Exact Mass: 255.14305180000002
Exact Mass Matches: 255.14305180000002
Found 476 metabolites which its exact mass value is equals to given mass value 255.14305180000002,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
DIMETHACHLOR
CONFIDENCE standard compound; EAWAG_UCHEM_ID 707 CONFIDENCE standard compound; INTERNAL_ID 8395 CONFIDENCE standard compound; INTERNAL_ID 3390
2-Amino-6-[(1R,2S)-1,2,3-trihydroxypropyl]-7,8-dihydro-3H-pteridin-4-one
7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases[1].
Diphenhydramine
Diphenhydramine is a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. -- Pubchem; Pseudoephedrine is a phenethylamine, and an isomer of ephedrine. Pseudoephedrine is the International Nonproprietary Name (INN) of the (1S,2S)- diastereomer of ephedrine (which has 1R,2S- configuration). Other names are (+)-pseudoephedrine and D-pseudoephedrine (Reynolds, 1989). The enantiomer (-)-(1R,2R)-Pseudoephedrine has fewer side-effects, fewer central nervous system (CNS) stimulatory effects, does not reduce to d-methamphetamine, yet retains its efficacy as a decongestant.[citation needed] However, the patent holder for (-)-Pseudoephedrine (Pfizer/Warner-Lambert) has not yet sought or received government approval for its sale to the public.(US Patent 6,495,529); Treatment for urinary incontinence is an unlabeled use for these medications. Unlabeled use means doctors can use the medication to treat a condition other than that for which it was first approved by the U.S. Food and Drug Administration (FDA). These medications are approved by the FDA for the treatment of nasal congestion caused by colds or allergies. However it has also been successful in treating stress incontinence by increasing the pressure (tension) exerted by the muscles of the bladder neck and the urethra, which helps retain the urine within the bladder. Despite being one of the oldest antihistamines on the market, it is by and large the most effective antihistamine available, either by prescription or over-the-counter, and has been shown to exceed the effectiveness of even the latest prescription drugs. Consequently, it is frequently used when an allergic reaction requires fast, effective reversal of the (often dangerous) effects of a massive histamine release. However, it is not always the drug of choice for treating allergies. Like many other first generation antihistamines, is also a potent anticholinergic agent. This leads to profound drowsiness as a very common side-effect, along with the possibilities of motor impairment (ataxia), dry mouth and throat, flushed skin, rapid or irregular heartbeat (tachycardia), blurred vision at near point due to lack of accommodation (cycloplegia), abnormal sensitivity to bright light (photophobia), pupil dilatation, urinary retention, constipation, difficulty concentrating, short-term memory loss, visual disturbances, hallucinations, confusion, erectile dysfunction, and delirium. -- Wikipedia;. A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. -- Pubchem; Pseudoephedrine is a phenethylamine, and an isomer of ephedrine. Pseudoephedrine is the International Nonproprietary Name (INN) of the (1S,2S)- diastereomer of ephedrine (which has 1R,2S- configuration). Other names are (+)-pseudoephedrine and D-pseudoephedrine (Reynolds, 1989). The enantiomer (-)-(1R,2R)-Pseudoephedrine has fewer side-effects, fewer central nervous system (CNS) stimulatory effects, does not reduce to d-methamphetamine, yet retains its efficacy as a decongestant.[citation needed] However, the patent holder for (-)-Pseudoephedrine (Pfizer/Warner-Lambert) has not yet sought or received government approval for its sale to the public.(US Patent 6,495,529); Treatment for urinary incontinence is an unlabeled use for these medications. Unlabeled use means doctors can use the medication to treat a condition other than that for which it was first approved by the U.S. Food and Drug Administration (FDA). These medications are approved by the FDA for the treatment of nasal congestion caused by colds or allergies. However it has also been successful in treating stress incontinence by increasing the pressure (tension) exerted by the muscles of the bladder neck and the urethra, which helps retain the urine within the bladder.; Despite being one of the oldest antihistamines on the market, it is by and large the most effective antihistamine available, either by prescription or over-the-counter, and has been shown to exceed the effectiveness of even the latest prescription drugs. Consequently, it is frequently used when an allergic reaction requires fast, effective reversal of the (often dangerous) effects of a massive histamine release. However, it is not always the drug of choice for treating allergies. Like many other first generation antihistamines, is also a potent anticholinergic agent. This leads to profound drowsiness as a very common side-effect, along with the possibilities of motor impairment (ataxia), dry mouth and throat, flushed skin, rapid or irregular heartbeat (tachycardia), blurred vision at near point due to lack of accommodation (cycloplegia), abnormal sensitivity to bright light (photophobia), pupil dilatation, urinary retention, constipation, difficulty concentrating, short-term memory loss, visual disturbances, hallucinations, confusion, erectile dysfunction, and delirium. -- Wikipedia [HMDB] D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AA - Aminoalkyl ethers D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics CONFIDENCE standard compound; EAWAG_UCHEM_ID 3352 D018926 - Anti-Allergic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) [1][2][3].
Tripelennamine
Tripelennamine is only found in individuals that have used or taken this drug. It is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically. [PubChem]Tripelennamine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AC - Substituted ethylene diamines D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D018926 - Anti-Allergic Agents
Ganciclovir
Ganciclovir is only found in individuals that have used or taken this drug. It is an acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections. [PubChem]Ganciclovirs antiviral activity inhibits virus replication. This inhibitory action is highly selective as the drug must be converted to the active form by a virus-encoded cellular enzyme, thymidine kinase (TK). TK catalyzes phosphorylation of ganciclovir to the monophosphate, which is then subsequently converted into the diphosphate by cellular guanylate kinase and into the triphosphate by a number of cellular enzymes. In vitro, ganciclovir triphosphate stops replication of herpes viral DNA. When used as a substrate for viral DNA polymerase, ganciclovir triphosphate competitively inhibits dATP leading to the formation of faulty DNA. This is where ganciclovir triphosphate is incorporated into the DNA strand replacing many of the adenosine bases. This results in the prevention of DNA synthesis, as phosphodiester bridges can longer to be built, destabilizing the strand. Ganciclovir inhibits viral DNA polymerases more effectively than it does cellular polymerase, and chain elongation resumes when ganciclovir is removed. J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AD - Antivirals D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C471 - Enzyme Inhibitor > C29575 - DNA Polymerase Inhibitor C254 - Anti-Infective Agent > C281 - Antiviral Agent KEIO_ID G088; [MS2] KO008989 KEIO_ID G088 Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain[1][2][3].
