2'-Hydroxydaidzein (BioDeep_00000000850)

 

Secondary id: BioDeep_00000270317

human metabolite PANOMIX_OTCML-2023 Endogenous Volatile Flavor Compounds natural product


代谢物信息卡片


2,4,7-Trihydroxyisoflavone; 2-Hydroxydaidzein; 7,2,4-Trihydroxyisoflavone

化学式: C15H10O5 (270.052821)
中文名称: 7,2,4-三羟基异黄酮
谱图信息: 最多检出来源 Viridiplantae(plant) 0.08%

分子结构信息

SMILES: c1(ccc2c(c1)occ(c2=O)c1c(cc(cc1)O)O)O
InChI: InChI=1S/C15H10O5/c16-8-1-3-10(13(18)5-8)12-7-20-14-6-9(17)2-4-11(14)15(12)19/h1-7,16-18H

描述信息

2-hydroxydaidzein is a hydroxyisoflavone that is daidzein bearing an additional hydroxy substituent at position 2. It has a role as an anti-inflammatory agent. It is functionally related to a daidzein. It is a conjugate acid of a 2-hydroxydaidzein(1-).
2-Hydroxydaidzein is a natural product found in Viola hondoensis, Crotalaria pallida, and other organisms with data available.
Isolated from pods of Phaseolus vulgaris (kidney bean) and Phaseolus lunatus (butter bean). 2-Hydroxydaidzein is found in many foods, some of which are butternut squash, ginger, summer grape, and yam.
2-Hydroxydaidzein is found in common bean. 2-Hydroxydaidzein is isolated from pods of Phaseolus vulgaris (kidney bean) and Phaseolus lunatus (butter bean
A hydroxyisoflavone that is daidzein bearing an additional hydroxy substituent at position 2.
2′-Hydroxydaidzein is a metabolite. 2′-Hydroxydaidzein inhibits the release of chemical mediator from inflammatory cells. 2′-Hydroxydaidzein significantly inhibits lysozyme and β-glucuronidase release from rat neutrophils, which is stimulated with fMLP/CB, respectively[1].

同义名列表

19 个代谢物同义名

2,4,7-Trihydroxyisoflavone; 2-Hydroxydaidzein; 7,2,4-Trihydroxyisoflavone; 3-(2,4-Dihydroxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one, 9CI; 4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-7-hydroxy-; 3-(2,4-Dihydroxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one; 3-(2,4-dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one; 3-(2,4-Dihydroxy-phenyl)-7-hydroxy-chromen-4-one; 3-(2,4-Dihydroxy-phenyl)-7-hvdroxy-chromen-4-one; 3-(2,4-dihydroxyphenyl)-7-hydroxychromen-4-one; 2 inverted exclamation marka-Hydroxydaidzein; ZCTNPCRBEWXCGP-UHFFFAOYSA-N; 2,4,7-trihydroxyisoflavone; 7,2,4-trihydroxyisoflavone; 2-Hydroxydaidzein; 2-hydroxydaidzein; UNII-4GQ94T5E87; 2,4,7-THIF; 4GQ94T5E87; 2′-Hydroxydaidzein; 2'-Hydroxydaidzein



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(2)

代谢反应

16 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(3)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(13)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

28 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hyung-In Moon, Joongku Lee, Jong Hwan Kwak, Ok-Pyo Zee, Jin Ho Chung. Isoflavonoid from Viola hondoensis, regulates the expression of matrix metalloproteinase-1 in human skin fibroblasts. Biological & pharmaceutical bulletin. 2005 May; 28(5):925-8. doi: 10.1248/bpb.28.925. [PMID: 15863909]
  • Hun Sung Yoo, Ji Suk Lee, Chul Young Kim, Jinwoong Kim. Flavonoids of Crotalaria sessiliflora. Archives of pharmacal research. 2004 May; 27(5):544-6. doi: 10.1007/bf02980129. [PMID: 15202561]
  • Horng-Huey Ko, Jing-Ru Weng, Lo-Ti Tsao, Ming-Hong Yen, Jih-Pyang Wang, Chun-Nan Lin. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorganic & medicinal chemistry letters. 2004 Feb; 14(4):1011-4. doi: 10.1016/j.bmcl.2003.11.074. [PMID: 15013012]