica; the fate of foreign compounds in biological systems. 2020 Dec; 50(12):1413-1422. doi: 10.1080/00498254.2020.1793030. [PMID: 32628085]
  • Melodi Yusibova, Henrik Hasman, Philip Thomas Lanken Conradsen Clausen, Frank Imkamp, Karoline Wagner, Leif Percival Andersen. CRHP Finder, a webtool for the detection of clarithromycin resistance in Helicobacter pylori from whole-genome sequencing data. Helicobacter. 2020 Dec; 25(6):e12752. doi: 10.1111/hel.12752. [PMID: 32844531]
  • Yao Chen, Qingyi Liu, Fulian Hu, Jizheng Ma. Identifying the best regimen for primary eradication of Helicobacter pylori: analysis of 240 cases. MicrobiologyOpen. 2020 11; 9(11):e1120. doi: 10.1002/mbo3.1120. [PMID: 33026166]
  • Eui Hyun Jung, Choong-Min Lee, Ji-Yeong Byeon, Hyo-Bin Shin, Kyung-Yul Oh, Chang-Keun Cho, Chang Woo Lim, Choon-Gon Jang, Seok-Yong Lee, Yun Jeong Lee. Relationship between plasma exposure of zolpidem and CYP2D6 genotype in healthy Korean subjects. Archives of pharmacal research. 2020 Sep; 43(9):976-981. doi: 10.1007/s12272-020-01250-1. [PMID: 32661920]
  • Iram Kaukab, Syed Nisar Hussain Shah, Zelal Jaber Kharaba, Manal Ali Buabeid, Yaseen Abd Alfoteih, Ghulam Murtaza. Effect of clarithromycin pre-treatment on the pharmacokinetics of metoclopramide after their simultaneous oral intake. Expert opinion on drug metabolism & toxicology. 2020 Aug; 16(8):735-740. doi: 10.1080/17425255.2020.1779699. [PMID: 32524862]
  • Bernardo Guevara, Asha Gupta Cogdill. Helicobacter pylori: A Review of Current Diagnostic and Management Strategies. Digestive diseases and sciences. 2020 07; 65(7):1917-1931. doi: 10.1007/s10620-020-06193-7. [PMID: 32170476]
  • Lorenzo Villa Zapata, Philip D Hansten, John R Horn, Richard D Boyce, Sheila Gephart, Vignesh Subbian, Andrew Romero, Daniel C Malone. Evidence of Clinically Meaningful Drug-Drug Interaction With Concomitant Use of Colchicine and Clarithromycin. Drug safety. 2020 07; 43(7):661-668. doi: 10.1007/s40264-020-00930-7. [PMID: 32274687]
  • Dalila Junqueira Alvarenga, Laira Maria Faria Matias, Lucas Martins Oliveira, Luiz Paulo Melchior de Oliveira Leão, Jamie Anthony Hawkes, Breno Vilas Boas Raimundo, Lívia de Figueiredo Diniz Castro, Marli Matiko Anraku de Campos, Fallon Dos Santos Siqueira, Thiago Dos Santos, Diogo Teixeira Carvalho. Exploring how structural changes to new Licarin A derivatives effects their bioactive properties against rapid growing mycobacteria and biofilm formation. Microbial pathogenesis. 2020 Jul; 144(?):104203. doi: 10.1016/j.micpath.2020.104203. [PMID: 32304794]
  • Maria M Posada, Bridget L Morse, P Kellie Turner, Palaniappan Kulanthaivel, Stephen D Hall, Gemma L Dickinson. Predicting Clinical Effects of CYP3A4 Modulators on Abemaciclib and Active Metabolites Exposure Using Physiologically Based Pharmacokinetic Modeling. Journal of clinical pharmacology. 2020 07; 60(7):915-930. doi: 10.1002/jcph.1584. [PMID: 32080863]
  • Se-Eun Kim, Azra Memon, Bae Yong Kim, Hyelin Jeon, Woon Kyu Lee, Se Chan Kang. Gastroprotective effect of phytoncide extract from Pinus koraiensis pinecone in Helicobacter pylori infection. Scientific reports. 2020 06; 10(1):9547. doi: 10.1038/s41598-020-66603-8. [PMID: 32533032]
  • José Millán-Oñate, William Millan, Luis Alfonso Mendoza, Carlos Guillermo Sánchez, Hugo Fernandez-Suarez, D Katterine Bonilla-Aldana, Alfonso J Rodríguez-Morales. Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin. Annals of clinical microbiology and antimicrobials. 2020 Apr; 19(1):16. doi: 10.1186/s12941-020-00358-y. [PMID: 32331519]