DIMETHAMETRYN
C11H21N5S (255.15175860000002)
The sample was injected by direct infusion.; This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 19HP8024 to the Mass Spectrometry Society of Japan. CONFIDENCE standard compound; INTERNAL_ID 287; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9072; ORIGINAL_PRECURSOR_SCAN_NO 9070 CONFIDENCE standard compound; INTERNAL_ID 287; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9090; ORIGINAL_PRECURSOR_SCAN_NO 9088 CONFIDENCE standard compound; INTERNAL_ID 287; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9113; ORIGINAL_PRECURSOR_SCAN_NO 9108 CONFIDENCE standard compound; INTERNAL_ID 287; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9089; ORIGINAL_PRECURSOR_SCAN_NO 9087 CONFIDENCE standard compound; INTERNAL_ID 287; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9055; ORIGINAL_PRECURSOR_SCAN_NO 9052 CONFIDENCE standard compound; INTERNAL_ID 287; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9033; ORIGINAL_PRECURSOR_SCAN_NO 9032
Nicotinamide riboside
Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside was originally identified as a nutrient in milk. It is a useful compound for the elevation of NAD+ levels in humans. Nicotinamide riboside has recently been discovered to be an NAD(+) precursor that is converted into nicotinamide mononucleotide by specific nicotinamide riboside kinases, Nrk1 and Nrk2. It has been shown that exogenous nicotinamide riboside promotes Sir2-dependent repression of recombination, improves gene silencing, and extends the lifespan of certain animal models without calorie restriction (PMID: 17482543). Supplementation in mammalian cells and mouse tissues increases NAD(+) levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high-fat diet-induced metabolic abnormalities (PMID: 22682224). Recent data suggest that nicotinamide riboside may be the only vitamin precursor that supports neuronal NAD+ synthesis (PMID: 18429699). Nicotinamide riboside kinase has an essential role in the phosphorylation of nicotinamide riboside and the cancer drug tiazofurin (PMID: 15137942). Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside has been identified as a nutrient in milk. It is a useful compound for elevation of NAD+ levels in humans. Recent data suggest that nicotinamide riboside may be the only vitamin precursor that supports neuronal NAD+ synthesis (PMID: 18429699). Nicotinamide riboside kinase has an essential role for phosphorylation of nicotinamide riboside and the cancer drug tiazofurin (PMID 15137942). [HMDB] COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map C26170 - Protective Agent > C275 - Antioxidant Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
6-(1,2,3,4-Tetrahydro-6-methoxy-2-naphthyl)-2(1H)-pyridone
C16H17NO2 (255.12592220000002)
1-Methyl-6-(1,2,3,4-tetrahydro-6-hydroxy-2-naphthyl)-2(1H)-pyridone
C16H17NO2 (255.12592220000002)
Pyrrolysine
A N(6)-acyl-L-lysine having a (2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-ylcarboxy group at the N(6)-position.
7,8-Dihydroneopterin
7,8-Dihydroneopterin, also known as dihydroneopterin, belongs to the class of organic compounds known as biopterins and derivatives. These are coenzymes containing a 2-amino-pteridine-4-one derivative. They are synthesized in several parts of the body, including the pineal gland. 7,8-Dihydroneopterin is a strong basic compound (based on its pKa). Within humans, 7,8-dihydroneopterin participates in a number of enzymatic reactions. In particular, 7,8-dihydroneopterin can be biosynthesized from sepiapterin; which is catalyzed by the enzyme sepiapterin reductase or carbonyl reductase [NADPH] 1. In humans, 7,8-dihydroneopterin is involved in the metabolic disorder called hyperphenylalaninemia due to 6-pyruvoyltetrahydropterin synthase (PTPS) deficiency. 7,8-Dihydroneopterin is produced by human monocyte-derived macrophages upon stimulation with interferon-gamma. Increased amounts of 7,8-dihydroneopterin in human body fluids are found in many disorders, including viral infections and autoimmune diseases (PMID: 12804528). 7,8-dihydroneopterin, also known as npr, belongs to biopterins and derivatives class of compounds. Those are coenzymes containing a 2-amino-pteridine-4-one derivative. They are mainly synthesized in several parts of the body, including the pineal gland. 7,8-dihydroneopterin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 7,8-dihydroneopterin can be found in a number of food items such as prickly pear, star anise, cocoa bean, and black salsify, which makes 7,8-dihydroneopterin a potential biomarker for the consumption of these food products. 7,8-dihydroneopterin exists in all living organisms, ranging from bacteria to humans. In humans, 7,8-dihydroneopterin is involved in the pterine biosynthesis. 7,8-dihydroneopterin is also involved in several metabolic disorders, some of which include hyperphenylalaninemia due to dhpr-deficiency, sepiapterin reductase deficiency, dopa-responsive dystonia, and hyperphenylalaniemia due to guanosine triphosphate cyclohydrolase deficiency. 7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases[1].
Diethylenetriamine crosslinked with epichlorohydrin
C14H22ClNO (255.13898319999998)
Diethylenetriamine crosslinked with epichlorohydrin is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]")
Phenyltoloxamine
C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist Phenyltoloxamine is a first-generation ethanolamine H1-antihistamine.
