Isobutrin (BioDeep_00000006898)

   

PANOMIX_OTCML-2023 natural product Volatile Flavor Compounds


代谢物信息卡片


(E) -3,4-Bis (beta-D-glucopyranosyloxy) -2,4-dihydroxychalcone

化学式: C27H32O15 (596.1741122)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 50%

分子结构信息

SMILES: C(=C\C(=O)c1ccc(cc1O)O[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O)/c1ccc(c(c1)O[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O)O
InChI: InChI=1S/C27H32O15/c28-9-18-20(33)22(35)24(37)26(41-18)39-12-3-4-13(16(32)8-12)14(30)5-1-11-2-6-15(31)17(7-11)40-27-25(38)23(36)21(34)19(10-29)42-27/h1-8,18-29,31-38H,9-10H2/b5-1+/t18-,19-,20-,21-,22+,23+,24-,25-,26-,27-/m1/s1

描述信息

A member of the class of chalcones that is trans-chalcone substituted by beta-D-glucopyranosyloxy groups at positions 3 and 4 and hydroxy groups at positions 4 and 2 respectively.

同义名列表

3 个代谢物同义名

Isobutrin; (E) -3,4-Bis (beta-D-glucopyranosyloxy) -2,4-dihydroxychalcone; Isobutrin



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Isabelle Krolikiewicz-Renimel, Thomas Michel, Emilie Destandau, Madhukar Reddy, Patrice André, Claire Elfakir, Chantal Pichon. Protective effect of a Butea monosperma (Lam.) Taub. flowers extract against skin inflammation: antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities. Journal of ethnopharmacology. 2013 Jul; 148(2):537-43. doi: 10.1016/j.jep.2013.05.001. [PMID: 23680157]
  • R D Sharma, A R Veerpathran, G Dakshinamoorthy, K N Sahare, K Goswami, M V R Reddy. Possible implication of oxidative stress in anti filarial effect of certain traditionally used medicinal plants in vitro against Brugia malayi microfilariae. Pharmacognosy research. 2010 Nov; 2(6):350-4. doi: 10.4103/0974-8490.75453. [PMID: 21713137]
  • R Gadekar, P K Singour, P K Chaurasiya, R S Pawar, U K Patil. A potential of some medicinal plants as an antiulcer agents. Pharmacognosy reviews. 2010 Jul; 4(8):136-46. doi: 10.4103/0973-7847.70906. [PMID: 22228953]
  • Zafar Rasheed, Nahid Akhtar, Abubakar Khan, Khursheed A Khan, Tariq M Haqqi. Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8. The Journal of pharmacology and experimental therapeutics. 2010 May; 333(2):354-63. doi: 10.1124/jpet.109.165209. [PMID: 20164300]
  • Zafar Rasheed, Nahid Akhtar, Tariq M Haqqi. Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes. Arthritis research & therapy. 2010; 12(5):R195. doi: 10.1186/ar3166. [PMID: 20955562]
  • A Sehrawat, T H Khan, L Prasad, S Sultana. Butea monosperma and chemomodulation: protective role against thioacetamide-mediated hepatic alterations in Wistar rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2006 Feb; 13(3):157-63. doi: 10.1016/j.phymed.2004.11.007. [PMID: 16428022]