  • Mette Marie Hougaard Christensen, Maija Bruun Haastrup, Thomas Øhlenschlaeger, Peter Esbech, Sidsel Arnspang Pedersen, Ann-Cathrine Bach Dunvald, Tore Bjerregaard Stage, Daniel Pilsgaard Henriksen, Andreas James Thestrup Pedersen. Interaction potential between clarithromycin and individual statins-A systematic review. Basic & clinical pharmacology & toxicology. 2020 Apr; 126(4):307-317. doi: 10.1111/bcpt.13343. [PMID: 31628882]
  • Jakob Schroder, Janus Christian Jakobsen, Per Winkel, Jørgen Hilden, Gorm Boje Jensen, Ahmad Sajadieh, Anders Larsson, Johan Ärnlöv, Marina Harutyunyan, Julia S Johansen, Erik Kjøller, Christian Gluud, Jens Kastrup. Prognosis and Reclassification by YKL-40 in Stable Coronary Artery Disease. Journal of the American Heart Association. 2020 03; 9(5):e014634. doi: 10.1161/jaha.119.014634. [PMID: 32114892]
  • Raffaella Pascale, Giuliana Bianco, Donatella Coviello, Maria Cristina Lafiosca, Salvatore Masi, Ignazio M Mancini, Sabino A Bufo, Laura Scrano, Donatella Caniani. Validation of a liquid chromatography coupled with tandem mass spectrometry method for the determination of drugs in wastewater using a three-phase solvent system. Journal of separation science. 2020 Mar; 43(5):886-895. doi: 10.1002/jssc.201900509. [PMID: 31849166]
  • Jadson Soares Laudelino, Flávio Teles Farias Filho, André Falcão Pedrosa Costa, Vitorino Modesto Santos. Mycobacterium abscessus urinary tract infection: case report. Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia. 2020 Mar; 42(1):124-126. doi: 10.1590/2175-8239-jbn-2018-0260. [PMID: 31173040]
  • Jie Pan, Zhengchao Shi, Dingsai Lin, Ningmin Yang, Fei Meng, Lang Lin, Zhencheng Jin, Qingjie Zhou, Jiansheng Wu, Jianzhong Zhang, Youming Li. Is tailored therapy based on antibiotic susceptibility effective ? a multicenter, open-label, randomized trial. Frontiers of medicine. 2020 Feb; 14(1):43-50. doi: 10.1007/s11684-019-0706-8. [PMID: 31907860]
  • Yuko Higashi, Naoko Baba, Haruhito Yoshimine, Ikuyo Sakaguchi, Takuro Kanekura. Late-onset interstitial nephritis in a patient with drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. The Journal of dermatology. 2020 Feb; 47(2):174-177. doi: 10.1111/1346-8138.15175. [PMID: 31840853]
  • Jiahua Guo, Jianglin Peng, Yuan Lei, Mirella Kanerva, Qi Li, Jinxi Song, Jipu Guo, Haotian Sun. Comparison of oxidative stress induced by clarithromycin in two freshwater microalgae Raphidocelis subcapitata and Chlorella vulgaris. Aquatic toxicology (Amsterdam, Netherlands). 2020 Feb; 219(?):105376. doi: 10.1016/j.aquatox.2019.105376. [PMID: 31838304]
  • Tsutomu Nishida, Yuri Tsujii, Akino Okamoto, Ryo Tomita, Yu Higaki, Naoto Osugi, Aya Sugimoto, Kei Takahashi, Kaori Mukai, Dai Nakamatsu, Tokuhiro Matsubara, Shiro Hayashi, Masashi Yamamoto, Sachiko Nakajima, Koji Fukui, Masami Inada. A Triple-Drug Blister-Packaged Drug with Vonoprazan Improves First-Line Eradication of Helicobacter pylori in Elderly Patients: A Retrospective Propensity Score-Matched Cohort Study. Digestion. 2020; 101(5):608-614. doi: 10.1159/000501608. [PMID: 31288235]
  • Cristina Piras, Roberta Pintus, Dario Pruna, Angelica Dessì, Luigi Atzori, Vassilios Fanos. Pediatric Acute-onset Neuropsychiatric Syndrome and Mycoplasma Pneumoniae Infection: A Case Report Analysis with a Metabolomics Approach. Current pediatric reviews. 2020; 16(3):183-193. doi: 10.2174/1573396315666191022102925. [PMID: 31642785]
