methoxychlor (BioDeep_00000858367)
Main id: BioDeep_00000008459
代谢物信息卡片
Benzene,1,1-(2,2,2-trichloroethylidene)bis[4-methoxy-
化学式: C16H15Cl3O2 (344.013758)
中文名称: 甲氧滴滴涕
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)C(Cl)(Cl)Cl
InChI: InChI=1S/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H3
描述信息
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:6842
- KEGG: C11043
- KEGGdrug: D91527
- PubChem: 4115
- ChEMBL: CHEMBL362919
- MeSH: Methoxychlor
- CAS: 1644449-82-0
- CAS: 72-43-5
- PubChem: 13226
- NIKKAJI: J2.377I
- KNApSAcK: 6842
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Patrycja Witek, Małgorzata Grzesiak, Marek Koziorowski, Maria Slomczynska, Katarzyna Knapczyk-Stwora. Long-Term Changes in Ovarian Follicles of Gilts Exposed Neonatally to Methoxychlor: Effects on Oocyte-Derived Factors, Anti-Müllerian Hormone, Follicle-Stimulating Hormone, and Cognate Receptors.
International journal of molecular sciences.
2022 Mar; 23(5):. doi:
10.3390/ijms23052780. [PMID: 35269923] - Hannes Reinwald, Julia Alvincz, Gabriela Salinas, Christoph Schäfers, Henner Hollert, Sebastian Eilebrecht. Toxicogenomic profiling after sublethal exposure to nerve- and muscle-targeting insecticides reveals cardiac and neuronal developmental effects in zebrafish embryos.
Chemosphere.
2022 Mar; 291(Pt 1):132746. doi:
10.1016/j.chemosphere.2021.132746. [PMID: 34748799] - Katarzyna Knapczyk-Stwora, Anna Nynca, Sylwia Swigonska, Lukasz Paukszto, Jan P Jastrzebski, Patrycja Witek, Marek Koziorowski, Maria Slomczynska. Effects of neonatal methoxychlor exposure on the ovarian transcriptome in piglets.
Animal reproduction science.
2022 Mar; 238(?):106956. doi:
10.1016/j.anireprosci.2022.106956. [PMID: 35231789] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Lin Cheng, Weiguo Song, Qinxiong Rao, Junliang Zhou, Zhihui Zhao. Bioaccumulation and toxicity of methoxychlor on Chinese mitten crab (Eriocheir sinensis).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2019 Jul; 221(?):89-95. doi:
10.1016/j.cbpc.2019.04.002. [PMID: 30954688] - Katarzyna Knapczyk-Stwora, Malgorzata Grzesiak, Renata E Ciereszko, Elzbieta Czaja, Marek Koziorowski, Maria Slomczynska. The impact of sex steroid agonists and antagonists on folliculogenesis in the neonatal porcine ovary via cell proliferation and apoptosis.
Theriogenology.
2018 Jun; 113(?):19-26. doi:
10.1016/j.theriogenology.2018.02.008. [PMID: 29452853] - Jitender Kumar Bhardwaj, Priyanka Saraf. N-acetyl cysteine-mediated effective attenuation of methoxychlor-induced granulosa cell apoptosis by counteracting reactive oxygen species generation in caprine ovary.
Environmental toxicology.
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Molecular reproduction and development.
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Aquatic toxicology (Amsterdam, Netherlands).
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2014 May; 15(5):7812-26. doi:
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PloS one.
2014; 9(7):e102091. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2013 Sep; 40(?):8-15. doi:
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Toxicology.
2013 Jul; 309(?):1-8. doi:
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Toxicology letters.
2013 Mar; 218(1):18-23. doi:
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Basic & clinical pharmacology & toxicology.
2012 Oct; 111(4):224-31. doi:
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PloS one.
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Toxicological sciences : an official journal of the Society of Toxicology.
2010 Dec; 118(2):653-66. doi:
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Neurotoxicology and teratology.
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Toxicological sciences : an official journal of the Society of Toxicology.
2009 Apr; 108(2):320-9. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
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Reproductive toxicology (Elmsford, N.Y.).
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Chemosphere.
2007 Apr; 67(9):S256-62. doi:
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Environmental research.
2007 Jan; 103(1):55-61. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2007 Jan; 95(1):74-81. doi:
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The Journal of steroid biochemistry and molecular biology.
2006 Dec; 102(1-5):175-9. doi:
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Environmental health perspectives.
2006 Aug; 114(8):1297-300. doi:
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Environmental health perspectives.
2006 Jul; 114(7):1133-8. doi:
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Toxicology letters.
2006 May; 163(2):142-52. doi:
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Brain research.
2006 Apr; 1081(1):9-18. doi:
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Environmental health perspectives.
2006 Apr; 114 Suppl 1(?):40-50. doi:
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Environmental health perspectives.
2006 Apr; 114 Suppl 1(?):106-14. doi:
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Journal of circadian rhythms.
2006 Mar; 4(?):3. doi:
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Reproductive biology and endocrinology : RB&E.
2006 Feb; 4(?):9. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2006 Feb; 21(2):148-53. doi:
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The Science of the total environment.
2005 Dec; 351-352(?):344-68. doi:
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Environmental health perspectives.
2005 Oct; 113(10):1318-24. doi:
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Domestic animal endocrinology.
2005 Aug; 29(2):411-9. doi:
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Reproductive biology and endocrinology : RB&E.
2005 May; 3(?):16. doi:
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Brain research bulletin.
2005 Apr; 65(3):199-209. doi:
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Environmental health perspectives.
2005 Apr; 113(4):391-5. doi:
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Environmental health perspectives.
2005 Mar; 113(3):323-8. doi:
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Environmental health perspectives.
2005 Mar; 113(3):297-303. doi:
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Environmental toxicology and chemistry.
2005 Mar; 24(3):665-73. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2005 Jan; 33(1):157-64. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2004 Dec; 82(2):598-607. doi:
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Environmental health perspectives.
2004 Nov; 112(15):1467-71. doi:
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Environmental research.
2004 Sep; 96(1):34-40. doi:
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The Journal of reproduction and development.
2004 Aug; 50(4):455-61. doi:
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Biomedical chromatography : BMC.
2004 Mar; 18(2):102-11. doi:
10.1002/bmc.300. [PMID: 15039962] - Wilfried Karmaus, Xiaobei Zhu. Maternal concentration of polychlorinated biphenyls and dichlorodiphenyl dichlorethylene and birth weight in Michigan fish eaters: a cohort study.
Environmental health : a global access science source.
2004 Jan; 3(1):1. doi:
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Current pharmaceutical design.
2004; 10(22):2749-57. doi:
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Cancer research.
2003 Nov; 63(21):7490-6. doi:
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Environmental health : a global access science source.
2003 Oct; 2(1):12. doi:
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Chemical research in toxicology.
2003 Oct; 16(10):1338-58. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2003 Jul; 74(1):103-13. doi:
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Medical science monitor : international medical journal of experimental and clinical research.
2003 May; 9(5):PI37-42. doi:
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Aquatic toxicology (Amsterdam, Netherlands).
2003 Feb; 62(3):179-94. doi:
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Archives of toxicology.
2002 Dec; 76(12):692-8. doi:
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