DESMOPRESSIN (BioDeep_00001871408)
代谢物信息卡片
(Deamino-Cys1,D-Arg8)-Vasopressin acetate salt
化学式: C46H64N14O12S2 (1068.4269344)
中文名称: [去氨基-Cys1, D-Arg8]-加压素 乙酸盐 水合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(N(C1)C(=O)C2CSSCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N
InChI: InChI=1S/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29+,30+,31+,32+,33+,34+/m1/s1
描述信息
H - Systemic hormonal preparations, excl. sex hormones and insulins > H01 - Pituitary and hypothalamic hormones and analogues > H01B - Posterior pituitary lobe hormones > H01BA - Vasopressin and analogues
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C80212 - Antidiuretic Hormone Analogue
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents > D014667 - Vasopressins
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics
D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents
D045283 - Natriuretic Agents > D050034 - Antidiuretic Agents
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:4450
- PubChem: 5311065
- DrugBank: DB00035
- ChEMBL: CHEMBL1429
- MeSH: Deamino Arginine Vasopressin
- CAS: 16679-58-6
- CAS: 113-81-5
- KEGG: C06944
- PubChem: 9159
- KNApSAcK: 4450
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- G Marroncini, C Anceschi, L Naldi, B Fibbi, M Brogi, L Lanzilao, A Fanelli, M Maggi, A Peri. Hyponatremia-related liver steatofibrosis and impaired spermatogenesis: evidence from a mouse model of the syndrome of inappropriate antidiuresis.
Journal of endocrinological investigation.
2022 Nov; ?(?):. doi:
10.1007/s40618-022-01962-9. [PMID: 36436190] - Johannes Kalbhenn, Hannah Glonnegger, Martin Büchsel, Hans-Joachim Priebe, Barbara Zieger. Acquired von Willebrand Syndrome and Desmopressin Resistance During Venovenous Extracorporeal Membrane Oxygenation in Patients With COVID-19: A Prospective Observational Study.
Critical care medicine.
2022 08; 50(8):1246-1255. doi:
10.1097/ccm.0000000000005467. [PMID: 35234414] - Michelle Gunther, Corey J Witenko, Morgan Prust, David Salerno, Karen Berger. The Safety and Efficacy of Desmopressin in Patients With Intracranial Hemorrhage and a History of Alcohol Use.
Journal of intensive care medicine.
2022 Jun; 37(6):825-832. doi:
10.1177/08850666211031494. [PMID: 34286612] - Helbert Rondon-Berrios, Richard H Sterns. Hypertonic Saline for Hyponatremia: Meeting Goals and Avoiding Harm.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2022 06; 79(6):890-896. doi:
10.1053/j.ajkd.2021.07.020. [PMID: 34508830] - Ali Yavari, Zahra Sharifan, Bagher Larijani, Ali Mosadegh Khah. Central diabetes insipidus secondary to COVID-19 infection: a case report.
BMC endocrine disorders.
2022 May; 22(1):134. doi:
10.1186/s12902-022-01048-w. [PMID: 35590312] - Ye-Ji Kim, Jei Ha Lee, Seung-Hyun Jung, Ki Hyun Kim, Chang-Hoon Choi, Seonmi Jo, Dong Ho Woo. An Octopus-Derived Peptide with Antidiuretic Activity in Rats.
Marine drugs.
2022 May; 20(5):. doi:
10.3390/md20050328. [PMID: 35621979] - Reema Habiby, Daniel G Bichet, Marie-Francoise Arthus, Dervia Connaughton, Shirlee Shril, Shrikant Mane, Amar J Majmundar, Friedhelm Hildebrandt, Gary L Robertson. A Novel Form of Familial Vasopressin Deficient Diabetes Insipidus Transmitted in an X-linked Recessive Manner.
The Journal of clinical endocrinology and metabolism.
2022 05; 107(6):e2513-e2522. doi:
10.1210/clinem/dgac076. [PMID: 35137152] - Qihua Wang, Rami Alshayyah, Bo Yang. The efficacy and safety of desmopressin acetate applied for nocturia in benign prostatic hyperplasia patients: A systematic review and meta-analysis.
Lower urinary tract symptoms.
2022 May; 14(3):155-162. doi:
10.1111/luts.12423. [PMID: 35034423] - Mladena Glavaš, Agata Gitlin-Domagalska, Dawid Dębowski, Natalia Ptaszyńska, Anna Łęgowska, Krzysztof Rolka. Vasopressin and Its Analogues: From Natural Hormones to Multitasking Peptides.
International journal of molecular sciences.
2022 Mar; 23(6):. doi:
10.3390/ijms23063068. [PMID: 35328489] - Jessica M Heijdra, Wala Al Arashi, Nico C B de Jager, Michael E Cloesmeijer, Laura H Bukkems, Christian M Zwaan, Frank W G Leebeek, Ron A A Mathôt, Marjon H Cnossen. Is pharmacokinetic-guided dosing of desmopressin and von Willebrand factor-containing concentrates in individuals with von Willebrand disease or low von Willebrand factor reliable and feasible? A protocol for a multicentre, non-randomised, open label cohort trial, the OPTI-CLOT: to WiN study.
BMJ open.
