11-Oxo etiocholanolone (BioDeep_00001875263)

Main id: BioDeep_00000002625

 


代谢物信息卡片


3alpha-hydroxy-5beta-androstane-11,17-dione

化学式: C19H28O3 (304.2038338)
中文名称: 11-氧噻吩乙醇酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC12CCC(CC1CCC3C2C(=O)CC4(C3CCC4=O)C)O
InChI: InChI=1S/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h11-14,17,20H,3-10H2,1-2H3/t11-,12-,13+,14+,17-,18+,19+/m1/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones

同义名列表

3 个代谢物同义名

3alpha-hydroxy-5beta-androstane-11,17-dione; 11-Oxo etiocholanolone; 11-Ketoetiocholanolone



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Micaela B Ruiz, Gabina V Eguizábal, Daniel P Villarreal, Juan M Busso, Abel G López. Inhibitory action of thymol on fecal microbial activity in Tamandua tetradactyla and its effect on glucocorticoid metabolite measurement. General and comparative endocrinology. 2019 09; 280(?):91-96. doi: 10.1016/j.ygcen.2019.04.015. [PMID: 31002827]
  • Xavier de la Torre, Daniel Jardines, Davide Curcio, Cristiana Colamonici, Francesco Botrè. Isotope ratio mass spectrometry in antidoping analysis: The use of endogenous reference compounds. Rapid communications in mass spectrometry : RCM. 2019 Mar; 33(6):579-586. doi: 10.1002/rcm.8377. [PMID: 30589473]
  • Peter N Laver, André Ganswindt, Stefanie B Ganswindt, Kathleen A Alexander. Non-invasive monitoring of glucocorticoid metabolites in banded mongooses (Mungos mungo) in response to physiological and biological challenges. General and comparative endocrinology. 2012 Nov; 179(2):178-83. doi: 10.1016/j.ygcen.2012.08.011. [PMID: 22926328]
  • André Ganswindt, Charlotte Muilwijk, Monique Engelkes, Stefanie Muenscher, Henk Bertschinger, Monique Paris, Rupert Palme, Elissa Z Cameron, Nigel C Bennett, Fredrik Dalerum. Validation of noninvasive monitoring of adrenocortical endocrine activity in ground-feeding aardwolves (Proteles cristata): exemplifying the influence of consumption of inorganic material for fecal steroid analysis. Physiological and biochemical zoology : PBZ. 2012 Mar; 85(2):194-9. doi: 10.1086/664591. [PMID: 22418711]
  • Herbert J Tobias, Ying Zhang, Richard J Auchus, J Thomas Brenna. Detection of synthetic testosterone use by novel comprehensive two-dimensional gas chromatography combustion-isotope ratio mass spectrometry. Analytical chemistry. 2011 Sep; 83(18):7158-65. doi: 10.1021/ac2015849. [PMID: 21846122]
  • Man Ho Choi, Ju-Yeon Moon, Sung-Hee Cho, Bong Chul Chung, Eun Jig Lee. Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma. BMC cancer. 2011 Aug; 11(?):342. doi: 10.1186/1471-2407-11-342. [PMID: 21824401]
  • Yogesh Kumar Katare, Alexander P Scott, Alyson J Laframboise, Weiming Li, Zena Alyasha'e, Christopher B Caputo, Stephen J Loeb, Barbara Zielinski. Release of free and conjugated forms of the putative pheromonal steroid 11-oxo-etiocholanolone by reproductively mature male round goby (Neogobius melanostomus Pallas, 1814). Biology of reproduction. 2011 Feb; 84(2):288-98. doi: 10.1095/biolreprod.110.086546. [PMID: 20944082]
  • Marie-Odile M Chelini, Emma Otta, Clarissa Yamakita, Rupert Palme. Sex differences in the excretion of fecal glucocorticoid metabolites in the Syrian hamster. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 2010 Aug; 180(6):919-25. doi: 10.1007/s00360-010-0467-9. [PMID: 20336462]
  • Birgit Flauger, Konstanze Krueger, Hartmut Gerhards, Erich Möstl. Simplified method to measure glucocorticoid metabolites in faeces of horses. Veterinary research communications. 2010 Feb; 34(2):185-95. doi: 10.1007/s11259-010-9344-y. [PMID: 20182914]
  • Monica Mazzarino, Maria Cristina Braganò, Francesco Donati, Xavier de la Torre, Francesco Botrè. Effects of propyphenazone and other non-steroidal anti-inflammatory agents on the synthetic and endogenous androgenic anabolic steroids urinary excretion and/or instrumental detection. Analytica chimica acta. 2010 Jan; 657(1):60-8. doi: 10.1016/j.aca.2009.10.022. [PMID: 19951758]
