Trenbolone (BioDeep_00000001963)

   


代谢物信息卡片


(8S,13S,14S,17R)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one

化学式: C18H22O2 (270.162)
中文名称: 群勃龙, 17α-群勃龙
谱图信息: 最多检出来源 Homo sapiens(plant) 21.69%

分子结构信息

SMILES: CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2O
InChI: InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h8-10,15-17,20H,2-7H2,1H3

描述信息

A 3-oxo-Delta(4) steroid that is estra-4,9,11-triene carrying an oxo group at position 3 and a hydroxy group at position 17beta. It is a synthetic anabolic steroid used for muscle growth in livestock.
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
CONFIDENCE standard compound; INTERNAL_ID 2824
CONFIDENCE standard compound; INTERNAL_ID 8746
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8822; ORIGINAL_PRECURSOR_SCAN_NO 8819
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8842; ORIGINAL_PRECURSOR_SCAN_NO 8840
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4804; ORIGINAL_PRECURSOR_SCAN_NO 4803
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8845; ORIGINAL_PRECURSOR_SCAN_NO 8842
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8903; ORIGINAL_PRECURSOR_SCAN_NO 8901
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4774; ORIGINAL_PRECURSOR_SCAN_NO 4772
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4796; ORIGINAL_PRECURSOR_SCAN_NO 4794
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4817; ORIGINAL_PRECURSOR_SCAN_NO 4815
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8823; ORIGINAL_PRECURSOR_SCAN_NO 8820
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4834; ORIGINAL_PRECURSOR_SCAN_NO 4832
CONFIDENCE standard compound; INTERNAL_ID 787; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8866; ORIGINAL_PRECURSOR_SCAN_NO 8863

同义名列表

5 个代谢物同义名

Trenbolone; (8S,13S,14S,17R)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one; 17beta-Trenbolone; Trienbolone; Trenbolone



数据库引用编号

37 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AR, CACNA1A, CASP3, DMRT1, ESR1, MITF, MTPN, NPPA, NR3C1, TYR
Peripheral membrane protein 1 ESR1
Endoplasmic reticulum membrane 1 CYP19A1
Nucleus 9 AR, CACNA1A, CASP3, DMRT1, ESR1, FOXL2, MITF, MTPN, NR3C1
cytosol 6 AR, CASP3, ESR1, MITF, MTPN, NR3C1
centrosome 1 NR3C1
nucleoplasm 6 AR, CASP3, ESR1, FOXL2, MITF, NR3C1
Cell membrane 2 CACNA1A, ESR1
Cytoplasmic side 1 ESR1
Multi-pass membrane protein 2 CACNA1A, CYP19A1
Synapse 3 CACNA1A, HCRT, NR3C1
glutamatergic synapse 1 CASP3
Golgi apparatus 2 ATRN, ESR1
Golgi membrane 1 INS
lysosomal membrane 1 MITF
neuronal cell body 2 CACNA1A, CASP3
postsynapse 1 HCRT
synaptic vesicle 1 HCRT
Lysosome 1 TYR
plasma membrane 4 AR, ATRN, CACNA1A, ESR1
Membrane 5 AR, CACNA1A, CYP19A1, ESR1, NR3C1
axon 1 MTPN
extracellular exosome 1 ATRN
Lysosome membrane 1 MITF
endoplasmic reticulum 1 CYP19A1
extracellular space 8 AMH, ATRN, BMP7, GNRH1, IGF1, INS, MSTN, NPPA
perinuclear region of cytoplasm 3 HCRT, MTPN, TYR
mitochondrion 1 NR3C1
protein-containing complex 5 AR, ESR1, MITF, NPPA, NR3C1
intracellular membrane-bounded organelle 1 TYR
Microsome membrane 1 CYP19A1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 ATRN, TYR
Secreted 6 AMH, BMP7, IGF1, INS, MSTN, NPPA
extracellular region 7 AMH, BMP7, GNRH1, HCRT, IGF1, INS, NPPA
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 1 NR3C1
transcription regulator complex 1 ESR1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 NR3C1
neuronal dense core vesicle lumen 1 HCRT
perikaryon 1 NPPA
cytoplasmic vesicle 1 HCRT
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
vesicle 1 BMP7
Cytoplasm, perinuclear region 1 MTPN
Cytoplasm, cytoskeleton, spindle 1 NR3C1
spindle 1 NR3C1
collagen-containing extracellular matrix 2 BMP7, NPPA
nuclear speck 2 AR, NR3C1
chromatin 6 AR, DMRT1, ESR1, FOXL2, MITF, NR3C1
cell projection 2 CACNA1A, NPPA
Chromosome 1 NR3C1
Flemming body 1 FOXL2
[Isoform 3]: Secreted 1 ATRN
endosome lumen 1 INS
monoatomic ion channel complex 1 CACNA1A
female germ cell nucleus 1 DMRT1
Nucleus, nucleoplasm 1 NR3C1
Melanosome 1 TYR
euchromatin 1 ESR1
exocytic vesicle 1 IGF1
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
platelet alpha granule lumen 1 IGF1
voltage-gated calcium channel complex 1 CACNA1A
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
[Isoform 1]: Nucleus 1 ESR1
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 1 ATRN
Rough endoplasmic reticulum 1 HCRT
[Isoform Alpha]: Cytoplasm 1 NR3C1
[Long-acting natriuretic peptide]: Secreted 1 NPPA
[Vessel dilator]: Secreted 1 NPPA
[Kaliuretic peptide]: Secreted 1 NPPA
[Urodilatin]: Secreted 1 NPPA
[Atrial natriuretic peptide]: Secreted 1 NPPA
[Atriopeptin-3]: Secreted 1 NPPA
[Isoform Beta]: Nucleus 1 NR3C1
[Isoform Alpha-B]: Nucleus 1 NR3C1
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
F-actin capping protein complex 1 MTPN


