butadiene (BioDeep_00001871693)

Main id: BioDeep_00000011191

 


代谢物信息卡片


polybutadiene diacrylate

化学式: C4H6 (54.046947599999996)
中文名称: 聚丁二烯, 丁二烯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=CC=C
InChI: InChI=1S/C4H6/c1-3-4-2/h3-4H,1-2H2

描述信息

D009676 - Noxae > D002273 - Carcinogens
D009676 - Noxae > D009153 - Mutagens

同义名列表

4 个代谢物同义名

polybutadiene diacrylate; buta-1,3-diene; 1,3-BUTADIENE; butadiene



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Boonwiset Seaho, Chatkamon Lekwongphaiboon, Wichayasith Inthakusol, Saisuree Prateeptongkum, Wacharee Harnying, Albrecht Berkessel, Nongnaphat Duangdee. NMR-based stability evaluation of (E)-1-(3',4'-dimethoxyphenyl)butadiene (DMPBD) from Zingiber cassumunar Roxb. rhizome. Phytochemical analysis : PCA. 2024 Apr; 35(3):579-585. doi: 10.1002/pca.3314. [PMID: 38130156]
  • Jiameng Huang, Lin Zhu, Xiaomin Lu, Feng Cui, Jianfei Wang, Cheng Zhou. A simplified synthetic rhizosphere bacterial community steers plant oxylipin pathways for preventing foliar phytopathogens. Plant physiology and biochemistry : PPB. 2023 Aug; 202(?):107941. doi: 10.1016/j.plaphy.2023.107941. [PMID: 37549573]
  • Vahid Ahmadi-Moshiran, Ali Asghar Sajedian, Ahmad Soltanzadeh, Fatemeh Seifi, Rozhin Koobasi, Neda Nikbakht, Mohsen Sadeghi-Yarandi. Carcinogenic and health risk assessment of respiratory exposure to acrylonitrile, 1,3-butadiene and styrene in the petrochemical industry using the US Environmental Protection Agency method. International journal of occupational safety and ergonomics : JOSE. 2022 Dec; 28(4):i-ix. doi: 10.1080/10803548.2022.2059171. [PMID: 35363589]
  • Luke Erber, Samantha Goodman, Fred A Wright, Weihsueh A Chiu, Natalia Y Tretyakova, Ivan Rusyn. Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following Inhalation Exposure to 1,3-Butadiene. Chemical research in toxicology. 2021 11; 34(11):2375-2383. doi: 10.1021/acs.chemrestox.1c00291. [PMID: 34726909]
  • Mary Nellis, Caitlin O Caperton, Ken Liu, ViLinh Tran, Young-Mi Go, Lance M Hallberg, Bill T Ameredes, Dean P Jones, Gunnar Boysen. Lung metabolome of 1,3-butadiene exposed Collaborative Cross mice reflects metabolic phenotype of human lung cancer. Toxicology. 2021 11; 463(?):152987. doi: 10.1016/j.tox.2021.152987. [PMID: 34648870]
  • Nalini Sathiakumar, Bolanle Bolaji, Ilene Brill, Ligong Chen, Meghan Tipre, Mark Leader, Tarun Arora, Elizabeth Delzell. 1,3-Butadiene, styrene and selected outcomes among synthetic rubber polymer workers: Updated exposure-response analyses. Chemico-biological interactions. 2021 Sep; 347(?):109600. doi: 10.1016/j.cbi.2021.109600. [PMID: 34324853]
  • Alma Nieto, Luyu Zhang, Deepak Bhandari, Wanzhe Zhu, Benjamin C Blount, Víctor R De Jesús. Exposure to 1,3-Butadiene in the U.S. Population: National Health and Nutrition Examination Survey 2011-2016. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2021 Jun; 26(4):371-383. doi: 10.1080/1354750x.2021.1904000. [PMID: 33729088]
  • Caitlin C Jokipii Krueger, S Lani Park, Guru Madugundu, Yesha Patel, Loic Le Marchand, Daniel O Stram, Natalia Tretyakova. Ethnic differences in excretion of butadiene-DNA adducts by current smokers. Carcinogenesis. 2021 05; 42(5):694-704. doi: 10.1093/carcin/bgab020. [PMID: 33693566]
  • Ming-Huei Cheng, Chun-Hui Chiu, Chi-Tsung Chen, Hsu-Huan Chou, Li-Heng Pao, Gwo-Hwa Wan. Sources and components of volatile organic compounds in breast surgery operating rooms. Ecotoxicology and environmental safety. 2021 Feb; 209(?):111855. doi: 10.1016/j.ecoenv.2020.111855. [PMID: 33385676]