2022 Feb; 12(2):e049493. doi:
10.1136/bmjopen-2021-049493. [PMID: 35168962] - Neeti Agrawal, Avivar Awasthi, Partha Pratim Chakraborty, Animesh Maiti. Desmopressin treatment in dipsogenic form of primary polydipsia: keep serum osmolality marginally below thirst threshold for symptomatic relief.
BMJ case reports.
2022 Feb; 15(2):. doi:
10.1136/bcr-2021-247488. [PMID: 35110290] - Guy Decaux. Low Creatininuria due to Hyponatremia Is Reversible in Many Patients.
Nephron.
2022; 146(1):40-44. doi:
10.1159/000519049. [PMID: 34583361] - R A Misgar, A Rasool, A I Wani, M I Bashir. Central diabetes insipidus (Infundibuloneuro hypophysitis): A late complication of COVID-19 infection.
Journal of endocrinological investigation.
2021 Dec; 44(12):2855-2856. doi:
10.1007/s40618-021-01627-z. [PMID: 34215999] - Athaya Febriantyo Purnomo, Besut Daryanto, Pradana Nurhadi. Monosymptomatic Nocturnal Enuresis Treatment Using Alarm-Therapy and Desmopressin: A Meta-analysis Approach.
Medical archives (Sarajevo, Bosnia and Herzegovina).
2021 Dec; 75(6):431-435. doi:
10.5455/medarh.2021.75.431-435. [PMID: 35169370] - Claudia G Vasquez, Vipul T Vachharajani, Carlos Garzon-Coral, Alexander R Dunn. Physical basis for the determination of lumen shape in a simple epithelium.
Nature communications.
2021 09; 12(1):5608. doi:
10.1038/s41467-021-25050-3. [PMID: 34556639] - Michael J R Desborough, Samya Obaji, Gillian C Lowe, Carolyn Doree, Will Thomas. Management of surgery, menorrhagia and child-birth for patients with unclassified bleeding disorders: a systematic review of cohort studies.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
2021 Sep; 32(6):366-372. doi:
10.1097/mbc.0000000000001045. [PMID: 33973892] - Pamela Galati, Todd Archer, Robyn Jolly, Alyssa Sullivant, Robert Wills, Patty Lathan. Effects of desmopressin acetate administration in healthy dogs receiving prednisolone.
Journal of veterinary internal medicine.
2021 Sep; 35(5):2271-2276. doi:
10.1111/jvim.16250. [PMID: 34448503] - Ali Gözüküçük, Mehmet Kılıç, Basri Çakıroğlu. Desmopressin versus desmopressin + oxybutynin in the treatment of children with nocturnal enuresis.
Journal of pediatric urology.
2021 08; 17(4):451.e1-451.e6. doi:
10.1016/j.jpurol.2021.04.001. [PMID: 33931318] - Naruhiro Jingushi, Seiichiro Tsuzuki, Kenichiro Fujii, Norimichi Uenishi, Mitsunaga Iwata, Teruhiko Terasawa. Association of intranasal desmopressin therapy with overcorrection of severe hyponatremia: A retrospective, propensity score-based, single-center cohort study.
Journal of critical care.
2021 08; 64(?):53-61. doi:
10.1016/j.jcrc.2021.03.010. [PMID: 33794467] - Sonja Izquierdo Riis Meyer, Cecilie Siggaard Jørgensen, Konstantinos Kamperis, René Frydensberg Andersen, Malthe Jessen Pedersen, Mia Faerch, Søren Rittig. Efficacy and safety of multimodal treatment in nocturnal enuresis - A retrospective cohort study.
Journal of pediatric urology.
2021 08; 17(4):447.e1-447.e7. doi:
10.1016/j.jpurol.2021.03.005. [PMID: 33820712] - S Abdovic, M Cuk, I Hizar, M Milosevic, A Jerkovic, M Saraga. Pretreatment morning urine osmolality and oral desmopressin lyophilisate treatment outcome in patients with primary monosymptomatic enuresis.
International urology and nephrology.
2021 Aug; 53(8):1529-1534. doi:
10.1007/s11255-021-02843-5. [PMID: 33774753] - Natasha Alford, Hashim Hashim. Desmopressin acetate the first sublingual tablet to treat nocturia due to nocturnal polyuria.
Expert review of clinical pharmacology.
2021 Aug; 14(8):939-954. doi:
10.1080/17512433.2021.1931122. [PMID: 33993824] - Jingtao Qiao, Jiaqi Li, Weiwei Zhang, Chun Wang, Jianwei Li, Shu Jiang, Huiwen Tan, Yaxi Chen, Hui Liu, Bowen Cai, Yerong Yu. The usefulness of the combined high-dose dexamethasone suppression test and desmopressin stimulation test in establishing the source of ACTH secretion in ACTH-dependent Cushing's syndrome.
Endocrine journal.
2021 Jul; 68(7):839-848. doi:
10.1507/endocrj.ej20-0837. [PMID: 33790062] - Azuma Nanamatsu, Takayasu Mori, Fumiaki Ando, Taisuke Furusho, Shintaro Mandai, Koichiro Susa, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. Vasopressin Induces Urinary Uromodulin Secretion By Activating PKA (Protein Kinase A).
Hypertension (Dallas, Tex. : 1979).