文献列表

  • Hua Tian, Rui Liu, Suqiu Zhang, Shuhui Wei, Wei Wang, Shaoguo Ru. 17β-Trenbolone binds to androgen receptor, decreases number of primordial germ cells, modulates expression of genes related to sexual differentiation, and affects sexual differentiation in zebrafish (Danio rerio). The Science of the total environment. 2022 Feb; 806(Pt 4):150959. doi: 10.1016/j.scitotenv.2021.150959. [PMID: 34662611]
  • Shaozhi Zhang, Xizeng Feng. Effect of 17β-trenbolone exposure during adolescence on the circadian rhythm in male mice. Chemosphere. 2022 Feb; 288(Pt 1):132496. doi: 10.1016/j.chemosphere.2021.132496. [PMID: 34627821]
  • Sabrina Liesenfeld, Panagiotis Steliopoulos, Svenja Wenig, Vera Gottstein, Gerd Hamscher. Comprehensive LC-HRMS metabolomics analyses for the estimation of environmental inputs of altrenogest in pig breeding. Chemosphere. 2022 Jan; 287(Pt 3):132353. doi: 10.1016/j.chemosphere.2021.132353. [PMID: 34826959]
  • Rafael Dal Forno Gianluppi, Matheus Schardong Lucca, Monike Quirino, Ana Paula Gonçalves Mellagi, Rafael da Rosa Ulguim, Fernando Pandolfo Bortolozzo. Altrenogest treatment during the last week of lactation on ovarian traits and subsequent reproductive performance of primiparous and multiparous sows. Theriogenology. 2021 Dec; 176(?):122-127. doi: 10.1016/j.theriogenology.2021.09.027. [PMID: 34601236]
  • Yanyan Li, Haifeng Yang, Liangyou Xia, Shuang Wang, Shijin Bu. Comparative pharmacokinetic study of two kinds of altrenogest oral solutions for sows. Animal biotechnology. 2021 Aug; 32(4):479-485. doi: 10.1080/10495398.2020.1723608. [PMID: 32180500]
  • Yanyan Li, Haifeng Yang, Shulei Qiu, Shuang Wang, Liangyou Xia, Shijin Bu. Investigations on residual elimination of altrenogest oral solution in pigs and the withdrawal time. Animal biotechnology. 2021 Jun; 32(3):310-317. doi: 10.1080/10495398.2019.1689989. [PMID: 31814507]
  • Ashley Gillon, Emmie N M Ho, George H M Chan, Alexia Kauff, Gillian Hughes, Rachel A Lund, Zoe Ashley, Terence S M Wan, Alison K Heather. Unravelling androgens in sport: Altrenogest shows strong activation of the androgen receptor in a mammalian cell bioassay. Drug testing and analysis. 2021 Mar; 13(3):523-528. doi: 10.1002/dta.2941. [PMID: 33037724]
  • J K Challis, S Sura, J Cantin, A W Curtis, K M Shade, T A McAllister, P D Jones, J P Giesy, F J Larney. Ractopamine and Other Growth-Promoting Compounds in Beef Cattle Operations: Fate and Transport in Feedlot Pens and Adjacent Environments. Environmental science & technology. 2021 02; 55(3):1730-1739. doi: 10.1021/acs.est.0c06450. [PMID: 33450151]
  • C C Reichhardt, A Ahmadpour, R G Christensen, N E Ineck, G K Murdoch, K J Thornton. Understanding the influence of trenbolone acetate and polyamines on proliferation of bovine satellite cells. Domestic animal endocrinology. 2021 01; 74(?):106479. doi: 10.1016/j.domaniend.2020.106479. [PMID: 32615508]
  • Ruoxin Jia, Xiaoyu Chen, Zhiwei Zhu, Jing Huang, Fuxian Yu, Liang Zhang, Atsuo Ogura, Jianzhi Pan. Improving ovulation in gilts using anti-inhibin serum treatment combined with fixed-time artificial insemination. Reproduction in domestic animals = Zuchthygiene. 2021 Jan; 56(1):112-119. doi: 10.1111/rda.13854. [PMID: 33152153]