  • Juan C Stockert. Lipid Peroxidation Assay Using BODIPY-Phenylbutadiene Probes: A Methodological Overview. Methods in molecular biology (Clifton, N.J.). 2021; 2202(?):199-214. doi: 10.1007/978-1-0716-0896-8_16. [PMID: 32857357]
  • Mohsen Sadeghi-Yarandi, Ali Karimi, Vahid Ahmadi, Ali Asghar Sajedian, Ahmad Soltanzadeh, Farideh Golbabaei. Cancer and non-cancer health risk assessment of occupational exposure to 1,3-butadiene in a petrochemical plant in Iran. Toxicology and industrial health. 2020 Dec; 36(12):960-970. doi: 10.1177/0748233720962238. [PMID: 33108261]
  • Heike Sigloch, Frank S Bierkandt, Ajay V Singh, Ashish K Gadicherla, Peter Laux, Andreas Luch. 3D Printing - Evaluating Particle Emissions of a 3D Printing Pen. Journal of visualized experiments : JoVE. 2020 10; ?(164):. doi: 10.3791/61829. [PMID: 33104072]
  • Chien-Yu Lin, Hui-Ling Lee, Wei-Ting Jung, Fung-Chang Sung, Ta-Chen Su. The association between urinary levels of 1,3-butadiene metabolites, cardiovascular risk factors, microparticles, and oxidative stress products in adolescents and young adults. Journal of hazardous materials. 2020 09; 396(?):122745. doi: 10.1016/j.jhazmat.2020.122745. [PMID: 32361133]
  • Caitlin C Jokipii Krueger, Guru Madugundu, Amanda Degner, Yesha Patel, Daniel O Stram, Timothy R Church, Natalia Tretyakova. Urinary N7-(1-hydroxy-3-buten-2-yl) guanine adducts in humans: temporal stability and association with smoking. Mutagenesis. 2020 02; 35(1):19-26. doi: 10.1093/mutage/gez030. [PMID: 31702786]
  • Haiyan Cheng, Wen Jin, Xinhua Huang, Xiao Liu, Feng Wang, Xiaoyu Guo, Yiping Wu, Ye Ying, Ying Wen, Haifeng Yang. A flexible carbon nanotube-modified poly(styrene-butadiene)-based dopamine sensor. Nanotechnology. 2020 Jan; 31(1):015505. doi: 10.1088/1361-6528/ab4373. [PMID: 31509820]
  • Wen-Jing Wu, Wei-Feng Tang, Ming-Hui Xiang, Jianshe Yan, Xiumei Cao, Chang-Hui Zhou, Yan Chang, Jing Xi, Yi-Yi Cao, Yang Luan, Xin-Yu Zhang. Isotope dilution LC/ESI--MS-MS quantitation of urinary 1,4-bis(N-acetyl-S-cysteinyl)-2-butanone in mice and rats as the biomarker of 1-chloro-2-hydroxy-3-butene, an in vitro metabolite of 1,3-butadiene. Chemico-biological interactions. 2019 Sep; 311(?):108760. doi: 10.1016/j.cbi.2019.108760. [PMID: 31348916]
  • Lauren Lewis, Barbara Borowa-Mazgaj, Aline de Conti, Grace A Chappell, Yu-Syuan Luo, Wanda Bodnar, Kranti Konganti, Fred A Wright, David W Threadgill, Weihsueh A Chiu, Igor P Pogribny, Ivan Rusyn. Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse. Chemical research in toxicology. 2019 05; 32(5):887-898. doi: 10.1021/acs.chemrestox.9b00035. [PMID: 30990016]
  • Charles Pudrith, William N Dudley. Sensorineural hearing loss and volatile organic compound metabolites in urine. American journal of otolaryngology. 2019 May; 40(3):409-412. doi: 10.1016/j.amjoto.2019.03.001. [PMID: 30871731]
  • Lauren Lewis, Grace A Chappell, Tetyana Kobets, Bridget E O'Brian, Dewakar Sangaraju, Oksana Kosyk, Wanda Bodnar, Natalia Y Tretyakova, Igor P Pogribny, Ivan Rusyn. Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues. Archives of toxicology. 2019 03; 93(3):791-800. doi: 10.1007/s00204-018-2374-x. [PMID: 30552462]
  • Jennifer W Israel, Grace A Chappell, Jeremy M Simon, Sebastian Pott, Alexias Safi, Lauren Lewis, Paul Cotney, Hala S Boulos, Wanda Bodnar, Jason D Lieb, Gregory E Crawford, Terrence S Furey, Ivan Rusyn. Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription. Mammalian genome : official journal of the International Mammalian Genome Society. 2018 02; 29(1-2):153-167. doi: 10.1007/s00335-018-9739-6. [PMID: 29429127]
