Dichloroisoproterenol (BioDeep_00000178221)

   

human metabolite blood metabolite


代谢物信息卡片


1-(3,4-dichlorophenyl)-2-[(propan-2-yl)amino]ethan-1-ol

化学式: C11H15Cl2NO (247.0531)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 71.43%

分子结构信息

SMILES: CC(C)NCC(C1=CC(=C(C=C1)Cl)Cl)O
InChI: InChI=1S/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 GRP, MYLK, PLA2G12A
Peripheral membrane protein 1 ACHE
Endosome membrane 1 ADRB2
Endoplasmic reticulum membrane 1 SPP1
Nucleus 3 ACHE, ADRB2, PLCZ1
cytosol 4 AVP, LIPE, MYLK, PLCZ1
dendrite 1 AVP
nucleoplasm 1 PLCZ1
Cell membrane 5 ACHE, ADRB2, ADRB3, LIPE, SPP1
Cleavage furrow 1 MYLK
lamellipodium 1 MYLK
Multi-pass membrane protein 3 ADRB2, ADRB3, SPP1
Synapse 3 ACHE, MYLK, TAC1
cell surface 1 ACHE
Golgi apparatus 3 ACHE, ADRB2, SPP1
lysosomal membrane 1 GAA
neuromuscular junction 1 ACHE
neuronal cell body 1 TAC1
Cytoplasm, cytosol 1 LIPE
Lysosome 2 ADRB2, GAA
endosome 1 ADRB2
plasma membrane 8 ACHE, ADRB2, ADRB3, EDNRA, GAA, GCG, MYLK, SPP1
Membrane 4 ACHE, ADRB2, GAA, LIPE
apical plasma membrane 1 ADRB2
axon 1 TAC1
caveola 1 LIPE
extracellular exosome 2 GAA, SPP1
Lysosome membrane 1 GAA
extracellular space 6 ACHE, AVP, GCG, GRP, SPP1, TAC1
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 3 ACHE, PLCZ1, SPP1
intracellular membrane-bounded organelle 1 GAA
pronucleus 1 PLCZ1
Secreted 7 ACHE, AVP, GAA, GCG, GRP, PLA2G12A, SPP1
extracellular region 8 ACHE, AVP, GAA, GCG, GRP, PLA2G12A, SPP1, TAC1
Extracellular side 1 ACHE
Secreted, extracellular space, extracellular matrix 1 GRP
actin cytoskeleton 1 MYLK
nucleolus 1 PLCZ1
Early endosome 1 ADRB2
Cell projection, lamellipodium 1 MYLK
Cytoplasm, perinuclear region 1 PLCZ1
extracellular matrix 1 GRP
basement membrane 1 ACHE
secretory granule 1 AVP
receptor complex 2 ADRB2, ADRB3
Cell projection, neuron projection 1 GRP
neuron projection 1 GRP
cell projection 1 SPP1
Lipid-anchor, GPI-anchor 1 ACHE
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
tertiary granule membrane 1 GAA
side of membrane 1 ACHE
stress fiber 1 MYLK
secretory granule lumen 2 GCG, GRP
endoplasmic reticulum lumen 2 GCG, SPP1
azurophil granule membrane 1 GAA
neuronal dense core vesicle 3 ADRB2, AVP, GRP
clathrin-coated endocytic vesicle membrane 2 ADRB2, AVP
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
[Glucagon-like peptide 1]: Secreted 1 GCG
sperm head 1 PLCZ1
Cytoplasmic vesicle, secretory vesicle lumen 1 GRP
autolysosome lumen 1 GAA
[Isoform H]: Cell membrane 1 ACHE


文献列表

  • P E Ryals, X Yang. Effects of dichloroisoproterenol on macromolecular synthesis and differentiation in Tetrahymena vorax. The Journal of eukaryotic microbiology. 1997 Jan; 44(1):43-5. doi: 10.1111/j.1550-7408.1997.tb05689.x. [PMID: 9172831]
  • C R BOSHART, L WILL, A PIRRE, I RINGLER. THE EFFECTS OF RESERPINE,GUANETHIDINE AND OTHER AUTONOMIC DRUGS ON FREE FATTY ACID MOBILIZATION INDUCED BY PHENTOLAMINE. The Journal of pharmacology and experimental therapeutics. 1965 Jul; 149(?):57-64. doi: ". [PMID: 14334292]
  • R BRUS, M CHRUSCIEL, T L CHRUSCIEL, A PLECH. SYMPATHOLYTIC DRUGS AND HYPERLIPAEMIA INDUCED IN RATS BY INTRAPERITONEAL INJECTIONS OF SURFACE-ACTIVE AGENT. British journal of pharmacology and chemotherapy. 1964 Dec; 23(?):449-54. doi: 10.1111/j.1476-5381.1964.tb01602.x. [PMID: 14256806]
  • J P GILMORE, N S SKINNER. STUDIES ON THE SYSTEMIC EFFECTS OF -PAMCL. Archives internationales de pharmacodynamie et de therapie. 1964 Oct; 151(?):503-9. doi: NULL. [PMID: 14228063]
  • A V GOODYER, M J GOODKIND, E J STANLEY. THE EFFECTS OF ABNORMAL CONCENTRATIONS OF THE SERUM ELECTROLYTES ON LEFT VENTRICULAR FUNCTION IN THE INTACT ANIMAL. American heart journal. 1964 Jun; 67(?):779-91. doi: 10.1016/0002-8703(64)90179-6. [PMID: 14171995]
  • R A SALVADOR, K I COLVILLE, S A APRIL, J J BURNS. INHIBITION OF LIPID MOBILIZATION BY N-ISOPROPYL METHOXAMINE (B.W. 61-43). The Journal of pharmacology and experimental therapeutics. 1964 May; 144(?):172-80. doi: ". [PMID: 14183428]
  • D SCHUSTEROVA, D KRCIKOVA, E MUEHLBACHOVA, S HYNIE, M WENKE. INFLUENCE OF SOME NEW BETA-SYMPATHOTROPIC AGENTS ON LIPID MOBILIZATION IN VITRO. International journal of neuropharmacology. 1964 Apr; 3(?):129-34. doi: 10.1016/0028-3908(64)90056-5. [PMID: 14334588]
  • J FARRANT, J A HARVEY, J N PENNEFATHER. THE INFLUENCE OF PHENOXYBENZAMINE ON THE STORAGE OF NORADRENALINE IN RAT AND CAT TISSUES. British journal of pharmacology and chemotherapy. 1964 Feb; 22(?):104-12. doi: 10.1111/j.1476-5381.1964.tb01547.x. [PMID: 14126039]
  • D RUDMAN, L A GARCIA, S J BROWN, M F MALKIN, W PERL. DOSE-RESPONSE CURVES FOR THE ADIPOKINETIC ACTION OF AROMATIC AMINES AND ADRENOCORTICOTROPIN UPON THE ISOLATED ADIPOSE TISSUE OF THE HAMSTER. Journal of lipid research. 1964 Jan; 5(?):28-37. doi: 10.1016/s0022-2275(20)40256-1. [PMID: 14173325]
  • J ASHMORE, J E PRESTON, W C LOVE. Effects of dichloroisoproterenol on blood sugar and plasma free fatty acids. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1962 Feb; 109(?):291-4. doi: 10.3181/00379727-109-27182. [PMID: 13862858]