N-formylmethionine (BioDeep_00000001688)

 

Secondary id: BioDeep_00000400077, BioDeep_00000405932, BioDeep_00000408257

natural product human metabolite PANOMIX_OTCML-2023 Endogenous BioNovoGene_Lab2019


代谢物信息卡片


(2S)-2-(Formylamino)-4-(methylthio)butanoic acid

化学式: C6H11NO3S (177.046)
中文名称: N-甲醯甲硫胺酸, N-甲酰基-DL, N-甲酰基-L-蛋氨酸, N-甲酰甲硫氨酸
谱图信息: 最多检出来源 Homo sapiens(feces) 23.64%

Reviewed

Last reviewed on 2024-07-10.

Cite this Page

N-formylmethionine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/n-formyl-l-methionine (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000001688). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CSCCC(C(=O)O)NC=O
InChI: InChI=1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)

描述信息

N-formyl-L-methionine is a L-methionine derivative in which one of the hydrogens attached to the nitrogen is replaced by a formyl group. It has a role as a metabolite. It is a proteinogenic amino acid, a N-formyl amino acid and a L-methionine derivative. It is a conjugate acid of a N-formyl-L-methioninate. N-Formyl-L-methionine belongs to the class of organic compounds known as methionine and derivatives. Methionine and derivatives are compounds containing methionine or a derivative thereof resulting from reaction of methionine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. N-Formyl-L-methionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl-tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eukaryotic cells.
Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells. [HMDB]

For-Met-OH is an endogenous metabolite.

同义名列表

18 个代谢物同义名

(2S)-2-(Formylamino)-4-(methylthio)butanoic acid; (2S)-2-formamido-4-(methylsulfanyl)butanoic acid; (2S)-2-(Formylamino)-4-(methylthio)butanoate; 2-formamido-4-methylsulfanylbutanoic acid; N-Formyl-DL-methionine; N-Formyl-L-methionine; Formylmethionine, N; Formyl-L-methionine; N-FORMYL-METHIONINE; N-Formylmethionine; N Formylmethionine; Formyl-methionine; formylmethionine; For-DL-Met-OH; For-Met-OH; FMET; N-Formyl-methionine; N-Formylmethionine



数据库引用编号

35 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ELANE, FPR1, FPR2, GTPBP4, MAPK14, MARS1, MTIF2
Nucleus 3 GTPBP4, MAPK14, MPO
cytosol 5 ELANE, GOLPH3, GTPBP4, MAPK14, MARS1
phagocytic vesicle 1 ELANE
trans-Golgi network 1 GOLPH3
nucleoplasm 4 GTPBP4, MAPK14, MPO, MTIF2
Cell membrane 7 C5AR1, CD8A, FPR1, FPR2, GOLPH3, ITGAM, TNF
Multi-pass membrane protein 3 C5AR1, FPR1, FPR2
cell surface 3 ELANE, ITGAM, TNF
glutamatergic synapse 1 MAPK14
Golgi apparatus 1 GOLPH3
Golgi membrane 1 GOLPH3
neuronal cell body 1 TNF
Cytoplasm, cytosol 1 MARS1
Lysosome 1 MPO
endosome 1 GOLPH3
plasma membrane 9 C5AR1, CD8A, F2, FPR1, FPR2, GOLPH3, IGHE, ITGAM, TNF
Membrane 6 FPR1, FPR2, GOLPH3, GTPBP4, ITGAM, MARS1
basolateral plasma membrane 1 C5AR1
extracellular exosome 6 ELANE, F2, ITGAM, LYZ, MARS1, MPO
extracellular space 9 ELANE, F2, IGHE, IL10, IL6, ITGAM, LYZ, MPO, TNF
perinuclear region of cytoplasm 1 GTPBP4
mitochondrion 5 GOLPH3, MAPK14, MTFMT, MTIF2, MTIF3
intracellular membrane-bounded organelle 2 GOLPH3, MPO
Single-pass type I membrane protein 3 CD8A, IGHE, ITGAM
Secreted 3 F2, IL10, IL6
extracellular region 10 CD8A, ELANE, F2, IGHE, IL10, IL6, LYZ, MAPK14, MPO, TNF
[Isoform 2]: Secreted 1 CD8A
nuclear membrane 1 GTPBP4
external side of plasma membrane 3 CD8A, ITGAM, TNF
cytoplasmic vesicle 1 C5AR1
nucleolus 2 GTPBP4, MARS1
apical part of cell 1 C5AR1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 2 ITGAM, TNF
mitochondrial intermembrane space 1 GOLPH3
collagen-containing extracellular matrix 2 ELANE, F2
secretory granule 2 ELANE, MPO
nuclear speck 1 MAPK14
receptor complex 1 CD8A
IgE immunoglobulin complex 1 IGHE
phagocytic cup 1 TNF
Nucleus, nucleolus 2 GTPBP4, MARS1
spindle pole 1 MAPK14
blood microparticle 1 F2
[Isoform 2]: Cell membrane 1 IGHE
specific granule membrane 2 FPR2, ITGAM
tertiary granule membrane 2 FPR2, ITGAM
Golgi cisterna membrane 1 GOLPH3
azurophil granule 1 MPO
plasma membrane raft 2 CD8A, ITGAM
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 1 MAPK14
secretory granule membrane 2 C5AR1, FPR1
Golgi lumen 1 F2
endoplasmic reticulum lumen 2 F2, IL6
transcription repressor complex 1 ELANE
specific granule lumen 2 ELANE, LYZ
tertiary granule lumen 1 LYZ
azurophil granule membrane 1 FPR1
azurophil granule lumen 3 ELANE, LYZ, MPO
Golgi cisterna 1 GOLPH3
phagocytic vesicle lumen 1 MPO
ficolin-1-rich granule membrane 2 FPR1, FPR2
[Isoform 1]: Cell membrane 1 CD8A
aminoacyl-tRNA synthetase multienzyme complex 1 MARS1
Cytoplasmic vesicle, phagosome 1 ELANE
integrin complex 1 ITGAM
[Isoform 3]: Cell membrane 1 IGHE
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD8A
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
integrin alphaM-beta2 complex 1 ITGAM
interleukin-6 receptor complex 1 IL6
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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