Atomoxetine
Atomoxetine is the first non-stimulant drug approved for the treatment of attention-deficit hyperactivity disorder (ADHD). It is sold in the form of the hydrochloride salt of atomoxetine. This chemical is manufactured and marketed under the brand name Strattera; by Eli Lilly and Company and as a generic Attentin by Torrent Pharmaceuticals. There is currently no generic available within the United States due to patent restrictions. [Wikipedia] N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C185721 - Norepinephrine Reuptake Inhibitor C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D049990 - Membrane Transport Modulators
N-Methylschinifoline
C16H17NO2 (255.12592220000002)
N-Methylschinifoline is found in fruits. N-Methylschinifoline is an alkaloid from roots of Zanthoxylum simulans (Szechuan pepper). Alkaloid from roots of Zanthoxylum simulans (Szechuan pepper). N-Methylschinifoline is found in herbs and spices and fruits.
Hydroxybupropion
Hydroxybupropion is found in the bupropion degradation pathway. Bupropion reacts with NADPH and O2 to produce hydroxybupropion, with NADP+ and H2O as byproducts. [HMDB] Hydroxybupropion is found in the bupropion degradation pathway. Bupropion reacts with NADPH and O2 to produce hydroxybupropion, with NADP+ and H2O as byproducts.
N-Demethyl orphenadrine
N-Demethyl orphenadrine is a metabolite of orphenadrine. Orphenadrine is an anticholinergic drug of the ethanolamine antihistamine class with prominent CNS and peripheral actions used to treat painful muscle spasms, other similar conditions, as well as the treatment of some aspects of Parkinsons Disease. It is closely related to diphenhydramine. Therefore, it is related to other drugs used for Parkinsons like benztropine and trihexyphenidyl, and it is also structurally related to nefopam, which is a centrally-acting yet non-opioid analgesic. (Wikipedia) C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
(2R)-2-(Tert-butylamino)-1-(3-chlorophenyl)-3-hydroxypropan-1-one
6-(4-Methoxyphenyl)-2-methyl-7H-imidazo[1,2-a]pyrazin-3-one
C14H13N3O2 (255.10077180000002)
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
2-Methoxyphenylmetyrapone
C16H17NO2 (255.12592220000002)
9-(4-Fluoro-3-(hydroxymethyl)butyl)guanine
C10H14FN5O2 (255.11314760000002)
Maoto
C16H17NO2 (255.12592220000002)
1-(3-Chloro-4-hydroxyphenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
Alaproclate
N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants > N06AB - Selective serotonin reuptake inhibitors D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent D049990 - Membrane Transport Modulators
Coumarin 102
C16H17NO2 (255.12592220000002)
2-Amino-7-[(2R)-2,3-dihydroxypropanoyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
C16H17NO2 (255.12592220000002)
7,8-dihydromonapterin
7,8-dihydromonapterin, also known as dhm or h2-mpt, belongs to biopterins and derivatives class of compounds. Those are coenzymes containing a 2-amino-pteridine-4-one derivative. They are mainly synthesized in several parts of the body, including the pineal gland. 7,8-dihydromonapterin is slightly soluble (in water) and an extremely strong acidic compound (based on its pKa). 7,8-dihydromonapterin can be found in a number of food items such as mugwort, pineapple, eggplant, and japanese pumpkin, which makes 7,8-dihydromonapterin a potential biomarker for the consumption of these food products.
(S)-N-(1-Hydroxymethyl-2-phenylethyl)-benzamide
C16H17NO2 (255.12592220000002)
2-[(tert-butoxycarbonyl)amino]-3-(1H-imidazol-4-yl)propanoic acid
N-Benzoyl-L-phenylalaninol
C16H17NO2 (255.12592220000002)
A member of the class of benzamides resulting from the formal condensation of the carboxy group of benzoic acid with the amino group of L-phenylalaninol.
helibracteatinine|O7-Angeloyl-(1R,7S,8S)-1-Hydroxymethyl-1,7-pyrrolizidinediol
2-Methylpropylamide-(2E,6E,8Z)-2,6,8-Tridecatriene-10,12-diynoic acid|trideca-2t,6t,8c-trien-10,12-diynoic acid (2-methylbutyl)amide
N-isobutyl-4-hexanoyl-4-hydroxypyrrolidin-1-one|pipercycliamide
longipenamide B|N-isobutyl-syn-6,9-dihydroxy-2E,7E-decadienamide
longipenamide A|N-isobutyl-syn-8,9-dihydroxy-2E,6Z-decadienamide
3-hydroxy-7-isobutyl-6-methyl-hexahydro-pyrazino[1,2-b]pyridazine-5,8-dione
Onosmin B
C16H17NO2 (255.12592220000002)
A benzoate ester obtained by the fromal condensation of the carboxy group of onosmin A with methanol. Isolated from Onosma hispida, it exhibits inhibitory activity against lipoxygenase.
3-ethoxy-8-methoxy-4-vinyl-4,4a,5,6,7,8-hexahydro-3H-pyrano[3,4-c]pyridin-8-ol|3-ethoxy-8-methoxy-4-vinyl-4,4a,5,6-tetrahydro-3H-pyrano[3,4-c]pyridine; hydrate
Atomoxetine
N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C185721 - Norepinephrine Reuptake Inhibitor C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D049990 - Membrane Transport Modulators CONFIDENCE standard compound; EAWAG_UCHEM_ID 2846
diphenhydramine
D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AA - Aminoalkyl ethers D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D018926 - Anti-Allergic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE standard compound; INTERNAL_ID 2671 CONFIDENCE standard compound; INTERNAL_ID 8588 CONFIDENCE standard compound; INTERNAL_ID 4116 Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) [1][2][3].
tripelennamine
D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AC - Substituted ethylene diamines D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D018926 - Anti-Allergic Agents
Boc-His-OH
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.281 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.283 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.275 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.276
N-(1-hydroxy-3-phenylpropan-2-yl)benzamide
C16H17NO2 (255.12592220000002)
C10-homoserine lactone
CONFIDENCE standard compound; INTERNAL_ID 204
Diphenydramine
Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) [1][2][3].