  • Ankita Saxena, Asish Kumar Mukhopadhyay, Shoma Paul Nandi. Helicobacter pylori: Perturbation and restoration of gut microbiome. Journal of biosciences. 2020; 45(?):. doi: 10.1007/s12038-020-00078-7. [PMID: 32975237]
  • Donald N Ngwa, Sanjay K Singh, Alok Agrawal. C-Reactive Protein-Based Strategy to Reduce Antibiotic Dosing for the Treatment of Pneumococcal Infection. Frontiers in immunology. 2020; 11(?):620784. doi: 10.3389/fimmu.2020.620784. [PMID: 33552084]
  • Daniel Martingano, Ashley Nguyen, Claudia Nkeih, Shailini Singh, Antonina Mitrofanova. Clarithromycin use for adjunct surgical prophylaxis before non-elective cesarean deliveries to adapt to azithromycin shortages in COVID-19 pandemic. PloS one. 2020; 15(12):e0244266. doi: 10.1371/journal.pone.0244266. [PMID: 33347510]
  • Inés Castro, Nicolas Fabre, Sandra Bourgeade-Delmas, Nathalie Saffon, Chloé Gandini, Michel Sauvain, Denis Castillo, Geneviève Bourdy, Valérie Jullian. Structural Characterization and Anti-infective Activity of 9,10-Seco-29-norcycloartane Glycosides Isolated from the Flowers of the Peruvian Medicinal Plant Cordia lutea. Journal of natural products. 2019 12; 82(12):3233-3241. doi: 10.1021/acs.jnatprod.9b00149. [PMID: 31800248]
  • Amr Shaaban Hanafy, Waseem M Seleem. Refractory Helicobacter pylori gastritis: The hidden predictors of resistance. Journal of global antimicrobial resistance. 2019 12; 19(?):194-200. doi: 10.1016/j.jgar.2019.05.015. [PMID: 31112805]
  • Choong-Min Lee, Eui Hyun Jung, Ji-Yeong Byeon, Se-Hyung Kim, Choon-Gon Jang, Yun Jeong Lee, Seok-Yong Lee. Effects of steady-state clarithromycin on the pharmacokinetics of zolpidem in healthy subjects. Archives of pharmacal research. 2019 Dec; 42(12):1101-1106. doi: 10.1007/s12272-019-01201-5. [PMID: 31820397]
  • Danijela Kötke, Juergen Gandrass, Zhiyong Xie, Ralf Ebinghaus. Prioritised pharmaceuticals in German estuaries and coastal waters: Occurrence and environmental risk assessment. Environmental pollution (Barking, Essex : 1987). 2019 Dec; 255(Pt 1):113161. doi: 10.1016/j.envpol.2019.113161. [PMID: 31541808]
  • Samira Garonzik, Wonkyung Byon, Elsa Myers, Xiodong Li, David Marchisin, Bindu Murthy. The Effects of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Volunteers: A Single-Sequence Crossover Study. American journal of cardiovascular drugs : drugs, devices, and other interventions. 2019 Dec; 19(6):561-567. doi: 10.1007/s40256-019-00348-2. [PMID: 31030414]
  • Kiyoshi Ashida, Youichirou Honda, Katsuyuki Sanada, Yukiko Takemura, Shigeru Sakamoto. The safety and effectiveness of vonoprazan-based Helicobacter pylori eradication therapy; a prospective post-marketing surveillance. Expert opinion on drug safety. 2019 Dec; 18(12):1255-1261. doi: 10.1080/14740338.2019.1676722. [PMID: 31646920]
  • Denise Türk, Nina Hanke, Sarah Wolf, Sebastian Frechen, Thomas Eissing, Thomas Wendl, Matthias Schwab, Thorsten Lehr. Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole. Clinical pharmacokinetics. 2019 12; 58(12):1595-1607. doi: 10.1007/s40262-019-00777-x. [PMID: 31129789]
  • Pedro Marques, Pierre-Yves Courand, Isabelle Gouin-Thibault, Valentina Zhygalina, Damien Bergerot, Joe-Elie Salem, Christian Funck-Brentano, Marie-Anne Loriot, Michel Azizi, Anne Blanchard. P-glycoprotein influences urinary excretion of aldosterone in healthy individuals. Journal of hypertension. 2019 11; 37(11):2225-2231. doi: 10.1097/hjh.0000000000002150. [PMID: 31157746]
