Adynerin (BioDeep_00000007007)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Adynerigenin 3-O-beta-D-diginoside

化学式: C30H44O7 (516.3087)
中文名称: 欧夹竹桃苷乙
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(C(CC(O1)OC2CCC3(C(C2)CCC45C3CCC6(C4(O5)CCC6C7=CC(=O)OC7)C)C)OC)O
InChI: InChI=1S/C30H44O7/c1-17-26(32)22(33-4)15-25(35-17)36-20-6-9-27(2)19(14-20)5-11-29-23(27)8-10-28(3)21(7-12-30(28,29)37-29)18-13-24(31)34-16-18/h13,17,19-23,25-26,32H,5-12,14-16H2,1-4H3/t17-,19-,20+,21-,22-,23-,25+,26+,27+,28-,29+,30-/m1/s1

描述信息

Adynerin is a natural steroid found in the herbs of Nerium oleander.

同义名列表

4 个代谢物同义名

Adynerin; Adynerigenin 3-O-beta-D-diginoside; NSC251673; Adynerin



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

20 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ABCB1, EGFR, GSTP1, TP53, TUBB4B, WT1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 1 EGFR
Mitochondrion membrane 1 ABCG2
Nucleus 5 EGFR, GSTP1, TP53, TUBB4B, WT1
cytosol 4 GSTP1, TP53, TUBB4B, WT1
mitochondrial membrane 1 ABCG2
centrosome 1 TP53
nucleoplasm 3 ABCG2, TP53, WT1
Cell membrane 5 ABCB1, ABCB5, ABCC1, ABCG2, EGFR
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 4 ABCB1, ABCB5, ABCC1, ABCG2
cell junction 1 EGFR
cell surface 2 ABCB1, EGFR
glutamatergic synapse 1 EGFR
Golgi membrane 1 EGFR
endosome 1 EGFR
plasma membrane 5 ABCB1, ABCB5, ABCC1, ABCG2, EGFR
Membrane 6 ABCB1, ABCB5, ABCC1, ABCG2, EGFR, TP53
apical plasma membrane 4 ABCB1, ABCC1, ABCG2, EGFR
basolateral plasma membrane 2 ABCC1, EGFR
extracellular exosome 4 ABCB1, ABCC1, GSTP1, TUBB4B
endoplasmic reticulum 1 TP53
extracellular space 2 EGFR, GSTP1
perinuclear region of cytoplasm 1 EGFR
mitochondrion 2 GSTP1, TP53
protein-containing complex 2 EGFR, TP53
Single-pass type I membrane protein 1 EGFR
extracellular region 2 GSTP1, TUBB4B
Mitochondrion matrix 1 TP53
mitochondrial matrix 1 TP53
transcription regulator complex 1 TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
nuclear membrane 1 EGFR
Extracellular vesicle 1 TUBB4B
microtubule cytoskeleton 1 TUBB4B
nucleolus 2 TP53, WT1
vesicle 1 GSTP1
Apical cell membrane 2 ABCB1, ABCG2
Membrane raft 2 ABCG2, EGFR
Cytoplasm, cytoskeleton 2 TP53, TUBB4B
focal adhesion 1 EGFR
microtubule 1 TUBB4B
intracellular vesicle 1 EGFR
Nucleus, PML body 1 TP53
PML body 1 TP53
lateral plasma membrane 1 ABCC1
nuclear speck 1 WT1
receptor complex 1 EGFR
chromatin 1 TP53
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
brush border membrane 1 ABCG2
site of double-strand break 1 TP53
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
axonemal microtubule 1 TUBB4B
Nucleus speckle 1 WT1
germ cell nucleus 1 TP53
replication fork 1 TP53
basal plasma membrane 2 ABCC1, EGFR
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 GSTP1
secretory granule lumen 1 GSTP1
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
azurophil granule lumen 1 TUBB4B
clathrin-coated endocytic vesicle membrane 1 EGFR
[Isoform 1]: Nucleus 1 TP53
external side of apical plasma membrane 2 ABCB1, ABCG2
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
TRAF2-GSTP1 complex 1 GSTP1
[Isoform 1]: Nucleus speckle 1 WT1
[Isoform 4]: Nucleus, nucleoplasm 1 WT1


文献列表

  • Ming Zhao, Liming Bai, Liyan Wang, Asami Toki, Toshiaki Hasegawa, Midori Kikuchi, Mariko Abe, Jun-ichi Sakai, Ryo Hasegawa, Yuhua Bai, Tomokazu Mitsui, Hirotsugu Ogura, Takao Kataoka, Seiko Oka, Hiroko Tsushima, Miwa Kiuchi, Katutoshi Hirose, Akihiro Tomida, Takashi Tsuruo, Masayoshi Ando. Bioactive cardenolides from the stems and twigs of Nerium oleander. Journal of natural products. 2007 Jul; 70(7):1098-103. doi: 10.1021/np068066g. [PMID: 17595134]