N-Acetyl-b-glucosaminylamine (BioDeep_00000003913)
Secondary id: BioDeep_00000419045
human metabolite Endogenous BioNovoGene_Lab2019
代谢物信息卡片
化学式: C8H16N2O5 (220.1059)
中文名称: 2-乙酰氨基-2-脱氧-b-d-葡萄糖胺, 2-乙酰氨基-2-脱氧-β-D-葡萄糖胺, 2-乙酰氨基-1-氨基-1,2-二脱氧-beta-D-吡喃葡萄糖
谱图信息:
最多检出来源 Homo sapiens(feces) 5.46%
分子结构信息
SMILES: CC(=O)NC1C(C(C(OC1N)CO)O)O
InChI: InChI=1S/C8H16N2O5/c1-3(12)10-5-7(14)6(13)4(2-11)15-8(5)9/h4-8,11,13-14H,2,9H2,1H3,(H,10,12)/t4-,5-,6-,7-,8-/m1/s1
描述信息
N-Acetyl-b-glucosaminylamine is the product of a reaction catalyzed vy the enzyme N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase [EC 3.5.1.26, Aspartylglucosaminidase, AGA]. AGA is a key enzyme in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves the asparagine from the residual N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Aspartylglucosaminuria (AGU) is a lysosomal disease caused by deficiency of N-aspartyl-beta-glucosaminidase. AGU is the only known lysosomal storage disease caused by an amidase deficiency. (OMIM208400).
同义名列表
10 个代谢物同义名
N-[(2R,3R,4R,5S,6R)-2-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide; N-[2-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide; 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYLAMINE; 2-Acetamido-2-deoxy-β-D-glucosylamine; N-Acetyl-beta-delta-glucosaminylamine; N-Acetyl-beta-D-glucosaminylamine; N-Acetyl-beta-glucosaminylamine; N-Acetyl-b-D-glucosaminylamine; N-acetyl-β-D-glucosaminylamine; N-Acetyl-b-glucosaminylamine
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:15947
- KEGG: C01239
- PubChem: 439454
- PubChem: 897
- HMDB: HMDB0001104
- Metlin: METLIN65570
- MetaCyc: N-ACETYL-BETA-GLUCOSAMINYLAMINE
- foodb: FDB022426
- chemspider: 388560
- CAS: 112339-01-2
- CAS: 114910-04-2
- CAS: 112339-04-5
- CAS: 18615-50-4
- CAS: 4229-38-3
- PMhub: MS000013589
- PubChem: 4460
- NIKKAJI: J1.311.394G
- RefMet: N-Acetyl-beta-glucosaminylamine
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-312
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
6 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(6)
- protein O-[N-acetyl]-glucosylation:
H2O + an N-acetyl-β-D-glucosaminyl-[glycoprotein] ⟶ N-acetyl-α-D-glucosamine + a [glycoprotein]-(L-serine/L-threonine) - protein O-[N-acetyl]-glucosylation:
H2O + an N-acetyl-β-D-glucosaminyl-[glycoprotein] ⟶ N-acetyl-α-D-glucosamine + a [glycoprotein]-(L-serine/L-threonine) - asparagine degradation:
2-oxoglutarate + asp ⟶ glu + oxaloacetate - L-asparagine degradation III (mammalian):
N4-(β-N-acetyl-D-glucosaminyl)-L-asparagine + H2O ⟶ N-acetyl-β-glucosaminylamine + H+ + asp - L-asparagine degradation III (mammalian):
2-oxoglutarate + asp ⟶ Glu + oxaloacetate - asparagine degradation III (mammalian):
2-oxoglutarate + asp ⟶ glt + oxaloacetate
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
