O,O,S-trimethyl phosphorothiate (BioDeep_00000810648)
代谢物信息卡片
化学式: C3H9O3PS (156.001)
中文名称: O,O,S-三甲基酯硫代磷酸, O、 O,S-三甲基硫代磷酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COP(=O)(OC)SC
InChI: InChI=1S/C3H9O3PS/c1-5-7(4,6-2)8-3/h1-3H3
描述信息
同义名列表
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Linfang Huang, Megumi Toyoshima, Akihiro Asakawa, Kayoko Inoue, Kouji Harada, Tomomi Kinoshita, Shilin Chen, Akio Koizumi. Levels of N-acylethanolamines in O,O,S-trimethylphosphorothioate (OOS-TMP)-treated C57BL/6J mice and potential anti-obesity, anti-diabetic effects of OOS-TMP in hyperphagia and hyperglycemia mouse models.
Pharmacology, biochemistry, and behavior.
2009 Mar; 92(1):1-5. doi:
10.1016/j.pbb.2008.10.003
. [PMID: 18992273] - Linfang Huang, Megumi Toyoshima, Akihiro Asakawa, Kayoko Inoue, Kouji Harada, Tomomi Kinoshita, Akio Koizumi. Roles of neuropeptides in O,O,S-trimethylphosphorothioate (OOS-TMP)-induced anorexia in mice.
Biochemical and biophysical research communications.
2007 Oct; 362(1):177-182. doi:
10.1016/j.bbrc.2007.07.174
. [PMID: 17698039] - K Ohtaka, A Koizumi. Enhanced levels of lipid peroxidation and xanthine oxidase activity in the lung of male Sprague-Dawley rats following treatment with O,O,S-trimethyl phosphorothioate.
Pharmacology & toxicology.
1994 Sep; 75(3-4):206-11. doi:
10.1111/j.1600-0773.1994.tb00348.x
. [PMID: 7800664] - S Keadtisuke, W Dheranetra, T Nakatsugawa, T R Fukuto. Liver damage induced in rats by malathion impurities.
Toxicology letters.
1990 Jun; 52(1):35-46. doi:
10.1016/0378-4274(90)90163-g
. [PMID: 2356569] - D Dinsdale, R D Verschoyle. Ultrastructural effects of phosphorothionates and other inhibitors of lung monooxygenases: protection against trialkylphosphorothiolate-induced lung injury.
Experimental lung research.
1989 May; 15(3):459-71. doi:
10.3109/01902148909087871
. [PMID: 2787242] - S Keadtisuke, W Dheranetra, T R Fukuto. Detection of kidney damage by malathion impurities using a microdissection technique.
Toxicology letters.
1989 Apr; 47(1):53-9. doi:
10.1016/0378-4274(89)90085-4
. [PMID: 2652380] - M L Bezençon, S K Durham, J Roux, E M Grandjean, T Imamura. A pneumotoxin, O,O,S-trimethyl phosphorothioate, induces hemorheological alteration in rats.
Archives of toxicology.
1989; 63(4):325-30. doi:
10.1007/bf00278647
. [PMID: 2764721] - J Hasegawa, M Suzuki, Y Wada, S Kamiyama, A Koizumi. Hyperethanolaminuria in O, O, S-trimethyl phosphorothioate toxicity in rats.
Industrial health.
1988; 26(4):215-23. doi:
10.2486/indhealth.26.215
. [PMID: 3230054] - S Keadtisuke, T R Fukuto. Dysproteinuria induced in rats by O,O,S-trimethyl phosphorothioate.
Toxicology letters.
1987 Jun; 37(1):33-9. doi:
10.1016/0378-4274(87)90164-0
. [PMID: 3590228] - K E Rodgers, T Imamura, B H Devens. Organophosphorus pesticide immunotoxicity: effects of O,O,S-trimethyl phosphorothioate on cellular and humoral immune response systems.
Immunopharmacology.
1986 Dec; 12(3):193-202. doi:
10.1016/0162-3109(86)90003-2
. [PMID: 3493228] - A Koizumi, V Tada, T Imamura. Similarity of isozyme pattern of serum lactate dehydrogenase following treatments with O,O,S-trimethyl phosphorothioate and paraquat.
Toxicology letters.
1986 Apr; 31(1):85-90. doi:
10.1016/0378-4274(86)90197-9
. [PMID: 3715918] - T Imamura, I K Thomas. Alterations of alveolar macrophage function and level of bronchopulmonary protease inhibitors in O,O,S-trimethyl phosphorothioate-induced lung injury.
Toxicology.
1985 Oct; 37(1-2):79-89. doi:
10.1016/0300-483x(85)90114-3
. [PMID: 4060171] - T R Fukuto. Toxicological properties of trialkyl phosphorothioate and dialkyl alkyl- and arylphosphonothioate esters.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
1983; 18(1):89-117. doi:
10.1080/03601238309372359
. [PMID: 6833715] - S G Lee, T R Fukuto. Inhibition of rat liver and plasma carboxylesterases by impurities present in technical phenthoate.
Journal of toxicology and environmental health.
1982 Oct; 10(4-5):717-28. doi:
10.1080/15287398209530290
. [PMID: 7161823] - N Umetsu, N M Mallipudi, R F Toia, R B March, T R Fukuto. Toxicological properties of phosphorothioate and related esters present as impurities in technical organophosphorus insecticides.
Journal of toxicology and environmental health.
1981 Mar; 7(3-4):481-97. doi:
10.1080/15287398109529996
. [PMID: 7288900] - L Giuliani, G Carmignani, E Belgrano, P Puppo. Transcatheter arterial embolization in urological tumors: the use of isobutyl-2-cyanoacrylate.
The Journal of urology.
1979 May; 121(5):630-4. doi:
10.1016/s0022-5347(17)56913-x
. [PMID: 439260]