methoxychlor (BioDeep_00000858367)
Main id: BioDeep_00000008459
Volatile Flavor Compounds
代谢物信息卡片
Benzene,1,1-(2,2,2-trichloroethylidene)bis[4-methoxy-
化学式: C16H15Cl3O2 (344.013758)
中文名称: 甲氧滴滴涕
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)C(Cl)(Cl)Cl
InChI: InChI=1S/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H3
描述信息
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:6842
- KEGG: C11043
- KEGGdrug: D91527
- PubChem: 4115
- ChEMBL: CHEMBL362919
- MeSH: Methoxychlor
- CAS: 1644449-82-0
- CAS: 72-43-5
- PubChem: 13226
- NIKKAJI: J2.377I
- KNApSAcK: 6842
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Patrycja Witek, Małgorzata Grzesiak, Marek Koziorowski, Maria Slomczynska, Katarzyna Knapczyk-Stwora. Long-Term Changes in Ovarian Follicles of Gilts Exposed Neonatally to Methoxychlor: Effects on Oocyte-Derived Factors, Anti-Müllerian Hormone, Follicle-Stimulating Hormone, and Cognate Receptors.
International journal of molecular sciences.
2022 Mar; 23(5):. doi:
10.3390/ijms23052780. [PMID: 35269923] - Hannes Reinwald, Julia Alvincz, Gabriela Salinas, Christoph Schäfers, Henner Hollert, Sebastian Eilebrecht. Toxicogenomic profiling after sublethal exposure to nerve- and muscle-targeting insecticides reveals cardiac and neuronal developmental effects in zebrafish embryos.
Chemosphere.
2022 Mar; 291(Pt 1):132746. doi:
10.1016/j.chemosphere.2021.132746. [PMID: 34748799] - Katarzyna Knapczyk-Stwora, Anna Nynca, Sylwia Swigonska, Lukasz Paukszto, Jan P Jastrzebski, Patrycja Witek, Marek Koziorowski, Maria Slomczynska. Effects of neonatal methoxychlor exposure on the ovarian transcriptome in piglets.
Animal reproduction science.
2022 Mar; 238(?):106956. doi:
10.1016/j.anireprosci.2022.106956. [PMID: 35231789] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Lin Cheng, Weiguo Song, Qinxiong Rao, Junliang Zhou, Zhihui Zhao. Bioaccumulation and toxicity of methoxychlor on Chinese mitten crab (Eriocheir sinensis).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2019 Jul; 221(?):89-95. doi:
10.1016/j.cbpc.2019.04.002. [PMID: 30954688] - Katarzyna Knapczyk-Stwora, Malgorzata Grzesiak, Renata E Ciereszko, Elzbieta Czaja, Marek Koziorowski, Maria Slomczynska. The impact of sex steroid agonists and antagonists on folliculogenesis in the neonatal porcine ovary via cell proliferation and apoptosis.
Theriogenology.
2018 Jun; 113(?):19-26. doi:
10.1016/j.theriogenology.2018.02.008. [PMID: 29452853] - Jitender Kumar Bhardwaj, Priyanka Saraf. N-acetyl cysteine-mediated effective attenuation of methoxychlor-induced granulosa cell apoptosis by counteracting reactive oxygen species generation in caprine ovary.
Environmental toxicology.
2017 Jan; 32(1):156-166. doi:
10.1002/tox.22221. [PMID: 26635070] - Yu Liu, Ya-Long Wang, Ming-Huang Chen, Zhen Zhang, Bai-Hui Xu, Rui Liu, Lin Xu, Shu-Wen He, Fei-Ping Li, Zhong-Quan Qi, Hai-Long Wang. Methoxychlor exposure induces oxidative stress and affects mouse oocyte meiotic maturation.
Molecular reproduction and development.
2016 09; 83(9):768-779. doi:
10.1002/mrd.22683. [PMID: 27434785] - Christopher J Martyniuk, Nicholas J Doperalski, April Feswick, Melinda S Prucha, Kevin J Kroll, David S Barber, Nancy D Denslow. Transcriptional networks associated with the immune system are disrupted by organochlorine pesticides in largemouth bass (Micropterus salmoides) ovary.
Aquatic toxicology (Amsterdam, Netherlands).
2016 Aug; 177(?):405-16. doi:
10.1016/j.aquatox.2016.06.009. [PMID: 27391359] - Stephen J Genuis, Kevin Lane, Detlef Birkholz. Human Elimination of Organochlorine Pesticides: Blood, Urine, and Sweat Study.
BioMed research international.
2016; 2016(?):1624643. doi:
10.1155/2016/1624643. [PMID: 27800487] - Huixiao Hong, William S Branham, Hui Wen Ng, Carrie L Moland, Stacey L Dial, Hong Fang, Roger Perkins, Daniel Sheehan, Weida Tong. Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.
