FLUOROBENZENE (BioDeep_00001871831)

Main id: BioDeep_00000008573

 


代谢物信息卡片


FLUOROBENZENE

化学式: C6H5F (96.0375)
中文名称: 氟苯
谱图信息: 最多检出来源 Homo sapiens(blood) 65.38%

分子结构信息

SMILES: C1=CC=C(C=C1)F
InChI: InChI=1S/C6H5F/c7-6-4-2-1-3-5-6/h1-5H

描述信息

同义名列表

3 个代谢物同义名

FLUOROBENZENE; Fluorobenzene; Fluorobenzene



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AKR1B1, ALB, BTK, CA2, CAT, GSTM1, NOS3, PMP2, PSMA1, TYR
Peripheral membrane protein 2 BTK, CYP1B1
Endosome membrane 1 INSR
Endoplasmic reticulum membrane 1 CYP1B1
Nucleus 5 ALB, BTK, NOS3, PMP2, PSMA1
cytosol 9 AKR1B1, ALB, BTK, CA2, CAT, GSTM1, NOS3, PMP2, PSMA1
dendrite 2 HTR2A, HTR2C
centrosome 2 ALB, PSMA1
nucleoplasm 3 AKR1B1, NOS3, PSMA1
Cell membrane 6 BTK, CA2, HTR2A, HTR2C, INSR, OPRL1
Cell projection, axon 1 HTR2A
Multi-pass membrane protein 4 HTR2A, HTR2C, OPRL1, SLC45A2
Synapse 1 HTR2C
dendritic shaft 1 HTR2A
glutamatergic synapse 1 HTR2A
Golgi apparatus 3 ALB, ATRN, NOS3
Golgi membrane 1 NOS3
neuronal cell body 1 HTR2A
presynaptic membrane 1 HTR2A
Lysosome 2 INSR, TYR
Presynapse 1 HTR2A
plasma membrane 10 ATRN, BTK, CA2, HTR2A, HTR2C, INSR, ME2, ME3, NOS3, OPRL1
Membrane 6 CAT, CYP1B1, INSR, ME2, ME3, SLC45A2
axon 2 HTR2A, INSR
caveola 3 HTR2A, INSR, NOS3
extracellular exosome 8 AKR1B1, ALB, ATRN, CA2, CAT, INSR, PMP2, PSMA1
endoplasmic reticulum 1 ALB
extracellular space 3 AKR1B1, ALB, ATRN
perinuclear region of cytoplasm 3 BTK, NOS3, TYR
mitochondrion 5 AKR1B1, CAT, CYP1B1, ME2, ME3
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 4 CAT, CYP1B1, ME2, TYR
Microsome membrane 1 CYP1B1
Single-pass type I membrane protein 3 ATRN, INSR, TYR
Secreted 2 ALB, NPB
extracellular region 3 ALB, CAT, NPB
Single-pass membrane protein 2 ME2, ME3
neuronal cell body membrane 1 INSR
[Isoform 2]: Secreted 1 ATRN
Mitochondrion matrix 1 ME2
mitochondrial matrix 3 CAT, ME2, ME3
anchoring junction 1 ALB
external side of plasma membrane 1 INSR
cytoplasmic vesicle 3 BTK, HTR2A, OPRL1
Melanosome membrane 2 SLC45A2, TYR
Cytoplasm, P-body 1 NOS3
P-body 1 NOS3
apical part of cell 1 CA2
Golgi-associated vesicle 1 TYR
postsynaptic membrane 1 HTR2A
Membrane raft 1 BTK
focal adhesion 1 CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Late endosome 1 INSR
receptor complex 1 INSR
neuron projection 1 OPRL1
ciliary basal body 1 ALB
cytoskeleton 1 NOS3
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
[Isoform 3]: Secreted 1 ATRN
intercellular bridge 1 GSTM1
Membrane, caveola 1 HTR2A
cell body fiber 1 HTR2A
Cell projection, dendrite 1 HTR2A
Melanosome 1 TYR
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
myelin sheath 2 CA2, PMP2
ficolin-1-rich granule lumen 1 CAT
proteasome complex 1 PSMA1
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 ALB
platelet alpha granule lumen 1 ALB
endocytic vesicle membrane 1 NOS3
neurofilament 1 HTR2A
proteasome core complex 1 PSMA1
proteasome core complex, alpha-subunit complex 1 PSMA1
[Isoform 1]: Cell membrane 1 ATRN
dendrite membrane 1 INSR
catalase complex 1 CAT
insulin receptor complex 1 INSR
G protein-coupled serotonin receptor complex 2 HTR2A, HTR2C
ciliary transition fiber 1 ALB


