Exact Mass: 276.13213
Exact Mass Matches: 276.13213
Found 500 metabolites which its exact mass value is equals to given mass value 276.13213,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Dihydromethysticin
Dihydromethysticin is found in beverages. Dihydromethysticin is isolated from Piper methysticum (kava). FDA advises against use of kava in food due to potential risk of severe liver damage (2002) Dihydromethysticin is one of the six major kavalactones found in the kava plant Dihydromethysticin is a member of 2-pyranones and an aromatic ether. Dihydromethysticin is a natural product found in Piper methysticum, Piper majusculum, and Aniba hostmanniana with data available. Dihydromethysticin is one of the six major kavalactones found in the kava plant; has marked activity on the induction of CYP3A23. Dihydromethysticin is one of the six major kavalactones found in the kava plant; has marked activity on the induction of CYP3A23.
Sudan_II
C.i. solvent orange 7 appears as red crystals. Insoluble in water. Sudan II is a member of azobenzenes.
Hamaudol
Hamaudol is a member of chromenes. Hamaudol is a natural product found in Saposhnikovia divaricata, Angelica japonica, and other organisms with data available. Hamaudol is a chromone isolated from Saposhnikovia divaricata. Hamaudol shows significant inhibitory activity on cyclooxygenase (COX)-1 and COX-2 activities with IC50 values of 0.30, 0.57 mM, respectively, and has potent analgesia and anti-inflammary effects[1][2]. Hamaudol is a chromone isolated from Saposhnikovia divaricata. Hamaudol shows significant inhibitory activity on cyclooxygenase (COX)-1 and COX-2 activities with IC50 values of 0.30, 0.57 mM, respectively, and has potent analgesia and anti-inflammary effects[1][2].
Saccharopine
Saccharopine is an intermediate in the degradation of lysine, formed by the condensation of lysine and alpha-ketoglutarate. The saccharopine pathway is the main route for lysine degradation in mammals, and its first two reactions are catalyzed by enzymatic activities known as lysine-oxoglutarate reductase (LOR) and saccharopine dehydrogenase (SDH), which reside on a single bifunctional polypeptide (LOR/SDH) (EC 1.5.1.8). The reactions involved with saccharopine dehydrogenases have very strict substrate specificity for L-lysine, 2-oxoglutarate, and NADPH. LOR/SDH has been detected in a number of mammalian tissues, mainly in the liver and kidney, contributing not only to the general nitrogen balance in the organism but also to the controlled conversion of lysine into ketone bodies. A tetrameric form has also been observed in human liver and placenta. LOR activity has also been detected in brain mitochondria during embryonic development, and this opens up the question of whether or not lysine degradation has any functional significance during brain development. As a result, there is now a new focus on the nutritional requirements for lysine in gestation and infancy. Finally, LOR and/or SDH deficiencies seem to be involved in a human autosomal genetic disorder known as familial hyperlysinemia, which is characterized by serious defects in the functioning of the nervous system and characterized by a deficiency in lysine-ketoglutarate reductase, saccharopine dehydrogenase, and saccharopine oxidoreductase activities. Saccharopinuria (high amounts of saccharopine in the urine) and saccharopinemia (an excess of saccharopine in the blood) are conditions present in some inherited disorders of lysine degradation (PMID: 463877, 10567240, 10772957, 4809305). If present in sufficiently high levels, saccharopine can act as an acidogen and a metabotoxin. An acidogen is an acidic compound that induces acidosis, which has multiple adverse effects on many organ systems. A metabotoxin is an endogenously produced metabolite that causes adverse health effects at chronically high levels. Saccharopine is an organic acid. Abnormally high levels of organic acids in the blood (organic acidemia), urine (organic aciduria), the brain, and other tissues lead to general metabolic acidosis. Acidosis typically occurs when arterial pH falls below 7.35. In infants with acidosis, the initial symptoms include poor feeding, vomiting, loss of appetite, weak muscle tone (hypotonia), and lack of energy (lethargy). Many affected children with organic acidemias experience intellectual disability or delayed development. Amino acid from Saccharomyces cerevisiae and Neurospora crassaand is also found in mushrooms and seeds
4-Hydroxycinnamoylagmatine
4-Hydroxycinnamoylagmatine is found in cereals and cereal products. 4-Hydroxycinnamoylagmatine is isolated from barley seedlings. Isolated from barley seedlings. 4-Hydroxycinnamoylagmatine is found in cereals and cereal products.