Toxicological sciences : an official journal of the Society of Toxicology.
2015 Feb; 143(2):333-48. doi:
10.1093/toxsci/kfu231. [PMID: 25349334] - Eman E El-Sharkawy, Amany O G Kames, S M Sayed, Neveen A E L Nisr, Nahed M Wahba, Walaa M Elsherif, Allam M Nafady, M M Abdel-Hafeez, A A Aamer. The ameliorative effect of propolis against methoxychlor induced ovarian toxicity in rat.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2014 Dec; 66(9-10):415-21. doi:
10.1016/j.etp.2014.06.003. [PMID: 25034310] - Bingbing Chen, Dongxin Chen, Zheli Jiang, Jingyang Li, Shiwen Liu, Yaoyao Dong, Wenwen Yao, Benson Akingbemi, Renshan Ge, Xiaokun Li. Effects of estradiol and methoxychlor on Leydig cell regeneration in the adult rat testis.
International journal of molecular sciences.
2014 May; 15(5):7812-26. doi:
10.3390/ijms15057812. [PMID: 24806340] - Mohan Manikkam, M Muksitul Haque, Carlos Guerrero-Bosagna, Eric E Nilsson, Michael K Skinner. Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline.
PloS one.
2014; 9(7):e102091. doi:
10.1371/journal.pone.0102091. [PMID: 25057798] - Hamdy A A Aly, Ahmad S Azhar. Methoxychlor induced biochemical alterations and disruption of spermatogenesis in adult rats.
Reproductive toxicology (Elmsford, N.Y.).
2013 Sep; 40(?):8-15. doi:
10.1016/j.reprotox.2013.05.002. [PMID: 23684758] - R Nishino, T Fukuyama, Y Tajima, L Miyashita, Y Watanabe, H Ueda, T Kosaka. Prior oral exposure to environmental immunosuppressive chemicals methoxychlor, parathion, or piperonyl butoxide aggravates allergic airway inflammation in NC/Nga mice.
Toxicology.
2013 Jul; 309(?):1-8. doi:
10.1016/j.tox.2013.03.018. [PMID: 23583882] - Koichi Hayashi, Tomoki Fukuyama, Aya Ohnuma, Yukari Tajima, Yukiko Kashimoto, Toshinori Yoshida, Tadashi Kosaka. Immunotoxicity of the organochlorine pesticide methoxychlor in female ICR, BALB/c, and C3H/He mice.
Journal of immunotoxicology.
2013 Apr; 10(2):119-24. doi:
10.3109/1547691x.2012.696743. [PMID: 22967064] - Jingjing Guo, Haiyun Deng, Hongzhi Li, Qiqi Zhu, Binghai Zhao, Bingbing Chen, Yanhui Chu, Ren-Shan Ge. Effects of methoxychlor and its metabolite 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 11β-hydroxysteroid dehydrogenase activities in vitro.
Toxicology letters.
2013 Mar; 218(1):18-23. doi:
10.1016/j.toxlet.2013.01.002. [PMID: 23333641] - He-Hsiung Cheng, Yi-Chau Lu, Ti Lu, Jin-Shiung Cheng, Guang-Yuan Mar, Yi-Chien Fang, Kuo-Liang Chai, Chung-Ren Jan. Effect of methoxychlor on Ca(2+) movement and viability in MDCK renal tubular cells.
Basic & clinical pharmacology & toxicology.
2012 Oct; 111(4):224-31. doi:
10.1111/j.1742-7843.2012.00887.x. [PMID: 22458924] - T Fukuyama, T Kosaka, L Miyashita, R Nishino, K Wada, K Hayashi, H Ueda, T Harada. Role of regulatory T cells in the induction of atopic dermatitis by immunosuppressive chemicals.
Toxicology letters.
2012 Sep; 213(3):392-401. doi:
10.1016/j.toxlet.2012.07.018. [PMID: 22842586] - Mohammad Abdur Rahman, Alamgir Zaman Chowdhury, Mohammed Moniruzzaman, Siew Hua Gan, Mohammad Nazrul Islam, Zeenath Fardous, Mohammad Khorshed Alam. Pesticide residues in tobacco leaves from the Kushtia district in Bangladesh.
Bulletin of environmental contamination and toxicology.
2012 Sep; 89(3):658-63. doi:
10.1007/s00128-012-0725-5. [PMID: 22782359] - Carmen Freire, Rosalina Jorge Koifman, Paula Sarcinelli, Ana Cristina Rosa, Ruth Clapauch, Sergio Koifman. Long term exposure to organochlorine pesticides and thyroid function in children from Cidade dos Meninos, Rio de Janeiro, Brazil.
