Eremanthin (BioDeep_00000007347)

 

Secondary id: BioDeep_00000420927, BioDeep_00000868839

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


(3aS,6aR,9aR,9bS)-6-methyl-3,9-dimethylidene-2H,3H,3aH,4H,6aH,7H,8H,9H,9aH,9bH-azuleno[4,5-b]furan-2-one

化学式: C15H18O2 (230.1306728)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 8%

分子结构信息

SMILES: C=C1C(=O)OC2C1CC=C(C)C1CCC(=C)C12
InChI: InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h4,11-14H,2-3,5-7H2,1H3/t11-,12-,13-,14-/m0/s1

描述信息

Eremanthin belongs to guaianolides and derivatives class of compounds. Those are diterpene lactones with a structure characterized by the presence of a gamma-lactone fused to a guaiane, forming 3,6,9-trimethyl-azuleno[4,5-b]furan-2-one or a derivative. Eremanthin is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Eremanthin can be found in sweet bay, which makes eremanthin a potential biomarker for the consumption of this food product.

同义名列表

4 个代谢物同义名

(3aS,6aR,9aR,9bS)-6-methyl-3,9-dimethylidene-2H,3H,3aH,4H,6aH,7H,8H,9H,9aH,9bH-azuleno[4,5-b]furan-2-one; Eremanthine; Vanillosmin; Eremanthin



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

23 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ashish Kumar, Antim K Maurya, Gopi Chand, Vijai K Agnihotri. Comparative metabolic profiling of Costus speciosus leaves and rhizomes using NMR, GC-MS and UPLC/ESI-MS/MS. Natural product research. 2018 Apr; 32(7):826-833. doi: 10.1080/14786419.2017.1365069. [PMID: 28814124]
  • Veeramuthu Duraipandiyan, Naif Abdullah Al-Harbi, Savarimuthu Ignacimuthu, Chinnasamy Muthukumar. Antimicrobial activity of sesquiterpene lactones isolated from traditional medicinal plant, Costus speciosus (Koen ex.Retz.) Sm. BMC complementary and alternative medicine. 2012 Mar; 12(?):13. doi: 10.1186/1472-6882-12-13. [PMID: 22397713]
  • J Eliza, P Daisy, S Ignacimuthu. Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm. Chemico-biological interactions. 2010 Dec; 188(3):467-72. doi: 10.1016/j.cbi.2010.08.002. [PMID: 20709041]
  • J Eliza, P Daisy, S Ignacimuthu, V Duraipandiyan. Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.)Sm., in STZ-induced diabetic rats. Chemico-biological interactions. 2009 Nov; 182(1):67-72. doi: 10.1016/j.cbi.2009.08.012. [PMID: 19695236]
  • F da L Dias, C S Takahashi, E Sakamoto-Hojo, W Vichnewski, S J Sarti. Genotoxicity of the natural cercaricides "sucupira" oil and eremanthine in mammalian cells in vitro and in vivo. Environmental and molecular mutagenesis. 1995; 26(4):338-44. doi: 10.1002/em.2850260410. [PMID: 8575423]
  • P M Baker, C C Fortes, E G Fortes, G Gazzinelli, B Gilbert, J N Lopes, J Pellegrino, T C Tomassini, W Vichnewski. Chemoprophylactic agents in schistosomiasis: eremanthine, costunolide, -cyclocostunolide and bisabolol. The Journal of pharmacy and pharmacology. 1972 Nov; 24(11):853-7. doi: 10.1111/j.2042-7158.1972.tb08903.x. [PMID: 4405647]