N-(1-hydroxy-3-phenylpropan-2-yl)benzamide [IIN-based: Match]
C16H17NO2 (255.12592220000002)
Tofenacin
C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
Phenyltoloxamine
C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
Alaproclate
N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants > N06AB - Selective serotonin reuptake inhibitors D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent D049990 - Membrane Transport Modulators
Iversal
C14H22ClNO (255.13898319999998)
R - Respiratory system > R05 - Cough and cold preparations > R05D - Cough suppressants, excl. combinations with expectorants C78273 - Agent Affecting Respiratory System > C66917 - Antitussive Agent D019141 - Respiratory System Agents > D000996 - Antitussive Agents D002491 - Central Nervous System Agents
N-Methylschinifoline
C16H17NO2 (255.12592220000002)
TERT-BUTYL 2-(TERT-BUTYL)-4-OXOPIPERIDINE-1-CARBOXYLATE
Quinoline-3-boronic acid pinacol ester
C15H18BNO2 (255.14305180000002)
3,5-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
Cloforex
C78272 - Agent Affecting Nervous System > C29728 - Anorexiant
N-[[2-chloro-5-(2-methoxyethoxy)phenyl]methyl]cyclopropanamine
(S)-4-(tert-Butoxycarbonylamino)-2,6-dimethyl-1-hepten-3-one
4-tert-butyl-2-(2,5-difluorophenyl)morpholine
C14H19F2NO (255.14346279999998)
TERT-BUTYL 3-[5-(2-AMINO-ETHYL)-THIOPHEN-3-YL]-PROPIONATE
tert-butyl N-[4-fluoro-2-(1-hydroxyethyl)phenyl]carbamate
C13H18FNO3 (255.12706500000002)
ethyl 4-methyl-2-piperazin-1-yl-1,3-thiazole-5-carboxylate
2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetic acid
3-(diethylcarbamoyl)-1,2,2-trimethyl-cyclopentane-1-carboxylic acid
cis-2-Benzylaminomethyl-1-cyclohexanol hydrochloride
C14H22ClNO (255.13898319999998)
(R)-2-ALLYL-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID
N-[2-(Dimethylamino)phenyl]-N,N-dimethyl-1,2-benzenediamine
Methyl 1-benzylpyrrolidine-3-carboxylate hydrochloride
tert-Butyl 4-((1R,2S)-2-(hydroxymethyl)cyclopropyl)piperidine-1-carboxylate
tert-butyl 2-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate
tert-butyl 2-oxa-9-azaspiro[5.5]undecane-9-carboxylate
9-Oxa-2-azaspiro[5.5]undecan-9-carboxylic acid tert-butyl ester
4-CYANO-TRANS-BETA-STYRYLBORONIC ACID PINACOL ESTER
C15H18BNO2 (255.14305180000002)
Hydrazinecarbothioamide,N-[2-(3,4-dimethoxyphenyl)ethyl]-
3-(4-HYDROXYPHENYL)N-BENZYLPROPIONAMIDE&
C16H17NO2 (255.12592220000002)
Quinpirole hydrochloride
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists C78272 - Agent Affecting Nervous System > C66884 - Dopamine Agonist Quinpirole Hydrochloride ((-)-LY 171555) is a high-affinity agonist of dopamine D2/D3 receptor.
4-cyclohexyloxypyridine-2-carboximidamide,hydrochloride
C12H18ClN3O (255.11383279999998)
6-cyclohexyloxypyridine-2-carboximidamide,hydrochloride
C12H18ClN3O (255.11383279999998)
N-TERT-BUTOXYCARBONYL-2-AMINOMETHYL-IMIDAZOLE-4-CARBOXYLIC ACID METHYL ESTER
2-(2-ISOPROPYL-PHENYLAMINO)-BENZOIC ACID
C16H17NO2 (255.12592220000002)
1-tert-Butyl 3-ethyl 5,6-dihydropyridine-1,3(2H)-dicarboxylate
(2S,4S)-4-ALLYL-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID
7-TERT-BUTYL 2-METHYL 7-AZABICYCLO[2.2.1]HEPTANE-2,7-DICARBOXYLATE
ethyl 2,6-dimethyl-4-phenylpyridine-3-carboxylate
C16H17NO2 (255.12592220000002)
3-AMINO-3-(2,4,6-TRIMETHOXY-PHENYL)-PROPIONIC ACID
C12H17NO5 (255.11066720000002)
3-AMINO-4,4-DIPHENYL-BUTANOIC ACID
C16H17NO2 (255.12592220000002)
4-(4-methylpiperidin-1-yl)quinazoline-6-carbaldehyde
4-hydroxy-3-(morpholin-4-ylmethyl)benzoic acid,hydrate
C12H17NO5 (255.11066720000002)
1-BENZYL-PIPERIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE
[4-(dimethylamino)phenyl]-(4-methoxyphenyl)methanone
C16H17NO2 (255.12592220000002)
(3AR,5R,6AS)-2-(TERT-BUTOXYCARBONYL)OCTAHYDROCYCLOPENTA[C]PYRROLE-5-CARBOXYLIC ACID
{3-[(4-Methylphenyl)carbamoyl]phenyl}boronic acid
C14H14BNO3 (255.10666840000002)
Tert-Butyl 1-oxo-2-oxa-8-azaspiro[4.5]decane-8-carboxylate
(4AS,8AS)-2-BENZOYL-1,3,4,4A,5,8A-HEXAHYDRO-6(2H)-ISOQUINOLINONE
C16H17NO2 (255.12592220000002)
6,7-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinoline hydrochloride
Trimethylsilanyl-(2-trimethylsilanyloxy-pyrimidin-4-yl)-amine
1-Benzylpiperidine-3-carboxylic acid hydrochloride
hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-tert-butyl ester
ETHYL 3-(3-CHLORO-PHENYL)-2-METHYLAMINOMETHYL-PROPIONATE
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate
C9H22NO5P (255.12355319999998)
N-(tert-Butoxycarbonyl)-3-(2-furyl)-L-alanine
C12H17NO5 (255.11066720000002)
1-(4-butylphenyl)-2,5-dimethylpyrrole-3-carbaldehyde
3-(Dimethoxymethyl)-5-methoxy-4-(trimethylsilyl)pyridine
(S)-2-((TERT-BUTOXYCARBONYL)AMINO)-3-(1H-PYRAZOL-1-YL)PROPANOIC ACID
(1R,2S)-1-[[(tert-Butoxy)carbonyl]amino]-2-ethenyl-cyclopropanecarboxylic acid ethyl ester
(1R,2S)-(+)-2-AMINOCYCLOHEX-3-ENECARBOXYLICACIDHYDROCHLORIDE
2-Fluoro-5-methylpyridine-4-boronic acid pinacol ester
R(+)-3-(3-HYDROXYPHENYL)-N-PROPYLPIPERIDINE HYDROCHLORIDE
C14H22ClNO (255.13898319999998)
(R)-Preclamol hydrochloride ((+)-3-PPP hydrochloride) is the R-enantiomer of Preclamol hydrochloride. (R)-Preclamol hydrochloride is a DA agonist with autoreceptor as well as postsynaptic receptor stimulatory properties[1][2].