Environmental research.
2012 Aug; 117(?):68-74. doi:
10.1016/j.envres.2012.06.009. [PMID: 22776325] - Samim Ozen, Sukran Darcan, Petek Bayindir, Ercument Karasulu, Damla Goksen Simsek, Tahir Gurler. Effects of pesticides used in agriculture on the development of precocious puberty.
Environmental monitoring and assessment.
2012 Jul; 184(7):4223-32. doi:
10.1007/s10661-011-2257-6. [PMID: 21805074] - Agung Dhamar Syakti, Laurence Asia, Fehmi Kanzari, Halikkudin Umasangadji, Laure Malleret, Yann Ternois, Gilbert Mille, Pierre Doumenq. Distribution of organochlorine pesticides (OCs) and polychlorinated biphenyls (PCBs) in marine sediments directly exposed to wastewater from Cortiou, Marseille.
Environmental science and pollution research international.
2012 Jun; 19(5):1524-35. doi:
10.1007/s11356-011-0640-z. [PMID: 22051976] - Serpil Yenisoy-Karakaş, Muhammed Öz, Eftade O Gaga. Seasonal variation, sources, and gas/particle concentrations of PCBs and OCPs at high altitude suburban site in Western Black Sea Region of Turkey.
Journal of environmental monitoring : JEM.
2012 May; 14(5):1365-74. doi:
10.1039/c2em30038a. [PMID: 22441172] - Shruthi Mahalingaiah, Stacey A Missmer, Arnab Maity, Paige L Williams, John D Meeker, Katharine Berry, Shelley Ehrlich, Melissa J Perry, Daniel W Cramer, Russ Hauser. Association of hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) with in vitro fertilization (IVF) outcomes.
Environmental health perspectives.
2012 Feb; 120(2):316-20. doi:
10.1289/ehp.1103696. [PMID: 22204795] - C A Frye, E Bo, G Calamandrei, L Calzà, F Dessì-Fulgheri, M Fernández, L Fusani, O Kah, M Kajta, Y Le Page, H B Patisaul, A Venerosi, A K Wojtowicz, G C Panzica. Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems.
Journal of neuroendocrinology.
2012 Jan; 24(1):144-59. doi:
10.1111/j.1365-2826.2011.02229.x. [PMID: 21951193] - Christiaan J Malherbe, Dalene De Beer, Elizabeth Joubert. Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.
International journal of molecular sciences.
2012; 13(3):3101-3133. doi:
10.3390/ijms13033101. [PMID: 22489144] - T Fukuyama, Y Tajima, K Hayashi, H Ueda, T Kosaka. Prior or coinstantaneous oral exposure to environmental immunosuppressive agents aggravates mite allergen-induced atopic dermatitis-like immunoreaction in NC/Nga mice.
Toxicology.
2011 Nov; 289(2-3):132-40. doi:
10.1016/j.tox.2011.08.003. [PMID: 21864637] - Beate I Escher, Christina E Cowan-Ellsberry, Scott Dyer, Michelle R Embry, Susan Erhardt, Marlies Halder, Jung-Hwan Kwon, Karla Johanning, Mattheus T T Oosterwijk, Sibylle Rutishauser, Helmut Segner, John Nichols. Protein and lipid binding parameters in rainbow trout (Oncorhynchus mykiss) blood and liver fractions to extrapolate from an in vitro metabolic degradation assay to in vivo bioaccumulation potential of hydrophobic organic chemicals.
Chemical research in toxicology.
2011 Jul; 24(7):1134-43. doi:
10.1021/tx200114y. [PMID: 21604782] - Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.
Toxicology.
2011 Feb; 280(3):77-87. doi:
10.1016/j.tox.2010.11.008. [PMID: 21115097] - George W Yu, John Laseter, Charles Mylander. Persistent organic pollutants in serum and several different fat compartments in humans.
Journal of environmental and public health.
2011; 2011(?):417980. doi:
10.1155/2011/417980. [PMID: 21647350] - Antonia M Calafat, Lee-Yang Wong, Manori J Silva, Ella Samandar, James L Preau, Lily T Jia, Larry L Needham. Selecting adequate exposure biomarkers of diisononyl and diisodecyl phthalates: data from the 2005-2006 National Health and Nutrition Examination Survey.
Environmental health perspectives.
2011 Jan; 119(1):50-5. doi:
10.1289/ehp.1002316. [PMID: 20870567] - Laura Canesi, Alessandro Negri, Cristina Barmo, Mohamed Banni, Gabriella Gallo, Aldo Viarengo, Francesco Dondero. The organophosphate Chlorpyrifos interferes with the responses to 17β-estradiol in the digestive gland of the marine mussel Mytilus galloprovincialis.
