Testosterone Enanthate (BioDeep_00001867888)
Main id: BioDeep_00000001998
代谢物信息卡片
化学式: C26H40O3 (400.2977)
中文名称: 庚酸睾酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCC(=O)OC1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
InChI: InChI=1S/C26H40O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h17,20-23H,4-16H2,1-3H3/t20-,21-,22-,23-,25-,26-/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D000728 - Androgens
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
同义名列表
2 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:9464
- KEGG: C08157
- KEGGdrug: D00958
- PubChem: 9416
- DrugBank: DB13944
- ChEMBL: CHEMBL1200335
- CAS: 315-37-7
- MetaboLights: MTBLC9464
- PubChem: 10357
- LipidMAPS: LMST02020075
- 3DMET: B02148
- NIKKAJI: J5.664B
- RefMet: Testosterone enanthate
- KNApSAcK: 9464
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Abdulmohsin J Alamoudi, Sami A Alessi, Waleed Y Rizg, Abdulmajeed M Jali, Awaji Y Safhi, Fahad Y Sabei, Sameer Alshehri, Khaled M Hosny, Ashraf B Abdel-Naim. Cordycepin Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats via Modulation of AMPK and AKT Activation.
Pharmaceutics.
2022 Aug; 14(8):. doi:
10.3390/pharmaceutics14081652
. [PMID: 36015278] - Edward J Choi, Perry Xu, Farouk M El-Khatib, Parviz K Kavoussi, Faysal A Yafi. Post-market safety and efficacy profile of subcutaneous testosterone enanthate-autoinjector: a cohort analysis.
International journal of impotence research.
2022 Aug; 34(5):467-470. doi:
10.1038/s41443-021-00435-6
. [PMID: 34007063] - Samira Shirooie, Ehsan Khaledi, Ahmad Reza Dehpour, Tayebeh Noori, Mozafar Khazaei, Faezeh Sadeghi, Eduardo Sobarzo-Sánchez. The effect of dapsone in testosterone enanthate-induced polycystic ovary syndrome in rat.
The Journal of steroid biochemistry and molecular biology.
2021 11; 214(?):105977. doi:
10.1016/j.jsbmb.2021.105977
. [PMID: 34428594] - Grace Huang, Karol Pencina, Zhuoying Li, Caroline M Apovian, Thomas G Travison, Thomas W Storer, Thiago Gagliano-Jucá, Shehzad Basaria, Shalender Bhasin. Effect of Protein Intake on Visceral Abdominal Fat and Metabolic Biomarkers in Older Men With Functional Limitations: Results From a Randomized Clinical Trial.
The journals of gerontology. Series A, Biological sciences and medical sciences.
2021 05; 76(6):1084-1089. doi:
10.1093/gerona/glab007
. [PMID: 33417663] - Jovana Joksimovic Jovic, Jasmina Sretenovic, Nikola Jovic, Jovan Rudic, Vladimir Zivkovic, Ivan Srejovic, Katarina Mihajlovic, Nevena Draginic, Marijana Andjic, Milica Milinkovic, Zoran Milosavljevic, Vladimir Jakovljevic. Cardiovascular Properties of the Androgen-Induced PCOS Model in Rats: The Role of Oxidative Stress.
Oxidative medicine and cellular longevity.
2021; 2021(?):8862878. doi:
10.1155/2021/8862878
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Nov; 131(?):110759. doi:
10.1016/j.biopha.2020.110759
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Biology of sex differences.
2020 08; 11(1):48. doi:
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Andrologia.
2020 Apr; 52(3):e13516. doi:
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The aging male : the official journal of the International Society for the Study of the Aging Male.
2020 Mar; 23(1):23-28. doi:
10.1080/13685538.2018.1550060
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The journal of sexual medicine.
2019 11; 16(11):1741-1748. doi:
10.1016/j.jsxm.2019.08.013
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Journal of veterinary pharmacology and therapeutics.
2019 Nov; 42(6):665-672. doi:
10.1111/jvp.12805
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Journal of clinical pharmacology.