Lactucin
Lactucin is found in chicory. Lactucin is a constituent of Cichorium intybus (chicory) Lactucin is a bitter substance that forms a white crystalline solid and belongs to the group of sesquiterpene lactones. It is found in some varieties of lettuce and is an ingredient of lactucarium. It has been shown to have analgesic and sedative properties Constituent of Cichorium intybus (chicory)
5-Amino-6-ribitylamino uracil
C9H16N4O6 (276.10697960000005)
5-Amino-6-ribitylamino uracil is an intermediate in riboflavin metabolism. It is converted from 5-amino-6-(5-phosphoribitylamino)uracil via dephosphorylation by the enzyme phosphohistidine phosphatase 1 (EC 3.1.3.-). It is considered to be the second product of the riboflavin synthase reaction (PMID: 14245407). Humans do not have all the enzymes needed to synthesize or metabolize riboflavin. However, gut microflora do have the necessary enzymatic machinery to produce and metabolize this vitamin. Riboflavin (or vitamin B2) is an easily absorbed micronutrient with a key role in maintaining health in humans and animals. It is the central component of the cofactors FAD and FMN, and is therefore required by all flavoproteins. Riboflavin is yellow or yellow-orange in colour and in addition to being used as a food colouring it is also used to fortify some foods including baby foods, breakfast cereals, pastas, sauces, processed cheese, fruit drinks, vitamin-enriched milk products, some energy drinks, and vitamin supplements. 5-amino-6-(d-ribitylamino)uracil, also known as 5-amino-6-ribitylamino-2,4-(1h,3h)pyrimidinedione or 5-arpd, is a member of the class of compounds known as pentoses. Pentoses are monosaccharides in which the carbohydrate moiety contains five carbon atoms. 5-amino-6-(d-ribitylamino)uracil is soluble (in water) and a very weakly acidic compound (based on its pKa). 5-amino-6-(d-ribitylamino)uracil can be found in a number of food items such as radish (variety), chinese cabbage, common beet, and spinach, which makes 5-amino-6-(d-ribitylamino)uracil a potential biomarker for the consumption of these food products. 5-amino-6-(d-ribitylamino)uracil exists in E.coli (prokaryote) and yeast (eukaryote).
Pentalenolactone
A sesquiterpene lactone that is isolated from several Streptomyces species and exhibits antibiotic activity.
Triethyl citrate
Triethyl citrate is used in foods as a flavouring agent, solvent and surface-active agent Triethyl citrate is an ester of citric acid. It is a colorless, odorless liquid used as a food additive (E number E1505) to stabilize foams, especially as whipping aid for egg white. In pharmaceutical coatings and plastics It is used in foods as a flavouring agent, solvent and surface-active agent
10-Acetoxytoxol
10-Acetoxytoxol is found in herbs and spices. 10-Acetoxytoxol is a constituent of Helichrysum italicum (curry plant)
Acetylpterosin C
Acetylpterosin C is found in green vegetables. Acetylpterosin C is from Pteridium aquilinum (bracken fern
Ascochitine
Causes brown rot in broad bean
6-[3-(2-hydroxypropan-2-yl)oxiran-2-yl]-7-methoxy-2H-chromen-2-one
3-(7-methoxy-2-oxo-2H-chromen-8-yl)-2,2-dimethylpropanoic acid
Mebhydrolin
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist Mebhydrolin is a first-generation antihistamine. Mebhydrolin is a specific histamine H1 receptor antagonist.
1-[(2,5-Dimethylphenyl)azo]-2-naphthalenol
1-[(2,5-Dimethylphenyl)azo]-2-naphthalenol is a food dye; delisted for foods by FDA. Food dye; delisted for foods by FDA
5-De-O-methyltoddanol
5-De-O-methyltoddanol is found in citrus. 5-De-O-methyltoddanol is a constituent of the stem bark of Citrus grandis (pummelo). Constituent of the stem bark of Citrus grandis (pummelo). 5-De-O-methyltoddanol is found in citrus.
