ETHAMOXYTRIPHETOL (BioDeep_00001876797)
Main id: BioDeep_00000010006
代谢物信息卡片
化学式: C27H33NO3 (419.246)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN(CC)CCOC1=CC=C(C=C1)C(CC2=CC=C(C=C2)OC)(C3=CC=CC=C3)O
InChI: InChI=1S/C27H33NO3/c1-4-28(5-2)19-20-31-26-17-13-24(14-18-26)27(29,23-9-7-6-8-10-23)21-22-11-15-25(30-3)16-12-22/h6-18,29H,4-5,19-21H2,1-3H3
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists
同义名列表
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:34748
- KEGG: C14596
- PubChem: 6222
- ChEMBL: CHEMBL47647
- MeSH: Ethamoxytriphetol
- CAS: 67-98-1
- PubChem: 17395596
- NIKKAJI: J4.855K
- KNApSAcK: 34748
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2005 Jul; 46(1):e11-4. doi:
10.1053/j.ajkd.2005.03.009. [PMID: 15983949] - L Kim, Y S Weems, P J Bridges, B R LeaMaster, L Ching, D L Vincent, C W Weems. Effects of indomethacin, luteinizing hormone (LH), prostaglandin E2 (PGE2), trilostane, mifepristone, ethamoxytriphetol (MER-25) on secretion of prostaglandin E (PGE), prostaglandin F2alpha (PGF2alpha) and progesterone by ovine corpora lutea of pregnancy or the estrous cycle.
Prostaglandins & other lipid mediators.
2001 Mar; 63(4):189-203. doi:
10.1016/s0090-6980(01)00097-1. [PMID: 11305696] - R B Billiar, R Rohan, M C Henson, P Smith, J Babischkin. Regulation of immunoreactive inhibin patterns in baboon pregnancy: maternal, placental, and fetal considerations.
The Journal of clinical endocrinology and metabolism.
1992 Nov; 75(5):1345-51. doi:
10.1210/jcem.75.5.1430097. [PMID: 1430097] - J S Babischkin, G J Pepe, E D Albrecht. Regulation of progesterone biosynthesis by estrogen during baboon pregnancy: placental mitochondrial cholesterol side-chain cleavage activity in antiestrogen (ethamoxytriphetol, MER-25)-treated baboons.
Endocrinology.
1989 Apr; 124(4):1638-45. doi:
10.1210/endo-124-4-1638. [PMID: 2924716] - M C Henson, J S Babischkin, G J Pepe, E D Albrecht. Effect of the antiestrogen ethamoxytriphetol (MER-25) on placental low density lipoprotein uptake and degradation in baboons.
Endocrinology.
1988 May; 122(5):2019-26. doi:
10.1210/endo-122-5-2019. [PMID: 3359975] - M C Henson, G J Pepe, E D Albrecht. Transuterofetoplacental conversion of pregnenolone to progesterone in antiestrogen-treated baboons.
Endocrinology.
1987 Oct; 121(4):1265-71. doi:
10.1210/endo-121-4-1265. [PMID: 3653027] - D M Wunsch, L D Anderson, G J Pepe, E D Albrecht. Regulation of progesterone formation by human placental cells in culture.
Endocrinology.
1986 Sep; 119(3):998-1003. doi:
10.1210/endo-119-3-998. [PMID: 2942394] - V D Castracane, J W Goldzieher. The relationship of estrogen to placental steroidogenesis in the baboon.
The Journal of clinical endocrinology and metabolism.
1986 Jun; 62(6):1163-6. doi:
10.1210/jcem-62-6-1163. [PMID: 3700583] - E D Albrecht, G J Pepe. Effect of the antiestrogen ethamoxytriphetol (MER-25) and luteectomy on serum progesterone concentrations in pregnant baboons.
Endocrinology.
1984 Nov; 115(5):1717-21. doi:
10.1210/endo-115-5-1717. [PMID: 6489260] - E D Albrecht, G J Pepe. Source and regulation of 17 alpha-hydroxyprogesterone during baboon pregnancy.
Biology of reproduction.
1984 Oct; 31(3):471-9. doi:
10.1095/biolreprod31.3.471. [PMID: 6487691] - D R Mann, M S Blank, R Sridaran, V D Castracane, C Eldridge, D C Collins. Influence of anti-oestrogens on gonadotrophin secretion in control and ACTH-infused immature rats.
Acta endocrinologica.
1984 Mar; 105(3):308-13. doi:
10.1530/acta.0.1050308. [PMID: 6322494] - V D Castracane, T J Kuehl, J W Goldzieher. The effect of estrogen antagonism on progesterone production in early pregnancy in the baboon (Papio cynocephalus).
American journal of obstetrics and gynecology.
1983 Mar; 145(6):725-9. doi:
10.1016/0002-9378(83)90580-x. [PMID: 6829661] - P Södersten, P Eneroth. Neonatal treatment with antioestrogen increases the diurnal rhythmicity in the sexual behaviour of adult male rats.
The Journal of endocrinology.
1980 May; 85(2):331-9. doi:
10.1677/joe.0.0850331. [PMID: 7190600] - E D Albrecht. A role for estrogen in progesterone production during baboon pregnancy.
American journal of obstetrics and gynecology.
1980 Mar; 136(5):569-74. doi:
10.1016/0002-9378(80)91004-2. [PMID: 6766669] - R N Kurl, I D Morris. Differential depletion of cytoplasmic high affinity oestrogen receptors after the in vivo administration of the antioestrogens, clomiphene, MER-25 and tamoxifen.
British journal of pharmacology.
1978 Apr; 62(4):487-93. doi:
10.1111/j.1476-5381.1978.tb07752.x. [PMID: 656695] - P Södersten. Effects of anti-oestrogen treatment of neonatal male rats on lordosis behaviour and mounting behaviour in the adult.
The Journal of endocrinology.
1978 Feb; 76(2):241-9. doi:
10.1677/joe.0.0760241. [PMID: 627818] - K KOWALEWSKI. Lipid pattern in cockerels treated with oestradiol and MER-25, an oestrogen antagonist.
Acta endocrinologica.
1960 Aug; 34(?):531-5. doi:
10.1530/acta.0.xxxiv0531. [PMID: 14411475]