2019 11; 59(11):1477-1484. doi:
10.1002/jcph.1447
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The Journal of sports medicine and physical fitness.
2019 Mar; 59(3):489-495. doi:
10.23736/s0022-4707.18.08366-4
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Cytotherapy.
2018 12; 20(12):1445-1458. doi:
10.1016/j.jcyt.2018.09.005
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The Journal of sports medicine and physical fitness.
2018 Nov; 58(11):1681-1687. doi:
10.23736/s0022-4707.17.06763-9
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Drug testing and analysis.
2018 Apr; 10(4):723-730. doi:
10.1002/dta.2301
. [PMID: 28901724] - S Karbasi, M Zaeemi, M Mohri, A Rashidlamir, Z Moosavi. Effects of testosterone enanthate and resistance training on myocardium in Wistar rats; clinical and anatomical pathology.
Andrologia.
2018 Apr; 50(3):. doi:
10.1111/and.12908
. [PMID: 29047154] - Yamina Zatra, Naouel Aknoun-Sail, Arezki Kheddache, Abdelouafi Benmouloud, Salima Charallah, Elara N Moudilou, Jean-Marie Exbrayat, Farida Khammar, Zaina Amirat. Seasonal changes in plasma testosterone and cortisol suggest an androgen mediated regulation of the pituitary adrenal axis in the Tarabul's gerbil Gerbillus tarabuli (Thomas, 1902).
General and comparative endocrinology.
2018 03; 258(?):173-183. doi:
10.1016/j.ygcen.2017.08.012
. [PMID: 28811197] - M Zarei, M Zaeemi, A Rashidlamir. Effects of testosterone enanthate treatment in conjunction with resistance training on thyroid hormones and lipid profile in male Wistar rats.
Andrologia.
2018 Mar; 50(2):. doi:
10.1111/and.12862
. [PMID: 28736926] - K Shigehara, H Konaka, T Nohara, K Izumi, Y Kitagawa, Y Kadono, T Iwamoto, E Koh, A Mizokami, M Namiki. Effects of testosterone replacement therapy on metabolic syndrome among Japanese hypogonadal men: A subanalysis of a prospective randomised controlled trial (EARTH study).
Andrologia.
2018 Feb; 50(1):. doi:
10.1111/and.12815
. [PMID: 28497534] - Ashraf B Abdel-Naim, Thikryat Neamatallah, Basma G Eid, Ahmed Esmat, Abdulmohsin J Alamoudi, Gamal S Abd El-Aziz, Osama M Ashour. 2-Methoxyestradiol Attenuates Testosterone-Induced Benign Prostate Hyperplasia in Rats through Inhibition of HIF-1α/TGF-β/Smad2 Axis.
Oxidative medicine and cellular longevity.
2018; 2018(?):4389484. doi:
10.1155/2018/4389484
. [PMID: 30154949] - Jovana Joksimović, Dragica Selaković, Vladimir Jakovljević, Vladimir Mihailović, Jelena Katanić, Tatjana Boroja, Gvozden Rosić. Alterations of the oxidative status in rat hippocampus and prodepressant effect of chronic testosterone enanthate administration.
Molecular and cellular biochemistry.
2017 Sep; 433(1-2):41-50. doi:
10.1007/s11010-017-3014-0
. [PMID: 28342008] - T Gagliano-Jucá, E R Tang, S Bhasin, K M Pencina, S Anderson, H Jara, Z Li, K Melamud, S L Coleman, A Aakil, R R Almeida, G Huang, T G Travison, T W Storer, S Basaria. Effects of testosterone administration (and its 5-alpha-reduction) on parenchymal organ volumes in healthy young men: findings from a dose-response trial.
Andrology.