2021 06; 77(6):1953-1963. doi:
10.1161/hypertensionaha.121.17127. [PMID: 33896194] - Lena K Tran, Kaylee K Marino, Jeremy R DeGrado, Paul M Szumita, Kevin M Dube. Evaluation of Desmopressin in Critically Ill Patients with Hyponatremia Requiring 3\% Hypertonic Saline.
The American journal of the medical sciences.
2021 06; 361(6):711-717. doi:
10.1016/j.amjms.2021.03.012. [PMID: 33812910] - Lien Dossche, Robin Michelet, Pauline De Bruyne, Charlotte Van Herzeele, Elke Gasthuys, Søren Rittig, An Vermeulen, Johan Vande Walle. Desmopressin oral lyophilisate in young children: new insights in pharmacokinetics and pharmacodynamics.
Archives of disease in childhood.
2021 06; 106(6):597-602. doi:
10.1136/archdischild-2019-318225. [PMID: 32737054] - Cédric Mahiat, Antoine Capes, Thierry Duprez, Nicolas Whenham, Lionel Duck, Laura Labriola. Central diabetes insipidus induced by temozolomide: A report of two cases.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2021 Jun; 27(4):1040-1045. doi:
10.1177/1078155220961551. [PMID: 32990192] - Hyongmin Oh, Hyeon Cheun, Yoon Jung Kim, Hyun-Kyu Yoon, Ho Kang, Hyung-Chul Lee, Hee-Pyoung Park, Jung Hee Kim, Yong Hwy Kim. Cephalocaudal tumor diameter is a predictor of diabetes insipidus after endoscopic transsphenoidal surgery for non-functioning pituitary adenoma.
Pituitary.
2021 Jun; 24(3):303-311. doi:
10.1007/s11102-020-01108-1. [PMID: 33191457] - Lama Al-Qusairi, P Richard Grimm, Ava M Zapf, Paul A Welling. Rapid development of vasopressin resistance in dietary K+ deficiency.
American journal of physiology. Renal physiology.
2021 05; 320(5):F748-F760. doi:
10.1152/ajprenal.00655.2020. [PMID: 33749322] - Hideki Oe, Hatsumi Yoshiki, Xinmin Zha, Hisato Kobayashi, Yoshitaka Aoki, Hideaki Ito, Osamu Yokoyama. Urinary reabsorption in the rat kidney by anticholinergics.
Scientific reports.
2021 04; 11(1):9191. doi:
10.1038/s41598-021-88738-y. [PMID: 33911165] - Shuzo Kaneko, Joichi Usui, Kunio Kawanishi, Ryota Ishii, Kazuhiro Takahashi, Hiroaki Suzuki, Chie Saito, Tatsuya Oda, Michio Nagata, Kunihiro Yamagata. Unusual ischemic kidney injury presenting as slowly declining graft function and successful use of oral desmopressin in a kidney transplant recipient with subclinical central diabetes insipidus.
Clinical nephrology.
2021 Apr; 95(4):208-214. doi:
10.5414/cn110295. [PMID: 33560220] - Cynthia C Lim, Hui Zhuan Tan, Chieh Suai Tan, Helen Healy, Jason Choo, Pedro Henrique Franca Gois. Desmopressin acetate to prevent bleeding in percutaneous kidney biopsy: a systematic review.
Internal medicine journal.
2021 Apr; 51(4):571-579. doi:
10.1111/imj.14774. [PMID: 32040251] - Cecilie S Jørgensen, Henriette T Horsdal, Veera M Rajagopal, Jakob Grove, Thomas D Als, Konstantinos Kamperis, Mette Nyegaard, G Bragi Walters, Viðar Örn Eðvarðsson, Hreinn Stefánsson, Merete Nordentoft, David Michael Hougaard, Thomas Werge, Ole Mors, Preben Bo Mortensen, Esben Agerbo, Søren Rittig, Kári Stefánsson, Anders D Børglum, Ditte Demontis, Jane H Christensen. Identification of genetic loci associated with nocturnal enuresis: a genome-wide association study.
The Lancet. Child & adolescent health.
2021 03; 5(3):201-209. doi:
10.1016/s2352-4642(20)30350-3. [PMID: 33453761] - Adrien Flahault, Pierre-Emmanuel Girault-Sotias, Mathilde Keck, Rodrigo Alvear-Perez, Nadia De Mota, Lucie Estéoulle, Sridévi M Ramanoudjame, Xavier Iturrioz, Dominique Bonnet, Catherine Llorens-Cortes. A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia.
Nature communications.
2021 01; 12(1):305. doi:
10.1038/s41467-020-20560-y. [PMID: 33436646] - Keiichiro Hayashi, Kohzo Fuji, Madoka Omizu, Aya Hiramatsu, Shintaro Koizumi, Eiji Matsubara, Katsuyuki Saito, Motoki Yamagishi, Haruaki Sasaki, Takashi Fukagai, Kimiyasu Ishikawa, Yoshio Ogawa. [INITIAL TREATMENT OF NOCTURIA CAUSED BY NOCTURNAL POLYURIA WITH LOW-DOSE DESMOPRESSIN].
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology.
2021; 112(1):18-24. doi:
10.5980/jpnjurol.112.18. [PMID: 35046231] - Konstantinos Kamperis. Nocturnal enuresis in children: The role of arginine-vasopressin.
Handbook of clinical neurology.