文献列表

  • Jorge A Custodio-Mendoza, Ana Lopez Blanco, Ana M Ares-Fuentes, Antonia M Carro Díaz. Green infant formula analysis: Optimizing headspace solid-phase microextraction of carbonyl compounds associated with lipid peroxidation using GC-MS and pentafluorophenylhydrazine derivatization. Talanta. 2024 Jun; 273(?):125816. doi: 10.1016/j.talanta.2024.125816. [PMID: 38442561]
  • Sang-Hyeon Ju, Joung Youl Lim, Minchul Song, Ji Min Kim, Yea Eun Kang, Hyon-Seung Yi, Kyong Hye Joung, Ju Hee Lee, Hyun Jin Kim, Bon Jeong Ku. Distinct effects of rosuvastatin and rosuvastatin/ezetimibe on senescence markers of CD8+ T cells in patients with type 2 diabetes mellitus: a randomized controlled trial. Frontiers in endocrinology. 2024; 15(?):1336357. doi: 10.3389/fendo.2024.1336357. [PMID: 38586464]
  • Huaguang Zheng, Hongwei Li, Yilong Wang, Zhanquan Li, Bo Hu, Xiaogang Li, Lu Fu, Hongtao Hu, Zhiyu Nie, Bilian Zhao, Di Wei, Björn W Karlson, Michiel L Bots, XiangWen Meng, Yundai Chen, Yongjun Wang. Rosuvastatin Slows Progression of Carotid Intima-Media Thickness: The METEOR-China Randomized Controlled Study. Stroke. 2022 10; 53(10):3004-3013. doi: 10.1161/strokeaha.120.031877. [PMID: 36017704]
  • Wenjun Chen, Zourong Ruan, Jinliang Chen, Dandan Yang, Rong Shao, Honggang Lou, Bo Jiang. Population pharmacokinetics and enterohepatic recirculation of hyzetimibe and its main metabolite in Chinese healthy subjects. British journal of clinical pharmacology. 2022 07; 88(7):3153-3161. doi: 10.1111/bcp.15187. [PMID: 34931372]
  • Ana Vavlukis, Marija Vavlukis, Kristina Mladenovska, Aleksandar Dimovski, Natàlia Muñoz-García, Victoria de Santisteban Villaplana, Teresa Padro, Lina Badimon. Antioxidative Effects of Rosuvastatin in Low-to-Moderate Cardiovascular Risk Subjects. Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki). 2022 Apr; 43(1):65-75. doi: 10.2478/prilozi-2022-0007. [PMID: 35451294]
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  • Perrine Courlet, Monia Guidi, Susana Alves Saldanha, Felix Stader, Anna Traytel, Matthias Cavassini, Marcel Stoeckle, Thierry Buclin, Catia Marzolini, Laurent A Decosterd, Chantal Csajka. Pharmacokinetic/Pharmacodynamic Modelling to Describe the Cholesterol Lowering Effect of Rosuvastatin in People Living with HIV. Clinical pharmacokinetics. 2021 03; 60(3):379-390. doi: 10.1007/s40262-020-00946-3. [PMID: 33124006]
  • Margaret Mendi Njoroge, Ulrike Fillinger, Adam Saddler, Sarah Moore, Willem Takken, Joop J A van Loon, Alexandra Hiscox. Evaluating putative repellent 'push' and attractive 'pull' components for manipulating the odour orientation of host-seeking malaria vectors in the peri-domestic space. Parasites & vectors. 2021 Jan; 14(1):42. doi: 10.1186/s13071-020-04556-7. [PMID: 33430963]
  • Bin Gao, Lijuan Wang, Na Zhang, Miaomiao Han, Yubo Zhang, Huancai Liu, Dongli Sun, Yifei Liu. Screening Novel Drug Candidates for Kidney Renal Clear Cell Carcinoma Treatment: A Study on Differentially Expressed Genes through the Connectivity Map Database. Kidney & blood pressure research. 2021; 46(6):702-713. doi: 10.1159/000518437. [PMID: 34818247]
  • Stephen Turnock, David R Turton, Carlos Daniel Martins, Louis Chesler, Thomas C Wilson, Véronique Gouverneur, Graham Smith, Gabriela Kramer-Marek. 18F-meta-fluorobenzylguanidine (18F-mFBG) to monitor changes in norepinephrine transporter expression in response to therapeutic intervention in neuroblastoma models. Scientific reports. 2020 12; 10(1):20918. doi: 10.1038/s41598-020-77788-3. [PMID: 33262374]