  • Gerald T Ankley, Brett R Blackwell, Jenna E Cavallin, Jon A Doering, David J Feifarek, Kathleen M Jensen, Michael D Kahl, Carlie A LaLone, Shane T Poole, Eric C Randolph, Travis W Saari, Daniel L Villeneuve. Adverse Outcome Pathway Network-Based Assessment of the Interactive Effects of an Androgen Receptor Agonist and an Aromatase Inhibitor on Fish Endocrine Function. Environmental toxicology and chemistry. 2020 04; 39(4):913-922. doi: 10.1002/etc.4668. [PMID: 31965587]
  • Hongzhi Xiao, Pan Sun, Feifei Sun, Jicheng Qiu, Jie Wang, Jianzhong Wang, Yalong Lin, Xiaohui Gong, Lu Zhang, Suxia Zhang, Xingyuan Cao. Pharmacokinetics of altrenogest in gilts. Journal of veterinary pharmacology and therapeutics. 2019 Nov; 42(6):660-664. doi: 10.1111/jvp.12755. [PMID: 31222770]
  • Paweena Thuwanut, Janine L Brown, Pierre Comizzoli, Adrienne E Crosier. Responsiveness of the cheetah (Acinonyx jubatus) ovary to exogenous gonadotropins after preemptive oral progestin treatment. Theriogenology. 2019 Oct; 138(?):39-46. doi: 10.1016/j.theriogenology.2019.07.001. [PMID: 31284220]
  • Katie L Bidne, Matthew R Romoser, Jason W Ross, Lance H Baumgard, Aileen F Keating. Heat stress during the luteal phase decreases luteal size but does not affect circulating progesterone in gilts1. Journal of animal science. 2019 Oct; 97(10):4314-4322. doi: 10.1093/jas/skz251. [PMID: 31372640]
  • Sabrina Lehmann, Andreas Thomas, Karl-Heinz Schiwy-Bochat, Hans Geyer, Mario Thevis, Frank Glenewinkel, Markus Alexander Rothschild, Hilke Andresen-Streichert, Martin Juebner. Death after misuse of anabolic substances (clenbuterol, stanozolol and metandienone). Forensic science international. 2019 Oct; 303(?):109925. doi: 10.1016/j.forsciint.2019.109925. [PMID: 31499423]
  • Katelyn E Ellis, R McAlister Council-Troche, Karen A Von Dollen, Theresa M Beachler, C Scott Bailey, Jennifer L Davis, Sara K Lyle. Pharmacokinetics of Intrarectal Altrenogest in Horses. Journal of equine veterinary science. 2019 01; 72(?):41-46. doi: 10.1016/j.jevs.2018.10.001. [PMID: 30929782]
  • Vitória Müller, Bruna R Curcio, Ramiro E Toribio, Lorena S Feijó, Luciana A Borba, Igor F Canisso, Carlos E W Nogueira. Cortisol, progesterone, 17αOHprogesterone, and pregnenolone in foals born from mare's hormone-treated for experimentally induced ascending placentitis. Theriogenology. 2019 Jan; 123(?):139-144. doi: 10.1016/j.theriogenology.2018.06.024. [PMID: 30308389]
  • Katie L Bidne, Sara S Kvidera, Jason W Ross, Lance H Baumgard, Aileen F Keating. Impact of repeated lipopolysaccharide administration on ovarian signaling during the follicular phase of the estrous cycle in post-pubertal pigs. Journal of animal science. 2018 Sep; 96(9):3622-3634. doi: 10.1093/jas/sky226. [PMID: 29982469]
  • Zachary K Smith, Alex J Thompson, John P Hutcheson, Wade T Nichols, Bradley J Johnson. Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers. Journal of animal science. 2018 May; 96(5):1704-1723. doi: 10.1093/jas/sky095. [PMID: 29534183]
  • Francesca Lega, Roberto Angeletti, Roberto Stella, Lorenzo Rigoni, Giancarlo Biancotto, Danilo Giusepponi, Simone Moretti, Giorgio Saluti, Roberta Galarini. Abuse of anabolic agents in beef cattle: Could bile be a possible alternative matrix?. Food chemistry. 2017 Aug; 229(?):188-197. doi: 10.1016/j.foodchem.2017.02.069. [PMID: 28372163]
  • Natalie K Karouna-Renier, Yu Chen, Paula F P Henry, Catherine M Maddox, Daniel T Sprague. Effects on Circulating Steroid Hormones and Gene Expression along the Hypothalamus-Pituitary-Gonadal Axis in Adult Japanese Quail Exposed to 17β-Trenbolone across Multiple Generations. Toxicological sciences : an official journal of the Society of Toxicology. 2017 05; 157(1):62-73. doi: 10.1093/toxsci/kfx016. [PMID: 28108667]
