Mammeisin (BioDeep_00000007269)

 

Secondary id: BioDeep_00000270507, BioDeep_00000640982, BioDeep_00001892625

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


5,7-Dihydroxy-8-(3-methyl-2-butenyl)-6-(3-methyl-1-oxobutyl)-4-phenyl-2H-1-benzopyran-2-one, 9ci

化学式: C25H26O5 (406.178)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 55.37%

分子结构信息

SMILES: c1(c(c(c2c(c1O)c(cc(=O)o2)c1ccccc1)CC=C(C)C)O)C(=O)CC(C)C
InChI: InChI=1S/C25H26O5/c1-14(2)10-11-17-23(28)22(19(26)12-15(3)4)24(29)21-18(13-20(27)30-25(17)21)16-8-6-5-7-9-16/h5-10,13,15,28-29H,11-12H2,1-4H3

描述信息

Mammeisin is found in fruits. Mammeisin is a constituent of Mammea americana (mamey)
Constituent of Mammea americana (mamey). Mammeisin is found in fruits.

同义名列表

9 个代谢物同义名

5,7-Dihydroxy-8-(3-methyl-2-butenyl)-6-(3-methyl-1-oxobutyl)-4-phenyl-2H-1-benzopyran-2-one, 9ci; 5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-6-(3-methylbutanoyl)-4-phenyl-2H-chromen-2-one; 5,7-Dihydroxy-8-(3-methyl-2-butenyl)-6-(3-methylbutyryl)-4-phenylcoumarin; 5,7-Dihydroxy-8-isopentenyl-6-isovaleroyl-4-phenylcoumarin; Mammea A/AA; Mammeisin; Mammea A; AA; Mammeisin



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

45 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 MAPK14, MAPK8, STAT3, TNFSF11
Peripheral membrane protein 2 CYP1B1, GORASP1
Endoplasmic reticulum membrane 1 CYP1B1
Nucleus 5 JUND, MAPK14, MAPK8, RORC, STAT3
cytosol 4 ACP5, MAPK14, MAPK8, STAT3
nuclear body 2 CSF1, RORC
nucleoplasm 5 JUND, MAPK14, MAPK8, RORC, STAT3
RNA polymerase II transcription regulator complex 2 JUND, STAT3
Cell membrane 4 CSF1, IL23R, TNF, TNFSF11
Cytoplasmic side 1 GORASP1
Golgi apparatus membrane 1 GORASP1
Synapse 1 MAPK8
cell surface 2 IL23R, TNF
glutamatergic synapse 1 MAPK14
Golgi apparatus 1 GORASP1
Golgi membrane 1 GORASP1
neuronal cell body 1 TNF
Lysosome 1 ACP5
plasma membrane 5 CSF1, IL23R, STAT3, TNF, TNFSF11
Membrane 5 ACP5, CSF1, CYP1B1, IL23R, TNFSF11
axon 1 MAPK8
extracellular space 5 CSF1, CXCL2, IL22, TNF, TNFSF11
perinuclear region of cytoplasm 1 CSF1
mitochondrion 2 CYP1B1, MAPK14
intracellular membrane-bounded organelle 1 CYP1B1
Microsome membrane 1 CYP1B1
Single-pass type I membrane protein 2 CSF1, IL23R
Secreted 2 IL22, TNFSF11
extracellular region 6 CSF1, CXCL2, IL22, MAPK14, TNF, TNFSF11
transcription regulator complex 2 JUND, STAT3
external side of plasma membrane 2 IL23R, TNF
recycling endosome 1 TNF
Single-pass type II membrane protein 2 TNF, TNFSF11
Membrane raft 1 TNF
cis-Golgi network 1 GORASP1
nuclear speck 1 MAPK14
receptor complex 1 IL23R
chromatin 3 JUND, RORC, STAT3
phagocytic cup 1 TNF
spindle pole 1 MAPK14
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 1 MAPK14
endoplasmic reticulum lumen 1 CSF1
transcription repressor complex 1 JUND
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
[Isoform 2]: Cytoplasm 1 TNFSF11
[Tumor necrosis factor ligand superfamily member 11, soluble form]: Secreted 1 TNFSF11
basal dendrite 1 MAPK8
interleukin-23 receptor complex 1 IL23R
transcription factor AP-1 complex 1 JUND
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
CSF1-CSF1R complex 1 CSF1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Jules-Blaise Mabou Leuna, Sergeot Kungo Sop, Suzanne Makota, Evangeline Njanja, Thiery Christophe Ebelle, Anatole Guy Azebaze, Emmanuel Ngameni, Achille Nassi. Voltammetric behavior of Mammeisin (MA) at a glassy carbon electrode and its interaction with Bovine Serum Albumin (BSA). Bioelectrochemistry (Amsterdam, Netherlands). 2018 Feb; 119(?):20-25. doi: 10.1016/j.bioelechem.2017.08.008. [PMID: 28889056]
  • Lin Du, Fakhri Mahdi, Mika B Jekabsons, Dale G Nagle, Yu-Dong Zhou. Natural and semisynthetic mammea-type isoprenylated dihydroxycoumarins uncouple cellular respiration. Journal of natural products. 2011 Feb; 74(2):240-8. doi: 10.1021/np100762s. [PMID: 21214226]
  • A B Dongmo, A G B Azebaze, T B Nguelefack, B M Ouahouo, B Sontia, M Meyer, A E Nkengfack, A Kamanyi, W Vierling. Vasodilator effect of the extracts and some coumarins from the stem bark of Mammea africana (Guttiferae). Journal of ethnopharmacology. 2007 May; 111(2):329-34. doi: 10.1016/j.jep.2006.11.026. [PMID: 17204384]
  • José L López-Pérez, Dionisio A Olmedo, Esther Del Olmo, Yelkaira Vásquez, Pablo N Solís, Mahabir P Gupta, Arturo San Feliciano. Cytotoxic 4-phenylcoumarins from the leaves of Marila pluricostata. Journal of natural products. 2005 Mar; 68(3):369-73. doi: 10.1021/np049642g. [PMID: 15787438]