  • Yilong Wang, Anxin Wang, Hongwei Li, Zhanquan Li, Bo Hu, Xiaogang Li, Huaguang Zheng, Lu Fu, Hongtao Hu, Zhiyu Nie, Yulin Qin, Bilian Zhao, Di Wei, Björn W Karlson, Michiel L Bots, Yundai Chen, Yongjun Wang. Measuring effects on intima-media thickness: an evaluation of rosuvastatin in Chinese subjects with subclinical atherosclerosis-design, rationale, and methodology of the METEOR-China study. Trials. 2020 Nov; 21(1):921. doi: 10.1186/s13063-020-04741-0. [PMID: 33176842]
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  • Perrine Courlet, Françoise Livio, Susana Alves Saldanha, Alexandra Scherrer, Manuel Battegay, Matthias Cavassini, Marcel Stoeckle, Laurent Arthur Decosterd, Catia Marzolini. Real-life management of drug-drug interactions between antiretrovirals and statins. The Journal of antimicrobial chemotherapy. 2020 07; 75(7):1972-1980. doi: 10.1093/jac/dkaa099. [PMID: 32240298]
  • Pallavi Bhargava, Jaroslav Janda, Rick G Schnellmann. Elucidation of cGMP-dependent induction of mitochondrial biogenesis through PKG and p38 MAPK in the kidney. American journal of physiology. Renal physiology. 2020 02; 318(2):F322-F328. doi: 10.1152/ajprenal.00533.2019. [PMID: 31841384]
  • Shinya Fujisawa, Yusuke Fukatsu, Yuya Sugimoto. [Atorvastatin-induced anemia accompanied by elevated serum LDH levels]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2020; 61(1):44-46. doi: 10.11406/rinketsu.61.44. [PMID: 32023602]
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  • Andrea M Santangelo, Steve J Sawiak, Tim Fryer, Young Hong, Yoshiro Shiba, Hannah F Clarke, Patrick J Riss, Valentina Ferrari, Roger Tait, John Suckling, Franklin I Aigbirhio, Angela C Roberts. Insula serotonin 2A receptor binding and gene expression contribute to serotonin transporter polymorphism anxious phenotype in primates. Proceedings of the National Academy of Sciences of the United States of America. 2019 07; 116(29):14761-14768. doi: 10.1073/pnas.1902087116. [PMID: 31266890]
  • Jun Abe, Yoshitaka Tomigahara, Hirokazu Tarui, Hirohisa Nagahori, Motohiro Kurosawa, Kenji Sugimoto, Naohiko Isobe. Metabolism of metofluthrin in rats: II. Excretion, distribution and amount of metabolites. Xenobiotica; the fate of foreign compounds in biological systems. 2018 Nov; 48(11):1113-1127. doi: 10.1080/00498254.2017.1397813. [PMID: 29157071]
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  • Liang-Chih Liu, Yao-Chung Wu, Sheng-Chu Kuo, Chi-Tang Ho, Tzong-DER Way, Shou-Tung Chen. 2-Phenylnaphthyridin-4-one Derivative LYF-11 Inhibits Interleukin-6-mediated Epithelial-to-Mesenchymal Transition via the Inhibition of JAK2/STAT3 Signaling Pathway in MCF-7 Cells. Anticancer research. 2018 05; 38(5):2849-2859. doi: 10.21873/anticanres.12530. [PMID: 29715108]
  • Xue-Qing Chen, Theresa Ziemba, Christine Huang, Ming Chang, Carrie Xu, Jennifer X Qiao, Tammy C Wang, Heather J Finlay, Mark E Salvati, Leonard P Adam, Olafur Gudmundsson, Michael J Hageman. Oral Delivery of Highly Lipophilic, Poorly Water-Soluble Drugs: Self-Emulsifying Drug Delivery Systems to Improve Oral Absorption and Enable High-Dose Toxicology Studies of a Cholesteryl Ester Transfer Protein Inhibitor in Preclinical Species. Journal of pharmaceutical sciences. 2018 05; 107(5):1352-1360. doi: 10.1016/j.xphs.2018.01.003. [PMID: 29317226]
