Lynestrenol (BioDeep_00000009416)

   


代谢物信息卡片


19-norpregn-4-en-20-yn-17alpha-ol

化学式: C20H28O (284.214)
中文名称: 利奈孕醇
谱图信息: 最多检出来源 Viridiplantae(plant) 12.4%

分子结构信息

SMILES: C#CC1(O)CCC2C3CCC4=CCCCC4C3CCC21C
InChI: InChI=1S/C20H28O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h1,6,15-18,21H,4-5,7-13H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1

描述信息

G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03A - Hormonal contraceptives for systemic use > G03AC - Progestogens
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03D - Progestogens > G03DC - Estren derivatives
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
Same as: D01580

同义名列表

4 个代谢物同义名

19-norpregn-4-en-20-yn-17alpha-ol; Lynestrenol; ST 20:3;O; Lynestrenol



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 APOB, CYP2C9, CYP3A4, ESR1, PF4, PGR, PRL
Peripheral membrane protein 1 ESR1
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 3 APOB, CYP2C9, CYP3A4
Nucleus 3 ESR1, PGR, PRL
cytosol 4 APOA1, APOB, ESR1, PGR
nucleoplasm 3 ESR1, PGR, PRL
RNA polymerase II transcription regulator complex 1 PRL
Cell membrane 1 ESR1
Cytoplasmic side 1 ESR1
Golgi apparatus 1 ESR1
Golgi membrane 1 INS
lysosomal membrane 1 CP
neuronal cell body 1 APOB
smooth endoplasmic reticulum 1 APOB
plasma membrane 10 APOA1, APOB, CP, CYP2C9, ESR1, F2, IFNLR1, PGR, REN, SERPINC1
Membrane 4 CYP3A4, ESR1, IFNLR1, REN
extracellular exosome 9 APOA1, APOB, CP, F2, PZP, SERPINA6, SERPINA7, SERPINC1, SHBG
extracellular space 14 AMH, APOA1, APOB, CP, F2, GNRH1, INS, PF4, PRL, PZP, REN, SERPINA6, SERPINA7, SERPINC1
lysosomal lumen 1 APOB
protein-containing complex 1 ESR1
intracellular membrane-bounded organelle 3 APOB, CYP2C9, CYP3A4
Microsome membrane 2 CYP2C9, CYP3A4
Single-pass type I membrane protein 1 IFNLR1
Secreted 10 AMH, APOA1, APOB, CP, F2, INS, PF4, PRL, REN, SHBG
extracellular region 15 AMH, APOA1, APOB, CP, F2, GNRH1, INS, PF4, PRL, PZP, REN, SERPINA6, SERPINA7, SERPINC1, SHBG
mitochondrial outer membrane 1 PGR
transcription regulator complex 1 ESR1
Extracellular vesicle 1 APOA1
chylomicron 2 APOA1, APOB
high-density lipoprotein particle 1 APOA1
low-density lipoprotein particle 2 APOA1, APOB
very-low-density lipoprotein particle 2 APOA1, APOB
cytoplasmic vesicle 1 APOA1
Early endosome 2 APOA1, APOB
apical part of cell 1 REN
collagen-containing extracellular matrix 4 APOA1, F2, PF4, SERPINC1
chromatin 3 ESR1, PGR, PRL
Secreted, extracellular space 1 SERPINC1
blood microparticle 5 APOA1, CP, F2, PZP, SERPINC1
endosome lumen 3 APOB, INS, PRL
Lipid droplet 1 APOB
euchromatin 1 ESR1
secretory granule lumen 2 APOA1, INS
Golgi lumen 2 F2, INS
endoplasmic reticulum lumen 6 APOA1, APOB, CP, F2, INS, SERPINC1
platelet alpha granule lumen 1 PF4
endocytic vesicle 1 APOA1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
endoplasmic reticulum exit site 1 APOB
clathrin-coated endocytic vesicle membrane 1 APOB
[Isoform 1]: Nucleus 1 ESR1
spherical high-density lipoprotein particle 1 APOA1
endocytic vesicle lumen 2 APOA1, APOB
chylomicron remnant 1 APOB
intermediate-density lipoprotein particle 1 APOB
mature chylomicron 1 APOB
[Isoform 4]: Mitochondrion outer membrane 1 PGR
interleukin-28 receptor complex 1 IFNLR1


文献列表

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  • Kimberly K Scarsi, Yoninah S Cramer, Susan L Rosenkranz, Francesca Aweeka, Baiba Berzins, Robert W Coombs, Kristine Coughlin, Laura E Moran, Carmen D Zorrilla, Victor Akelo, Mariam Aziz, Ruth K Friedman, David Gingrich, Shobha Swaminathan, Catherine Godfrey, Susan E Cohn. Antiretroviral therapy and vaginally administered contraceptive hormones: a three-arm, pharmacokinetic study. The lancet. HIV. 2019 09; 6(9):e601-e612. doi: 10.1016/s2352-3018(19)30155-9. [PMID: 31498109]
  • Jianjia Fan, Yoko Shimizu, Jeniffer Chan, Anna Wilkinson, Ayaka Ito, Peter Tontonoz, Edie Dullaghan, Liisa A M Galea, Tom Pfeifer, Cheryl L Wellington. Hormonal modulators of glial ABCA1 and apoE levels. Journal of lipid research. 2013 Nov; 54(11):3139-50. doi: 10.1194/jlr.m042473. [PMID: 23999864]
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