N-lactoyl-Tryptophan
N-lactoyl-Tryptophan is lactoyl derivative of tryptophan. N-lactoyl-amino acids are ubiquitous pseudodipeptides of lactic acid and amino acids that are rapidly formed by reverse proteolysis. A protease, cytosolic nonspecific dipeptidase 2 (CNDP2), catalyzes their formation. The plasma levels of these metabolites strongly correlate with plasma levels of lactate and amino acid. (PMID: 25964343)
5-Benzylacyclouridine
D004791 - Enzyme Inhibitors
9-Methoxyellipticine
D000970 - Antineoplastic Agents > D000972 - Antineoplastic Agents, Phytogenic > D004611 - Ellipticines
2-[[2-[(Dimethylamino)methyl]phenyl]thio]-5-fluoroaniline
C15H17FN2S (276.10964140000004)
Creatine glutamate
C9H16N4O6 (276.10697960000005)
Etintidine
N-(4-Aminobutyl)-N-ethylisoluminol
2-(7'-methylthio)heptylmalate
C12H20O5S (276.10313900000006)
2-(7-methylthio)heptylmalate is practically insoluble (in water) and a weakly acidic compound (based on its pKa). 2-(7-methylthio)heptylmalate can be found in a number of food items such as lima bean, redcurrant, butternut, and green zucchini, which makes 2-(7-methylthio)heptylmalate a potential biomarker for the consumption of these food products.
3-(7'-methylthio)heptylmalate
C12H20O5S (276.10313900000006)
3-(7-methylthio)heptylmalate is practically insoluble (in water) and a weakly acidic compound (based on its pKa). 3-(7-methylthio)heptylmalate can be found in a number of food items such as teff, babassu palm, corn, and cauliflower, which makes 3-(7-methylthio)heptylmalate a potential biomarker for the consumption of these food products.
7-(3,3-Dimethylallyloxy)-6-hydroxy-5-methoxycoumarin
6,7,9alpha-Trihydroxy-3,8,11alpha-trimethylcyclohexo[d,e]-coumarin
Cyclo(Tyr-Leu)
Cyclo(Tyr-Leu) is a natural product found in Nocardia alba and Portulaca oleracea with data available. Cyclo(Tyr-Leu) is a cyclic dipeptide[1]. Cyclo(Tyr-Leu) is a cyclic dipeptide[1]. Cyclo(Tyr-Leu) is a cyclic dipeptide[1].
URSINOIC ACID
Origin: Plant; SubCategory_DNP: Triterpenoids
6-(2,3-epoxy-1-hydroxy-3methylbut)-7-methoxycoumarin|6-[(3,3-dimethyl-oxiranyl)-hydroxy-methyl]-7-methoxy-chromen-2-one|Lophopterol
1-(5,7-dihydroxy-2,2,6-trimethyl-2 h -1-benzopyran-8-yl)-2-methyl-1-propanone
(4S,4aR,6R)-1-acetyl-6-(acetyloxy)-4,4a,5,6-tetrahydro-4,7-dimethylnaphthalen-2(3H)-one|eupatorone
Ac-1beta-1-Hydroxy-13-nor-6,9-eremophiladiene-8,11-dione
8-(1,2-epoxy-3-hydroxy-3-methylbutyl)-7-methoxycoumarin
3-(3-Methyl-2-butenyl)-4-isobutyryloxybenzoic acid
8-hydroxy-3,7-dimethoxy-1,2,3,11a-tetrahydro-benzo[e]pyrrolo[1,2-a][1,4]diazepine-5-one|Methyl-Neotramizin A|Methyl-Neotramizin B
(2E,2E)-4-Me ether,Me ester-3-[4-Hydroxy-3-(4-hydroxy-3-methyl-2-buteny)phenyl]-2-propenoic acid|methyl 3-(4-hydroxyprenyl)-coumarate 4-O-methyl ether
8,12-epoxy-1alpha-methoxy-4alphaH,5alphaH-eudesma-7,11-dien-6,9-dione
6,8-Dimethoxy-3-isobutyl-2-methyl-4H-1-benzopyran-4-one
2,3-Dihydro-5,7-dihydroxy-2,6-dimethyl-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
8beta-hydroxyeremophil-3,7(11)-diene-8alpha,12(6alpha,15)-diolide
(S)-Aspertetronin A|2-[(1E,3E)-hexa-1,3-dien-1-yl]-5-methoxy-2-methyl-4-[(2E)-1-oxobut-2-en-1-yl]furan-3-(2H)-one|aspertetronin A
3beta-acetoxy-6-acetyl-2alpha-isopropenyl-5-hydroxy-2,3H-benzofuran
9-Methoxyellipticine
D000970 - Antineoplastic Agents > D000972 - Antineoplastic Agents, Phytogenic > D004611 - Ellipticines
2-Methyl-2-isobutyryl-6,7-dimethoxy-2H-1-benzopyran
methyl (4R,5S,6R,7R,11S)-2,9-dioxo-1(10)-aromadendren-12-oate
(R)-(+)-7-methoxy-8-(2,3-epoxy-3-methylbutoxy)-coumarin
6,8-dihydroxy-7-acetyl-1-keto-3-methoxy-4,4-dimethyl-1,4-dihydronaphthalene
