NCIOpen2_001552 (BioDeep_00000229776)

 

Secondary id: BioDeep_00000017778, BioDeep_00000265435

PANOMIX_OTCML-2023


代谢物信息卡片


2-Hydroxy-4-methoxybenzoic acid, 99\\%

化学式: C8H8O4 (168.0423)
中文名称: 4-甲氧基水杨酸
谱图信息: 最多检出来源 Homo sapiens(otcml) 13.66%

分子结构信息

SMILES: COC1=CC(=C(C=C1)C(=O)O)O
InChI: InChI=1S/C8H8O4/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11)

描述信息

4-methoxysalicylic acid is a methoxybenzoic acid.
4-Methoxysalicylic acid is a natural product found in Haplophyllum thesioides, Calophyllum polyanthum, and other organisms with data available.
2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.
2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.

同义名列表

14 个代谢物同义名

2-Hydroxy-4-methoxybenzoic acid, 99\\%; Benzoic acid, 2-hydroxy-4-methoxy-; 2-hydroxy-4-methoxy-benzoic acid; 4-methoxy-2-hydroxobenzoic acid; 2-Hydroxy-4-methoxybenzoic acid; 2-Hydroxy-4-methoxybenzoicacid; MRIXVKKOHPQOFK-UHFFFAOYSA-N; 4-methoxy-salicylic acid; 4-methoxy salicylic acid; 4-Methoxysalicylic acid; 2-Hydroxy-p-anisic Acid; 4-Methoxysalicylic; NCIOpen2_001552; 2-Hydroxy-4-methoxybenzoic acid



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Md Iqbal Alam, Mohammed A Alam, Ozair Alam, Amit Nargotra, Subhash Chandra Taneja, Surrinder Koul. Molecular modeling and snake venom phospholipase A2 inhibition by phenolic compounds: Structure-activity relationship. European journal of medicinal chemistry. 2016 May; 114(?):209-19. doi: 10.1016/j.ejmech.2016.03.008. [PMID: 26986086]
  • Ramar Perumal Samy, Ponnampalam Gopalakrishnakone, Vincent Tk Chow. Therapeutic application of natural inhibitors against snake venom phospholipase A(2). Bioinformation. 2012; 8(1):48-57. doi: 10.6026/97320630008048. [PMID: 22359435]
  • Smitha Jayaram, Shylaja M Dharmesh. Assessment of antioxidant potentials of free and bound phenolics of Hemidesmus indicus (L) R.Br against oxidative damage. Pharmacognosy research. 2011 Oct; 3(4):225-31. doi: 10.4103/0974-8490.89741. [PMID: 22224044]
  • Carmela Fimognari, Monia Lenzi, Lorenzo Ferruzzi, Eleonora Turrini, Paolo Scartezzini, Ferruccio Poli, Roberto Gotti, Alessandra Guerrini, Giovanni Carulli, Virginia Ottaviano, Giorgio Cantelli-Forti, Patrizia Hrelia. Mitochondrial pathway mediates the antileukemic effects of Hemidesmus indicus, a promising botanical drug. PloS one. 2011; 6(6):e21544. doi: 10.1371/journal.pone.0021544. [PMID: 21738701]
  • M Gayathri, K Kannabiran. Effect of 2-Hydroxy-4-Methoxy Benzoic Acid from the Roots of Hemidesmus indicus on Streptozotocin-induced Diabetic Rats. Indian journal of pharmaceutical sciences. 2009 Sep; 71(5):581-5. doi: 10.4103/0250-474x.58180. [PMID: 20502585]
  • A Vidhya, M Indira. Protective effect of Quercetin in the Regression of Ethanol-Induced Hepatotoxicity. Indian journal of pharmaceutical sciences. 2009 Sep; 71(5):527-32. doi: 10.4103/0250-474x.58186. [PMID: 20502571]
  • Mahalingam Gayathri, Krishnan Kannabiran. Hypoglycemic activity of Hemidesmus indicus R. Br. on streptozotocin-induced diabetic rats. International journal of diabetes in developing countries. 2008 Jan; 28(1):6-10. doi: 10.4103/0973-3930.41979. [PMID: 19902032]
  • Nadana Saravanan, Namasivayam Nalini. Effect of 2-hydroxy 4-methoxy benzoic acid on an experimental model of hyperlipidaemia, induced by chronic ethanol treatment. The Journal of pharmacy and pharmacology. 2007 Nov; 59(11):1537-42. doi: 10.1211/jpp.59.11.0011. [PMID: 17976265]
  • Nadana Saravanan, Namasivayam Nalini. Inhibitory effect of Hemidesmus indicus and its active principle 2-hydroxy 4-methoxy benzoic acid on ethanol-induced liver injury. Fundamental & clinical pharmacology. 2007 Oct; 21(5):507-14. doi: 10.1111/j.1472-8206.2007.00500.x. [PMID: 17868203]
  • Lei Wang, Zhi-qi Yin, Lei-hong Zhang, Wen-cai Ye, Xiao-qi Zhang, Wen-bin Shen, Shou-xun Zhao. [Chemical constituents from root barks of Periploca sepium]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Jul; 32(13):1300-2. doi: . [PMID: 17879730]
  • Nadana Saravanan, Srinivasagam Rajasankar, Namasivayam Nalini. Antioxidant effect of 2-hydroxy-4-methoxy benzoic acid on ethanol-induced hepatotoxicity in rats. The Journal of pharmacy and pharmacology. 2007 Mar; 59(3):445-53. doi: 10.1211/jpp.59.3.0015. [PMID: 17331349]
  • Bethwell O Owuor, Daniel P Kisangau. Kenyan medicinal plants used as antivenin: a comparison of plant usage. Journal of ethnobiology and ethnomedicine. 2006 Feb; 2(?):7. doi: 10.1186/1746-4269-2-7. [PMID: 16451723]
  • H S Yun-Choi, J H Kim, J R Lee. Potential inhibitors of platelet aggregation from plant sources, III. Journal of natural products. 1987 Nov; 50(6):1059-64. doi: 10.1021/np50054a008. [PMID: 3127544]