2021; 181(?):289-297. doi:
10.1016/b978-0-12-820683-6.00021-x. [PMID: 34238464] - Faith Kim, Helen M Towers. Management of transient central diabetes insipidus with intravenous desmopressin in a premature infant with gastroschisis and septo-optic dysplasia: A case report.
Journal of neonatal-perinatal medicine.
2021; 14(2):293-297. doi:
10.3233/npm-200465. [PMID: 32804104] - Melanie Lohrberg, Anne Winkler, Jonas Franz, Franziska van der Meer, Torben Ruhwedel, Nikoloz Sirmpilatze, Rakshit Dadarwal, Ronja Handwerker, Daniel Esser, Kerstin Wiegand, Christian Hagel, Andreas Gocht, Fatima Barbara König, Susann Boretius, Wiebke Möbius, Christine Stadelmann, Alonso Barrantes-Freer. Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination.
Acta neuropathologica communications.
2020 12; 8(1):224. doi:
10.1186/s40478-020-01105-2. [PMID: 33357244] - Nico C B de Jager, Jessica M Heijdra, Marcel Pistorius, Marieke J H A Kruip, Frank W G Leebeek, Marjon H Cnossen, Ron A A Mathôt. A Novel Quantitative Method for Analyzing Desmopressin in Human Plasma Using Liquid Chromatography-Tandem Mass Spectrometry.
Therapeutic drug monitoring.
2020 12; 42(6):880-885. doi:
10.1097/ftd.0000000000000791. [PMID: 32694360] - Björn Peters, Salmir Nasic, Gert Jensen, Bernd Stegmayr. Renal transplant biopsy complications: assessment of risk factors and potential of desmopressin to decrease risk of hemorrhage.
Acta radiologica (Stockholm, Sweden : 1987).
2020 Dec; 61(12):1717-1723. doi:
10.1177/0284185120910590. [PMID: 32212828] - Kara Suvada, Laura Plantinga, Camille P Vaughan, Alayne D Markland, Anna Mirk, Kathryn L Burgio, Susanne M Erni, Mohammed K Ali, Ike Okosun, Henry Young, Patricia S Goode, Theodore M Johnson. Comorbidities, Age, and Polypharmacy Limit the Use by US Older Adults with Nocturia of the Only FDA-approved Drugs for the Symptom.
Clinical therapeutics.
2020 12; 42(12):e259-e274. doi:
10.1016/j.clinthera.2020.11.003. [PMID: 33257091] - Krister Bamberg, Lena William-Olsson, Ulrika Johansson, Anders Arner, Judith Hartleib-Geschwindner, Johan Sällström. Electrolyte handling in the isolated perfused rat kidney: demonstration of vasopressin V2-receptor-dependent calcium reabsorption.
Upsala journal of medical sciences.
2020 Nov; 125(4):274-280. doi:
10.1080/03009734.2020.1804496. [PMID: 32812807] - Amir Gal-Oz, Amitay Papushado, Ilya Kirgner, Shmuel Meirsdorf, Doron Schwartz, Idit Francesca Schwartz, Asia Zubkov, Ayelet Grupper. Thromboelastography versus bleeding time for risk of bleeding post native kidney biopsy.
Renal failure.
2020 Nov; 42(1):10-18. doi:
10.1080/0886022x.2019.1700805. [PMID: 31842662] - Abrar Hussain, R John Baier, Ayman Abou Mehrem, Hanifi Soylu, Debbie Fraser, Yasser Elsayed. Central Diabetes Insipidus in a Preterm Neonate Unresponsive to Intranasal Desmopressin.
Neonatal network : NN.
2020 Nov; 39(6):339-346. doi:
10.1891/0730-0832/11-t-679. [PMID: 33318230] - Beniamino Palmieri, Tommaso Iannitti, Julio Cesar Morales-Medina, Maria Vadalà. Monocentric single-arm study of desmopressin acetate efficacy on nocturnal polyuria in the elderly.
International journal of clinical practice.
2020 Nov; 74(11):e13612. doi:
10.1111/ijcp.13612. [PMID: 32668490] - Lei-Yi Yang, Sang Lin, Qi-Bing Xie, Geng Yin. Central diabetes insipidus unveiled by glucocorticoid therapy in a patient with an empty sella: A case report and literature review.
Medicine.
2020 Oct; 99(43):e22939. doi:
10.1097/md.0000000000022939. [PMID: 33120853] - Soledad Iseas, Enrique L Roca, Juan M O'Connor, Martin Eleta, Analia Sanchez-Luceros, Daniela Di Leo, Marcelo Tinelli, Maria L Fara, Eduardo Spitzer, Ignacio A Demarco, Giselle V Ripoll, Marina Pifano, Juan Garona, Daniel F Alonso. Administration of the vasopressin analog desmopressin for the management of bleeding in rectal cancer patients: results of a phase I/II trial.
Investigational new drugs.
2020 10; 38(5):1580-1587. doi:
10.1007/s10637-020-00914-5. [PMID: 32166534] - Sebastian Schwab, Simon Lissmann, Niklas Schäfer, Alexander Isaak, Dietrich Klingmüller, Ulrike Attenberger, Anna M Eis-Hübinger, Jörg Hofmann, Christian P Strassburg, Philipp Lutz. When polyuria does not stop: a case report on an unusual complication of hantavirus infection.
BMC infectious diseases.