  • Joseph A Robinson, Qingli Ma, Jane P Staveley, Walter J Smolenski. Sorption and desorption of 17α-trenbolone and trendione on five soils. Environmental toxicology and chemistry. 2017 03; 36(3):613-620. doi: 10.1002/etc.3711. [PMID: 27958649]
  • Joseph A Robinson, Qingli Ma, Jane P Staveley, Walter J Smolenski, Jon Ericson. Degradation and transformation of 17α-estradiol in water-sediment systems under controlled aerobic and anaerobic conditions. Environmental toxicology and chemistry. 2017 03; 36(3):621-629. doi: 10.1002/etc.3383. [PMID: 26801177]
  • Joseph A Robinson, Qingli Ma, Jane P Staveley, Walter J Smolenski, Jon Ericson. Degradation and transformation of 17α-trenbolone in aerobic water-sediment systems. Environmental toxicology and chemistry. 2017 03; 36(3):630-635. doi: 10.1002/etc.3381. [PMID: 26800846]
  • A J Ziecik, J Klos, E Przygrodzka, R Milewski, B Jana. Aberrant effects of altrenogest and exposure to exogenous gonadotropins on follicular cysts appearance in gilts. Theriogenology. 2017 Feb; 89(?):250-254. doi: 10.1016/j.theriogenology.2016.10.028. [PMID: 28043359]
  • Daniel L Villeneuve, Kathleen M Jensen, Jenna E Cavallin, Elizabeth J Durhan, Natàlia Garcia-Reyero, Michael D Kahl, Richard L Leino, Elizabeth A Makynen, Leah C Wehmas, Edward J Perkins, Gerald T Ankley. Effects of the antimicrobial contaminant triclocarban, and co-exposure with the androgen 17β-trenbolone, on reproductive function and ovarian transcriptome of the fathead minnow (Pimephales promelas). Environmental toxicology and chemistry. 2017 01; 36(1):231-242. doi: 10.1002/etc.3531. [PMID: 27312088]
  • Claudia Zanardello, Katia Capello, Roberto Stella, Giancarlo Biancotto, Marta Vascellari. Semiquantitative immunohistochemical detection of progesterone receptors in male accessory sex glands as a screening assay for anabolic steroid use in bulls. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 2017 Jan; 29(1):35-40. doi: 10.1177/1040638716681047. [PMID: 28074716]
  • Satomi Mizukami-Murata, Katsuyuki Kishi-Kadota, Takashi Nishida. 17β-Trenbolone exposure programs metabolic dysfunction in larval medaka. Environmental toxicology. 2016 Nov; 31(11):1539-1551. doi: 10.1002/tox.22158. [PMID: 26040664]
  • Louisa B Harding, Irvin R Schultz, Denis A M da Silva, Gina M Ylitalo, Dave Ragsdale, Stephanie I Harris, Stephanie Bailey, Barry V Pepich, Penny Swanson. Wastewater treatment plant effluent alters pituitary gland gonadotropin mRNA levels in juvenile coho salmon (Oncorhynchus kisutch). Aquatic toxicology (Amsterdam, Netherlands). 2016 Sep; 178(?):118-31. doi: 10.1016/j.aquatox.2016.07.013. [PMID: 27475653]
  • F F McConaghy, L A Green, S Colgan, L H Morris. Studies of the pharmacokinetic profile, in vivo efficacy and safety of injectable altrenogest for the suppression of oestrus in mares. Australian veterinary journal. 2016 Jul; 94(7):248-55. doi: 10.1111/avj.12459. [PMID: 27349885]
  • Christine Akre, Masahiro Mizuno. A screening and determinative method for the analysis of natural and synthetic steroids, stilbenes and resorcyclic acid lactones in bovine urine. Drug testing and analysis. 2016 May; 8(5-6):448-57. doi: 10.1002/dta.2012. [PMID: 27443199]
  • Daniel G Donner, Grace E Elliott, Belinda R Beck, Andrew C Bulmer, Alfred K Lam, John P Headrick, Eugene F Du Toit. Trenbolone Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic Syndrome. Endocrinology. 2016 Jan; 157(1):368-81. doi: 10.1210/en.2015-1603. [PMID: 26584015]