PRECLAMOL HYDROCHLORIDE
C14H22ClNO (255.13898319999998)
Preclamol hydrochloride ((-)-3-PPP hydrochloride) is a selective dopamine autoreceptor agonist. Preclamol hydrochloride has the potential for the research of schizophrenia[1][2].
1-(2-FLUORO-PHENYL)-2-HYDROXY-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
C13H18FNO3 (255.12706500000002)
(1-Furan-2-yl-ethyl)-(3-methyl-1-phenyl-but-3-enyl)-amine
3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ANILINE HYDROCHLORIDE
3-Benzo[1,3]dioxol-5-yl-3-phenyl-propylamine
C16H17NO2 (255.12592220000002)
N-[4,5,6,7-Tetrahydrobenzimidazole-5-yl)carbonyl] pyrrolidine sulfate
C12H18ClN3O (255.11383279999998)
[3-(Benzylcarbamoyl)phenyl]boronic acid
C14H14BNO3 (255.10666840000002)
4-Methoxy-1-(triisopropylsilyl)-1H-pyrrolo[2,3-c]pyridine
[4-(Benzylcarbamoyl)phenyl]boronic acid
C14H14BNO3 (255.10666840000002)
4-Methoxy-alpha-methyl-N-(phenylmethyl)benzeneethanamine
tert-Butyl 4-(2-methoxy-2-oxoethylidene)piperidine-1-carboxylate
tert-butyl 2,6-diethyl-4-oxopiperidine-1-carboxylate
5-(tert-butyl)-2-methyl-1-[2-(methylthio)ethyl]-1H-pyrrole-3-carboxylic acid
8-methoxy-N-propyl-2-aminotetraline hydrochloride
C14H22ClNO (255.13898319999998)
7-methoxy-N-propyl-2-aminotetraline hydrochloride
C14H22ClNO (255.13898319999998)
6-methoxy-N-propyl-2-aminotetraline hydrochloride
C14H22ClNO (255.13898319999998)
(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine hydrochloride
C14H22ClNO (255.13898319999998)
8-(tert-Butoxycarbonyl)-8-azabicyclo[3.2.1]octane-3-carboxylic acid
RaceMic 2-Aza-bicyclo[2.2.2]octane-2,6-dicarboxylic acid 2-tert-butyl ester
3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.2.1]octane-8-carboxylic acid
1H-Pyrrolo[2,3-b]pyridine-5-methanamine,3-fluoro-(9CI)
4-(5-AMINO-1H-BENZOIMIDAZOL-2-YL)-2-METHOXY-PHENOL
C14H13N3O2 (255.10077180000002)
Quinoline-4-boronic acid pinacol ester
C15H18BNO2 (255.14305180000002)
(1R,2S)-ethyl 1-(tert-butoxycarbonylamino)-2-vinylcyclopropanecarboxylate
ISOPROPYL 4-AMINO-[1,1-BIPHENYL]-4-CARBOXYLATE
C16H17NO2 (255.12592220000002)
1-[(4-methoxyphenyl)methyl]-2H-pyrazolo[3,4-b]pyridin-4-one
C14H13N3O2 (255.10077180000002)
5-CYANO-1-P-TOLYL-1H-PYRAZOLE-4-CARBOXYLICACIDETHYLESTER
C14H13N3O2 (255.10077180000002)
1-boc-amino-2-vinylcyclopropanecarboxylic acid ethyl ester
4-N-Boc-amino-3-fluorophenylboronic acid
C11H15BFNO4 (255.10781120000001)
9-(4-Fluoro-3-(hydroxymethyl)butyl)guanine
C10H14FN5O2 (255.11314760000002)
Furan-2-ylmethyl-(3-methyl-1-p-tolyl-but-3-enyl)-amine
N-[1-(4-fluorophenyl)-2-methylpropan-2-yl]-1-phenylmethanimine
6-(Diethylamino)-4-hydroxy-8-methyl-3-quinolinecarbonitrile
2-Methyl-2-propanyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octan e-5-carboxylate
2-Methyl-2-propanyl 4,4-dimethyl-1-oxa-7-azaspiro[4.4]nonane-7-ca rboxylate
1-(3-Hydroxyphenyl)-2-[methyl(phenylmethyl)amino]ethan-1-one
C16H17NO2 (255.12592220000002)
3-AMINO-3-(2,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID
C12H17NO5 (255.11066720000002)
4-Isoquinolineboronic acid pinacol ester
C15H18BNO2 (255.14305180000002)
Methyl (2S)-1-(1,2-dioxo-3,3-dimethypentyl)-2-pyrrolidinecarboxylate
(2R)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine,hydrochloride
C14H22ClNO (255.13898319999998)
2-Methyl-2-propanyl 2-formyl-1-oxa-7-azaspiro[3.5]nonane-7-carbox ylate
1-Oxa-7-azaspiro[4.5]decane-7-carboxylic acid, 3-oxo-, 1,1-dimethylethyl ester
tert-butyl 1-oxo-2-oxa-9-azaspiro[4.5]decane-9-carboxylate
(1R,3AS,6AR)-2-(TERT-BUTOXYCARBONYL)OCTAHYDROCYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID
(R)-(+)-7-methoxy-N-propyl-2-aminotetraline hydrochloride
C14H22ClNO (255.13898319999998)
(R)-8-methoxy-N-propyl-2-aminotetraline hydrochloride
C14H22ClNO (255.13898319999998)
tert-butyl N-[[4-(chloromethyl)phenyl]methyl]carbamate
3-AMINO-4-CYANO-1-PHENYL-1H-PYRROLE-2-CARBOXYLIC ACID ETHYL ESTER
C14H13N3O2 (255.10077180000002)
(3,4-DIMETHYLPHENYLAMINO)PHENYLACETICACID
C16H17NO2 (255.12592220000002)
6-(tert-Butoxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid
[3-(piperidin-1-ylmethyl)phenyl]boronic acid,hydrochloride
3-Oxa-9-azaspiro[5.5]undecan-9-carboxylic acid tert-butyl ester
(R)-4-CYANO-THIAZOLIDINE-3-CARBOXYLIC ACID TERT-BUTYL ESTER