2020 Sep; 20(1):713. doi:
10.1186/s12879-020-05429-1. [PMID: 32993515] - Hanyu Lou, Yimin Shen, Yi Xu, Wei Zhang, Yuezhong Ren. Nephrogenic diabetes insipidus induced by ureter obstruction due to benign prostatic hyperplasia: A case report.
Medicine.
2020 Sep; 99(37):e22082. doi:
10.1097/md.0000000000022082. [PMID: 32925747] - Craig D Seaman, Margaret V Ragni. The Effect of Age on von Willebrand Factor and Bleeding Symptoms in von Willebrand Disease.
Thrombosis and haemostasis.
2020 Aug; 120(8):1159-1165. doi:
10.1055/s-0040-1713636. [PMID: 32629500] - Elke Gasthuys, Lien Dossche, Robin Michelet, Jens Peter Nørgaard, Mathias Devreese, Siska Croubels, An Vermeulen, Jan Van Bocxlaer, Johan Vande Walle. Pediatric Pharmacology of Desmopressin in Children with Enuresis: A Comprehensive Review.
Paediatric drugs.
2020 Aug; 22(4):369-383. doi:
10.1007/s40272-020-00401-7. [PMID: 32507959] - Nidhi Dwivedi, Shixin Tao, Abeda Jamadar, Sonali Sinha, Christianna Howard, Darren P Wallace, Timothy A Fields, Andrew Leask, James P Calvet, Reena Rao. Epithelial Vasopressin Type-2 Receptors Regulate Myofibroblasts by a YAP-CCN2-Dependent Mechanism in Polycystic Kidney Disease.
Journal of the American Society of Nephrology : JASN.
2020 08; 31(8):1697-1710. doi:
10.1681/asn.2020020190. [PMID: 32554753] - Kazumasa Torimoto, Makito Miyake, Yasushi Nakai, Katsuya Aoki, Nobumichi Tanaka, Kiyohide Fujimoto. Rationale, design, and methods of electroencephalography-based investigation of the effects of oral desmopressin on improving slow-wave sleep time in nocturnal polyuria patients (the DISTINCT study): protocol for a single-arm, open-label, single-assignment trial.
BMC urology.
2020 Jul; 20(1):96. doi:
10.1186/s12894-020-00668-5. [PMID: 32652972] - Katarina D Kovacevic, Nina Buchtele, Christian Schoergenhofer, Ulla Derhaschnig, Georg Gelbenegger, Christine Brostjan, Shuhao Zhu, James C Gilbert, Bernd Jilma. The aptamer BT200 effectively inhibits von Willebrand factor (VWF) dependent platelet function after stimulated VWF release by desmopressin or endotoxin.
Scientific reports.
2020 07; 10(1):11180. doi:
10.1038/s41598-020-68125-9. [PMID: 32636459] - Björn Peters. Response to Letter to the Editor 'Hyponatremia may be an under-recognised complication after desmopressin to reduce uremic bleeding in kidney biopsy'.
Nephrology (Carlton, Vic.).
2020 07; 25(7):584. doi:
10.1111/nep.13694. [PMID: 31950552] - Nina Buchtele, Katarina D Kovacevic, Christine Brostjan, Michael Schwameis, Hubert Hayden, Ulla Derhaschnig, Christa Firbas, Bernd Jilma, Christian Schoergenhofer. Differential Osteoprotegerin Kinetics after Stimulation with Desmopressin and Lipopolysaccharides In Vivo.
Thrombosis and haemostasis.
2020 Jul; 120(7):1108-1115. doi:
10.1055/s-0040-1712448. [PMID: 32483770] - Mirjam Christ-Crain, Ewout J Hoorn, Mark Sherlock, Chris J Thompson, John A H Wass. ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of diabetes insipidus and hyponatraemia.
European journal of endocrinology.
2020 Jul; 183(1):G9-G15. doi:
10.1530/eje-20-0338. [PMID: 32380474] - Mohamed Elshafei, Mohammed I Danjuma, Rania El Tahir. Therapeutic challenges in the management of osmotic demyelination syndrome: A case report of a favorable outcome from a tertiary center.
Medicine.
2020 Jun; 99(24):e20283. doi:
10.1097/md.0000000000020283. [PMID: 32541452] - Elisabet Lundmark, Tryggve Neve Us. The prognostic value of voiding chart data in therapy-resistant enuresis.
Journal of pediatric urology.
2020 06; 16(3):353.e1-353.e6. doi:
10.1016/j.jpurol.2020.02.020. [PMID: 32423706] - Shohei Akagawa, Shoji Tsuji, Yuko Akagawa, Sohsaku Yamanouchi, Takahisa Kimata, Kazunari Kaneko. Desmopressin response in nocturnal enuresis showing concentrated urine.
Pediatrics international : official journal of the Japan Pediatric Society.
2020 Jun; 62(6):701-704. doi:
10.1111/ped.14201. [PMID: 32065484] - Li-Chun Wang, Ying-Fang Hu, Lei Chen, Rui Xing, Xin-Feng Lin, Qiu-Ye Kou. Desmopressin acetate decreases blood loss in patients with massive hemorrhage undergoing gastrointestinal surgery.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology.