PloS one.
2011; 6(5):e19803. doi:
10.1371/journal.pone.0019803. [PMID: 21625485] - Alexander P Sobinoff, Victoria Pye, Brett Nixon, Shaun D Roman, Eileen A McLaughlin. Adding insult to injury: effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility.
Toxicological sciences : an official journal of the Society of Toxicology.
2010 Dec; 118(2):653-66. doi:
10.1093/toxsci/kfq272. [PMID: 20829426] - David Cantonwine, John D Meeker, Howard Hu, Brisa N Sánchez, Héctor Lamadrid-Figueroa, Adriana Mercado-García, Gamola Z Fortenberry, Antonia M Calafat, Martha Maria Téllez-Rojo. Bisphenol a exposure in Mexico City and risk of prematurity: a pilot nested case control study.
Environmental health : a global access science source.
2010 Oct; 9(?):62. doi:
10.1186/1476-069x-9-62. [PMID: 20955576] - K K Grewal, G S Sandhu, Ranjit Kaur, R S Brar, H S Sandhu. Toxic impacts of cypermethrin on behavior and histology of certain tissues of albino rats.
Toxicology international.
2010 Jul; 17(2):94-8. doi:
10.4103/0971-6580.72679. [PMID: 21170254] - T Lóránd, E Vigh, J Garai. Hormonal action of plant derived and anthropogenic non-steroidal estrogenic compounds: phytoestrogens and xenoestrogens.
Current medicinal chemistry.
2010; 17(30):3542-74. doi:
10.2174/092986710792927813. [PMID: 20738246] - I Windal, V Hanot, J Marchi, G Huysmans, I Van Overmeire, N Waegeneers, L Goeyens. PCB and organochlorine pesticides in home-produced eggs in Belgium.
The Science of the total environment.
2009 Jul; 407(15):4430-7. doi:
10.1016/j.scitotenv.2008.11.063. [PMID: 19150570] - John D Meeker, Stacey A Missmer, Larisa Altshul, Allison F Vitonis, Louise Ryan, Daniel W Cramer, Russ Hauser. Serum and follicular fluid organochlorine concentrations among women undergoing assisted reproduction technologies.
Environmental health : a global access science source.
2009 Jul; 8(?):32. doi:
10.1186/1476-069x-8-32. [PMID: 19594949] - Ilaria Ceccarelli, Paolo Fiorenzani, Daniele Della Seta, Cosimo Massafra, Giuliano Cinci, Anna Bocci, Anna Maria Aloisi. Perinatal exposure to xenoestrogens affects pain in adult female rats.
Neurotoxicology and teratology.
2009 Jul; 31(4):203-9. doi:
10.1016/j.ntt.2009.02.004. [PMID: 19264124] - Chang-Hwan Oh. Monitoring of residual pesticides in herbal drug materials of Korea and China.
Bulletin of environmental contamination and toxicology.
2009 May; 82(5):639-43. doi:
10.1007/s00128-009-9649-0. [PMID: 19152059] - Katalin Prokai-Tatrai, Laszlo Prokai, James W Simpkins, Marianna E Jung. Phenolic compounds protect cultured hippocampal neurons against ethanol-withdrawal induced oxidative stress.
International journal of molecular sciences.
2009 Apr; 10(4):1773-1787. doi:
10.3390/ijms10041773. [PMID: 19468338] - Andrea N Edginton, Len Ritter. Predicting plasma concentrations of bisphenol A in children younger than 2 years of age after typical feeding schedules, using a physiologically based toxicokinetic model.
Environmental health perspectives.
2009 Apr; 117(4):645-52. doi:
10.1289/ehp.0800073. [PMID: 19440506] - Beatrice A Nyagode, Margaret O James, Kevin M Kleinow. Influence of dietary Coexposure to benzo(a)pyrene on the biotransformation and distribution of 14C-methoxychlor in the channel catfish (Ictalurus punctatus).
Toxicological sciences : an official journal of the Society of Toxicology.
2009 Apr; 108(2):320-9. doi:
10.1093/toxsci/kfp018. [PMID: 19181613] - S Vaithinathan, B Saradha, P P Mathur. Methoxychlor-induced alteration in the levels of HSP70 and clusterin is accompanied with oxidative stress in adult rat testis.
Journal of biochemical and molecular toxicology.
2009 Jan; 23(1):29-35. doi:
10.1002/jbt.20262. [PMID: 19202561] - R Zamir, M Athanasiadou, N Nahar, M I R Mamun, M Mosihuzzaman, A Bergman. Persistent organohalogen contaminants in plasma from groups of humans with different occupations in Bangladesh.