  • Emily J Boldry, Yesha M Patel, Srikanth Kotapati, Amanda Esades, Sungshim L Park, Maarit Tiirikainen, Daniel O Stram, Loïc Le Marchand, Natalia Tretyakova. Genetic Determinants of 1,3-Butadiene Metabolism and Detoxification in Three Populations of Smokers with Different Risks of Lung Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2017 07; 26(7):1034-1042. doi: 10.1158/1055-9965.epi-16-0838. [PMID: 28292921]
  • N Karami, A Karimi, A Aliahmadi, F Mirzajan, H Rezadoost, A Ghassempour, F Fallah. Identification of bacteria using volatile organic compounds. Cellular and molecular biology (Noisy-le-Grand, France). 2017 Feb; 63(2):112-121. doi: 10.14715/cmb/2017.63.2.18. [PMID: 28364792]
  • Dewakar Sangaraju, Emily J Boldry, Yesha M Patel, Vernon Walker, Irina Stepanov, Daniel Stram, Dorothy Hatsukami, Natalia Tretyakova. Isotope Dilution nanoLC/ESI+-HRMS3 Quantitation of Urinary N7-(1-Hydroxy-3-buten-2-yl) Guanine Adducts in Humans and Their Use as Biomarkers of Exposure to 1,3-Butadiene. Chemical research in toxicology. 2017 02; 30(2):678-688. doi: 10.1021/acs.chemrestox.6b00407. [PMID: 27997139]
  • Ormrat Kampeerawipakorn, Panida Navasumrit, Daam Settachan, Jeerawan Promvijit, Potchanee Hunsonti, Varabhorn Parnlob, Netnapa Nakngam, Suppachai Choonvisase, Passaornrawan Chotikapukana, Samroeng Chanchaeamsai, Mathuros Ruchirawat. Health risk evaluation in a population exposed to chemical releases from a petrochemical complex in Thailand. Environmental research. 2017 Jan; 152(?):207-213. doi: 10.1016/j.envres.2016.10.004. [PMID: 27792945]
  • Claudia Bolognesi, Micheline Kirsch-Volders. The ex vivo L-CBMN assay detects significant human exposure to butadiene. Mutation research. Reviews in mutation research. 2016 Oct; 770(Pt A):73-83. doi: 10.1016/j.mrrev.2016.04.001. [PMID: 27894692]
  • Nalini Sathiakumar, Ilene Brill, Mark Leader, Elizabeth Delzell. 1,3-Butadiene, styrene and lymphohematopoietic cancer among male synthetic rubber industry workers--Preliminary exposure-response analyses. Chemico-biological interactions. 2015 Nov; 241(?):40-9. doi: 10.1016/j.cbi.2015.09.003. [PMID: 26343807]
  • Srikanth Kotapati, Amanda Esades, Brock Matter, Chap Le, Natalia Tretyakova. High throughput HPLC-ESI(-)-MS/MS methodology for mercapturic acid metabolites of 1,3-butadiene: Biomarkers of exposure and bioactivation. Chemico-biological interactions. 2015 Nov; 241(?):23-31. doi: 10.1016/j.cbi.2015.02.009. [PMID: 25727266]
  • Xiaotao Zhang, Hongwei Hou, Huan Chen, Yong Liu, An Wang, Qingyuan Hu. A column-switching LC-MS/MS method for simultaneous quantification of biomarkers for 1,3-butadiene exposure and oxidative damage in human urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Oct; 1002(?):123-9. doi: 10.1016/j.jchromb.2015.08.012. [PMID: 26319305]
  • Jerry Campbell, Cynthia Van Landingham, Susan Crowell, Robinan Gentry, Debra Kaden, Stacy Fiebelkorn, Anne Loccisano, Harvey Clewell. A preliminary regional PBPK model of lung metabolism for improving species dependent descriptions of 1,3-butadiene and its metabolites. Chemico-biological interactions. 2015 Aug; 238(?):102-10. doi: 10.1016/j.cbi.2015.05.025. [PMID: 26079054]
  • Menglong Xiang, Lei Sun, Xiaomei Dong, Huan Yang, Wen-bin Liu, Niya Zhou, Xue Han, Ziyuan Zhou, Zhihong Cui, Jing-yi Liu, Jia Cao, Lin Ao. Association between Genetic Polymorphisms of DNA Repair Genes and Chromosomal Damage for 1,3-Butadiene-Exposed Workers in a Matched Study in China. BioMed research international. 2015; 2015(?):234675. doi: 10.1155/2015/234675. [PMID: 26339595]
