N-Formylmethionine (BioDeep_00000405932)

Main id: BioDeep_00000001688

 

PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


N-Formyl-L-methionine

化学式: C6H11NO3S (177.0459616)
中文名称: N-甲醯甲硫胺酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CSCCC(C(=O)O)NC=O
InChI: InChI=1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1

描述信息

A L-methionine derivative in which one of the hydrogens attached to the nitrogen is replaced by a formyl group.
For-Met-OH is an endogenous metabolite.

同义名列表

4 个代谢物同义名

N-Formyl-L-methionine; Formyl-L-methionine; N-Formylmethionine; For-Met-OH



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Ying Feng, Shannon K Chang, Daniel A Portnoy. The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine. mBio. 2023 Sep; ?(?):e0107423. doi: 10.1128/mbio.01074-23. [PMID: 37695058]
  • Ravindran K Veena, Thekkuttuparambil A Ajith, Kainoor K Janardhanan, Francis Antonawich. Poly-MVA attenuates 7,12- dimethylbenz[a]anthracene initiated and croton oil promoted skin papilloma formation on mice skin. Journal of experimental therapeutics & oncology. 2017 Sep; 11(2):125-132. doi: ". [PMID: 28976135]
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  • Sunok Moon, Carmela Giglione, Dong-Yeon Lee, Suyoung An, Dong-Hoon Jeong, Thierry Meinnel, Gynheung An. Rice peptide deformylase PDF1B is crucial for development of chloroplasts. Plant & cell physiology. 2008 Oct; 49(10):1536-46. doi: 10.1093/pcp/pcn121. [PMID: 18718933]
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  • CongHui You, HongYan Lu, Agnieszka Sekowska, Gang Fang, YiPing Wang, Anne-Marie Gilles, Antoine Danchin. The two authentic methionine aminopeptidase genes are differentially expressed in Bacillus subtilis. BMC microbiology. 2005 Oct; 5(?):57. doi: 10.1186/1471-2180-5-57. [PMID: 16207374]
  • Julian P Whitelegge, Huamin Zhang, Rodrigo Aguilera, Ross M Taylor, William A Cramer. Full subunit coverage liquid chromatography electrospray ionization mass spectrometry (LCMS+) of an oligomeric membrane protein: cytochrome b(6)f complex from spinach and the cyanobacterium Mastigocladus laminosus. Molecular & cellular proteomics : MCP. 2002 Oct; 1(10):816-27. doi: 10.1074/mcp.m200045-mcp200. [PMID: 12438564]
  • C Giglione, T Meinnel. Organellar peptide deformylases: universality of the N-terminal methionine cleavage mechanism. Trends in plant science. 2001 Dec; 6(12):566-72. doi: 10.1016/s1360-1385(01)02151-3. [PMID: 11738381]
  • M Tohkin, N Morishima, T Iiri, K Takahashi, M Ui, T Katada. Interaction of guanine-nucleotide-binding regulatory proteins with chemotactic peptide receptors in differentiated human leukemic HL-60 cells. European journal of biochemistry. 1991 Jan; 195(2):527-33. doi: 10.1111/j.1432-1033.1991.tb15733.x. [PMID: 1847687]
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  • R M Palmer, J A Salmon. Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187. Immunology. 1983 Sep; 50(1):65-73. doi: . [PMID: 6309653]
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  • J P Bennett, S Cockcroft, A H Caswell, B D Gomperts. Plasma-membrane location of phosphatidylinositol hydrolysis in rabbit neutrophils stimulated with formylmethionyl-leucylphenylalanine. The Biochemical journal. 1982 Dec; 208(3):801-8. doi: 10.1042/bj2080801. [PMID: 7165735]
  • H D Perez, R Ong, K Khanna, D Banda, I M Goldstein. Wheat germ agglutinin specifically inhibits formyl peptide-induced polymorphonuclear leukocyte chemotaxis. Journal of immunology (Baltimore, Md. : 1950). 1982 Dec; 129(6):2718-24. doi: NULL. [PMID: 6897258]
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  • W M Mackin, C K Huang, E L Becker. The formylpeptide chemotactic receptor on rabbit peritoneal neutrophils. I. Evidence for two binding sites with different affinities. Journal of immunology (Baltimore, Md. : 1950). 1982 Oct; 129(4):1608-11. doi: NULL. [PMID: 6286772]
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  • J O Shaw, I Brodersen, R M Lyons. Extra- and intracellular Ca2+ requirements for lysosomal enzyme secretion in human neutrophils. Agents and actions. 1982 Jul; 12(3):328-32. doi: 10.1007/bf01965398. [PMID: 6814207]
  • A Naef, E R Waelti, R Glueck, M W Hess, H Keller. Enhancement of formylmethionyl-leucyl-phenylalanine-induced directional locomotion of human neutrophils by serum low-density lipoproteins. Immunology letters. 1982 Jul; 5(1):1-5. doi: 10.1016/0165-2478(82)90081-5. [PMID: 7118182]
  • B E Seligmann, M P Fletcher, J I Gallin. Adaptation of human neutrophil responsiveness to the chemoattractant N-formylmethionylleucylphenylalanine. Heterogeneity and/or negative cooperative interaction of receptors. The Journal of biological chemistry. 1982 Jun; 257(11):6280-6. doi: 10.1016/s0021-9258(20)65135-3. [PMID: 6281264]
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