16alpha-Hydroxytestosterone (BioDeep_00000010010)

   


代谢物信息卡片


16alpha,17beta-Dihydroxy-4-androsten-3-one

化学式: C19H28O3 (304.2038)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC12CCC(=O)C=C1CCC1C2CCC2(C)C(O)C(O)CC12
InChI: InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h9,13-17,21-22H,3-8,10H2,1-2H3



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ACE, AR, CYP1A1, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP2E1, CYP3A4, FAS
Peripheral membrane protein 6 CYP1A1, CYP1B1, CYP2B6, CYP2E1, FDXR, HSD17B6
Endoplasmic reticulum membrane 11 CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A7
Nucleus 1 AR
cytosol 2 AR, FAS
nuclear body 1 FAS
nucleoplasm 1 AR
Cell membrane 3 ACE, AGTR1, FAS
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 3 AGTR1, CYP19A1, DUOX1
cell surface 2 DUOX1, FAS
Golgi apparatus 1 FAS
mitochondrial inner membrane 3 CYP1A1, CYP2E1, FDXR
Lysosome 1 ACE
endosome 1 ACE
plasma membrane 8 ACE, AGTR1, AR, CYP2C19, CYP2C9, DUOX1, FAS, REN
Membrane 10 ACE, AGTR1, AR, CYP19A1, CYP1B1, CYP2D6, CYP3A4, DUOX1, FAS, REN
apical plasma membrane 1 DUOX1
extracellular exosome 2 ACE, FAS
Lumenal side 1 HSD17B6
endoplasmic reticulum 4 CYP19A1, CYP2D6, DUOX1, HSD17B6
extracellular space 3 ACE, IGF1, REN
mitochondrion 4 CYP1A1, CYP1B1, CYP2D6, FDXR
protein-containing complex 1 AR
intracellular membrane-bounded organelle 10 CYP1A1, CYP1A2, CYP1B1, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP2E1, CYP3A4, HSD17B6
Microsome membrane 11 CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2B6, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A7, HSD17B6
Single-pass type I membrane protein 2 ACE, FAS
Secreted 3 ACE, IGF1, REN
extracellular region 3 ACE, IGF1, REN
Single-pass membrane protein 1 CYP2D6
mitochondrial matrix 1 FDXR
external side of plasma membrane 2 ACE, FAS
apical part of cell 1 REN
Apical cell membrane 1 DUOX1
Mitochondrion inner membrane 3 CYP1A1, CYP2E1, FDXR
Membrane raft 1 FAS
nuclear speck 1 AR
chromatin 1 AR
cell leading edge 1 DUOX1
brush border membrane 1 ACE
sperm midpiece 1 ACE
Melanosome 1 FAS
basal plasma membrane 1 ACE
exocytic vesicle 1 IGF1
platelet alpha granule lumen 1 IGF1
CD95 death-inducing signaling complex 1 FAS
death-inducing signaling complex 1 FAS
[Isoform 1]: Cell membrane 1 FAS
NADPH oxidase complex 1 DUOX1
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
glycogen granule 1 FAS


文献列表

  • Wahid Ali Khan, Gaffar Sarwar Zaman, Sultan Alouffi, Mohd Wajid Ali Khan. Depression and its related parameters increased the production of autoantibodies against 16α-hydroxyestrone-albumin complex in systemic lupus erythematosus. International immunopharmacology. 2019 Jun; 71(?):215-223. doi: 10.1016/j.intimp.2019.03.036. [PMID: 30925322]
  • Jeffrey C Sivils, Tiffany M Ancrum, Lisa J Bain. LOSS of Mrp1 alters detoxification enzyme expression in a tissue- and hormonal-status-specific manner. Journal of applied toxicology : JAT. 2013 Aug; 33(8):766-73. doi: 10.1002/jat.2727. [PMID: 22522787]
  • T L Klug, E Bågeman, C Ingvar, C Rose, H Jernström. Moderate coffee and alcohol consumption improves the estrogen metabolite profile in adjuvant treated breast cancer patients: a pilot study comparing pre- and post-operative levels. Molecular genetics and metabolism. 2006 Dec; 89(4):381-9. doi: 10.1016/j.ymgme.2006.08.005. [PMID: 16978896]
  • M D Green, E M Oturu, T R Tephly. Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. Drug metabolism and disposition: the biological fate of chemicals. 1994 Sep; 22(5):799-805. doi: NULL. [PMID: 7835232]