  • Jun-Hyung Cho, Seong Ran Jeon, So-Young Jin, Suyeon Park. Analysis of factors associated with recovery of the serum pepsinogen ratio after Helicobacter pylori eradication: a long-term follow-up study in Korea. Scandinavian journal of gastroenterology. 2019 Nov; 54(11):1306-1314. doi: 10.1080/00365521.2019.1686058. [PMID: 31702966]
  • Stephanie Ortiz-Collazos, Paulo H S Picciani, Osvaldo N Oliveira, Andre S Pimentel, Karen J Edler. Influence of levofloxacin and clarithromycin on the structure of DPPC monolayers. Biochimica et biophysica acta. Biomembranes. 2019 10; 1861(10):182994. doi: 10.1016/j.bbamem.2019.05.016. [PMID: 31145899]
  • Bayew Tsega Abebe, Michael Weiss, Christiane Modess, Tarek Roustom, Tobias Tadken, Danilo Wegner, Ulrich Schwantes, Claudia Neumeister, Hans-Ulrich Schulz, Eberhard Scheuch, Werner Siegmund. Effects of the P-Glycoprotein Inhibitor Clarithromycin on the Pharmacokinetics of Intravenous and Oral Trospium Chloride: A 4-Way Crossover Drug-Drug Interaction Study in Healthy Subjects. Journal of clinical pharmacology. 2019 10; 59(10):1319-1330. doi: 10.1002/jcph.1421. [PMID: 30973998]
  • Lifeng Luo, Qiuyue Chen, Nana Wei, Yi Liu, Haibing He, Yu Zhang, Tian Yin, Jingxin Gou, Xing Tang. The modulation of drug-loading stability within lipid membranes via medium chain triglycerides incorporation. International journal of pharmaceutics. 2019 Jul; 566(?):371-382. doi: 10.1016/j.ijpharm.2019.06.003. [PMID: 31170477]
  • Francesco Miconi, Nicola Principi, Lorenzo Cassiani, Federica Celi, Roberta Crispoldi, Ada Russo, Susanna Esposito, Manuela Papini. A Cheek Nodule in a Child: Be Aware of Idiopathic Facial Aseptic Granuloma and Its Differential Diagnosis. International journal of environmental research and public health. 2019 07; 16(14):. doi: 10.3390/ijerph16142471. [PMID: 31336722]
  • Shachi Mehta, Vincent Aranzana-Climent, Blandine Rammaert, Nicolas Grégoire, Sandrine Marchand, William Couet, Julien M Buyck. Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus. Antimicrobial agents and chemotherapy. 2019 07; 63(7):. doi: 10.1128/aac.02651-18. [PMID: 31061149]
  • Arne Gessner, Jörg König, Martin F Fromm. Clinical Aspects of Transporter-Mediated Drug-Drug Interactions. Clinical pharmacology and therapeutics. 2019 06; 105(6):1386-1394. doi: 10.1002/cpt.1360. [PMID: 30648735]
  • Xue-Meng Li, Wei Lv, Si-Yang Guo, Ya-Xin Li, Bing-Zhi Fan, Mark Cushman, Fan-Sheng Kong, Jun Zhang, Jian-Hua Liang. Synthesis and structure-bactericidal activity relationships of non-ketolides: 9-Oxime clarithromycin 11,12-cyclic carbonate featured with three-to eight-atom-length spacers at 3-OH. European journal of medicinal chemistry. 2019 Jun; 171(?):235-254. doi: 10.1016/j.ejmech.2019.03.037. [PMID: 30925339]
  • Hyasinta Jaka, Andreas Mueller, Christa Kasang, Stephen E Mshana. Predictors of triple therapy treatment failure among H. pylori infected patients attending at a tertiary hospital in Northwest Tanzania: a prospective study. BMC infectious diseases. 2019 May; 19(1):447. doi: 10.1186/s12879-019-4085-1. [PMID: 31113384]
  • Toralph Ruge, Axel C Carlsson, Erik Kjøller, Jørgen Hilden, Hans Jørn Kolmos, Ahmad Sajadieh, Jens Kastrup, Gorm Boje Jensen, Anders Larsson, Christoph Nowak, Janus Christian Jakobsen, Per Winkel, Christian Gluud, Johan Ärnlöv. Circulating endostatin as a risk factor for cardiovascular events in patients with stable coronary heart disease: A CLARICOR trial sub-study. Atherosclerosis. 2019 05; 284(?):202-208. doi: 10.1016/j.atherosclerosis.2019.02.031. [PMID: 30959314]
