9-Methoxyellipticine (BioDeep_00000312655)

natural product

代谢物信息卡片

9-Methoxyellipticine

化学式: C18H16N2O (276.1262566)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c12c(c3c([nH]1)ccc(c3)OC)c(c1c(c2C)ccnc1)C
InChI: InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3

描述信息

D000970 - Antineoplastic Agents > D000972 - Antineoplastic Agents, Phytogenic > D004611 - Ellipticines

同义名列表

1 个代谢物同义名

9-Methoxyellipticine

数据库引用编号

6 个数据库交叉引用编号

PubChem: 72512
ChEMBL: CHEMBL19954
KNApSAcK: C00038341
CAS: 10371-86-5
PMhub: MS000085168
LOTUS: LTS0095180

分类词条

Carbazole alkaloids

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

20 个相关的物种来源信息

4056 - Apocynaceae: LTS0095180
2759 - Eukaryota: LTS0095180
3398 - Magnoliopsida: LTS0095180
141590 - Ochrosia: LTS0095180
453912 - Ochrosia compta: 10.1021/JA01517A031
453912 - Ochrosia compta: LTS0095180
141591 - Ochrosia elliptica: 10.1016/S0021-9673(01)86824-2
141591 - Ochrosia elliptica: 10.1016/S0176-1617(85)80229-7
141591 - Ochrosia elliptica: 10.1021/JA01517A031
141591 - Ochrosia elliptica: 10.1021/NP50035A022
141591 - Ochrosia elliptica: LTS0095180
1619503 - Ochrosia moorei: 10.1021/NP070655E
1619503 - Ochrosia moorei: LTS0095180
453913 - Ochrosia sandwicensis: 10.1021/JA01517A031
453913 - Ochrosia sandwicensis: LTS0095180
453907 - Ochrosia vitiensis: 10.1016/S0031-9422(00)90020-7
453907 - Ochrosia vitiensis: LTS0095180
35493 - Streptophyta: LTS0095180
58023 - Tracheophyta: LTS0095180
33090 - Viridiplantae: LTS0095180

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Yao-Hao Xu, Wei Li, Yong Rao, Zhi-Shu Huang, Sheng Yin. Pyridocarbazole alkaloids from Ochrosia borbonica: lipid-lowering agents inhibit the cell proliferation and adipogenesis of 3T3-L1 adipocyte via intercalating into supercoiled DNA. Chinese journal of natural medicines. 2019 Sep; 17(9):663-671. doi: 10.1016/s1875-5364(19)30080-9. [PMID: 31526501]
Andreia Montoia, Luiz F Rocha E Silva, Zelina E Torres, David S Costa, Marycleuma C Henrique, Emerson S Lima, Marne C Vasconcellos, Rita C Z Souza, Monica R F Costa, Andriy Grafov, Iryna Grafova, Marcos N Eberlin, Wanderli P Tadei, Rodrigo C N Amorim, Adrian M Pohlit. Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog. Bioorganic & medicinal chemistry letters. 2014 Jun; 24(12):2631-4. doi: 10.1016/j.bmcl.2014.04.070. [PMID: 24813729]
Anthony R Carroll, Rama Addepalli, Gregory Fechner, Jill Smith, Gordon P Guymer, Paul I Forster, Ronald J Quinn. Alkaloids from the Australian rainforest tree Ochrosia moorei. Journal of natural products. 2008 Jun; 71(6):1063-5. doi: 10.1021/np070655e. [PMID: 18412397]
Angela A Salim, Mary J Garson, David J Craik. New indole alkaloids from the roots of Ochrosia acuminata. Journal of natural products. 2004 Oct; 67(10):1719-21. doi: 10.1021/np049812p. [PMID: 15497947]
G T Tan, J M Pezzuto, A D Kinghorn, S H Hughes. Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Journal of natural products. 1991 Jan; 54(1):143-54. doi: 10.1021/np50073a012. [PMID: 1710653]
R E Perdue. KB cell culture I. Role in discovery of antitumor agents from higher plants. Journal of natural products. 1982 Jul; 45(4):418-26. doi: 10.1021/np50022a010. [PMID: 7130986]
C Auclair, C Paoletti. Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. Journal of medicinal chemistry. 1981 Mar; 24(3):289-95. doi: 10.1021/jm00135a010. [PMID: 7265115]