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  • Chayanon Ngambenjawong, Heather H Gustafson, Meilyn Sylvestre, Suzie H Pun. A Facile Cyclization Method Improves Peptide Serum Stability and Confers Intrinsic Fluorescence. Chembiochem : a European journal of chemical biology. 2017 12; 18(24):2395-2398. doi: 10.1002/cbic.201700446. [PMID: 29044914]
  • Xiaoguang Sunny Li, Shu Li, Gottfried Kellermann. A simple dilute and shoot approach incorporated with pentafluorophenyl (PFP) column based LC-MS/MS assay for the simultaneous determination of trimethylamine N-oxide and trimethylamine in spot urine samples with high throughput. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Nov; 1067(?):61-70. doi: 10.1016/j.jchromb.2017.09.049. [PMID: 29017075]
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  • Dimitrios Tsikas. GC-ECNICI-MS/MS of eicosanoids as pentafluorobenzyl-trimethylsilyl (TMS) derivatives: Evidence of CAD-induced intramolecular TMS ether-to-ester rearrangement using carboxy-18O-labelled eicosanoids and possible implications in quantitative analysis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Mar; 1047(?):185-196. doi: 10.1016/j.jchromb.2016.06.018. [PMID: 27352806]
  • Dimitrios Tsikas, Arslan Arinc Kayacelebi, Erik Hanff, Anja Mitschke, Bibiana Beckmann, Hanns-Christian Tillmann, Frank-Mathias Gutzki, Meike Müller, Corrado Bernasconi. GC-MS and GC-MS/MS measurement of ibuprofen in 10-μL aliquots of human plasma and mice serum using [α-methylo-2H3]ibuprofen after ethyl acetate extraction and pentafluorobenzyl bromide derivatization: Discovery of a collision energy-dependent H/D isotope effect and pharmacokinetic application to inhaled ibuprofen-arginine in mice. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Feb; 1043(?):158-166. doi: 10.1016/j.jchromb.2016.06.014. [PMID: 27343144]
  • Erik Hanff, Michele F Eisenga, Bibiana Beckmann, Stephan J L Bakker, Dimitrios Tsikas. Simultaneous pentafluorobenzyl derivatization and GC-ECNICI-MS measurement of nitrite and malondialdehyde in human urine: Close positive correlation between these disparate oxidative stress biomarkers. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Feb; 1043(?):167-175. doi: 10.1016/j.jchromb.2016.07.027. [PMID: 27461359]
  • Dimitrios Tsikas. Pentafluorobenzyl bromide-A versatile derivatization agent in chromatography and mass spectrometry: I. Analysis of inorganic anions and organophosphates. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Feb; 1043(?):187-201. doi: 10.1016/j.jchromb.2016.08.015. [PMID: 27561968]
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  • Dimitrios Tsikas, Sabine Rothmann, Jessica Y Schneider, Maria-Theresia Suchy, Arne Trettin, Darko Modun, Nadine Stuke, Norbert Maassen, Jürgen C Frölich. Development, validation and biomedical applications of stable-isotope dilution GC-MS and GC-MS/MS techniques for circulating malondialdehyde (MDA) after pentafluorobenzyl bromide derivatization: MDA as a biomarker of oxidative stress and its relation to 15(S)-8-iso-prostaglandin F2α and nitric oxide (NO). Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2016 Apr; 1019(?):95-111. doi: 10.1016/j.jchromb.2015.10.009. [PMID: 26522895]
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