2020 06; 31(6):474-481. doi:
10.5152/tjg.2020.19021. [PMID: 32721919] - Shi Chen, Kang Chen, Shirui Wang, Huijuan Zhu, Lin Lu, Xiaobo Zhang, Anli Tong, Hui Pan, Renzhi Wang, Zhaolin Lu. The Optimal Cut-off of BIPSS in Differential Diagnosis of ACTH-dependent Cushing's Syndrome: Is Stimulation Necessary?.
The Journal of clinical endocrinology and metabolism.
2020 04; 105(4):. doi:
10.1210/clinem/dgz194. [PMID: 31758170] - Germán Pérez Suárez, Alma Serrano, María Victoria Magallanes, Pedro Arango Sancho, María Isabel Luis Yanes, Víctor M García Nieto. Longitudinal study of kidney water management in patients diagnosed with idiopathic hypercalciuria in childhood.
Nefrologia.
2020 Mar; 40(2):190-196. doi:
10.1016/j.nefro.2019.07.003. [PMID: 31806292] - Inge Durie, Gaby van Galen. Long-term hormone replacement treatment in a horse with central diabetes insipidus.
Journal of veterinary internal medicine.
2020 Mar; 34(2):1013-1017. doi:
10.1111/jvim.15697. [PMID: 31960998] - Quan Yao Ho, Cynthia C Lim, Sobhana Thangaraju, Benson Siow, Yok Mooi Chin, Ying Hao, Puay Hoon Lee, Marjorie Foo, Chieh Suai Tan, Terence Kee. Bleeding Complications and Adverse Events After Desmopressin Acetate for Percutaneous Renal Transplant Biopsy.
Annals of the Academy of Medicine, Singapore.
2020 Feb; 49(2):52-64. doi:
10.47102/annals-acadmedsg.2019164. [PMID: 32246706] - Luca Bordoni, Eugenio Gutiérrez Jiménez, Søren Nielsen, Leif Østergaard, Sebastian Frische. A new experimental mouse model of water intoxication with sustained increased intracranial pressure and mild hyponatremia without side effects of antidiuretics.
Experimental animals.
2020 Jan; 69(1):92-103. doi:
10.1538/expanim.19-0040. [PMID: 31534063] - Simona Raso, Catherine Lambert, Ana Boban, Mariasanta Napolitano, Sergio Siragusa, Cedric Hermans. Can we compare haemophilia carriers with clotting factor deficiency to male patients with mild haemophilia?.
Haemophilia : the official journal of the World Federation of Hemophilia.
2020 Jan; 26(1):117-121. doi:
10.1111/hae.13891. [PMID: 31815335] - Hortensia De la Corte-Rodriguez, E Carlos Rodriguez-Merchan, M Teresa Alvarez-Roman, Monica Martin-Salces, Victor Jimenez-Yuste. 'Do not Do' Recommendations in Hemophilia.
Cardiovascular & hematological disorders drug targets.
2020; 20(3):168-174. doi:
10.2174/1871529x20666200305111323. [PMID: 32133968] - Robin Michelet, Lien Dossche, Charlotte Van Herzeele, Pauline De Bruyne, Elke Gasthuys, Jan Van Bocxlaer, Johan Vande Walle, An Vermeulen. An Integrated Paediatric Population PK/PD Analysis of dDAVP: How do PK Differences Translate to Clinical Outcomes?.
Clinical pharmacokinetics.
2020 01; 59(1):81-96. doi:
10.1007/s40262-019-00798-6. [PMID: 31347012] - Shoji Tsuji, Tadashi Yamaguchi, Yuko Akagawa, Shohei Akagawa, Jiro Kino, Sohsaku Yamanouchi, Takahisa Kimata, Kazunari Kaneko. High daily salt intake had a negative impact on how well nocturnal enuresis treatment worked on children aged 7-10 years.
Acta paediatrica (Oslo, Norway : 1992).
2020 01; 109(1):193-197. doi:
10.1111/apa.14922. [PMID: 31254367] - Laura Droctové, Manon Lancien, Vu Long Tran, Michaël Susset, Benoit Jego, Frederic Theodoro, Pascal Kessler, Gilles Mourier, Philippe Robin, Sékou Siramakan Diarra, Stefano Palea, Adrien Flahault, Amélia Chorfa, Maithé Corbani, Catherine Llorens-Cortes, Bernard Mouillac, Christiane Mendre, Alain Pruvost, Denis Servent, Charles Truillet, Nicolas Gilles. A snake toxin as a theranostic agent for the type 2 vasopressin receptor.
Theranostics.
2020; 10(25):11580-11594. doi:
10.7150/thno.47485. [PMID: 33052234] - Osamu Yamaguchi, Kristian V Juul, Ali Falahati, Toru Yoshimura, Futoshi Imura, Mikiya Kitamura. Efficacy and safety of 25 and 50 μg desmopressin orally disintegrating tablets in Japanese patients with nocturia due to nocturnal polyuria: Results from two phase 3 studies of a multicenter randomized double-blind placebo-controlled parallel-group development program.
Lower urinary tract symptoms.
2020 Jan; 12(1):8-19. doi:
10.1111/luts.12276. [PMID: 31397969] - Annarita Di Mise, Maria Venneri, Marianna Ranieri, Mariangela Centrone, Lorenzo Pellegrini, Grazia Tamma, Giovanna Valenti. Lixivaptan, a New Generation Diuretic, Counteracts Vasopressin-Induced Aquaporin-2 Trafficking and Function in Renal Collecting Duct Cells.
