Caranine (BioDeep_00000007801)

   

natural product


代谢物信息卡片


NSC406043

化学式: C16H17NO3 (271.1208)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 15.16%

分子结构信息

SMILES: C1CN2CC3=CC4=C(C=C3C5C2C1=CCC5O)OCO4
InChI: InChI=1S/C16H17NO3/c18-12-2-1-9-3-4-17-7-10-5-13-14(20-8-19-13)6-11(10)15(12)16(9)17/h1,5-6,12,15-16,18H,2-4,7-8H2/t12-,15-,16-/m1/s1

描述信息

An indolizidine alkaloid that is galanthan substituted by analpha-hydroxy group at position 1 and a methylenedioxy group across position 9 and 10. An alkaloid commonly found in the members of the family amaryllidaceae.

同义名列表

3 个代谢物同义名

Caranine; NSC406043; Caranine



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

  • Amaryllidacea alkaloids biosynthesis: 4'-O-methylnorbelladine + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ (4aS,10bR)-noroxomaritidine + H2O + an oxidized [NADPH-hemoprotein reductase]

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

20 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 2 CDK16, CTNNB1
Peripheral membrane protein 1 CDK16
Nucleus 2 CDK16, CTNNB1
cytosol 2 CDK16, CTNNB1
centrosome 1 CTNNB1
nucleoplasm 1 CTNNB1
Cell membrane 2 CDK16, CTNNB1
Cytoplasmic side 1 CDK16
lamellipodium 1 CTNNB1
Synapse 1 CTNNB1
cell cortex 1 CTNNB1
cell junction 1 CTNNB1
glutamatergic synapse 1 CTNNB1
presynaptic membrane 1 CTNNB1
synaptic vesicle 1 CDK16
Cytoplasmic vesicle, secretory vesicle 1 CDK16
plasma membrane 2 CDK16, CTNNB1
Membrane 1 CTNNB1
basolateral plasma membrane 1 CTNNB1
extracellular exosome 1 CTNNB1
perinuclear region of cytoplasm 1 CTNNB1
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
protein-containing complex 1 CTNNB1
cytoplasmic side of plasma membrane 1 CDK16
transcription regulator complex 1 CTNNB1
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
microtubule cytoskeleton 1 CDK16
Wnt signalosome 1 CTNNB1
apical part of cell 1 CTNNB1
cell-cell junction 1 CTNNB1
postsynaptic membrane 1 CTNNB1
Cytoplasm, cytoskeleton 1 CTNNB1
focal adhesion 1 CTNNB1
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
fascia adherens 1 CTNNB1
lateral plasma membrane 1 CTNNB1
neuron projection 1 CDK16
cell periphery 1 CTNNB1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
spindle pole 1 CTNNB1
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
Endomembrane system 1 CTNNB1
euchromatin 1 CTNNB1
beta-catenin-TCF complex 1 CTNNB1
presynaptic active zone cytoplasmic component 1 CTNNB1
Synapse, synaptosome 1 CDK16
protein-DNA complex 1 CTNNB1
catenin complex 1 CTNNB1
cyclin-dependent protein kinase holoenzyme complex 1 CDK16
beta-catenin-TCF7L2 complex 1 CTNNB1
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1


文献列表

  • Jerald J Nair, Anke Wilhelm, Susanna L Bonnet, Johannes van Staden. Antibacterial constituents of the plant family Amaryllidaceae. Bioorganic & medicinal chemistry letters. 2017 11; 27(22):4943-4951. doi: 10.1016/j.bmcl.2017.09.052. [PMID: 29033234]
  • M H Salehi Sourmaghi, B Azadi, Gh Amin, M Amini, M Sharifzadeh. The first phytochemical report of Galanthus transcaucasicus Fomin. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. 2010; 18(2):124-7. doi: . [PMID: 22615606]
  • M A Aboul-Ela, A M El-Lakany, H M Hammoda. Alkaloids from the bulbs of Crinum bulbispermum. Die Pharmazie. 2004 Nov; 59(11):894-6. doi: . [PMID: 15587597]