Chemosphere.
2009 Jan; 74(3):453-9. doi:
10.1016/j.chemosphere.2008.09.043. [PMID: 18996566] - Kyu-Bong Kim, Seon Hwa Kim, So Young Um, Myeon Woo Chung, Ji Seon Oh, Seung-Chul Jung, Tae Sung Kim, Hyun Joo Moon, Soon Young Han, Hye Young Oh, Byung Mu Lee, Ki Hwan Choi. Metabolomics approach to risk assessment: methoxyclor exposure in rats.
Journal of toxicology and environmental health. Part A.
2009; 72(21-22):1352-68. doi:
10.1080/15287390903212550. [PMID: 20077207] - Changcheng Zhou, Suman Verma, Bruce Blumberg. The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.
Nuclear receptor signaling.
2009; 7(?):e001. doi:
10.1621/nrs.07001. [PMID: 19240808] - AnnMarie E Armenti, Aparna Mahakali Zama, Lisa Passantino, Mehmet Uzumcu. Developmental methoxychlor exposure affects multiple reproductive parameters and ovarian folliculogenesis and gene expression in adult rats.
Toxicology and applied pharmacology.
2008 Dec; 233(2):286-96. doi:
10.1016/j.taap.2008.09.010. [PMID: 18848953] - Jennifer A Rusiecki, Andrea Baccarelli, Valentina Bollati, Letizia Tarantini, Lee E Moore, Eva C Bonefeld-Jorgensen. Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit.
Environmental health perspectives.
2008 Nov; 116(11):1547-52. doi:
10.1289/ehp.11338. [PMID: 19057709] - Carlos M Guerrero-Bosagna, Pablo Sabat, Fernanda S Valdovinos, Luis E Valladares, Susan J Clark. Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice.
BMC physiology.
2008 Sep; 8(?):17. doi:
10.1186/1472-6793-8-17. [PMID: 18793434] - Mary S Wolff, Stephanie M Engel, Gertrud S Berkowitz, Xiaoyun Ye, Manori J Silva, Chenbo Zhu, James Wetmur, Antonia M Calafat. Prenatal phenol and phthalate exposures and birth outcomes.
Environmental health perspectives.
2008 Aug; 116(8):1092-7. doi:
10.1289/ehp.11007. [PMID: 18709157] - Kimberly A Salinas, Michael J Hemmer, Peggy S Harris, Calvin C Walker. A simple and rapid matrix-assisted laser desorption/ionization time of flight mass spectrometry method to screen fish plasma samples for estrogen-responsive biomarkers.
Environmental toxicology and chemistry.
2008 May; 27(5):1175-83. doi:
10.1897/07-226.1. [PMID: 18419181] - A Lafuente, T Cabaleiro, A Caride, A I Esquifino. Toxic effects of methoxychlor administered subcutaneously on the hypothalamic-pituitary-testicular axis in adult rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 May; 46(5):1570-5. doi:
10.1016/j.fct.2007.12.017. [PMID: 18226848] - Grégory Rasier, Anne-Simone Parent, Arlette Gérard, Raphaël Denooz, Marie-Christine Lebrethon, Corinne Charlier, Jean-Pierre Bourguignon. Mechanisms of interaction of endocrine-disrupting chemicals with glutamate-evoked secretion of gonadotropin-releasing hormone.
Toxicological sciences : an official journal of the Society of Toxicology.
2008 Mar; 102(1):33-41. doi:
10.1093/toxsci/kfm285. [PMID: 18032409] - Yucel Akgul, Raymond C Derk, Terence Meighan, K Murali Krishna Rao, Eisuke P Murono. The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells.
Reproductive toxicology (Elmsford, N.Y.).
2008 Jan; 25(1):67-75. doi:
10.1016/j.reprotox.2007.10.007. [PMID: 18065196] - Elisabete Silva, Martin Scholze, Andreas Kortenkamp. Activity of xenoestrogens at nanomolar concentrations in the E-Screen assay.
Environmental health perspectives.
2007 Dec; 115 Suppl 1(?):91-7. doi:
10.1289/ehp.9363. [PMID: 18174956] - J A van Meeuwen, W Ter Burg, A H Piersma, M van den Berg, J T Sanderson. Mixture effects of estrogenic compounds on proliferation and pS2 expression of MCF-7 human breast cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2007 Nov; 45(11):2319-30. doi:
10.1016/j.fct.2007.06.011. [PMID: 17651883] - M-J Lopez-Espinosa, A Granada, J Carreno, M Salvatierra, F Olea-Serrano, N Olea. Organochlorine pesticides in placentas from Southern Spain and some related factors.
Placenta.