International journal of molecular sciences.
2019 Dec; 21(1):. doi:
10.3390/ijms21010183. [PMID: 31888044] - Weibin Zhou, Jia Rao, Chengjiang Li. Isolated Langerhans cell histiocytosis in the hypothalamic-pituitary region: a case report.
BMC endocrine disorders.
2019 Dec; 19(1):143. doi:
10.1186/s12902-019-0474-0. [PMID: 31856773] - Pier Mannuccio Mannucci. New therapies for von Willebrand disease.
Hematology. American Society of Hematology. Education Program.
2019 12; 2019(1):590-595. doi:
10.1182/hematology.2019000368. [PMID: 31808884] - Susan Oliver, Thiru Vanniasinkam, Soma Mohammed, Ronny Vong, Emmanuel J Favaloro. Semi-automated von Willebrand factor multimer assay for von Willebrand disease: Further validation, benefits and limitations.
International journal of laboratory hematology.
2019 Dec; 41(6):762-771. doi:
10.1111/ijlh.13107. [PMID: 31508897] - Elizabeth A Feldman, Gregory Meola, Stephanie Zyck, Christopher D Miller, Satish Krishnamurthy, Gregory M Cwikla, William Darko, Shane Jennings, Ross Sullivan, Robert Seabury. Retrospective Assessment of Desmopressin Effectiveness and Safety in Patients With Antiplatelet-Associated Intracranial Hemorrhage.
Critical care medicine.
2019 12; 47(12):1759-1765. doi:
10.1097/ccm.0000000000004021. [PMID: 31567345] - Ambarish Athavale, Hemant Kulkarni, Cagil D Arslan, Peter Hart. Desmopressin and bleeding risk after percutaneous kidney biopsy.
BMC nephrology.
2019 11; 20(1):413. doi:
10.1186/s12882-019-1595-4. [PMID: 31730448] - Xiang Cai, Yiyang Tian, Ming Nie, Kunjie Wang. Efficacy and safety of desmopressin in women with nocturia: a systematic review and meta-analysis of randomized controlled trials.
International urology and nephrology.
2019 Nov; 51(11):1913-1923. doi:
10.1007/s11255-019-02242-x. [PMID: 31352583] - Yosuke Morizawa, Katsuya Aoki, Yusuke Iemura, Shunta Hori, Daisuke Gotoh, Shinji Fukui, Yasushi Nakai, Makito Miyake, Kazumasa Torimoto, Nobumichi Tanaka, Kiyohide Fujimoto. Urinary nerve growth factor can predict therapeutic efficacy in children with monosymptomatic nocturnal enuresis.
Neurourology and urodynamics.
2019 11; 38(8):2311-2317. doi:
10.1002/nau.24142. [PMID: 31432572] - S Passanisi, G D'Angelo, L Marseglia, C De Cola, R Granese, G Conti, P Betta, M C Cutrupi, C Fede, R Chimenz, C Salpietro, E Gitto. Renal anomalies in newborns with vacterel association: case series and literature review.
Journal of biological regulators and homeostatic agents.
2019 Sep; 33(5 Suppl. 1):53-58. Special Issue: Focus on Pediatric Nephrology. doi:
NULL. [PMID: 31630714] - Luciano D Mendoza, Kelly A Hyndman. The contribution of collecting duct NOS1 to the concentrating mechanisms in male and female mice.
American journal of physiology. Renal physiology.
2019 09; 317(3):F547-F559. doi:
10.1152/ajprenal.00180.2019. [PMID: 31241990] - Yu Gu, Xuefeng Sun, Min Peng, Ting Zhang, Juhong Shi, Jiangfeng Mao. Pituitary involvement in patients with granulomatosis with polyangiitis: case series and literature review.
Rheumatology international.
2019 Aug; 39(8):1467-1476. doi:
10.1007/s00296-019-04338-0. [PMID: 31203400] - Cynthia C Lim, Huijun Huang, Yok M Chin, Wei L Teng, Keng T Woo. Kidney biopsy in the elderly: Safety and strategies to prevent uremic bleeding.
Nephrology (Carlton, Vic.).
2019 08; 24(8):876. doi:
10.1111/nep.13528. [PMID: 31050083] - Gianni Biancofiore, Annabel Blasi, Marieke T De Boer, Massimo Franchini, Matthias Hartmann, Ton Lisman, Giancarlo M Liumbruno, Robert J Porte, Fuat Saner, Marco Senzolo, Maureen J Werner. Perioperative hemostatic management in the cirrhotic patient: a position paper on behalf of the Liver Intensive Care Group of Europe (LICAGE).
Minerva anestesiologica.
2019 Jul; 85(7):782-798. doi:
10.23736/s0375-9393.19.13468-2. [PMID: 30945514] - Yanli Ma, Ying Shen. Letter about: nocturnal enuresis in children between laser acupuncture and medical treatment-a comparative study.
Lasers in medical science.
2019 07; 34(5):1049-1050. doi:
10.1007/s10103-018-2660-0. [PMID: 30298301] - Yalda Ravanshad, Anoush Azarfar, Mohammad Esmaeeli, Zahra Mostafavian, Elham Zahabi, Sahar Ravanshad. Effect of Low Dose Imipramine in Patients with Nocturnal Enuresis, A Randomized Clinical Trial.
Iranian journal of kidney diseases.
