Pentalenolactone (BioDeep_00000013424)

natural product

代谢物信息卡片

Pentalenolactone

化学式: C15H16O5 (276.0998)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 19.57%

分子结构信息

SMILES: CC1=CC23C(COC(=O)C24CO4)C(C(=O)O)=CC3C1C
InChI: InChI=1S/C15H16O5/c1-7-4-14-10(8(7)2)3-9(12(16)17)11(14)5-19-13(18)15(14)6-20-15/h3-4,8,10-11H,5-6H2,1-2H3,(H,16,17)/t8-,10-,11+,14-,15-/m1/s1

3D Structure

描述信息

A sesquiterpene lactone that is isolated from several Streptomyces species and exhibits antibiotic activity.

同义名列表

2 个代谢物同义名

Pentalenolactone; NSC136036

数据库引用编号

11 个数据库交叉引用编号

ChEBI: CHEBI:70816
KEGG: C20407
PubChem: 24199350
PubChem: 282522
LipidMAPS: LMPR0103740003
CAS: 31501-48-1
PMhub: MS000027879
MetaboLights: MTBLC70816
PubChem: 163312144
PDB-CCD: 7PT
LOTUS: LTS0254172

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

28 个相关的物种来源信息

2 - Bacteria: LTS0254172
1883 - Streptomyces:
1883 - Streptomyces: 10.1007/S10295-015-1685-7
1883 - Streptomyces: 10.1016/0378-1097(91)90494-U
1883 - Streptomyces: 10.1021/BI1019786
1883 - Streptomyces: 10.1021/JA111279H
1883 - Streptomyces: LTS0254172
29301 - Streptomyces arenae:
29301 - Streptomyces arenae: 10.1007/S10295-015-1685-7
29301 - Streptomyces arenae: 10.1016/0378-1097(91)90494-U
29301 - Streptomyces arenae: 10.1021/BI1019786
29301 - Streptomyces arenae: 10.1021/JA111279H
29301 - Streptomyces arenae: LTS0254172
33903 - Streptomyces avermitilis:
33903 - Streptomyces avermitilis: 10.1007/S10295-015-1685-7
33903 - Streptomyces avermitilis: 10.1016/0378-1097(91)90494-U
33903 - Streptomyces avermitilis: 10.1021/BI1019786
33903 - Streptomyces avermitilis: 10.1021/JA111279H
33903 - Streptomyces avermitilis: LTS0254172
42684 - Streptomyces collinus: 10.1007/S10295-015-1685-7
42684 - Streptomyces collinus: LTS0254172
1905 - Streptomyces exfoliatus: LTS0254172
66887 - Streptomyces filipinensis: 10.1007/S10295-015-1685-7
66887 - Streptomyces filipinensis: 10.1016/0378-1097(91)90494-U
66887 - Streptomyces filipinensis: 10.1021/BI1019786
66887 - Streptomyces filipinensis: 10.1021/JA111279H
66887 - Streptomyces filipinensis: LTS0254172
2062 - Streptomycetaceae: LTS0254172

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

M Ikeda, A Fukuda, M Takagi, M Morita, Y Shimada. Inhibitory effect of pentalenolactone on vascular smooth muscle cell proliferation. European journal of pharmacology. 2001 Jan; 411(1-2):45-53. doi: 10.1016/s0014-2999(00)00894-3. [PMID: 11137857]
B M Bakker, H V Westerhoff, F R Opperdoes, P A Michels. Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs. Molecular and biochemical parasitology. 2000 Feb; 106(1):1-10. doi: 10.1016/s0166-6851(99)00197-8. [PMID: 10743606]
K U Fröhlich, R Kannwischer, M Rüdiger, D Mecke. Pentalenolactone-insensitive glyceraldehyde-3-phosphate dehydrogenase from Streptomyces arenae is closely related to GAPDH from thermostable eubacteria and plant chloroplasts. Archives of microbiology. 1996 Mar; 165(3):179-86. doi: 10.1007/bf01692859. [PMID: 8599535]