2-(4-Hydroxyphenethyl)-4-hydroxy-6-oxo-1-cyclohexene-1-carboxylic acid
2-(1-Hydroxy-1-methylethyl)-4-methoxy-2,3-dihydro-7H-furo[3,2-g][1]benzopyran-7-one
4,7-Benzofurandione, 3-(hydroxymethyl)-6-methoxy-5-(3-methyl-2-butenyl)-
(+)-(S)-8,9-dihydro-9-phenyl-7H-phenalene-1,2-diol|monolaterol
2,3-Dihydro-5,7-dihydroxy-2,8-dimethyl-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
Chlorajapolide F
3beta-acetoxy-6,9-dien-8-oxoeremophil-12-nor-11-one
1-(3,4-Dihydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)-propan|1-(3,4-dihydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)propane
8-(2,3-epoxy-1-hydroxy-3-methylbutyl)-7-methoxycoumarin
7-Hydroxy-5-(4-hydroxy-2-oxopentyl)-2-methylchromone
2,2-dimethyl-6-hydroxy-8-(3-hydroxy-3-methyl-1E-butenyl)-chromanone
(6??,8??OH)-6,8-Dihydroxy-3-oxo-1,7(11),9-eremophilatrien-12,8-olide
(R)-4-(1-hydroxy-3-methylbutyl)-6H-[1,3]dioxolo[4,5-g]chromen-6-one|antidesnol
4-hydroxy-2-(3-hydroxy-2-methoxy-3-methyl-butylidene)-3,4-dihydro-2h-naphthalen-1-one
norpinguisone acetate
A natural product found in Porella chilensis and Porella recurva.
4-Methoxy-5-methyl-6-(3-methyl-2-butenyloxy)isobenzofuran-1,3-dione
(9betaH)-1alpha,4alpha-dihydroxy-10-oxo-1,10-seco-1(10->9)abeoguaia-2,5,7(11)-trien-12,8beta-olide|millifolide C
(2S,3S,4R,5R)-2,5-epoxy-3,4-dimethyl-8,9-methylenedioxy-10-methoxy-6,11-benzocycloheptan-1-one|gymnothedelignan A
(3aR,4S,5aR,10aR,10bR)-3,3a,4,5,5a,9,10,10b-octahydro-3a,4,10b-trimethyl-2H,7H-naphtho[4a,4-b:1,8-b?c?]difuran-2,7-dione|ciliatolide A
3-crotonoyl-5-<(1E,3E)-hexa-1,3-dienyl>-4-methoxy-5-methylfuran-2(5H)-one|iso-aspertetronin A
2-methyl-6-hydroxycyclohexenyl-3-methyl-1-acetophenone ether
3-oxo-8alpha-methoxy-10aH-eremophila-1,7(11)-dien-12,8beta-olide|3-oxo-8alpha-methoxy-10alphaH-eremophila-1,7(11)-dien-12,8beta-olide|8beta-hydroxy-8alpha-methoxy-3-oxo-eremophil-1,7(11)-dien-12-oic acid lactone
13,14,15,16-tetranorlabd-7-en-(19,6beta),(12,17)-diolide|13,14,15,16-tetranorlabd-7-en-16,6beta:12,17-diolide|13,14,15,16-tetranorlabd-7-ene-19,6b:12,17-diolide
2-isopropyl-9S-methoxy-7R-methyl-6,7-dihydro-2H-furo[3,2-h]isochromen-3(9H)-one|ustusorane D
6-Deoxy-2-O-methyl-3-C-methuyltalose, 9CI-1,4-Di-Ac
2,3-Dihydro-6,7-dimethoxy-2-methyl-2-(2-methyl-1-propenyl)-4H-1-benzopyran-4-one
1,6-dichloro-1,6-dimethyl-4-(propan-2-yl)decahydronaphthalene
2-hexyl-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one|5-hydroxy-2-hexyl-7-methoxy-4-chromone
2,2-Dimethyl-5-methoxy-2H-1-benzopyran-6-propionic acid methyl ester
methyl-3-<3,3-dimethyl-3-hydroxyallyl>-p-coumarate-O-methyl ether
3-carboxy-10-(methylsulfanyl)-2-oxodecanoate
C12H20O5S (276.10313900000006)
Triethylcitrate
CONFIDENCE standard compound; INTERNAL_ID 2857 CONFIDENCE standard compound; INTERNAL_ID 8781
ascr#1
An (omega-1)-hydroxy fatty acid ascaroside obtained by formal condensation of the alcoholic hydroxy group of (6R)-6-hydroxyheptanoic acid with ascarylopyranose (the alpha anomer). It is a major component of the dauer pheromone, used by the nematode Caenorhabditis elegans as a population-density signal to promote entry into an alternate larval stage, the nonfeeding and highly persistent dauer diapause. It has also been found in Pristionchus pacificus and the sour paste nematode Panagrellus redivivus. CONFIDENCE standard compound; INTERNAL_ID 97
Gly Gly Gly Ser
C9H16N4O6 (276.10697960000005)
Gly Gly Ser Gly
C9H16N4O6 (276.10697960000005)
Gly Ser Gly Gly
C9H16N4O6 (276.10697960000005)
Ser Gly Gly Gly
C9H16N4O6 (276.10697960000005)
Mebhydrolin
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist Mebhydrolin is a specific histamine H1 receptor antagonist.
