D-alpha-Aminobutyric acid (BioDeep_00000001196)
Secondary id: BioDeep_00000229604, BioDeep_00000270814
human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite
代谢物信息卡片
化学式: C4H9NO2 (103.0633)
中文名称: D-氨基丁酸
谱图信息:
最多检出来源 Homo sapiens(lipidomics) 27.89%
分子结构信息
SMILES: CCC(C(=O)O)N
InChI: InChI=1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m1/s1
描述信息
D-alpha-Aminobutyric acid (AABA), also known as alpha-aminobutyrate, (R)-2-aminobutanoic acid or D-homoalanine, belongs to the class of organic compounds known as D-alpha-amino acids. These are alpha amino acids which have the D-configuration of the alpha-carbon atom. D-alpha-aminobutyric acid is an optically active form of alpha-aminobutyric acid having D-configuration. It is an enantiomer of a L-alpha-aminobutyric acid and a non-proteinogenic amino acid. Alpha-aminobutyric acid is one of the three isomers of aminobutyric acid. The two others are the neurotransmitter Gamma-Aminobutyric acid (GABA) and Beta-Aminobutyric acid (BABA) which is known for inducing plant disease resistance. Optically active organic compounds found in meteorites typically exist in racemic form, yet life on Earth has almost exclusively selected for L- over D-enantiomers of amino acids. D-enantiomers of non-proteinogenic amino acids are known to inhibit aerobic microorganisms. D-alpha-aminobutyric acid has been shown to inhibit microbial iron reduction by a number of Geobacter strains including Geobacter bemidjiensis, Geobacter metallireducens and Geopsychrobacter electrodiphilus (PMID: 25695622). D-alpha-Aminobutyric acid is a known substrate of D-amino acid oxidase (PMID: 6127341).
Constituent of seedlings of Glycine max (soybean), Dolichos lablab (hyacinth bean), Canavalia gladiata (swordbean), Arachis hypogaea (peanut), Pisum sativum (pea), Phaseolus vulgaris (kidney bean) and Vigna sesquipedalis (asparagus bean) after hydrolysis
D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.
D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.
同义名列表
55 个代谢物同义名
alpha-Aminobutyric acid, (+-)-isomer; alpha-Aminobutyric acid, (R)-isomer; alpha-Aminobutyric acid, (S)-isomer; delta-alpha-Aminobutyric acid; delta-(-)-2-Aminobutyric acid; D-&alpha-Aminobutyric acid; delta-2-Aminobutanoic acid; (2S)-2-Aminobutanoic acid; (2R)-2-Aminobutanoic acid; delta-2-Aminobutyric acid; delta-2-Aminobuttersaeure; (R)-2-Amino-butanoic acid; D-alpha-Aminobutyric acid; D-(-)-2-Aminobutyric acid; (2R)-2-Aminobutyric acid; (R)-2-Aminobutanoic acid; alpha-Aminobutyric acid; (R)-2-Aminobutyric acid; 2R-amino-butanoic acid; delta-2-Aminobutanoate; D-2-Aminobutanoic acid; L-2-Aminobutyric acid; D-(-)-2-Aminobutyrate; D-2-Aminobutyric acid; (2R)-2-Aminobutanoate; (R)-2-Amino-butanoate; D-Α-aminobutyric acid; D-a-Aminobutyric acid; delta-2-Aminobutyrate; D-2-Aminobuttersaeure; D-alpha-Aminobutyrate; Butyrine, (+-)-isomer; 2-Aminobutanoic acid; (R)-2-Aminobutanoate; Butyrine, (S)-isomer; (2R)-2-Aminobutyrate; Butyrine, (R)-isomer; Α-aminobutyric acid; alpha-Aminobutyrate; 2-Aminobutyric acid; (R)-2-Aminobutyrate; a-Aminobutyric acid; 2R-Amino-butanoate; D-2-Aminobutanoate; D-2-Aminobutyrate; D-a-Aminobutyrate; D-Α-aminobutyrate; a-Aminobutyrate; Α-aminobutyrate; L-Homoalanine; Homoalanine; H-D-Abu-OH; Butyrine; D(-)-2-Aminobutyric acid; D-2-Aminobutyrate
数据库引用编号
20 个数据库交叉引用编号
- ChEBI: CHEBI:28797
- KEGG: C02261
- PubChem: 439691
- HMDB: HMDB0000650
- Metlin: METLIN35950
- Metlin: METLIN12
- DrugBank: DB04454
- ChEMBL: CHEMBL553426
- Wikipedia: Alpha-Aminobutyric acid
- MetaCyc: CPD0-1952
- foodb: FDB012680
- chemspider: 388757
- CAS: 2623-91-8
- PubChem: 5323
- LipidMAPS: LMFA01100043
- PDB-CCD: DBB
- 3DMET: B01551
- NIKKAJI: J1.815E
- medchemexpress: HY-Y0127
- KNApSAcK: 28797
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
