Etorphine (BioDeep_00000171772)

   

human metabolite blood metabolite


代谢物信息卡片


19-(2-hydroxypentan-2-yl)-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11,16-tetraen-11-ol

化学式: C25H33NO4 (411.2409)
中文名称: 乙烯啡
谱图信息: 最多检出来源 Homo sapiens(blood) 98.54%

分子结构信息

SMILES: CCCC(C)(C1CC23C=CC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)C)OC)O
InChI: InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3

描述信息

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics

同义名列表

4 个代谢物同义名

19-(2-hydroxypentan-2-yl)-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11,16-tetraen-11-ol; Ethorphine; Etorphine; Etorphine



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 CNR1, DNM2, GRK2, HTR4, POMC, PRKX, SAG, TRIM13
Peripheral membrane protein 2 DNM2, SAG
Endosome membrane 1 HTR4
Endoplasmic reticulum membrane 1 TRIM13
Nucleus 3 PLCZ1, PRKX, SAG
cytosol 7 DNM2, GRK2, GYPA, PLCZ1, PRKCQ, SAG, SST
dendrite 4 HTR4, OPRM1, PDYN, PNOC
centrosome 1 DNM2
nucleoplasm 4 GYPA, PLCZ1, PRKX, SAG
Cell membrane 8 CNR1, GPRC5A, GRK2, GYPA, HTR4, OPRD1, OPRL1, OPRM1
Cell projection, axon 2 CNR1, OPRM1
Multi-pass membrane protein 6 CNR1, GPRC5A, HTR4, OPRD1, OPRL1, OPRM1
Synapse 6 DNM2, GRK2, HTR4, OPRM1, PDYN, PNOC
cell junction 1 DNM2
glutamatergic synapse 2 CNR1, HTR4
Golgi apparatus 2 DNM2, OPRM1
Golgi membrane 2 DNM2, INS
growth cone 1 CNR1
neuronal cell body 3 PDYN, PNOC, SST
postsynapse 2 GRK2, HTR4
presynaptic membrane 2 CNR1, OPRD1
Presynapse 3 CNR1, DNM2, GRK2
endosome 3 DNM2, HTR4, OPRM1
plasma membrane 12 CNR1, DNM2, GPRC5A, GRK2, GYPA, HTR4, OPRD1, OPRL1, OPRM1, PDYN, PNOC, PRKCQ
synaptic vesicle membrane 1 OPRD1
Membrane 6 GRK2, GYPA, HTR4, OPRD1, OPRM1, SAG
axon 3 CCK, CNR1, OPRM1
extracellular exosome 2 DNM2, GPRC5A
endoplasmic reticulum 1 OPRM1
extracellular space 4 CCK, INS, POMC, SST
perinuclear region of cytoplasm 1 PLCZ1
intracellular membrane-bounded organelle 1 GPRC5A
postsynaptic density 1 DNM2
pronucleus 1 PLCZ1
Single-pass type I membrane protein 1 GYPA
Secreted 6 CCK, INS, PDYN, PNOC, POMC, SST
extracellular region 6 CCK, INS, PDYN, PNOC, POMC, SST
Mitochondrion outer membrane 1 CNR1
Single-pass membrane protein 2 GYPA, TRIM13
mitochondrial outer membrane 1 CNR1
hippocampal mossy fiber to CA3 synapse 1 PDYN
centriolar satellite 1 PRKCQ
photoreceptor inner segment 1 SAG
photoreceptor outer segment 1 SAG
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 DNM2
actin cytoskeleton 1 CNR1
perikaryon 1 OPRM1
cytoplasmic vesicle 1 OPRL1
nucleolus 2 GPRC5A, PLCZ1
midbody 1 DNM2
Membrane, clathrin-coated pit 1 DNM2
clathrin-coated pit 1 DNM2
recycling endosome 1 DNM2
vesicle 1 GPRC5A
postsynaptic membrane 1 DNM2
Cytoplasm, perinuclear region 1 PLCZ1
Membrane raft 1 CNR1
Cytoplasm, cytoskeleton 1 DNM2
focal adhesion 1 DNM2
microtubule 1 DNM2
GABA-ergic synapse 2 CNR1, SST
secretory granule 1 POMC
receptor complex 1 GPRC5A
neuron projection 4 DNM2, OPRD1, OPRL1, OPRM1
cilium 1 GRK2
Cytoplasmic vesicle, phagosome membrane 1 DNM2
Cell projection, phagocytic cup 1 DNM2
phagocytic cup 1 DNM2
phagocytic vesicle membrane 1 DNM2
Cell projection, podosome 1 DNM2
podosome 1 DNM2
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 1 DNM2
centriole 1 DNM2
Cell projection, cilium, photoreceptor outer segment 1 SAG
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 GPRC5A
Cell projection, dendrite 1 OPRM1
clathrin-coated vesicle 1 DNM2
synaptic membrane 1 PNOC
secretory granule lumen 2 INS, POMC
endoplasmic reticulum quality control compartment 1 TRIM13
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
axon terminus 3 OPRD1, PDYN, PNOC
endocytic vesicle membrane 1 DNM2
Cytoplasmic vesicle, clathrin-coated vesicle 1 DNM2
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Cul5-RING ubiquitin ligase complex 1 SAG
postsynaptic density membrane 1 OPRD1
immunological synapse 1 PRKCQ
neuronal dense core vesicle 3 OPRD1, PDYN, SST
aggresome 1 PRKCQ
perinuclear endoplasmic reticulum 1 TRIM13
uropod 1 DNM2
Synapse, synaptosome 1 DNM2
dendrite membrane 1 OPRD1
Cell projection, uropodium 1 DNM2
ankyrin-1 complex 1 GYPA
sperm head 1 PLCZ1
cytoplasmic side of mitochondrial outer membrane 1 GRK2
[Isoform 12]: Cytoplasm 1 OPRM1
spine apparatus 1 OPRD1


文献列表

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