SC-66
SC66 is an Akt inhibitor, reduces cell viability in a dose- and time-dependent manner, inhibits colony formation and induces apoptosis in hepatocellular carcinoma (HCC) cells.
oscr#1
An omega-hydroxy fatty acid ascaroside obtained by formal condensation of the alcoholic hydroxy group of 7-hydroxyheptanoic acid with ascarylopyranose (the alpha anomer). It is a metabolite of the nematode Caenorhabditis elegans.
3-(2-TriMethylsilanyl-ethoxyMethyl)-6-vinyl-3H-[1,2,3]triazolo[4,5-b]pyridine
(1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid
C15H20O3Si (276.11816500000003)
Taglutimide
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
1,2,3,6,7,8,11,12-OCTAHYDROBENZO[E]PYREN-9(10H)-ONE
Oxagrelate
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor
dimethyl 1-allyl-5,5-difluorocyclohexane-1,3-dicarboxylate
tert-butyl 2-(3-amino-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl)acetate
1-(tert-Butoxycarbonyl)-5-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid
2-(4-(PIPERAZIN-1-YL)PHENYL)PYRIMIDINE HYDROCHLORIDE
Urea, N-(3-fluorophenyl)-N-[3-(2-furanyl)-1-methylpropyl]- (9CI)
methyl 3-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
METHYL 2-((4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)METHYL)BENZOATE
1-TERT-BUTYL 5-METHYL 1H-INDAZOLE-1,5-DICARBOXYLATE
[(2S)-1-(4-nitrophenyl)pyrrolidin-2-yl]methyl prop-2-enoate
1-Benzyl-3-methylpiperidin-4-ylamine dihydrochloride
Methyl 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
(4-Methoxycarbonylmethyl)phenylboronic acid pinacol ester
methyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
4-(METHOXYCARBONYL)-2-METHYLPHENYLBORONIC ACID PINACOL ESTER
METHYL 2-(3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)ACETATE
METHYL 2-(2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)ACETATE
3-(1,3-Dioxolan-2-yl)phenylboronic acid pinacol ester
1,2:3,4-Di-O-isopropylidene-6-thio-a-D-galactopyranose
C12H20O5S (276.10313900000006)
3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoic acid
1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole
C11H16BF3N2O2 (276.12568619999996)
6-t-butyl-4-piperazinothieno[3,2-d]pyrimidine
C14H20N4S (276.14086000000003)
Benzoic acid, 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, Methyl ester
5-ethyl-1-(methoxymethyl)-5-phenyl-1,3-diazinane-2,4,6-trione
methyl 2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
5-methyl-5-[4-(3-methylbutoxy)phenyl]imidazolidine-2,4-dione
4-(1-ADAMANTYL)-6-(METHYLTHIO)-1,3,5-TRAZIN-2-AMINE
C14H20N4S (276.14086000000003)
(R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
ETHYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE
4-(Acetoxymethyl)benzeneboronic acid pinacol ester
4-(METHYLAMINO)-1-BENZYLPIPERIDINE DIHYDROCHLORIDE
ETHYL 4-(2-HYDROXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE
1-Butyl-3-methylimidazolium Trifluoro(trifluoromethyl)borate
Ethyl 4-hydroxy-2-oxo-1-propyl-1,2-dihydro-1,8-naphthyridine-3-carboxylate
3,5-di(pyridin-2-yl)phenylboronic acid
C16H13BN2O2 (276.10700280000003)
5-[(2-methylpropan-2-yl)oxycarbonylamino]-1H-indole-2-carboxylic acid
3-(2,5-dimethylphenyl)-1-phenylpyrazole-4-carbaldehyde
1-(tert-butyl-dimethyl-silanyl)-1h-pyrrolo[2,3-b]pyridin-5-yl boronic acid
