etintidine (BioDeep_00000831220)
代谢物信息卡片
化学式: C12H16N6S (276.1157096)
中文名称: 依汀替丁
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(N=CN1)CSCCN=C(NCC#C)NC#N
InChI: InChI=1S/C12H16N6S/c1-3-4-14-12(16-8-13)15-5-6-19-7-11-10(2)17-9-18-11/h1,9H,4-7H2,2H3,(H,17,18)(H2,14,15,16)
描述信息
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent > C29702 - Histamine-2 Receptor Antagonist
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists
同义名列表
1 个代谢物同义名
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- F A Wong, J R Lloyd, D W Graden. The metabolism of etintidine in rat, dog, and human.
Drug metabolism and disposition: the biological fate of chemicals.
1990 Nov; 18(6):949-53. doi:
NULL. [PMID: 1981542] - S M Huang, T B Marriott, H S Weintraub, J D Arnold, J Boccagno, R Abels, W Harris. Clinical pharmacokinetics of etintidine.
Biopharmaceutics & drug disposition.
1988 Sep; 9(5):477-86. doi:
10.1002/bod.2510090506. [PMID: 2906255] - S M Huang, T B Marriott, H S Weintraub, J A Boccagno, R Abels. The effect of food or milk on the bioavailability of etintidine in healthy subjects.
International journal of clinical pharmacology, therapy, and toxicology.
1988 Mar; 26(3):113-7. doi:
NULL. [PMID: 2900817] - S M Huang, L S Abrams, T B Marriott, H S Weintraub. Pharmacokinetics and bioavailability of etintidine in beagle dogs: effects of routes of administration, doses, dosage forms, and chronic dosing.
Biopharmaceutics & drug disposition.
1988 Jan; 9(1):71-83. doi:
10.1002/bod.2510090108. [PMID: 3342286] - S M Huang, T B Marriott, H S Weintraub, J D Arnold, J Boccagno, R Abels, W Harris. Single-dose and multiple-dose pharmacokinetics of etintidine in healthy volunteers.
European journal of clinical pharmacology.
1988; 34(1):101-4. doi:
10.1007/bf01061428. [PMID: 2896125] - S M Huang, H S Weintraub, T B Marriott, B Marinan, R Abels. Etintidine-propranolol interaction study in humans.
Journal of pharmacokinetics and biopharmaceutics.
1987 Dec; 15(6):557-68. doi:
10.1007/bf01068412. [PMID: 2897462] - S M Huang, H S Weintraub, T B Marriott, B Marinan, R Abels, P T Leese. Etintidine-theophylline interaction study in humans.
Biopharmaceutics & drug disposition.
1987 Nov; 8(6):561-9. doi:
10.1002/bdd.2510080607. [PMID: 2892545] - S M Huang, E Rubin, T B Marriott. A high-performance liquid chromatographic microassay employing a liquid-solid extraction technique for etintidine in plasma.
Pharmaceutical research.
1987 Apr; 4(2):133-6. doi:
10.1023/a:1016419019715. [PMID: 3509136] - C K Scott, L B Katz, D A Shriver. Pharmacological profile of etintidine, a new histamine H2-receptor antagonist.
Archives internationales de pharmacodynamie et de therapie.
1986 May; 281(1):5-21. doi:
NULL. [PMID: 2875695] - S Nishihara, A Tanaka, A Tazoe, K Yoshida, T Misawa, H Ibayashi. Inhibitory effect of etintidine (BL-5641), a new type of H2 receptor antagonist, on binding of [3H]-cimetidine to plasma membrane and histamine-stimulated cellular cAMP production in isolated guinea pig gastric glands.
Gastroenterologia Japonica.
1986 Apr; 21(2):106-11. doi:
10.1007/bf02774827. [PMID: 2872137] - D C Brater, W M Meyers, K A Dandekar, K A Pittman, W Peterson. Clinical pharmacology of etintidine in patients with duodenal ulcer.
European journal of clinical pharmacology.
1982; 23(6):495-500. doi:
10.1007/bf00637495. [PMID: 6130952]