Cucurbitacin F (BioDeep_00000006985)

PANOMIX_OTCML-2023 Volatile Flavor Compounds natural product

代谢物信息卡片

2,3,16,20,25-Pentahydroxy-9-methyl-19-norlanosta-5,23-diene-11,22-dione (2beta,3alpha,9beta,10alpha,16alpha,23E)-

化学式: C30H46O7 (518.3243365999999)
中文名称: 葫芦素F
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 1.82%

分子结构信息

SMILES: CC(C)(/C=C/C(=O)[C@@](C)([C@H]1[C@@H](C[C@@]2(C)[C@@H]3CC=C4[C@@H](C[C@@H]([C@H](C4(C)C)O)O)[C@]3(C)C(=O)C[C@]12C)O)O)O
InChI: InChI=1S/C30H46O7/c1-25(2,36)12-11-21(33)30(8,37)23-19(32)14-27(5)20-10-9-16-17(13-18(31)24(35)26(16,3)4)29(20,7)22(34)15-28(23,27)6/h9,11-12,17-20,23-24,31-32,35-37H,10,13-15H2,1-8H3/b12-11+/t17-,18+,19-,20+,23+,24-,27+,28-,29+,30+/m1/s1

描述信息

同义名列表

5 个代谢物同义名

2,3,16,20,25-Pentahydroxy-9-methyl-19-norlanosta-5,23-diene-11,22-dione (2beta,3alpha,9beta,10alpha,16alpha,23E)-; Cucurbitacin F; ST 30:4;O7; Cucurbitacin O; Cucurbitacin F

数据库引用编号

17 个数据库交叉引用编号

ChEBI: CHEBI:3945
KEGG: C08798
PubChem: 5281320
PubChem: 429242
Metlin: METLIN41671
ChEMBL: CHEMBL488312
LipidMAPS: LMST01010108
KNApSAcK: C00003687
CAS: 5939-57-1
PMhub: MS000020202
MetaboLights: MTBLC3945
PubChem: 10991
3DMET: B02419
NIKKAJI: J8.309G
RefMet: Cucurbitacin F
KNApSAcK: 3945
LOTUS: LTS0228811

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

41 个相关的物种来源信息

3681 - Begonia: LTS0228811
78253 - Begonia nantoensis: 10.1002/CHIN.200434239
78253 - Begonia nantoensis: 10.1248/CPB.52.345
78253 - Begonia nantoensis: LTS0228811
3680 - Begoniaceae: LTS0228811
386143 - Cayaponia: LTS0228811
3650 - Cucurbitaceae: LTS0228811
392618 - Cunila: 10.1007/S00299-018-2303-8
392618 - Cunila: LTS0228811
25932 - Datisca: LTS0228811
34297 - Datisca glomerata: 10.1039/P19830001333
34297 - Datisca glomerata: LTS0228811
25931 - Datiscaceae: LTS0228811
26000 - Elaeocarpaceae: LTS0228811
26005 - Elaeocarpus: LTS0228811
2501685 - Elaeocarpus dolichostylus: 10.1021/NP50036A013
2501685 - Elaeocarpus dolichostylus: 10.1021/NP50039A010
2501685 - Elaeocarpus dolichostylus: LTS0228811
1526293 - Elaeocarpus mastersii: 10.1016/S0031-9422(02)00232-7
1526293 - Elaeocarpus mastersii: LTS0228811
2759 - Eukaryota: LTS0228811
213600 - Gurania: LTS0228811
627488 - Gurania subumbellata: LTS0228811
64233 - Hemsleya: LTS0228811
447114 - Hemsleya ellipsoidea: 10.1016/S0031-9422(97)00519-0
447114 - Hemsleya ellipsoidea: LTS0228811
447116 - Hemsleya gigantha: 10.1055/S-2006-962455
447116 - Hemsleya gigantha: LTS0228811
4136 - Lamiaceae: LTS0228811
3398 - Magnoliopsida: LTS0228811
23201 - Physocarpus: LTS0228811
141000 - Physocarpus capitatus: 10.1021/NP8005259
141000 - Physocarpus capitatus: LTS0228811
133202 - Physocarpus opulifolius: 10.1016/S0031-9422(98)00653-0
133202 - Physocarpus opulifolius: LTS0228811
23209 - Purshia: LTS0228811
1795987 - Purshia mexicana: LTS0228811
3745 - Rosaceae: LTS0228811
35493 - Streptophyta: LTS0228811
58023 - Tracheophyta: LTS0228811
33090 - Viridiplantae: LTS0228811

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Dong-Bao Hu, Shu-Ya Wei, Jun Yang, Dong-Dong Zhang, Xiao-Yan Duan, Hui Yan, Xing-Zhi Yang, Xue Bai, Ji-Feng Luo, Jing-Hua Yang, Yun-Song Wang, Yue-Hu Wang. Heterodimers with a cucurbitane-type triterpenoid skeleton from the branches of Elaeocarpus dubius. Phytochemistry. 2023 Mar; 207(?):113581. doi: 10.1016/j.phytochem.2022.113581. [PMID: 36592859]
Xianjing Zhang, Huihui Li, Wenqiong Wang, Tong Chen, Lijiang Xuan. Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives. Journal of natural products. 2020 12; 83(12):3536-3544. doi: 10.1021/acs.jnatprod.0c00364. [PMID: 33269591]
Jian Wang, Yang-min Ma, Meng-ru Yan, Qian Xu, Zi-rui Qu, Zhi Miao. [Chemical Compositions from Stems and Branches of Sorbaria arborea]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 Oct; 38(10):2098-101. doi: . [PMID: 27254923]
Aiko Ito, Hee-Byung Chai, Dongho Lee, Leonardus B S Kardono, Soedarsono Riswan, Norman R Farnsworth, Geoffrey A Cordell, John M Pezzuto, A Douglas Kinghorn. Ellagic acid derivatives and cytotoxic cucurbitacins from Elaeocarpus mastersii. Phytochemistry. 2002 Sep; 61(2):171-4. doi: 10.1016/s0031-9422(02)00232-7. [PMID: 12169311]
X Fang, C H Phoebe, J M Pezzuto, H H Fong, N R Farnsworth, B Yellin, S M Hecht. Plant anticancer agents, XXXIV. Cucurbitacins from Elaeocarpus dolichostylus. Journal of natural products. 1984 Nov; 47(6):988-93. doi: 10.1021/np50036a013. [PMID: 6549470]