1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 1-[(1,1-dimethylethyl)dimethylsilyl]-
C14H20N2O2Si (276.12939800000004)
2-([1,1-BIPHENYL]-4-CARBONYL)-3-(DIMETHYLAMINO)ACRYLONITRILE
(R)-1-Benzyl-3-dimethylaminopyrrolidine Dihydrochloride
1,8-Diazaspiro[4.5]decane-1-carboxylic acid, 1,1-dimethylethyl ester, (Hydrochloride) (1:1)
6-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
4,4,5,5-TETRAMETHYL-2-(4-(TRIFLUOROMETHYL)CYCLOHEX-1-EN-1-YL)-1,3,2-DIOXABOROLANE
Ethambutol hydrochloride
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D000995 - Antitubercular Agents C254 - Anti-Infective Agent > C52588 - Antibacterial Agent > C280 - Antitubercular Agent Ethambutol dihydrochloride (Emb dihydrochloride) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases. Target: Antibacterial Ethambutol dihydrochloride (Emb dihydrochloride) directly affects two polymers, arabinogalactan (AG) and lipoarabinomannan (LAM) in Mycobacterium smegmatis. In M. smegmatis, Ethambutol inhibits synthesis of arabinan completely and inhibits AG synthesis most likely as a consequence of this; more than 50\% of the cell arabinan is released from the bacteria following Ethambutol treatment, whereas no galactan is released. Ethambutol main targets against embB gene product in M. avium. Ethambutol induces 60\% changes in the embB gene in M. tuberculosis resistant mutants [1]. Ethambutol dihydrochloride (Emb dihydrochloride) is effective against actively growing microorganisms of the genus Mycobacterium, including M. tuberculosis. Nearly all strains of M. tuberculosis and M. kansasii as well as a number of strains of the M. aviumcomplex (MAC) are sensitive to Ethambutol. [1] Ethambutol dihydrochloride (Emb dihydrochloride) is potency against M. tuberculosis (H37Rv) with MIC of 0.5 μg/mL in vitro [2]. Ethambutol is efficient on treatment of mycobacterial-infected macrophages. When M. tuberculosis infected macrophages are treated with 6 μg/mL Ethambutol, the log CFUs following treatment for 3 days is 4.17, while value in control group is 4.8. The MICs for M. avium (MTCC 1723) and M. smegmatis (MTCC 6) are 15 μg/mL and 0.18 μg/mL, respectively. Ethambutol is efficient in animal model. 100 mg/kg Ethambutol given orally 15 days post i.v. infection 1 ×/week for 5 weeks, induces a lower log CFU compared with untreatment (4.59 vs 5.07) [3].
4,4,5,5-TETRAMETHYL-2-(4-(OXIRAN-2-YLMETHOXY)PHENYL)-1,3,2-DIOXABOROLANE
methyl 2-tert-butyl-5-nitro-1H-indole-7-carboxylate
(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
2-acetamido-3-(6-Methoxy-1H-indol-3-yl)propanoic acid
4-(1-PIPERIDINYLMETHYL)-BENZENEMETHANAMINEDIHYDROCHLORIDE
(3R)-1-benzyl-N,N-dimethylpyrrolidin-3-amine,dihydrochloride
Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
ethyl 5-<2-(dimethylamino)ethoxy>-1H-indole-2-carboxylate
1,2-o-isopropylidene-3-benzyloxy-5,6-dideoxy-glucofuranose
Ethyl 1-(4-methoxybutyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate
ETHYL 7-ACETAMIDO-4,5-DIHYDRO-1H-BENZO[D]AZEPINE-3(2H)-CARBOXYLATE
5-tert-butyl-2-[(4-fluorophenyl)methyl]pyrazole-3-carboxylic acid
Tert-butyl 2-(2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)acetate
2-Morpholino-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethanamine
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzothiazol-2-amine
1-(4-isopropylphenyl)-5-phenylpenta-1,4-dien-3-one
TERT-BUTYL ((2-(TRIFLUOROMETHYL)PYRIDIN-4-YL)METHYL)CARBAMATE
Methyl 4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
Y-26763
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
6-fluoro-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
N-(4-TERT-BUTYL-PHENYL)-6-CHLORO-PYRIMIDINE-2,4-DIAMINE
Tris(isopropenyloxy)(phenyl)silane
C15H20O3Si (276.11816500000003)
TERT-BUTYL ((6-(TRIFLUOROMETHYL)PYRIDIN-2-YL)METHYL)CARBAMATE
2-[4-[(E)-N-hydroxy-C-methylcarbonimidoyl]phenoxy]-1-piperidin-1-ylethanone
4-(4-CHLOROBENZYL)-3-METHYL-5-((R)-PYRROLIDIN-2-YL)-4H-1,2,4-TRIAZOLE
N-[3-Cyano-3-[4-(dicyanomethyl)phenyl]-2-propenylidene]-N-ethyl-ethaniminium inner salt
(3S,5R)-tert-Butyl4-(chlorocarbonyl)-3,5-dimethylpiperazine-1-carboxylate
Pyrido[2,1-f]purine-2,4,6(1H,3H,7H)-trione,8,9-dihydro-1,3,8,8-tetramethyl-
C13H16N4O3 (276.12223459999996)
(3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester
tert-butyl 2,8-diazaspiro[4.5]decane-2-carboxylatehydrochloride
tert-Butyl 2,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride
Methyl 5-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
tert-Butyl 2,6-diazaspiro[4.5]decane-6-carboxylate hydrochloride
5-(2-adamantylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBONYL CHLORIDE
trimethyl-(2-trimethylsilyl-1-trimethylsilyloxyethenoxy)silane
etintidine
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent > C29702 - Histamine-2 Receptor Antagonist D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists
TERT-BUTYL 6-AMINO-3,3-DIMETHYL-2-OXOINDOLINE-1-CARBOXYLATE
1,3-diisocyanato-2-methyl-benzene, 2-methyloxirane, oxirane
5-(3-(1-Methylcyclopropyl)propyl)-1H-pyrano(2,3-d)pyrimidine-2,4,7(3H)-trione
N-[(1s)-1-(Aminocarbonyl)-4-(Ethanimidoylamino)butyl]benzamide
(S)-2-((S)-2-Hydroxypropanamido)-3-(1H-indol-3-yl)propanoic acid
7-[(3,6-dideoxy-alpha-L-arabino-hexopyranosyl)oxy]heptanoic acid
Butanedioic acid, methyl-, bis(trimethylsilyl) ester
(5R,6R,7S,8S)-5-(Hydroxymethyl)-2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-A]pyridine-6,7,8-triol
2,4-Dihydroxy-N-[2-(2-mercapto-vinylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide
2-(7-Methylsulfanylheptyl)-3-oxobutanedioic acid
C12H20O5S (276.10313900000006)
4-methyl-4-sulfanylpentan-2-one-[CysGly] conjugate
2-[[(2R)-2-amino-3-(2-methyl-4-oxopentan-2-yl)sulfanylpropanoyl]amino]acetic acid
4-Amino-5-[2-[carbamimidoyl(methyl)amino]acetyl]peroxy-5-oxopentanoic acid
C9H16N4O6 (276.10697960000005)
4-Amino-5-(2-amino-3-methylpentanoyl)peroxy-5-oxopentanoic acid
3-Carboxylato-2-(4-carboxybutyryloxy)-N,N,N-trimethyl-1-propaneaminium
[3-Carboxy-2-(2-carboxybutanoyloxy)propyl]-trimethylazanium
(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoic acid
A diester resulting from the formal sequential esterification of the hydroxy group of one molecule of (3R)-3-hydroxybutyric acid with the carboxy group of a second, followed by the esterification of the hydroxy group of the product with the carboxy group of a third molecule of (3R)-3-hydroxybutyric acid. Isolated from the Japanese inedible mushroom Hypoxylon truncatum and also the sponge-derived actinomycete Micromonospora sp. RV43.