2019 07; 13(4):257-261. doi:
. [PMID: 31422392] - Cynthia C Lim, Mayank Chawla, Benson Siow, Jason C J Choo, Puay Hoon Lee, Marjorie Foo, Chieh Suai Tan. Hyponatremia may be an under-recognized complication after desmopressin to reduce uremic bleeding in kidney biopsy.
Nephrology (Carlton, Vic.).
2019 Jun; 24(6):674. doi:
10.1111/nep.13398. [PMID: 31006950] - Cynthia C Lim, Benson Siow, Jason C J Choo, Mayank Chawla, Yok Mooi Chin, Terence Kee, Puay Hoon Lee, Marjorie Foo, Chieh Suai Tan. Desmopressin for the prevention of bleeding in percutaneous kidney biopsy: efficacy and hyponatremia.
International urology and nephrology.
2019 Jun; 51(6):995-1004. doi:
10.1007/s11255-019-02155-9. [PMID: 31028561] - Davide Viggiano, Natale G De Santo, Nagoth Joseph Amruthraj, Giovanna Capolongo, Giovambattista Capasso, Pietro Anastasio. Renal response to an oral protein load in patients with central diabetes insipidus before and after treatment with vasopressin.
Journal of nephrology.
2019 Jun; 32(3):411-415. doi:
10.1007/s40620-018-00575-x. [PMID: 30778919] - Kazimierz Wiśniewski, Steve Qi, John Kraus, Brian Ly, Karthik Srinivasan, Hiroe Tariga, Glenn Croston, Erin La, Halina Wiśniewska, Carlos Ortiz, Régent Laporte, Pierre J-M Rivière, Gebhard Neyer, Diane M Hargrove, Claudio D Schteingart. Discovery of Potent, Selective, and Short-Acting Peptidic V2 Receptor Agonists.
Journal of medicinal chemistry.
2019 05; 62(10):4991-5005. doi:
10.1021/acs.jmedchem.9b00132. [PMID: 31022340] - W Weinrebe, S Käbe-Frisch, I Füsgen, M Karaman, E Johannsdottir, S Rupp. Do independent geriatric outpatients with nocturnal polyuria profit from desmopressin?.
Zeitschrift fur Gerontologie und Geriatrie.
2019 May; 52(3):272-278. doi:
10.1007/s00391-018-1379-7. [PMID: 29541862] - P Kozler, D Marešová, J Pokorný. Loss of body weight is accompanying cellular brain edema induced by water intoxication in the rat.
Physiological research.
2019 04; 68(2):321-324. doi:
10.33549/physiolres.934077. [PMID: 30628836] - Karl-Erik Andersson, James Longstreth, Benjamin M Brucker, Lysanne Campeau, Linda Cheng, Leo Francis, Seymour Fein. Pharmacokinetic and Pharmacodynamic Properties of a Micro-Dose Nasal Spray Formulation of Desmopressin (AV002) in Healthy Water-Loaded Subjects.
Pharmaceutical research.
2019 Apr; 36(6):92. doi:
10.1007/s11095-019-2628-1. [PMID: 31037429] - Lisette M Schütte, Marjon H Cnossen, Reinier M van Hest, Mariette H E Driessens, Karin Fijnvandraat, Suzanne Polinder, Erik A M Beckers, Michiel Coppens, Jeroen Eikenboom, Britta A P Laros-van Gorkom, Karina Meijer, Laurens Nieuwenhuizen, Evelien P Mauser-Bunschoten, Frank W G Leebeek, Ron A A Mathôt, Marieke J H A Kruip. Desmopressin treatment combined with clotting factor VIII concentrates in patients with non-severe haemophilia A: protocol for a multicentre single-armed trial, the DAVID study.
BMJ open.
2019 04; 9(4):e022719. doi:
10.1136/bmjopen-2018-022719. [PMID: 31015264] - M J Hou, Z Q Yu, Z N Ma, W Zhang, X Bai, L J Cao, J Su, P P Sha, Z Y Wang, C G Ruan. [Clinical observation of desmopressin in the treatment of 15 patients with DDAVP].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi.
2019 Apr; 40(4):312-316. doi:
10.3760/cma.j.issn.0253-2727.2019.04.009. [PMID: 31104443] - P Marzuillo, R Marotta, S Guarino, M C Fedele, F Palladino, D Capalbo, N Della Vecchia, E Miraglia Del Giudice, C Polito, A La Manna. 'Frequently recurring' nocturnal polyuria is predictive of response to desmopressin in monosymptomatic nocturnal enuresis in childhood.
Journal of pediatric urology.
2019 Apr; 15(2):166.e1-166.e7. doi:
10.1016/j.jpurol.2018.11.004. [PMID: 30528650] - Y Ma, Y Shen, X Liu. Constipation in nocturnal enuresis may interfere desmopressin management success.
Journal of pediatric urology.
2019 Apr; 15(2):177.e1-177.e6. doi:
10.1016/j.jpurol.2018.11.019. [PMID: 30594475] - Ayako Ito, Aya Nozaki, Ichiro Horie, Takao Ando, Atsushi Kawakami. Relation between change in treatment for central diabetes insipidus and body weight loss.
Minerva endocrinologica.
2019 Mar; 44(1):85-90. doi:
10.23736/s0391-1977.18.02718-9. [PMID: 29424204]