2007 Jul; 28(7):631-8. doi:
10.1016/j.placenta.2006.09.009. [PMID: 17109956] - J A van Meeuwen, M van den Berg, J T Sanderson, A Verhoef, A H Piersma. Estrogenic effects of mixtures of phyto- and synthetic chemicals on uterine growth of prepubertal rats.
Toxicology letters.
2007 Apr; 170(2):165-76. doi:
10.1016/j.toxlet.2007.03.003. [PMID: 17428625] - Heqing Shen, Katharina M Main, Helena E Virtanen, Ida N Damggard, Anne-Maarit Haavisto, M Kaleva, K A Boisen, Ida M Schmidt, Marla Chellakooty, Niels E Skakkebaek, Jorma Toppari, Karl-Werner Schramm. From mother to child: investigation of prenatal and postnatal exposure to persistent bioaccumulating toxicants using breast milk and placenta biomonitoring.
Chemosphere.
2007 Apr; 67(9):S256-62. doi:
10.1016/j.chemosphere.2006.05.106. [PMID: 17207515] - Javier Carreño, Ana Rivas, Alicia Granada, Maria Jose Lopez-Espinosa, Miguel Mariscal, Nicolas Olea, Fatima Olea-Serrano. Exposure of young men to organochlorine pesticides in Southern Spain.
Environmental research.
2007 Jan; 103(1):55-61. doi:
10.1016/j.envres.2006.06.007. [PMID: 16889768] - Calvin C Walker, Kimberly A Salinas, Peggy S Harris, Sherry S Wilkinson, James D Watts, Michael J Hemmer. A proteomic (SELDI-TOF-MS) approach to estrogen agonist screening.
Toxicological sciences : an official journal of the Society of Toxicology.
2007 Jan; 95(1):74-81. doi:
10.1093/toxsci/kfl079. [PMID: 16917070] - Peter Thomas, Jing Dong. Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption.
The Journal of steroid biochemistry and molecular biology.
2006 Dec; 102(1-5):175-9. doi:
10.1016/j.jsbmb.2006.09.017. [PMID: 17088055] - Deliang Tang, Tin-yu Li, Jason J Liu, Yu-hui Chen, Lirong Qu, Frederica Perera. PAH-DNA adducts in cord blood and fetal and child development in a Chinese cohort.
Environmental health perspectives.
2006 Aug; 114(8):1297-300. doi:
10.1289/ehp.8939. [PMID: 16882543] - Ida N Damgaard, Niels E Skakkebaek, Jorma Toppari, Helena E Virtanen, Heqing Shen, Karl-Werner Schramm, Jørgen H Petersen, Tina K Jensen, Katharina M Main. Persistent pesticides in human breast milk and cryptorchidism.
Environmental health perspectives.
2006 Jul; 114(7):1133-8. doi:
10.1289/ehp.8741. [PMID: 16835070] - Helle Raun Andersen, Eva C Bonefeld-Jørgensen, Flemming Nielsen, Kirsten Jarfeldt, Magdalena Niepsuj Jayatissa, Anne Marie Vinggaard. Estrogenic effects in vitro and in vivo of the fungicide fenarimol.
Toxicology letters.
2006 May; 163(2):142-52. doi:
10.1016/j.toxlet.2005.10.004. [PMID: 16324804] - Suman Patel, Virendra Singh, Abhai Kumar, Yogendra Kumar Gupta, Mahendra Pratap Singh. Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration.
Brain research.
2006 Apr; 1081(1):9-18. doi:
10.1016/j.brainres.2006.01.060. [PMID: 16510128] - Tyrone B Hayes, Paola Case, Sarah Chui, Duc Chung, Cathryn Haeffele, Kelly Haston, Melissa Lee, Vien Phoung Mai, Youssra Marjuoa, John Parker, Mable Tsui. Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?.
Environmental health perspectives.
2006 Apr; 114 Suppl 1(?):40-50. doi:
10.1289/ehp.8051. [PMID: 16818245] - Thomas H Hutchinson, Gerald T Ankley, Helmut Segner, Charles R Tyler. Screening and testing for endocrine disruption in fish-biomarkers as 'signposts,' not 'traffic lights,' in risk assessment.
Environmental health perspectives.
2006 Apr; 114 Suppl 1(?):106-14. doi:
10.1289/ehp.8062. [PMID: 16818255] - Anunciación Lafuente, Teresa Cabaleiro, Pilar Cano, Ana I Esquifino. Toxic effects of methoxychlor on the episodic prolactin secretory pattern: possible mediated effects of nitric oxide production.
Journal of circadian rhythms.
