Ethylketocyclazocine (BioDeep_00000008877)
Secondary id: BioDeep_00001870392
代谢物信息卡片
Ethylketocyclazocine
化学式: C19H25NO2 (299.1885)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(not specific) 50%
分子结构信息
SMILES: CCC12CCN(C(C1C)C(=O)C3=C2C=C(C=C3)O)CC4CC4
InChI: InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12?,17-,19+/m0/s1
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
同义名列表
5 个代谢物同义名
Ethylketocyclazocine; CHEMBL55033; CID 443409; EKC; Ethylketocyclazocine
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:4901
- KEGG: C11795
- PubChem: 443409
- Metlin: METLIN69225
- MeSH: Ethylketocyclazocine
- CAS: 36292-66-7
- PMhub: MS000022581
- PubChem: 13959
- NIKKAJI: J247.745I
- RefMet: Ethylketocyclazocine
- KNApSAcK: 4901
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Marilena Kampa, Evangelia A Papakonstanti, Vassilia-Ismini Alexaki, Anastassia Hatzoglou, Christos Stournaras, Elias Castanas. The opioid agonist ethylketocyclazocine reverts the rapid, non-genomic effects of membrane testosterone receptors in the human prostate LNCaP cell line.
Experimental cell research.
2004 Apr; 294(2):434-45. doi:
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Molecular biology of the cell.
2002 Aug; 13(8):2946-62. doi:
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The Journal of pharmacology and experimental therapeutics.
2001 Sep; 298(3):1049-59. doi:
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1999 Jul; 290(1):259-65. doi:
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Journal of cellular biochemistry.
1999 May; 73(2):204-11. doi:
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1995 May; 289(3):411-7. doi:
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Regional anesthesia.
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Neurochemical research.
1989 Mar; 14(3):205-10. doi:
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Pharmacology, biochemistry, and behavior.
1988 Aug; 30(4):967-75. doi:
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The American journal of physiology.
1988 Jun; 254(6 Pt 1):G802-7. doi:
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1988 Feb; 66(2):283-9. doi:
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Pharmacology.
1988; 37(6):356-64. doi:
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The Journal of pharmacology and experimental therapeutics.
1987 Aug; 242(2):421-7. doi:
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The Journal of pharmacology and experimental therapeutics.
1987 Jul; 242(1):33-9. doi:
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The Journal of pharmacology and experimental therapeutics.
1987 May; 241(2):534-9. doi:
. [PMID: 3033219] - E J Cone, D Yousefnejad, W D Buchwald, K Kumor. Determination of ketocyclazocine in human plasma by gas chromatography-negative-ion chemical-ionization mass spectrometry.
Journal of chromatography.
1986 Nov; 383(1):158-65. doi:
10.1016/s0378-4347(00)83455-6. [PMID: 3818834] - T P Blackburn, K R Borkowski, J Friend, M J Rance. On the mechanisms of kappa-opioid-induced diuresis.
British journal of pharmacology.
1986 Nov; 89(3):593-8. doi:
10.1111/j.1476-5381.1986.tb11160.x. [PMID: 3542107] - G R Slizgi, J H Ludens. Role of ADH in ethylketocyclazocine-induced diuresis: studies in the Brattleboro rat.
Life sciences.
1986 Jun; 38(26):2437-40. doi:
10.1016/0024-3205(86)90613-2. [PMID: 3014247] - E Castanas, N Bourhim, P Giraud, F Boudouresque, P Cantau, C Oliver. Interaction of opiates with opioid binding sites in the bovine adrenal medulla: II. Interaction with kappa sites.
Journal of neurochemistry.
1985 Sep; 45(3):688-99. doi:
10.1111/j.1471-4159.1985.tb04047.x. [PMID: 2993510] - G R Slizgi, J H Ludens. Displacement of 3H-EKC binding by opioids in rat kidney: a correlate to diuretic activity.
Life sciences.
1985 Jun; 36(23):2189-93. doi:
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1985 Jun; 233(3):863-9. doi:
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1985 Jan; 232(1):163-9. doi:
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European journal of pharmacology.
1984 Dec; 107(1):1-10. doi:
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Neuropeptides.
1984 Dec; 5(1-3):217-20. doi:
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Neuropeptides.
1984 Dec; 5(1-3):283-6. doi:
10.1016/0143-4179(84)90083-0. [PMID: 6099514] - H Ensinger, L Hedler, C Schurr, K Starke. Ethylketocyclazocine decreases noradrenaline release and blood pressure in the rabbit at a peripheral opioid receptor.
Naunyn-Schmiedeberg's archives of pharmacology.
1984 Nov; 328(1):20-3. doi:
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1984 Nov; 231(2):312-6. doi:
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The Journal of pharmacology and experimental therapeutics.
1983 Sep; 226(3):770-5. doi:
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The Journal of pharmacology and experimental therapeutics.
1983 Jan; 224(1):89-94. doi:
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Advances in shock research.
1983; 10(?):101-9. doi:
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