METHAQUALONE (BioDeep_00000002035)

Main id: BioDeep_00000018024

 


代谢物信息卡片


METHAQUALONE

化学式: C16H14N2O (250.1106)
中文名称: 海米那
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC=CC=C1N2C(=NC3=CC=CC=C3C2=O)C
InChI: InChI=1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3

描述信息

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives
C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic

同义名列表

2 个代谢物同义名

METHAQUALONE; Methaqualone



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ALB, ANG, APOB, AXIN2, CAT, CENPJ, CYP2C19, CYP2D6, CYP3A4, PTP4A2, TAOK3
Peripheral membrane protein 1 TAOK3
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 4 APOB, CYP2C19, CYP2D6, CYP3A4
Nucleus 4 ALB, ANG, AXIN2, PTP4A2
cytosol 11 ACACA, ALB, ANG, APOB, AXIN2, CAT, CENPJ, GPT, LIPE, MTTP, PTP4A2
centrosome 3 ALB, AXIN2, CENPJ
Cell membrane 2 LIPE, TAOK3
Multi-pass membrane protein 1 CACNA1I
Synapse 1 CRH
Golgi apparatus 2 ALB, MTTP
Golgi membrane 1 INS
growth cone 1 ANG
neuronal cell body 2 ANG, APOB
smooth endoplasmic reticulum 1 APOB
Cytoplasm, cytosol 2 ACACA, LIPE
plasma membrane 6 APOB, AXIN2, CACNA1I, CYP2C19, PTP4A2, TAOK3
Membrane 5 CACNA1I, CAT, CYP2D6, CYP3A4, LIPE
basolateral plasma membrane 1 MTTP
caveola 1 LIPE
extracellular exosome 5 ALB, APOB, CAT, GPT, LYZ
endoplasmic reticulum 3 ALB, CYP2D6, MTTP
extracellular space 6 ALB, ANG, APOB, CRH, INS, LYZ
lysosomal lumen 1 APOB
mitochondrion 3 ACACA, CAT, CYP2D6
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 5 APOB, CAT, CYP2C19, CYP2D6, CYP3A4
Microsome membrane 2 CYP2D6, CYP3A4
Secreted 5 ALB, ANG, APOB, CRH, INS
extracellular region 7 ALB, ANG, APOB, CAT, CRH, INS, LYZ
Single-pass membrane protein 1 CYP2D6
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 CENPJ
varicosity 1 CRH
chylomicron 1 APOB
low-density lipoprotein particle 1 APOB
very-low-density lipoprotein particle 1 APOB
actin cytoskeleton 2 ACACA, ANG
neuronal dense core vesicle lumen 1 CRH
perikaryon 1 CRH
beta-catenin destruction complex 1 AXIN2
nucleolus 1 ANG
Early endosome 2 APOB, PTP4A2
vesicle 1 MTTP
focal adhesion 1 CAT
microtubule 1 CENPJ
Peroxisome 1 CAT
basement membrane 1 ANG
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
receptor complex 1 MTTP
ciliary basal body 2 ALB, CENPJ
Chromosome 1 ANG
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 1 CENPJ
centriole 2 ALB, CENPJ
brush border membrane 1 MTTP
Nucleus, nucleolus 1 ANG
spindle pole 1 ALB
blood microparticle 1 ALB
microvillus membrane 1 MTTP
fibrillar center 1 ACACA
endosome lumen 2 APOB, INS
Lipid droplet 2 APOB, LIPE
Membrane, caveola 1 LIPE
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, APOB, INS, MTTP
platelet alpha granule lumen 1 ALB
voltage-gated calcium channel complex 1 CACNA1I
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
procentriole replication complex 1 CENPJ
endocytic vesicle 1 ANG
transport vesicle 1 INS
azurophil granule lumen 1 LYZ
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
endoplasmic reticulum exit site 1 APOB
clathrin-coated endocytic vesicle membrane 1 APOB
endocytic vesicle lumen 1 APOB
chylomicron remnant 1 APOB
intermediate-density lipoprotein particle 1 APOB
angiogenin-PRI complex 1 ANG
catalase complex 1 CAT
mature chylomicron 1 APOB
ciliary transition fiber 1 ALB
gamma-tubulin small complex 1 CENPJ


文献列表

  • Xinlv Chen, Shuqin Liu, Ruifen Jiang, Tiangang Luan, Gangfeng Ouyang. Rapid detection and speciation of illicit drugs via a thin-film microextraction approach for wastewater-based epidemiology study. The Science of the total environment. 2022 Oct; 842(?):156888. doi: 10.1016/j.scitotenv.2022.156888. [PMID: 35753476]
  • Tara Carney, Jennifer A Rooney, Nandi Niemand, Bronwyn Myers, Danie Theron, Robin Wood, Laura F White, Christina S Meade, Novel N Chegou, Elizabeth Ragan, Gerhard Walzl, Robert Horsburgh, Robin M Warren, Karen R Jacobson. Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL): A cross-sectional observational study protocol using respondent driven sampling. PloS one. 2022; 17(2):e0262440. doi: 10.1371/journal.pone.0262440. [PMID: 35167586]
  • Katrin Romanek, Helena Fels, Torsten Dame, Gisela Skopp, Frank Musshoff, Hans Eiglmeier, Florian Eyer. Return of the Quaaludes? Prolonged agitated delirium after intentional ingestion of the methaqualone analog SL-164 - a case report. Substance abuse. 2021; 42(4):503-505. doi: 10.1080/08897077.2021.1903648. [PMID: 33760714]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
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