4-[[(Cyclohexylamino)-oxomethyl]amino]benzoic acid methyl ester
1-Cyclohexyl-3-(2,3-dihydro-1,4-benzodioxin-6-yl)urea
N-(4-methylphenyl)-4-tetrazolo[1,5-a]quinoxalinamine
1-[4-[(2-Methyl-4-quinolinyl)amino]phenyl]ethanone
5-methyl-3-(2-morpholino-2-oxoethyl)-1,3-benzoxazol-2(3H)-one
5-[(2,4-Diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenol
C13H16N4O3 (276.12223459999996)
N-(2-methoxyethyl)-5-(3-methoxyphenyl)-1,2-oxazole-3-carboxamide
N-(3-methylphenyl)-4-tetrazolo[1,5-a]quinoxalinamine
(1-Methylsulfonyl-4-piperidinyl)-(4-morpholinyl)methanone
N-cyclohexyl-N,4-dimethyl-5-thieno[3,2-b]pyrrolecarboxamide
5-Amino-1-ethyl-3-(1-naphthalenylmethyl)-4-pyrazolecarbonitrile
6-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3-oxohexanoic acid
(5R)-5-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3-oxohexanoic acid
7-[(2E)-2-[(2-methylphenyl)methylidene]hydrazinyl]-7-oxoheptanoic acid
1-[(1R,2aS,8bS)-1-(hydroxymethyl)-4-methyl-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-2-yl]-2-methoxyethanone
1-[(1S,2aS,8bS)-1-(hydroxymethyl)-4-methyl-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-2-yl]-2-methoxyethanone
1-[(1R,2aR,8bR)-1-(hydroxymethyl)-4-methyl-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-2-yl]-2-methoxyethanone
[(2S)-3-carboxy-2-(4-carboxybutanoyloxy)propyl]-trimethylazanium
[(2R)-3-carboxy-2-(4-carboxybutanoyloxy)propyl]-methyl-bis(trideuteriomethyl)azanium
Ethyl 1,2,7-trimethyl-4-nitro-1H-indole-3-carboxylate
alpha-Cyclopentylphenylacetic acid trimethylsilyl ester
3-Benzyl-6-methyl-1,2,3,4-tetrahydro-gamma-carboline
3,3-Dimethyl-1-phenyl-1,2,3,4-tetrahydro-gamma-carboline
5-Amino-6-(D-ribitylamino)uracil
C9H16N4O6 (276.10697960000005)
An aminouracil that is D-ribitol in which the hydroxy group at position 1 is substituted by the 6-amino group of 5,6-diaminouracil. Early intermediate in bacterial riboflavin synthesis.
2-[[2-[(Dimethylamino)methyl]phenyl]thio]-5-fluoroaniline
C15H17FN2S (276.10964140000004)
7-[2-[(2-methylphenyl)methylidene]hydrazinyl]-7-oxoheptanoic acid
carboxylato-PTIO
A benzoate that is the conjugate base of carboxy-PTIO, obtained by deprotonation of the carboxy group.
6-hydroxy-8-[(1e)-3-hydroxy-3-methylbut-1-en-1-yl]-2,2-dimethyl-3h-1-benzopyran-4-one
(4as,8s,10s,10as,10br)-10-hydroxy-8-(hydroxymethyl)-4a,10b-dimethyl-8h,9h,10h,10ah-cyclohexa[f]chromen-1-one
(2r)-1-[(2s)-4,6-dihydroxy-2-(prop-1-en-2-yl)-2,3-dihydro-1-benzofuran-5-yl]-2-methylbutan-1-one
(3s,6s)-3-[(2s)-butan-2-yl]-6-[(4-hydroxyphenyl)methyl]-3,6-dihydropyrazine-2,5-diol
(1r,11r,12e,17s)-12-ethylidene-10-methylidene-8,14-diazapentacyclo[9.5.2.0¹,⁹.0²,⁷.0¹⁴,¹⁷]octadeca-2,4,6,8-tetraene
(3s,6s)-3-[(4-hydroxyphenyl)methyl]-6-(2-methylpropyl)-3,6-dihydropyrazine-2,5-diol
(2s)-4-[(2e)-but-2-enoyl]-2-[(1e,3e)-hexa-1,3-dien-1-yl]-5-methoxy-2-methylfuran-3-one
5-hydroxy-7,7,9,9-tetramethyl-1h,2h,3h,10bh-pyrrolo[1,2-c]quinazoline-8,10-dione
(1r,6s,11as,14ar)-1-hydroxy-6-methyl-1h,6h,7h,11ah,12h,14h,14ah-cyclopenta[f]oxacyclotridecane-4,13-dione
(1r,11s,16s,18e)-18-ethylidene-2-methylidene-4,14-diazapentacyclo[12.3.1.0³,¹¹.0⁵,¹⁰.0¹¹,¹⁶]octadeca-3,5,7,9-tetraene
4-[(2e)-but-2-enoyl]-2-[(1e,3e)-hexa-1,3-dien-1-yl]-5-methoxy-2-methylfuran-3-one
5-[(5-amino-2,6-dihydroxypyrimidin-4-yl)amino]pentane-1,2,3,4-tetrol
C9H16N4O6 (276.10697960000005)