2017 Sep; 5(5):889-897. doi:
10.1111/andr.12392
. [PMID: 28704587] - Meng-Xia Ni, Hui-Jie Zhi, Shuai-Mei Liu, Pei-Ran Zhu, Jing Zhang, Qiu-Yue Wu, Wei-Jun Jiang, Mao-Mao Yu, Wei-Wei Li, Jin Cao, Hao-Qin Xu, Xin-Yi Xia, Xiao-Feng Xu, Liang Shi. [Single nucleotide polymorphism of the TP53 gene is not correlated with male infertility].
Zhonghua nan ke xue = National journal of andrology.
2017 Feb; 23(2):142-146. doi:
NULL
. [PMID: 29658252] - Kouji Izumi, Kazuyoshi Shigehara, Takahiro Nohara, Kazutaka Narimoto, Yoshifumi Kadono, Shigeki Nanjo, Tadaaki Yamada, Koushiro Ohtsubo, Seiji Yano, Atsushi Mizokami. Androgen replacement therapy for cancer-related symptoms in male advanced cancer patients: study protocol for a randomised prospective trial (ARTFORM study).
The journal of medical investigation : JMI.
2017; 64(3.4):202-204. doi:
10.2152/jmi.64.202
. [PMID: 28954982] - Kok-Yong Chin, Dhivakaran Gengatharan, Fadlin Sakina Mohd Nasru, Rehan Amalia Khairussam, Sherlyn Lai Hui Ern, Siti Aina Wahidah Aminuddin, Soelaiman Ima-Nirwana. The Effects of Annatto Tocotrienol on Bone Biomechanical Strength and Bone Calcium Content in an Animal Model of Osteoporosis Due to Testosterone Deficiency.
Nutrients.
2016 Dec; 8(12):. doi:
10.3390/nu8120808
. [PMID: 27983628] - Lucía Demaldé, Mariana Lopez Merlo, Rosario Vercellini, Claudio G Barbeito, Patricia Fernandez, Cristina Gobello. Disrupting effect of androgens in postnatal female domestic cats.
Animal reproduction science.
2016 Aug; 171(?):65-71. doi:
10.1016/j.anireprosci.2016.05.015
. [PMID: 27305841] - Robert Krysiak, Wojciech Gilowski, Bogusław Okopień. The effect of testosterone on cardiovascular risk factors in men with type 2 diabetes and late-onset hypogonadism treated with metformin or glimepiride.
Pharmacological reports : PR.
2016 Feb; 68(1):75-9. doi:
10.1016/j.pharep.2015.06.003
. [PMID: 26721356] - Robert Krysiak, Beata Kowalska, Witold Szkróbka, Bogusław Okopień. A neutral effect of testosterone therapy on macroprolactin content in men with macroprolactinemia and late-onset hypogonadism.
Pharmacological reports : PR.
2016 Feb; 68(1):139-43. doi:
10.1016/j.pharep.2015.08.003
. [PMID: 26721365] - Robert Krysiak, Wojciech Gilowski, Bogusław Okopień. The effect of testosterone on cardiometabolic risk factors in atorvastatin-treated men with late-onset hypogonadism.
Pharmacological reports : PR.
2016 Feb; 68(1):196-200. doi:
10.1016/j.pharep.2015.08.009
. [PMID: 26721373] - B Nchegang, C Mezui, F Longo, Z E Nkwengoua, A P Amang, P V Tan. Effects of the Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Sexual Behavior in Normal Male Rats.
BioMed research international.
2016; 2016(?):9706429. doi:
10.1155/2016/9706429
. [PMID: 27525283] - Jed Kaminetsky, Jonathan S Jaffe, Ronald S Swerdloff. Pharmacokinetic Profile of Subcutaneous Testosterone Enanthate Delivered via a Novel, Prefilled Single-Use Autoinjector: A Phase II Study.
Sexual medicine.
2015 Dec; 3(4):269-79. doi:
10.1002/sm2.80
. [PMID: 26797061] - Emmanuel Strahm, Jenny E Mullen, Nina Gårevik, Magnus Ericsson, Jenny J Schulze, Anders Rane, Lena Ekström. Dose-dependent testosterone sensitivity of the steroidal passport and GC-C-IRMS analysis in relation to the UGT2B17 deletion polymorphism.