2006 Mar; 4(?):3. doi:
10.1186/1740-3391-4-3. [PMID: 16515688] - Kuladip Jana, Subarna Jana, Prabhat Kumar Samanta. Effects of chronic exposure to sodium arsenite on hypothalamo-pituitary-testicular activities in adult rats: possible an estrogenic mode of action.
Reproductive biology and endocrinology : RB&E.
2006 Feb; 4(?):9. doi:
10.1186/1477-7827-4-9. [PMID: 16483355] - Eisuke P Murono, Raymond C Derk, Yucel Akgul. In vivo exposure of young adult male rats to methoxychlor reduces serum testosterone levels and ex vivo Leydig cell testosterone formation and cholesterol side-chain cleavage activity.
Reproductive toxicology (Elmsford, N.Y.).
2006 Feb; 21(2):148-53. doi:
10.1016/j.reprotox.2005.08.005. [PMID: 16226009] - G A Stern, C R Macdonald, D Armstrong, B Dunn, C Fuchs, L Harwood, D C G Muir, B Rosenberg. Spatial trends and factors affecting variation of organochlorine contaminants levels in Canadian Arctic beluga (Delphinapterus leucas).
The Science of the total environment.
2005 Dec; 351-352(?):344-68. doi:
10.1016/j.scitotenv.2004.10.033. [PMID: 16154619] - Pierre Ayotte, Eric Dewailly, George H Lambert, Sherry L Perkins, Raymond Poon, Mark Feeley, Christian Larochelle, Daria Pereg. Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines.
Environmental health perspectives.
2005 Oct; 113(10):1318-24. doi:
10.1289/ehp.7970. [PMID: 16203240] - M A Ottinger, M J Quinn, E Lavoie, M A Abdelnabi, N Thompson, J L Hazelton, J M Wu, J Beavers, M Jaber. Consequences of endocrine disrupting chemicals on reproductive endocrine function in birds: establishing reliable end points of exposure.
Domestic animal endocrinology.
2005 Aug; 29(2):411-9. doi:
10.1016/j.domaniend.2005.02.038. [PMID: 15998506] - Ana C Ruiz-Luna, Stephanie Salazar, Norma J Aspajo, Julio Rubio, Manuel Gasco, Gustavo F Gonzales. Lepidium meyenii (Maca) increases litter size in normal adult female mice.
Reproductive biology and endocrinology : RB&E.
2005 May; 3(?):16. doi:
10.1186/1477-7827-3-16. [PMID: 15869705] - Mary Ann Ottinger, Julie M Wu, Julie L Hazelton, Mahmoud A Abdelnabi, Nichola Thompson, Michael L Quinn, Dan Donoghue, Frank Schenck, Michael Ruscio, Joanne Beavers, Mark Jaber. Assessing the consequences of the pesticide methoxychlor: neuroendocrine and behavioral measures as indicators of biological impact of an estrogenic environmental chemical.
Brain research bulletin.
2005 Apr; 65(3):199-209. doi:
10.1016/j.brainresbull.2004.11.019. [PMID: 15811582] - Antonia M Calafat, Zsuzsanna Kuklenyik, John A Reidy, Samuel P Caudill, John Ekong, Larry L Needham. Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population.
Environmental health perspectives.
2005 Apr; 113(4):391-5. doi:
10.1289/ehp.7534. [PMID: 15811827] - Eric S Sobel, John Gianini, Edward J Butfiloski, Byron P Croker, Joel Schiffenbauer, Stephen M Roberts. Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice.
Environmental health perspectives.
2005 Mar; 113(3):323-8. doi:
10.1289/ehp.7347. [PMID: 15743722] - Hideki Fukata, Mariko Omori, Hisao Osada, Emiko Todaka, Chisato Mori. Necessity to measure PCBs and organochlorine pesticide concentrations in human umbilical cords for fetal exposure assessment.
Environmental health perspectives.
2005 Mar; 113(3):297-303. doi:
10.1289/ehp.7330. [PMID: 15743718] - Thomas R Rainwater, Kevin D Reynolds, Jaclyn E Cañas, George P Cobb, Todd A Anderson, Scott T McMurry, Philip N Smith. Organochlorine pesticides and mercury in cottonmouths (Agkistrodon piscivorus) from northeastern Texas, USA.
Environmental toxicology and chemistry.
2005 Mar; 24(3):665-73. doi:
10.1897/04-223r.1. [PMID: 15779767] - Eszter Hazai, David Kupfer. Interactions between CYP2C9 and CYP2C19 in reconstituted binary systems influence their catalytic activity: possible rationale for the inability of CYP2C19 to catalyze methoxychlor demethylation in human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals.
2005 Jan; 33(1):157-64. doi:
10.1124/dmd.104.001578. [PMID: 15486075] - Mari S Golub, Casey E Hogrefe, Stacey L Germann, Christopher P Jerome. Endocrine disruption in adolescence: immunologic, hematologic, and bone effects in monkeys.