(S)-TERT-BUTYL 2-((1R,2S)-1-HYDROXY-2-METHYLBUT-3-EN-1-YL)PYRROLIDINE-1-CARBOXYLATE
(S)-(-)-7-methoxy-N-propyl-2-aminotetraline hydrochloride
C14H22ClNO (255.13898319999998)
(S)-8-methoxy-N-propyl-2-aminotetraline hydrochloride
C14H22ClNO (255.13898319999998)
2-Amino-6,7-dihydro-5H-thiazolo[5,4-b]pyridine-4-carboxylic acid tert-butyl ester
4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonitrile
C12H12F3N3 (255.09832679999997)
[2-[(N,3-dimethylanilino)methyl]phenyl]boronic acid
C15H18BNO2 (255.14305180000002)
ethyl 2-[(4-chlorophenyl)methyl]-3-(methylamino)propanoate
1-Propanone,3-(4-morpholinyl)-1-phenyl-, hydrochloride (1:1)
2-[2-Hydroxy-5-(2-hydroxyethyl)phenyl]-2H-benzotriazole
C14H13N3O2 (255.10077180000002)
(S)-2-(2-METHYLBENZYL)PYRROLIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE
(S)-2-ALLYL-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID
3-amino-N-(2,4,6-trimethylphenyl)pyridine-4-carboxamide
1-methyl-4-phenylpiperidine-4-carboxylic acid,hydrochloride
Quinoline-8-boronic acid pinacol ester
C15H18BNO2 (255.14305180000002)
1-(6-Morpholinopyridin-3-yl)cyclopropanamine hydrochloride
C12H18ClN3O (255.11383279999998)
1-Methyl-4-(4-piperidyl)piperazine Dihydrochloride
C10H23Cl2N3 (255.12689379999998)
(2S)-2-amino-3-methyl-1,1-diphenylbutan-1-ol (en)Benzenemethanol, .α.-(1-amino-2-methylpropyl)-.α.-phenyl- (en)
methyl 2-(benzylamino)-2-phenylacetate
C16H17NO2 (255.12592220000002)
7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline
C15H18BNO2 (255.14305180000002)
5-CYANO-1-P-TOLYL-1H-PYRAZOLE-3-CARBOXYLICACIDETHYLESTER
C14H13N3O2 (255.10077180000002)
tert-butyl 2-(hydroxymethyl)-7-azaspiro[3.5]nonane-7-carboxylate
tert-butyl 3-hydroxy-3-(trifluoromethyl)pyrrolidine-1-carboxylate
4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzaldehyde
C16H17NO2 (255.12592220000002)
5-Quinolineboronic Acid Pinacol Ester
C15H18BNO2 (255.14305180000002)
tert-butyl 2,4-dioxo-1,3,7-triazaspiro[4.4]nonane-7-carboxylate
tert-butyl naphthalen-1-ylmethylenecarbamate
C16H17NO2 (255.12592220000002)
(S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine Hydrochloride
C14H22ClNO (255.13898319999998)
3-(4-tert-Butoxy-phenyl)-pyrrolidine hydrochloride
C14H22ClNO (255.13898319999998)
2-tert-Butoxycarbonylamino-3-(1H-imidazol-2-yl)-propionic acid
N-(5-Benzyloxy-2-methyl-phenyl)-acetamide
C16H17NO2 (255.12592220000002)
3-Azabicyclo[3.1.0]hexane-3,6-dicarboxylic acid 3-(tert-butyl) 6-ethyl ester
N-(2,4-Dimethylphenyl)-4-Methoxybenzamide
C16H17NO2 (255.12592220000002)
4-(2-Methyl-benzyloxyMethyl)-piperidine hydrochloride
C14H22ClNO (255.13898319999998)
(2,3-difluoro-4-(4-Methylpiperidin-1-yl)phenyl)boronic acid
2-Ethyl-6-methylpyridin-3-ol succinate
C12H17NO5 (255.11066720000002)
6-{[(tert-butoxy)carbonyl]amino}spiro[3.3]heptane-2-carboxylic acid
4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline
(2S,3aS,6aS)-1-(tert-butoxycarbonyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid
(3,5-DIMETHYLPHENYLAMINO)PHENYLACETICACID
C16H17NO2 (255.12592220000002)
N-(3,5-dimethylphenyl)-2-(4-hydroxyphenyl)acetamide
C16H17NO2 (255.12592220000002)
1-ETHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
N6-Trifluoroacetyl-L-lysyl-L-proline
C12H18ClN3O (255.11383279999998)
3-AMINO-3-(3,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID
C12H17NO5 (255.11066720000002)
2-(Benzylcarbamoyl)benzeneboronic acid
C14H14BNO3 (255.10666840000002)
N-(4-Chloro-2-ethoxyphenyl)-2,2-dimethylpropanamide
5-(Benzyloxy)-4-fluoro-2-methyl-1H-indole
C16H14FNO (255.10593659999998)
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline
C15H18BNO2 (255.14305180000002)
(S)-2-(3-METHYLBENZYL)PYRROLIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE
N-(6-formylnaphthalen-2-yl)-2,2-dimethylpropanamide
C16H17NO2 (255.12592220000002)
3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester
METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE
6-(2,2-Dicyanovinyl)-N-(2-hydroxyethyl)-1,2,3,4-tetrahydroquinoline
[2-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]methanamine
C12H12F3N3 (255.09832679999997)
tert-butyl 2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
6-Quinolineboronic acid pinacol ester