Drug testing and analysis.
2015 Nov; 7(11-12):1063-70. doi:
10.1002/dta.1841
. [PMID: 26198073] - V Camozzi, G Bonanni, A Frigo, M Piccolo, S Ferasin, M Zaninotto, M Boscaro, G Luisetto. Effect of a single injection of testosterone enanthate on 17β estradiol and bone turnover markers in hypogonadal male patients.
Journal of endocrinological investigation.
2015 Apr; 38(4):389-97. doi:
10.1007/s40618-014-0183-5
. [PMID: 25319469] - Luke A Beggs, Joshua F Yarrow, Christine F Conover, John R Meuleman, Darren T Beck, Matthew Morrow, Baiming Zou, Jonathan J Shuster, Stephen E Borst. Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone.
American journal of physiology. Endocrinology and metabolism.
2014 Sep; 307(5):E456-61. doi:
10.1152/ajpendo.00184.2014
. [PMID: 25074984] - Cristine Skogastierna, Maja Hotzen, Anders Rane, Lena Ekström. A supraphysiological dose of testosterone induces nitric oxide production and oxidative stress.
European journal of preventive cardiology.
2014 Aug; 21(8):1049-54. doi:
10.1177/2047487313481755
. [PMID: 23471592] - Linda M Dairiki Shortliffe, Youxin Ye, Barry Behr, Bingyin Wang. Testosterone changes bladder and kidney structure in juvenile male rats.
The Journal of urology.
2014 Jun; 191(6):1913-9. doi:
10.1016/j.juro.2014.01.012
. [PMID: 24518779] - Animesh N Sharma, Paul Aoun, Jean R Wigham, Suanne M Weist, Johannes D Veldhuis. Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsatile ACTH secretion and ACTH approximate entropy in unstressed older men and women.
American journal of physiology. Regulatory, integrative and comparative physiology.
2014 May; 306(9):R627-35. doi:
10.1152/ajpregu.00551.2013
. [PMID: 24573184] - Stephen E Borst, Joshua F Yarrow, Christine F Conover, Unyime Nseyo, John R Meuleman, Judyta A Lipinska, Randy W Braith, Darren T Beck, Jeffrey S Martin, Matthew Morrow, Shirley Roessner, Luke A Beggs, Sean C McCoy, Darryl F Cannady, Jonathan J Shuster. Musculoskeletal and prostate effects of combined testosterone and finasteride administration in older hypogonadal men: a randomized, controlled trial.
American journal of physiology. Endocrinology and metabolism.
2014 Feb; 306(4):E433-42. doi:
10.1152/ajpendo.00592.2013
. [PMID: 24326421] - Christian K Roberts, Brian H Chen, Sandeep Pruthi, Martin L Lee. Effects of varying doses of testosterone on atherogenic markers in healthy younger and older men.
American journal of physiology. Regulatory, integrative and comparative physiology.
2014 Jan; 306(2):R118-23. doi:
10.1152/ajpregu.00372.2013
. [PMID: 24305063] - Stephen E Borst, Joshua F Yarrow, Carmen Fernandez, Christine F Conover, Fan Ye, John R Meuleman, Matthew Morrow, Baiming Zou, Jonathan J Shuster. Cognitive effects of testosterone and finasteride administration in older hypogonadal men.
Clinical interventions in aging.
2014; 9(?):1327-33. doi:
10.2147/cia.s61760
. [PMID: 25143719] - Adam Zając, Michał Wilk, Teresa Socha, Adam Maszczyk, Jakub Chycki. Effects of growth hormone and testosterone therapy on aerobic and anaerobic fitness, body composition and lipoprotein profile in middle-aged men.
Annals of agricultural and environmental medicine : AAEM.
2014; 21(1):156-60. doi:
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Clinical interventions in aging.