  • Grace Chappell, Tetyana Kobets, Bridget O'Brien, Natalia Tretyakova, Dewakar Sangaraju, Oksana Kosyk, Kenneth G Sexton, Wanda Bodnar, Igor P Pogribny, Ivan Rusyn. Epigenetic events determine tissue-specific toxicity of inhalational exposure to the genotoxic chemical 1,3-butadiene in male C57BL/6J mice. Toxicological sciences : an official journal of the Society of Toxicology. 2014 Dec; 142(2):375-84. doi: 10.1093/toxsci/kfu191. [PMID: 25237060]
  • Sungshim Lani Park, Srikanth Kotapati, Lynne R Wilkens, Maarit Tiirikainen, Sharon E Murphy, Natalia Tretyakova, Loïc Le Marchand. 1,3-Butadiene exposure and metabolism among Japanese American, Native Hawaiian, and White smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2014 Nov; 23(11):2240-9. doi: 10.1158/1055-9965.epi-14-0492. [PMID: 25368399]
  • Mariella Carrieri, Giovanni B Bartolucci, Enrico Paci, Paolo Sacco, Daniela Pigini, Laura Zaratin, Danilo Cottica, Maria L Scapellato, Giovanna Tranfo. Validation of a radial diffusive sampler for measuring occupational exposure to 1,3-butadiene. Journal of chromatography. A. 2014 Aug; 1353(?):114-20. doi: 10.1016/j.chroma.2014.02.018. [PMID: 24602307]
  • Srikanth Kotapati, Dewakar Sangaraju, Amanda Esades, Lance Hallberg, Vernon E Walker, James A Swenberg, Natalia Y Tretyakova. Bis-butanediol-mercapturic acid (bis-BDMA) as a urinary biomarker of metabolic activation of butadiene to its ultimate carcinogenic species. Carcinogenesis. 2014 Jun; 35(6):1371-8. doi: 10.1093/carcin/bgu047. [PMID: 24531806]
  • Raffaela Fuccelli, Maria Vittoria Sepporta, Patrizia Rosignoli, Guido Morozzi, Maurizio Servili, Roberto Fabiani. Preventive activity of olive oil phenolic compounds on alkene epoxides induced oxidative DNA damage on human peripheral blood mononuclear cells. Nutrition and cancer. 2014; 66(8):1322-30. doi: 10.1080/01635581.2014.956251. [PMID: 25299479]
  • K Udeni Alwis, Benjamin C Blount, April S Britt, Dhrusti Patel, David L Ashley. Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI/MSMS). Analytica chimica acta. 2012 Oct; 750(?):152-60. doi: 10.1016/j.aca.2012.04.009. [PMID: 23062436]
  • Xue-mei Cheng, Yan-ni Jiao, Jin-dong Chen, Bao-de Shan, Zhao-lin Xia. [Study on urine biomarkers in 1,3-butadiene exposed workers]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. 2012 Sep; 30(9):661-6. doi: NULL. [PMID: 23257089]
  • Roberto Fabiani, Patrizia Rosignoli, Angelo De Bartolomeo, Raffaela Fuccelli, Guido Morozzi. Genotoxicity of alkene epoxides in human peripheral blood mononuclear cells and HL60 leukaemia cells evaluated with the comet assay. Mutation research. 2012 Aug; 747(1):1-6. doi: 10.1016/j.mrgentox.2012.01.004. [PMID: 22285587]
  • Katharina Sterz, Gerhard Scherer, Jan Krumsiek, Fabian J Theis, Josef Ecker. Identification and quantification of 1-hydroxybutene-2-yl mercapturic acid in human urine by UPLC- HILIC-MS/MS as a novel biomarker for 1,3-butadiene exposure. Chemical research in toxicology. 2012 Aug; 25(8):1565-7. doi: 10.1021/tx3002862. [PMID: 22817647]
  • Beatrice Vitali, Maurice Ndagijimana, Simone Maccaferri, Elena Biagi, Maria Elisabetta Guerzoni, Patrizia Brigidi. An in vitro evaluation of the effect of probiotics and prebiotics on the metabolic profile of human microbiota. Anaerobe. 2012 Aug; 18(4):386-91. doi: 10.1016/j.anaerobe.2012.04.014. [PMID: 22579985]
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