o-phospho-l-tyrosine (BioDeep_00001868577)

Main id: BioDeep_00000003169

 


代谢物信息卡片


o-phospho-l-tyrosine

化学式: C9H12NO6P (261.0402)
中文名称: O-磷酸基-L-酪氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1CC(C(=O)O)N)OP(=O)(O)O
InChI: InChI=1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/t8-/m0/s1

描述信息

同义名列表

2 个代谢物同义名

o-phospho-l-tyrosine; Phosphotyrosine



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 AKT1, GRB2, JAK2, MARK2, PIK3C3, PIK3R1, PLEK, PRKX, PTPN11, PTPN6, PTS, SYK, TNK1
Peripheral membrane protein 2 JAK2, TNK1
Endosome membrane 1 INSR
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 8 AKT1, GRB2, JAK2, PIK3R1, PRKX, PTPN11, PTPN6, SYK
autophagosome 1 PIK3C3
cytosol 12 AKT1, GRB2, JAK2, LCK, PIK3C3, PIK3R1, PLEK, PRKCQ, PTPN11, PTPN6, PTS, SYK
dendrite 1 MARK2
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
nucleoplasm 7 AKT1, GRB2, JAK2, MARK2, PRKX, PTPN11, PTPN6
Cell membrane 6 AKT1, INSR, ITGAM, LCK, PTPRC, SYK
Lipid-anchor 1 LCK
Cytoplasmic side 1 LCK
lamellipodium 1 AKT1
ruffle membrane 1 PLEK
Synapse 1 PTPRC
cell cortex 2 AKT1, GRB2
cell surface 2 ITGAM, PTPRC
glutamatergic synapse 3 AKT1, JAK2, PIK3C3
Golgi apparatus 1 GRB2
Golgi membrane 1 INS
postsynapse 2 AKT1, JAK2
Cytoplasm, cytosol 2 LCK, SYK
Lysosome 1 INSR
endosome 2 GRB2, PIK3C3
plasma membrane 14 AKT1, GRB2, INSR, ITGAM, JAK2, LCK, MARK2, PIK3R1, PLEK, PRKCQ, PTPN6, PTPRC, SYK, TNK1
Membrane 11 AKT1, INSR, ITGAM, JAK2, MARK2, PIK3C3, PIK3R1, PLEK, PTPN6, PTPRC, TNK1
axon 1 INSR
caveola 2 INSR, JAK2
extracellular exosome 6 GRB2, INSR, ITGAM, LCK, PTPN6, PTPRC
extracellular space 3 IGF1, INS, ITGAM
perinuclear region of cytoplasm 1 PIK3R1
mitochondrion 3 MARK2, PTPN11, PTS
protein-containing complex 4 AKT1, PTPN11, PTPN6, SYK
Single-pass type I membrane protein 3 INSR, ITGAM, PTPRC
Secreted 2 IGF1, INS
extracellular region 4 IGF1, INS, PLEK, PTPN6
cytoplasmic side of plasma membrane 2 JAK2, PTPRC
neuronal cell body membrane 1 INSR
centriolar satellite 1 PRKCQ
external side of plasma membrane 3 INSR, ITGAM, PTPRC
microtubule cytoskeleton 1 AKT1
nucleolus 2 GRB2, PTPN6
midbody 1 PIK3C3
cell-cell junction 4 AKT1, GRB2, PIK3R1, PTPN6
vesicle 1 AKT1
Membrane raft 4 ITGAM, JAK2, LCK, PTPRC
focal adhesion 2 JAK2, PTPRC
spindle 1 AKT1
GABA-ergic synapse 1 PIK3C3
cis-Golgi network 1 PIK3R1
perinuclear endoplasmic reticulum membrane 1 PIK3R1
Peroxisome 1 PIK3C3
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
lateral plasma membrane 1 MARK2
axoneme 1 PIK3C3
Late endosome 2 INSR, PIK3C3
receptor complex 1 INSR
ciliary basal body 1 AKT1
phagocytic vesicle membrane 1 PIK3C3
cytoskeleton 1 JAK2
COP9 signalosome 1 GRB2
actin filament 1 MARK2
Endomembrane system 1 JAK2
endosome lumen 2 INS, JAK2
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
Cell projection, dendrite 1 MARK2
specific granule membrane 1 ITGAM
tertiary granule membrane 1 ITGAM
euchromatin 1 JAK2
exocytic vesicle 1 IGF1
plasma membrane raft 1 ITGAM
secretory granule lumen 1 INS
secretory granule membrane 1 PTPRC
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
platelet alpha granule lumen 1 IGF1
phosphatidylinositol 3-kinase complex 1 PIK3R1
phosphatidylinositol 3-kinase complex, class IA 1 PIK3R1
specific granule lumen 1 PTPN6
tertiary granule lumen 1 PTPN6
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 2 LCK, PRKCQ
presynaptic endosome 1 PIK3C3
aggresome 1 PRKCQ
vesicle membrane 1 GRB2
extrinsic component of cytoplasmic side of plasma membrane 1 JAK2
dendrite membrane 1 INSR
early phagosome 1 SYK
pericentriolar material 1 LCK
extrinsic component of plasma membrane 1 JAK2
granulocyte macrophage colony-stimulating factor receptor complex 1 JAK2
interleukin-12 receptor complex 1 JAK2
interleukin-23 receptor complex 1 JAK2
integrin complex 1 ITGAM
membrane microdomain 1 PTPRC
postsynaptic endosome 1 PIK3C3
bleb 1 PTPRC
T cell receptor complex 1 SYK
alpha-beta T cell receptor complex 1 PTPN6
Autolysosome 1 PIK3C3
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
integrin alphaM-beta2 complex 1 ITGAM
insulin receptor complex 1 INSR
B cell receptor complex 1 SYK
Grb2-EGFR complex 1 GRB2
microtubule bundle 1 MARK2


文献列表

  • Wonhwa Cho, Kyli Berkley, Ashutosh Sharma. Lipid Binding of SH2 Domains. Methods in molecular biology (Clifton, N.J.). 2023; 2705(?):239-253. doi: 10.1007/978-1-0716-3393-9_13. [PMID: 37668978]
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  • S R Tie, D J McCarthy, T S Kendrick, A Louw, C Le, J Satiaputra, N Kucera, M Phillips, E Ingley. Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway. Oncogene. 2016 Apr; 35(16):2098-111. doi: 10.1038/onc.2015.272. [PMID: 26212012]
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