2014; 9(?):1247-59. doi:
10.2147/cia.s67016
. [PMID: 25120355] - Kazunari Nohara, Suhuan Liu, Matthew S Meyers, Aurélie Waget, Mathieu Ferron, Gérard Karsenty, Rémy Burcelin, Franck Mauvais-Jarvis. Developmental androgen excess disrupts reproduction and energy homeostasis in adult male mice.
The Journal of endocrinology.
2013 Dec; 219(3):259-68. doi:
10.1530/joe-13-0230
. [PMID: 24084835] - Masato Okano, Toshihiko Ueda, Yasunori Nishitani, Hiroko Kano, Ayako Ikekita, Shinji Kageyama. UDP-glucuronosyltransferase 2B17 genotyping in Japanese athletes and evaluation of the current sports drug testing for detecting testosterone misuse.
Drug testing and analysis.
2013 Mar; 5(3):166-81. doi:
10.1002/dta.1394
. [PMID: 22887913] - Lena Ekström, Luca Cevenini, Elisa Michelini, Jenny Schulze, John-Olof Thörngren, Alain Belanger, Chantal Guillemette, Mats Garle, Aldo Roda, Anders Rane. Testosterone challenge and androgen receptor activity in relation to UGT2B17 genotypes.
European journal of clinical investigation.
2013 Mar; 43(3):248-55. doi:
10.1111/eci.12037
. [PMID: 23294483] - J W Kim, M M Oh, M G Park, J Y Park, J H Bae, J J Kim, D G Moon. Combination therapy of testosterone enanthate and tadalafil on PDE5 inhibitor non-reponders with severe and intermediate testosterone deficiency.
International journal of impotence research.
2013 Jan; 25(1):29-33. doi:
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. [PMID: 22971615] - Hiroaki Kurahashi, Masami Watanabe, Morito Sugimoto, Yuichi Ariyoshi, Sabina Mahmood, Motoo Araki, Kazushi Ishii, Yasutomo Nasu, Atsushi Nagai, Hiromi Kumon. Testosterone replacement elevates the serum uric acid levels in patients with female to male gender identity disorder.
Endocrine journal.
2013; 60(12):1321-7. doi:
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British journal of clinical pharmacology.
2012 Jul; 74(1):3-15. doi:
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Andrologia.
2012 May; 44 Suppl 1(?):362-9. doi:
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Andrologia.
2012 May; 44 Suppl 1(?):312-22. doi:
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American journal of physiology. Cell physiology.
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Substance abuse treatment, prevention, and policy.
2012 Mar; 7(?):12. doi:
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JAMA.
2012 Mar; 307(9):931-9. doi:
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Der Anaesthesist.
2012 Mar; 61(3):224-6, 228. doi:
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The journal of sexual medicine.
2012 Mar; 9(3):873-86. doi:
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Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):193496. doi:
10.1155/2012/193496
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International journal of endocrinology.
2012; 2012(?):625434. doi:
10.1155/2012/625434
. [PMID: 22505891] - Jenny J Schulze, John-Olof Thörngren, Mats Garle, Lena Ekström, Anders Rane. Androgen sulfation in healthy UDP-glucuronosyl transferase 2B17 enzyme-deficient men.
The Journal of clinical endocrinology and metabolism.
2011 Nov; 96(11):3440-7. doi:
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Reproductive biology and endocrinology : RB&E.
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Fertility and sterility.
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Pharmacogenetics and genomics.
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BJU international.
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BMC pediatrics.
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American journal of physiology. Endocrinology and metabolism.
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International journal of Ayurveda research.
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The Journal of clinical endocrinology and metabolism.
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Neuroscience letters.
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International journal of clinical practice.
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General and comparative endocrinology.
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European journal of endocrinology.
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Metabolism: clinical and experimental.
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International journal of endocrinology.
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The Journal of clinical endocrinology and metabolism.
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BMC pediatrics.
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Nutrition research and practice.
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Pediatric surgery international.
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American journal of physiology. Endocrinology and metabolism.
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BMC endocrine disorders.
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American journal of physiology. Endocrinology and metabolism.
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The Journal of steroid biochemistry and molecular biology.
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