Mepyramine (BioDeep_00000002045)

   

human metabolite blood metabolite


代谢物信息卡片


N-[(4-Methoxyphenyl)methyl]-n,n-dimethyl-N-2-pyridinyl-1,2-ethanediamine

化学式: C17H23N3O (285.1841028)
中文名称: 美吡拉敏
谱图信息: 最多检出来源 Danio rerio(blood) 37.5%

分子结构信息

SMILES: CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2
InChI: InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3

描述信息

Mepyramine (also known as pyrilamine) is a first generation antihistamine, targeting the H1 receptor. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It is used in over-the-counter combination products for colds and menstrual symptoms.
D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AC - Substituted ethylene diamines
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists
C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3006
D018926 - Anti-Allergic Agents

同义名列表

17 个代谢物同义名

N-[(4-Methoxyphenyl)methyl]-n,n-dimethyl-N-2-pyridinyl-1,2-ethanediamine; N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine; N-(p-Methoxybenzyl)-n,n-dimethyl-N-(alpha-pyridyl)ethylenediamine; N,n-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine; N-(p-Methoxybenzyl)-n,n-dimethyl-N-(α-pyridyl)ethylenediamine; N-(p-Methoxybenzyl)-n,n-dimethyl-N-(a-pyridyl)ethylenediamine; Boots brand OF mepyramine maleate; Boots bite and sting relief; Maleate, mepyramine; Maleate, pyrilamine; Pyrilamine maleate; Mepyramine maleate; Pyranisamine; pyrilamine; Mepyramine; Anthisan; Kriptin



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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