  • Lance Brooker, Maria Kristina Parr, Adam Cawley, Ulrich Flenker, Christopher Howe, Rymantas Kazlauskas, Wilhelm Schänzer, Adrian George. Development of criteria for the detection of adrenosterone administration by gas chromatography-mass spectrometry and gas chromatography-combustion-isotope ratio mass spectrometry for doping control. Drug testing and analysis. 2009 Nov; 1(11-12):587-95. doi: 10.1002/dta.108. [PMID: 20355175]
  • Noura Meklat, Jean-Claude Tabet, Jacques de Ceaurriz. Urine ratio of tetrahydrocortisol to tetrahydrodeoxycortisol to screen for the systemic administration of cortisone and hydrocortisone. Forensic science international. 2009 Mar; 185(1-3):e13-7. doi: 10.1016/j.forsciint.2008.12.011. [PMID: 19185436]
  • Jeremy W Tomlinson, Joanne Finney, Christopher Gay, Beverly A Hughes, Susan V Hughes, Paul M Stewart. Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity. Diabetes. 2008 Oct; 57(10):2652-60. doi: 10.2337/db08-0495. [PMID: 18633104]
  • M Nováková, R Palme, H Kutalová, L Janský, D Frynta. The effects of sex, age and commensal way of life on levels of fecal glucocorticoid metabolites in spiny mice (Acomys cahirinus). Physiology & behavior. 2008 Sep; 95(1-2):187-93. doi: 10.1016/j.physbeh.2008.05.017. [PMID: 18586285]
  • Hanspeter W Steinmetz, Werner Kaumanns, Illona Dix, Michael Heistermann, Mark Fox, Franz-Josef Kaup. Coat condition, housing condition and measurement of faecal cortisol metabolites--a non-invasive study about alopecia in captive rhesus macaques (Macaca mulatta). Journal of medical primatology. 2006 Feb; 35(1):3-11. doi: 10.1111/j.1600-0684.2005.00141.x. [PMID: 16430489]
  • B H Jung, S W Bai, B C Chung. Endogenous urinary steroids in premenopausal women with uterine leiomyomas. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 2004 Jan; 84(1):55-60. doi: 10.1016/s0020-7292(03)00336-9. [PMID: 14698830]
  • N I Bahr, R Palme, U Möhle, J K Hodges, M Heistermann. Comparative aspects of the metabolism and excretion of cortisol in three individual nonhuman primates. General and comparative endocrinology. 2000 Mar; 117(3):427-38. doi: 10.1006/gcen.1999.7431. [PMID: 10764553]
  • W Goymann, E Möstl, T Van't Hof, M L East, H Hofer. Noninvasive fecal monitoring of glucocorticoids in spotted hyenas, Crocuta crocuta. General and comparative endocrinology. 1999 Jun; 114(3):340-8. doi: 10.1006/gcen.1999.7268. [PMID: 10336822]
  • B Wallner, E Möstl, J Dittami, H Prossinger. Fecal glucocorticoids document stress in female Barbary macaques (Macaca sylvanus). General and comparative endocrinology. 1999 Jan; 113(1):80-6. doi: 10.1006/gcen.1998.7183. [PMID: 9882546]
  • H V Henning, H Ludwig-Köhn. Neutral steroid metabolites in body fluids of patients with uremia and after renal transplantation. Contributions to nephrology. 1986; 50(?):153-66. doi: 10.1159/000412996. [PMID: 3542370]
  • F Roelfsema, A J Moolenaar, M Frölich. The influence of bromocriptine and transsphenoidal surgery on urinary androgen metabolite excretion in acromegaly. Acta endocrinologica. 1984 Nov; 107(3):302-11. doi: 10.1530/acta.0.1070302. [PMID: 6095571]
  • L Gregolini, S Ferrari, R Marcolongo, M F Aleo, E Marinello, E Bianchi. Hormonal aspects of human gout--excretion of adrenal hormone derivatives in gouty patients. Clinica chimica acta; international journal of clinical chemistry. 1983 Jun; 130(3):269-77. doi: 10.1016/0009-8981(83)90300-5. [PMID: 6223725]
  • P S Pedersen, E W Flensborg, S G Johnsen. Urinary 17-ketosteroids in cystic fibrosis. Acta paediatrica Scandinavica. 1981 Jul; 70(4):507-12. doi: 10.1111/j.1651-2227.1981.tb05731.x. [PMID: 7315297]
  • R Gunasegaram. Effect of dexamethasone and ACTH on the secretion pattern of fractionated 17-ketosteroids in hirsutism. Annals of the Academy of Medicine, Singapore. 1979 Apr; 8(2):172-9. doi: . [PMID: 232832]
  • T P Moyer, P C Carpenter, N Jiang, D Machacek. Laboratory medicine. Series on clinical testing. 2. Fractionation of urinary ketosteroids. Procedure and clinical significance. Mayo Clinic proceedings. 1978 Sep; 53(9):601-6. doi: . [PMID: 150475]