Toxicological sciences : an official journal of the Society of Toxicology.
2004 Dec; 82(2):598-607. doi:
10.1093/toxsci/kfh295. [PMID: 15456917] - Stéphane Bayen, Yinhan Gong, Hong Soon Chin, Hian Kee Lee, Yong Eu Leong, Jeffrey Philip Obbard. Androgenic and estrogenic response of green mussel extracts from Singapore's coastal environment using a human cell-based bioassay.
Environmental health perspectives.
2004 Nov; 112(15):1467-71. doi:
10.1289/ehp.6990. [PMID: 15531429] - Begoña Botella, Jorge Crespo, Ana Rivas, Isabel Cerrillo, Maria Fátima Olea-Serrano, Nicolás Olea. Exposure of women to organochlorine pesticides in Southern Spain.
Environmental research.
2004 Sep; 96(1):34-40. doi:
10.1016/j.envres.2003.10.001. [PMID: 15261782] - Masatoshi Suzuki, Hwi-Cheul Lee, Shuichi Chiba, Tomohiro Yonezawa, Masugi Nishihara. Effects of methoxychlor exposure during perinatal period on reproductive function after maturation in rats.
The Journal of reproduction and development.
2004 Aug; 50(4):455-61. doi:
10.1262/jrd.50.455. [PMID: 15329477] - Mercedes Moreno Frías, Margarita Jiménez Torres, Antonia Garrido Frenich, Jose Luis Martínez Vidal, Fátima Olea-Serrano, Nicolás Olea. Determination of organochlorine compounds in human biological samples by GC-MS/MS.
Biomedical chromatography : BMC.
2004 Mar; 18(2):102-11. doi:
10.1002/bmc.300. [PMID: 15039962] - Wilfried Karmaus, Xiaobei Zhu. Maternal concentration of polychlorinated biphenyls and dichlorodiphenyl dichlorethylene and birth weight in Michigan fish eaters: a cohort study.
Environmental health : a global access science source.
2004 Jan; 3(1):1. doi:
10.1186/1476-069x-3-1. [PMID: 14748928] - Li You. Phytoestrogen genistein and its pharmacological interactions with synthetic endocrine-active compounds.
Current pharmaceutical design.
2004; 10(22):2749-57. doi:
10.2174/1381612043383683. [PMID: 15320740] - David Bentrem, Jennifer E Fox, Sandra Timm Pearce, Hong Liu, Sam Pappas, David Kupfer, James W Zapf, V Craig Jordan. Distinct molecular conformations of the estrogen receptor alpha complex exploited by environmental estrogens.
Cancer research.
2003 Nov; 63(21):7490-6. doi:
". [PMID: 14612550] - Thomas Høj Rasmussen, Flemming Nielsen, Helle Raun Andersen, Jesper Bo Nielsen, Pal Weihe, Philippe Grandjean. Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts.
Environmental health : a global access science source.
2003 Oct; 2(1):12. doi:
10.1186/1476-069x-2-12. [PMID: 14613489] - Hong Fang, Weida Tong, William S Branham, Carrie L Moland, Stacy L Dial, Huixiao Hong, Qian Xie, Roger Perkins, William Owens, Daniel M Sheehan. Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
Chemical research in toxicology.
2003 Oct; 16(10):1338-58. doi:
10.1021/tx030011g. [PMID: 14565775] - Mari S Golub, Casey E Hogrefe, Stacey L Germann, Bill L Lasley, Kala Natarajan, Alice F Tarantal. Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys.
Toxicological sciences : an official journal of the Society of Toxicology.
2003 Jul; 74(1):103-13. doi:
10.1093/toxsci/kfg090. [PMID: 12730626] - Anunciación Lafuente, Aníbal González-Carracedo, Alejandro Romero, Ana I Esquifino. Methoxychlor modifies the ultradian secretory pattern of prolactin and affects its TRH response.
Medical science monitor : international medical journal of experimental and clinical research.
2003 May; 9(5):PI37-42. doi:
NULL. [PMID: 12761465] - Daniel B Pickford, Ian D Morris. Inhibition of gonadotropin-induced oviposition and ovarian steroidogenesis in the African clawed frog (Xenopus laevis) by the pesticide methoxychlor.
Aquatic toxicology (Amsterdam, Netherlands).
2003 Feb; 62(3):179-94. doi:
10.1016/s0166-445x(02)00082-6. [PMID: 12560167] - C Latchoumycandane, P P Mathur. Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor.
Archives of toxicology.
2002 Dec; 76(12):692-8. doi:
10.1007/s00204-002-0388-9. [PMID: 12451445]