γ-Fagarine (BioDeep_00000858852)

PANOMIX_OTCML-2023 Volatile Flavor Compounds

代谢物信息卡片

gamma-Fagarine

化学式: C13H11NO3 (229.0738896)
中文名称: 花椒碱
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC=CC2=C1N=C3C(=C2OC)C=CO3
InChI: InChI=1S/C13H11NO3/c1-15-10-5-3-4-8-11(10)14-13-9(6-7-17-13)12(8)16-2/h3-7H,1-2H3

描述信息

同义名列表

3 个代谢物同义名

gamma-Fagarine; γ-Fagarine; gamma-Fagarine

数据库引用编号

8 个数据库交叉引用编号

ChEBI: CHEBI:10562
KEGGdrug: D85115
PubChem: 107936
ChEMBL: CHEMBL252925
CAS: 524-15-2
KEGG: C10676
PubChem: 12859
KNApSAcK: 10562

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

54 个相关的物种来源信息

354485 - Acronychia pedunculata: 10.1016/S0031-9422(99)00039-4
2749840 - Asterolasia drummondii: 10.1021/NP50104A024
68535 - Casimiroa edulis: 10.1021/JF9802373
159034 - Clausena anisata: 10.1016/J.EJMECH.2011.10.047
1224762 - Clausena vestita: 10.1016/J.EJMECH.2011.10.047
298346 - Dictamnus albus:
714465 - Dictamnus dasycarpus: 10.1016/0165-7992(85)90054-5
1226072 - Drummondita calida:
282608 - Drummondita hassellii: 10.1016/0031-9422(92)80274-I
2820928 - Ertela trifolia:
1654694 - Esenbeckia febrifuga: 10.1016/J.PHYMED.2008.02.001
549402 - Esenbeckia grandiflora: 10.1016/J.FITOTE.2003.08.004
1081050 - Geijera salicifolia: 10.1071/CH9661991
650008 - Glycosmis citrifolia: 10.1016/0031-9422(95)00171-3
159048 - Glycosmis parviflora: 10.1016/0031-9422(95)00171-3
76967 - Glycosmis pentaphylla: 10.1021/NP0400611
159052 - Glycosmis trichanthera: 10.1016/S0031-9422(97)00986-2
1006069 - Haplophyllum bucharicum: 10.1007/BF02238348
452771 - Haplophyllum buxbaumii:
452773 - Haplophyllum dauricum: 10.1007/BF00574794
1006075 - Haplophyllum griffithianum:
1006077 - Haplophyllum myrtifolium: 10.1016/S0367-326X(03)00147-3
452779 - Haplophyllum obtusifolium:
266083 - Haplophyllum suaveolens: 10.1016/S0031-9422(00)85006-2
1006083 - Haplophyllum thesioides:
452784 - Haplophyllum tuberculatum:
2364054 - Helietta apiculata: 10.1055/S-2002-32898
1793828 - Leionema nudum: 10.1016/0040-4020(58)88046-1
1487144 - Myrtopsis myrtoidea: 10.1016/S0031-9422(00)86717-5
354507 - Orixa japonica: 10.1021/NP0401462
1136780 - Peltostigma guatemalense: 10.1080/14786410802228439
68554 - Phellodendron amurense: 10.1016/S0031-9422(97)01130-8
2492872 - Philotheca coccinea: 10.1016/0031-9422(91)83459-X
1279153 - Pitavia punctata: 10.1016/S0031-9422(00)97383-7
1654700 - Ravenia spectabilis: 10.1016/J.FITOTE.2004.03.008
452790 - Ruta chalepensis:
37565 - Ruta graveolens:
675743 - Ruta macrophylla: 10.1007/BF00055511
23513 - Rutaceae: 10.1021/NP50107A020
354517 - Skimmia reevesiana: 10.1016/S0031-9422(00)84814-1
2896588 - Spiranthera odoratissima:
354522 - Tetradium glabrifolium:
452797 - Thamnosma montana: 10.1016/S0040-4020(01)99086-6
159071 - Zanthoxylum ailanthoides:
2839963 - Zanthoxylum asiaticum:
354527 - Zanthoxylum avicennae:
2839964 - Zanthoxylum dimorphophyllum:
1056472 - Zanthoxylum mayu: 10.1055/S-2007-969890
354528 - Zanthoxylum nitidum:
2588167 - Zanthoxylum rubescens: 10.1055/S-2007-969634
354530 - Zanthoxylum schinifolium: 10.1055/S-2000-8648
328402 - Zanthoxylum simulans:
697043 - Zanthoxylum wutaiense: 10.1021/NP700719E
2099548 - Zanthoxylum zanthoxyloides:

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Yixuan Li, Weihua Zhang, Tingting Yin, Ce Wang, Feige Wang, Jing Sun, Lina Liu, Qinghuai Zhang, Chunze Zhang. Inhibition of UDP-glucuronosyltransferases by different furoquinoline alkaloids. Xenobiotica; the fate of foreign compounds in biological systems. 2020 Oct; 50(10):1170-1179. doi: 10.1080/00498254.2020.1760400. [PMID: 32367776]
Nishikant Wase, Boqiang Tu, James W Allen, Paul N Black, Concetta C DiRusso. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. Plant physiology. 2017 Aug; 174(4):2146-2165. doi: 10.1104/pp.17.00433. [PMID: 28652262]
Jih-Jung Chen, Ching-Yi Chung, Tsong-Long Hwang, Jinn-Fen Chen. Amides and benzenoids from Zanthoxylum ailanthoides with inhibitory activity on superoxide generation and elastase release by neutrophils. Journal of natural products. 2009 Jan; 72(1):107-11. doi: 10.1021/np800689b. [PMID: 19128011]
Luis Enrique Cuca Suarez, Manuel Elkin Pattarroyo, Jose Manuel Lozano, Franco Delle Monache. Biological activity of secondary metabolites from Peltostigma guatemalense. Natural product research. 2009; 23(4):370-4. doi: 10.1080/14786410802228439. [PMID: 19296377]
Hung-Yi Huang, Tsutomu Ishikawa, Chien-Fang Peng, Ian-Lih Tsai, Ih-Sheng Chen. Constituents of the root wood of Zanthoxylum wutaiense with antitubercular activity. Journal of natural products. 2008 Jul; 71(7):1146-51. doi: 10.1021/np700719e. [PMID: 18564877]
Jih-Jung Chen, Tzu-Ying Wang, Tsong-Long Hwang. Neolignans, a coumarinolignan, lignan derivatives, and a chromene: anti-inflammatory constituents from Zanthoxylum avicennae. Journal of natural products. 2008 Feb; 71(2):212-7. doi: 10.1021/np070594k. [PMID: 18211005]
Aleksandra Orlita, Matylda Sidwa-Gorycka, Jolanta Kumirska, Edmund Maliński, Ewa M Siedlecka, Jerzy Gajdus, Ewa Lojkowska, Piotr Stepnowski. Identification of Ruta graveolens L. metabolites accumulated in the presence of abiotic elicitors. Biotechnology progress. 2008 Jan; 24(1):128-33. doi: 10.1021/bp070261d. [PMID: 18052337]
Ipek Ostan, Hüsniye Saglam, M Emin Limoncu, Hatice Ertabaklar, Seray Ozensoy Toz, Yusuf Ozbel, Ahmet Ozbilgin. In vitro and in vivo activities of Haplophyllum myrtifolium against Leishmania tropica. The new microbiologica. 2007 Oct; 30(4):439-45. doi: . [PMID: 18080680]
Ming-Jen Cheng, Kuo-Hsiung Lee, Ian-Lih Tsai, Ih-Sheng Chen. Two new sesquiterpenoids and anti-HIV principles from the root bark of Zanthoxylum ailanthoides. Bioorganic & medicinal chemistry. 2005 Nov; 13(21):5915-20. doi: 10.1016/j.bmc.2005.07.050. [PMID: 16140017]
Chihiro Ito, Masataka Itoigawa, Atsuko Sato, Choudhury M Hasan, Mohammad A Rashid, Harukuni Tokuda, Teruo Mukainaka, Hoyoku Nishino, Hiroshi Furukawa. Chemical constituents of Glycosmis arborea: three new carbazole alkaloids and their biological activity. Journal of natural products. 2004 Sep; 67(9):1488-91. doi: 10.1021/np0400611. [PMID: 15387647]
O Schimmer, I Kühne. Mutagenic compounds in an extract from Rutae Herba (Ruta graveolens L.). II. UV-A mediated mutagenicity in the green alga Chlamydomonas reinhardtii by furoquinoline alkaloids and furocoumarins present in a commercial tincture from Rutae Herba. Mutation research. 1990 Jan; 243(1):57-62. doi: 10.1016/0165-7992(90)90123-2. [PMID: 2300085]
O Schimmer, U Leimeister. The SCE-inducing potency of the furoquinoline alkaloid, gamma-fagarine, and a gamma-fagarine-containing tincture from Rutae Herba, in cultured human lymphocytes. Mutagenesis. 1989 Nov; 4(6):467-70. doi: 10.1093/mutage/4.6.467. [PMID: 2695761]
M Mizuta, H Kanamori. Mutagenic activities of dictamnine and gamma-fagarine from dictamni radicis cortex (Rutaceae). Mutation research. 1985 Dec; 144(4):221-5. doi: 10.1016/0165-7992(85)90054-5. [PMID: 4069140]