  • Saeed Alborzi, Tahereh Poordast, Elham Askary, Gita Dorniani. Effects of clarithromycin on inflammatory markers and clinical manifestations in postsurgical follow-up of patients with endometriosis: a double-blinded randomized placebo-controlled clinical trial. Archives of gynecology and obstetrics. 2019 05; 299(5):1305-1312. doi: 10.1007/s00404-019-05057-4. [PMID: 30888478]
  • Pengyu Li, Xiaonan Chen, Yuanna Shen, Huatian Li, Yiqing Zou, Gang Yuan, Ping Hu, Haiyan Hu. Mucus penetration enhanced lipid polymer nanoparticles improve the eradication rate of Helicobacter pylori biofilm. Journal of controlled release : official journal of the Controlled Release Society. 2019 04; 300(?):52-63. doi: 10.1016/j.jconrel.2019.02.039. [PMID: 30825476]
  • Roberta Callus, Tiziana Felice, Deborah Balzan, Lara Delicata. Digoxin toxicity precipitated by Helicobacter pylori eradication therapy. British journal of hospital medicine (London, England : 2005). 2019 Apr; 80(4):228-229. doi: 10.12968/hmed.2019.80.4.228. [PMID: 30951424]
  • Run Tian, Rong Zhang, Misbah Uddin, Xianliang Qiao, Jingwen Chen, Gege Gu. Uptake and metabolism of clarithromycin and sulfadiazine in lettuce. Environmental pollution (Barking, Essex : 1987). 2019 Apr; 247(?):1134-1142. doi: 10.1016/j.envpol.2019.02.009. [PMID: 30823342]
  • Sheila E Crowe. Helicobacter pylori Infection. The New England journal of medicine. 2019 Mar; 380(12):1158-1165. doi: 10.1056/nejmcp1710945. [PMID: 30893536]
  • Xianli Xu, Xiaojie Lao, Chunlan Zhang, Cunwei Cao, Huarong Ding, Yu Pang, Qiuyue Ning, Jun Zou, Ning Zang, Diefei Hu, Maowei Chen. Chronic Mycobacterium avium skin and soft tissue infection complicated with scalp osteomyelitis possibly secondary to anti-interferon-γ autoantibody formation. BMC infectious diseases. 2019 Feb; 19(1):203. doi: 10.1186/s12879-019-3771-3. [PMID: 30819109]
  • Barbara Michalak, Jakub P Piwowarski, Sebastian Granica, Birgit Waltenberger, Atanas G Atanasov, Shafaat Y Khan, Johannes M Breuss, Pavel Uhrin, Barbara Żyżyńska-Granica, Anna Stojakowska, Hermann Stuppner, Anna K Kiss. Eupatoriopicrin Inhibits Pro-inflammatory Functions of Neutrophils via Suppression of IL-8 and TNF-alpha Production and p38 and ERK 1/2 MAP Kinases. Journal of natural products. 2019 02; 82(2):375-385. doi: 10.1021/acs.jnatprod.8b00939. [PMID: 30653318]
  • Xin Ma, Yuanyuan Jing, Yan Liu, Lisheng Yu. Effect of clarithromycin in von Hippel-Lindau syndrome: a case report. The Journal of international medical research. 2019 Feb; 47(2):973-981. doi: 10.1177/0300060518792368. [PMID: 30178691]
  • Dong-Min Yi, Tao-Tao Yang, Shuai-Heng Chao, Ya-Xin Li, Ying-Lei Zhou, Hai-Hui Zhang, Ling Lan, Yu-Wei Zhang, Xue-Mei Wang, Yan-Rui Zhang, Jian Li, Song-Ze Ding. Comparison the cost-efficacy of furazolidone-based versus clarithromycin-based quadruple therapy in initial treatment of Helicobacter pylori infection in a variable clarithromycin drug-resistant region, a single-center, prospective, randomized, open-label study. Medicine. 2019 Feb; 98(6):e14408. doi: 10.1097/md.0000000000014408. [PMID: 30732192]
  • Naoto Iwai, Takashi Okuda, Kohei Oka, Tasuku Hara, Yutaka Inada, Toshifumi Tsuji, Toshiyuki Komaki, Ken Inoue, Osamu Dohi, Hideyuki Konishi, Yuji Naito, Yoshito Itoh, Keizo Kagawa. Helicobacter pylori eradication increases the serum high density lipoprotein cholesterol level in the infected patients with chronic gastritis: A single-center observational study. PloS one. 2019; 14(8):e0221349. doi: 10.1371/journal.pone.0221349. [PMID: 31419266]