C15H18BNO2 (255.14305180000002)
alpha-Phenyl-2-piperidineacetic acid hydrochloride
2-Chloro-N-(2,6-diethylphenyl)-N-(hydroxymethyl)acetamide
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
C16H17NO2 (255.12592220000002)
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-, (1R)-
C16H17NO2 (255.12592220000002)
4-(3-Aminoimidazo[1,2-a]pyridin-2-yl)-2-methoxyphenol
C14H13N3O2 (255.10077180000002)
N-[[(6-methyl-2-pyridinyl)amino]-oxomethyl]benzamide
C14H13N3O2 (255.10077180000002)
N-[(E)-(4-methylphenyl)methylideneamino]-2-(1-methylpyrrol-2-yl)acetamide
8-Methyl-2-(3-methylbutyl)-1,2,4-triazaspiro[4.5]decane-3-thione
(1S)-2,3,4,5-Tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol
C16H17NO2 (255.12592220000002)
4-Amino-2-(butylthio)-5-pyrimidinecarboxylic acid ethyl ester
5-methyl-N-(4-propan-2-ylphenyl)-2-pyrazinecarboxamide
N-[(3S)-2-Oxotetrahydrofuran-3-yl]-3-oxononanamide
Clobutinol
C14H22ClNO (255.13898319999998)
R - Respiratory system > R05 - Cough and cold preparations > R05D - Cough suppressants, excl. combinations with expectorants C78273 - Agent Affecting Respiratory System > C66917 - Antitussive Agent D019141 - Respiratory System Agents > D000996 - Antitussive Agents D002491 - Central Nervous System Agents
(2S)-2-azaniumyl-6-({[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}amino)hexanoate
chanoclavine-I aldehyde(1+)
C16H19N2O+ (255.14973039999998)
An indole alkaloid cation that is the conjugate acid of chanoclavine-I aldehyde obtained by protonation of the secondary amino group. Major species at pH 7.3
[(6aR,10aR)-7-methyl-4,6,6a,7,8,10a-hexahydroindolo[4,3-fg]quinolin-7-ium-9-yl]methanol
C16H19N2O+ (255.14973039999998)
N(2)-[(2E)-3-methylhex-2-enoyl]-L-glutaminate
C12H19N2O4- (255.13447539999999)
5-Hydroxy-3,6-bis(2-methylpropyl)-1,4-dioxidopyrazin-4-ium-2-one
C12H19N2O4- (255.13447539999999)
2-Amino-7-[(2R)-2,3-dihydroxypropanoyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one
N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]benzamide
C16H17NO2 (255.12592220000002)
N-(2-methoxybenzyl)-9H-purin-6-amine
C13H13N5O (255.11200480000002)
N-(1H-benzimidazol-2-yl)-3-(1-imidazolyl)propanamide
C13H13N5O (255.11200480000002)
N1-phenyl-2-[imino(2-pyridyl)methyl]hydrazine-1-carboxamide
C13H13N5O (255.11200480000002)
2-Amino-5-ethyl-4-(2-furanyl)-6-propyl-3-pyridinecarbonitrile
2-[(2E)-2-(1-Pyridin-4-ylethylidene)hydrazinyl]benzoic acid
C14H13N3O2 (255.10077180000002)
N-(3-ethylphenyl)-2-phenoxyacetamide
C16H17NO2 (255.12592220000002)
N-tert-butyl-2-(4-chloro-3-methylphenoxy)acetamide
5-(methoxymethyl)-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
C14H13N3O2 (255.10077180000002)
[(6R,7S)-6,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (E)-2-methylbut-2-enoate
3-[1-(dimethylamino)-1H-pyrrol-2-yl]-2-(2-furylcarbonyl)acrylonitrile
C14H13N3O2 (255.10077180000002)
N-[(4E,8E)-1,3-dihydroxydodeca-4,8-dien-2-yl]acetamide
3,5-Dimethyl-4-[(1-oxotetralin-2-yl)methyl]isoxazole
C16H17NO2 (255.12592220000002)
ganciclovir
An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections. J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AD - Antivirals D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C471 - Enzyme Inhibitor > C29575 - DNA Polymerase Inhibitor C254 - Anti-Infective Agent > C281 - Antiviral Agent Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain[1][2][3].
Nicotinamide riboside
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map C26170 - Protective Agent > C275 - Antioxidant Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
7,8-Dihydroneopterin
A neopterin where positions C-7 and C-8 have been hydrogenated. 7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases[1].
N~6~-{[(2s,3s)-3-Methyl-3,4-Dihydro-2h-Pyrrol-2-Yl]carbonyl}-L-Lysine
N-Ribosylnicotinamide
A pyridine nucleoside consisting of nicotinamide with a beta-D-ribofuranosyl moiety at the 1-position.
(S)-UFR2709 (hydrochloride)
(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist?and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction[1][2].
IM176OUT05
C11H18ClN5 (255.12506580000002)
IM176OUT05 is a high solubility biguanide. IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2?μM[1].