  • Karen H Watanabe, Michael Mayo, Kathleen M Jensen, Daniel L Villeneuve, Gerald T Ankley, Edward J Perkins. Predicting Fecundity of Fathead Minnows (Pimephales promelas) Exposed to Endocrine-Disrupting Chemicals Using a MATLAB®-Based Model of Oocyte Growth Dynamics. PloS one. 2016; 11(1):e0146594. doi: 10.1371/journal.pone.0146594. [PMID: 26756814]
  • Dudu Demir, Nahit Gencer, Oktay Arslan. An alternative purification method for human serum paraoxonase 1 and its interactions with anabolic compounds. Journal of enzyme inhibition and medicinal chemistry. 2016; 31(2):247-52. doi: 10.3109/14756366.2015.1018242. [PMID: 25792501]
  • Sam Bircher, Marcella L Card, Guangshu Zhai, Yu-Ping Chin, Jerald L Schnoor. Sorption, uptake, and biotransformation of 17β-estradiol, 17α-ethinylestradiol, zeranol, and trenbolone acetate by hybrid poplar. Environmental toxicology and chemistry. 2015 Dec; 34(12):2906-13. doi: 10.1002/etc.3166. [PMID: 26184466]
  • Brett R Blackwell, Bradley J Johnson, Michael D Buser, George P Cobb, Philip N Smith. Transformation kinetics of trenbolone acetate metabolites and estrogens in urine and feces of implanted steers. Chemosphere. 2015 Nov; 138(?):901-7. doi: 10.1016/j.chemosphere.2014.10.091. [PMID: 25550108]
  • Tatiane Micheletti, Janine L Brown, Susan L Walker, Zalmir S Cubas, Priscila V Furtado, Sarah B Putman, Wanderlei de Moraes, Marcos J de Oliveira, Claudio A de Oliveira, Nei Moreira. The use of altrenogest to avoid hyperestrogenism after eCG-hCG ovulation induction in southern tigrina (Leopardus guttulus). Theriogenology. 2015 Sep; 84(4):575-82. doi: 10.1016/j.theriogenology.2015.04.015. [PMID: 26001599]
  • Sophie Massart, Baptiste Redivo, Enora Flamion, S N M Mandiki, Elodie Falisse, Sylvain Milla, Patrick Kestemont. The trenbolone acetate affects the immune system in rainbow trout, Oncorhynchus mykiss. Aquatic toxicology (Amsterdam, Netherlands). 2015 Jun; 163(?):109-20. doi: 10.1016/j.aquatox.2015.04.007. [PMID: 25889087]
  • Maxim A Yunin, Pavel S Metalnikov, Alexander A Komarov, Alexander N Panin. Development of a rapid method for the analysis of trenbolone, nortestosterone, and zeranol in bovine liver using liquid chromatography tandem mass spectrometry. Analytical and bioanalytical chemistry. 2015 Jun; 407(15):4363-71. doi: 10.1007/s00216-014-8346-y. [PMID: 25450054]
  • Daniel G Donner, Belinda R Beck, Andrew C Bulmer, Alfred K Lam, Eugene F Du Toit. Improvements in body composition, cardiometabolic risk factors and insulin sensitivity with trenbolone in normogonadic rats. Steroids. 2015 Feb; 94(?):60-9. doi: 10.1016/j.steroids.2014.12.017. [PMID: 25554582]
  • Brett R Blackwell, Tyson R Brown, Paul R Broadway, Michael D Buser, J Chance Brooks, Bradley J Johnson, George P Cobb, Philip N Smith. Characterization of trenbolone acetate and estradiol metabolite excretion profiles in implanted steers. Environmental toxicology and chemistry. 2014 Dec; 33(12):2850-8. doi: 10.1002/etc.2757. [PMID: 25244153]
  • S L Parr, T R Brown, F R B Ribeiro, K Y Chung, J P Hutcheson, B R Blackwell, P N Smith, B J Johnson. Biological responses of beef steers to steroidal implants and zilpaterol hydrochloride. Journal of animal science. 2014 Aug; 92(8):3348-63. doi: 10.2527/jas.2013-7221. [PMID: 24987078]
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