Bursehernin (BioDeep_00000000802)

   

PANOMIX_OTCML-2023


代谢物信息卡片


2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-((3,4-dimethoxyphenyl )methyl)dihydro-, (3R-trans)-

化学式: C21H22O6 (370.1416)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 19.75%

分子结构信息

SMILES: COC1=C(C=C(C=C1)CC2C(COC2=O)CC3=CC4=C(C=C3)OCO4)OC
InChI: InChI=1S/C21H22O6/c1-23-17-5-3-14(9-19(17)24-2)8-16-15(11-25-21(16)22)7-13-4-6-18-20(10-13)27-12-26-18/h3-6,9-10,15-16H,7-8,11-12H2,1-2H3/t15-,16+/m0/s1

描述信息

(-)-bursehernin is a butan-4-olide that is (-)-pluviatolide in which the phenolic hydroxy group has been converted to the corresponding methyl ether. It has a role as a plant metabolite. It is an aromatic ether, a member of benzodioxoles, a butan-4-olide and a lignan. It is functionally related to a (-)-pluviatolide.
Bursehernin is a natural product found in Zanthoxylum beecheyanum, Hernandia nymphaeifolia, and other organisms with data available.
A butan-4-olide that is (-)-pluviatolide in which the phenolic hydroxy group has been converted to the corresponding methyl ether.

同义名列表

13 个代谢物同义名

2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-((3,4-dimethoxyphenyl )methyl)dihydro-, (3R-trans)-; 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-((3,4-dimethoxyphenyl)methyl)dihydro-, (3R-trans)-; (3R-trans)-4-(1,3-benzodioxol-5-ylmethyl)-3-((3,4-dimethoxyphenyl)methyl)dihydro-2(3H)-furanone; (3R-trans)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methyl]dihydro-2(3H)-furanone; (3R,4R)-4-(2H-1,3-Benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methyl]oxolan-2-one; (3R,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(3,4-dimethoxybenzyl)dihydrofuran-2(3H)-one; (R,R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(3,4-dimethoxybenzyl)dihydrofuran-2(3H)-one; (3R,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methyl]oxolan-2-one; 4-[(2H-1,3-Benzodioxol-5-yl)methyl]-3-[(3,4-dimethoxyphenyl)methyl]oxolan-2-one; (-)-5-desmethoxy-yatein; (-)-bursehernin; Bursehernin; MEGxp0_001223



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(2)

  • yatein biosynthesis I: (-)-bursehernin + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ (-)-5'-demethylyatein + H2O + an oxidized [NADPH-hemoprotein reductase]
  • yatein biosynthesis I: (-)-pluviatolide + SAM ⟶ (-)-bursehernin + H+ + SAH

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

13 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ADCY10, C1orf116, CCND1, PTGS2, STAT3
Peripheral membrane protein 3 ADCY10, GORASP1, PTGS2
Endoplasmic reticulum membrane 2 HSP90B1, PTGS2
Nucleus 4 ADCY10, CCND1, HSP90B1, STAT3
cytosol 5 ADCY10, C1orf116, CCND1, HSP90B1, STAT3
dendrite 1 ADCY10
centrosome 1 CCND1
nucleoplasm 2 CCND1, STAT3
RNA polymerase II transcription regulator complex 1 STAT3
Cell membrane 1 ADCY10
Cytoplasmic side 2 ADCY10, GORASP1
Golgi apparatus membrane 1 GORASP1
glutamatergic synapse 1 C1QL3
Golgi apparatus 1 GORASP1
Golgi membrane 1 GORASP1
neuronal cell body 1 ADCY10
smooth endoplasmic reticulum 1 HSP90B1
plasma membrane 2 C1orf116, STAT3
Membrane 1 HSP90B1
apical plasma membrane 1 ADCY10
caveola 1 PTGS2
extracellular exosome 2 C1orf116, HSP90B1
endoplasmic reticulum 2 HSP90B1, PTGS2
perinuclear region of cytoplasm 2 ADCY10, HSP90B1
bicellular tight junction 1 CCND1
mitochondrion 1 ADCY10
protein-containing complex 2 HSP90B1, PTGS2
Microsome membrane 1 PTGS2
Secreted 1 C1QL3
extracellular region 2 ADCY10, HSP90B1
astrocyte end-foot 1 ADCY10
basal part of cell 1 ADCY10
central region of growth cone 1 ADCY10
hippocampal mossy fiber to CA3 synapse 1 C1QL3
transcription regulator complex 1 STAT3
Cell projection, cilium 1 ADCY10
Nucleus membrane 1 CCND1
nuclear membrane 1 CCND1
midbody 1 HSP90B1
Cytoplasm, perinuclear region 1 ADCY10
Cytoplasm, cytoskeleton 1 ADCY10
focal adhesion 1 HSP90B1
cis-Golgi network 1 GORASP1
collagen trimer 1 C1QL3
collagen-containing extracellular matrix 1 HSP90B1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
cilium 1 ADCY10
chromatin 1 STAT3
cytoskeleton 1 ADCY10
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
endoplasmic reticulum lumen 2 HSP90B1, PTGS2
transcription repressor complex 1 CCND1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
Sarcoplasmic reticulum lumen 1 HSP90B1
synaptic cleft 1 C1QL3
cyclin-dependent protein kinase holoenzyme complex 1 CCND1
endocytic vesicle lumen 1 HSP90B1
endoplasmic reticulum chaperone complex 1 HSP90B1
cyclin D1-CDK4 complex 1 CCND1
cyclin D1-CDK6 complex 1 CCND1


文献列表

  • Warren Lau, Elizabeth S Sattely. Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone. Science (New York, N.Y.). 2015 Sep; 349(6253):1224-8. doi: 10.1126/science.aac7202. [PMID: 26359402]
  • H Yamaguchi, M Arimoto, K Yamamoto, A Numata. [Studies on the constituents of the seeds of Hernandia ovigera L. (author's transl)]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1979 Jun; 99(6):674-7. doi: 10.1248/yakushi1947.99.6_674. [PMID: 231650]