1-(1-methylpyrrolidin-2-yl)-6-phenylhexa-3,5-dien-2-one
(5s)-5-hexanoyl-5-hydroxy-1-(2-methylpropyl)pyrrolidin-2-one
(1r,3s,5s,6r,7r)-6,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2e)-2-methylbut-2-enoate
n-benzyl-3-(4-hydroxyphenyl)propanimidic acid
C16H17NO2 (255.12592220000002)
n-[(2s)-1-hydroxy-3-phenylpropan-2-yl]benzenecarboximidic acid
C16H17NO2 (255.12592220000002)
5-hexanoyl-5-hydroxy-1-(2-methylpropyl)pyrrolidin-2-one
4,5-dihydroxy-1-methyl-7-(2-methylpropyl)-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one
C12H17NO5 (255.11066720000002)
(1s,7r,7as)-7-hydroxy-7-(hydroxymethyl)-hexahydropyrrolizin-1-yl (2z)-2-methylbut-2-enoate
(1r,4r,7r,8r)-4,5-dihydroxy-1-methyl-7-(2-methylpropyl)-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one
C12H17NO5 (255.11066720000002)
(2,7-dihydroxy-hexahydro-1h-pyrrolizin-1-yl)methyl 2-methylbut-2-enoate
(1r,3r,5s,6s,7r)-6,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2e)-2-methylbut-2-enoate
(1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one
C12H17NO5 (255.11066720000002)
7-hydroxy-7-(hydroxymethyl)-hexahydropyrrolizin-1-yl 2-methylbut-2-enoate
1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-(c-hydroxycarbonimidoyl)-1λ⁵-pyridin-1-ylium
(1s,2r)-1-(4-hydroxy-2-imino-7,8-dihydro-1h-pteridin-6-yl)propane-1,2,3-triol
(8r,9r)-8,9-dihydroxy-n-(2-methylpropyl)deca-2,6-dienimidic acid
7-(3-methylbut-2-en-1-yl)-3-(2-oxopropylidene)-1h-indol-2-one
C16H17NO2 (255.12592220000002)
7-(chloromethyl)-2,3,5,7a-tetrahydro-1h-pyrrolizin-1-yl 2-methylbut-2-enoate
n-[2-(4-methoxyphenyl)ethyl]benzenecarboximidic acid
C16H17NO2 (255.12592220000002)
(2z)-1-[(1r,5s)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-3-phenylprop-2-en-1-one
(6z,8e)-2,5-dihydroxy-n-(2-methylpropyl)deca-6,8-dienimidic acid
(2r,3r,4r,5r)-2-(3-hydroxy-4-methoxyphenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol
C12H17NO5 (255.11066720000002)
n-(2-methylpropyl)trideca-2,6,8-trien-10,12-diynimidic acid
(2e,6z,8r,9r)-8,9-dihydroxy-n-(2-methylpropyl)deca-2,6-dienimidic acid
n-(1-hydroxy-3-phenylpropan-2-yl)benzenecarboximidic acid
C16H17NO2 (255.12592220000002)
(5z,8z)-11,12-dihydroxytetradeca-5,8-dienimidic acid
(1,7-dihydroxy-hexahydropyrrolizin-1-yl)methyl 2-methylbut-2-enoate
(1s,3r,5r,6r,7r)-3,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl 2-methylbut-2-enoate
(3e,5e)-1-[(2r)-1-methylpyrrolidin-2-yl]-6-phenylhexa-3,5-dien-2-one
4-methoxy-1-methyl-3-(3-methylbuta-1,3-dien-1-yl)quinolin-2-one
C16H17NO2 (255.12592220000002)
(1r,3r,5s,6s,7s)-3,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl (2e)-2-methylbut-2-enoate
2-[(2e)-hept-2-en-1-yl]-3-methyl-1h-quinolin-4-one
(2e,7e)-6,9-dihydroxy-n-(2-methylpropyl)deca-2,7-dienimidic acid
(1s,3r,5r,6r,7r)-3,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl (2z)-2-methylbut-2-enoate
(1s,4s)-4,5-dihydroxy-1-methyl-7-(2-methylpropyl)-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one
C12H17NO5 (255.11066720000002)
6,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2e)-2-methylbut-2-enoate
methyl 2-{[ethoxy(hydroxy)methylidene]amino}-3-(1-methylimidazol-4-yl)propanoate
[(1r,2r,7r,7ar)-2,7-dihydroxy-hexahydro-1h-pyrrolizin-1-yl]methyl (2z)-2-methylbut-2-enoate
(1s,7ar)-7-(chloromethyl)-2,3,5,7a-tetrahydro-1h-pyrrolizin-1-yl (2z)-2-methylbut-2-enoate
(1r,3r,5s,6r,7r)-6,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2e)-2-methylbut-2-enoate
(2e,6e,8z)-n-(2-methylpropyl)trideca-2,6,8-trien-10,12-diynimidic acid
(6r,9r)-6,9-dihydroxy-n-(2-methylpropyl)deca-2,7-dienimidic acid
(1r,3r,5s,6s,7r)-3,7-dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl (2e)-2-methylbut-2-enoate
1-(4-hydroxy-2-imino-7,8-dihydro-1h-pteridin-6-yl)propane-1,2,3-triol
(3s,4s,4ar,8r)-4-ethenyl-3-ethoxy-8-methoxy-3h,4h,4ah,5h,6h,7h-pyrano[3,4-c]pyridin-8-ol
1-[(3r,4s,5s)-2,3,4-trihydroxy-5-methyl-4,5-dihydropyrrol-3-yl]oct-4-en-1-one
n-[2-(3-methylimidazol-4-yl)ethyl]-3-phenylprop-2-enimidic acid
(2e,6z)-8,9-dihydroxy-n-(2-methylpropyl)deca-2,6-dienimidic acid
3,4-dimethoxy-1,2-dimethyl-9h-carbazole
C16H17NO2 (255.12592220000002)