P-Dichlorobenzene (BioDeep_00000006414)
Secondary id: BioDeep_00001867636
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
化学式: C6H4Cl2 (145.96900440000002)
中文名称: 1,4-二氯苯
谱图信息:
最多检出来源 Homo sapiens(blood) 0.04%
分子结构信息
SMILES: C1=CC(=CC=C1Cl)Cl
InChI: InChI=1S/C6H4Cl2/c7-5-1-2-6(8)4-3-5/h1-4H
描述信息
1,4-Dichlorobenzene (p-DCB, para-dichlorobenzene) is an organic compound with the formula C6H4Cl2. This colorless solid has a strong odor. In terms of its structure, the molecule consists of two chlorine atoms substituted for hydrogen at opposing sites on a benzene ring. p-DCB is used a pesticide and a deodorant, most familiarly in mothballs in which it is a replacement for the more traditional naphthalene. p-DCB is also used as a precursor in the production of the polymer poly(p-phenylene sulfide).
D010575 - Pesticides > D007306 - Insecticides
D009676 - Noxae > D002273 - Carcinogens
D016573 - Agrochemicals
同义名列表
46 个代谢物同义名
1,4-Dichlorobenzene (acd/name 4.0); Dichlorobenzene, p-, solid; p-Chlorophenyl chloride; Rcra waste number u072; Rcra waste number u070; Rcra waste number u071; Dichlorobenzene, para; 1,4-Dichloro-benzene; 1, 4-Dichlorobenzene; Para-dichlorobenzene; 1,4-Dichloorbenzeen; 1,4-DICHLOROBENZENE; Paradichlorobenzene; 1,4-Diclorobenzene; p-Dichloro-benzene; Paradichlorobenzol; 1,4-Dichlor-benzol; Paradichlorbenzol; P-Dichlorobenzene; p-Dichloorbenzeen; 4-Dichlorobenzene; 1,4-Chlorobenzene; p-Dichlorbenzene; p-Diclorobenzene; p-Dichlorobenzol; p-Dichlorbenzol; dichlorobenzene; Persia-perazol; Di-chloricide; Para crystals; Dichlorocide; Paranuggets; Santochlor; Paramoth; Paracide; Parazene; Paradow; Kaydox; Globol; Paradi; Evola; PDCB; PARA; PDB; 1,4-Dichlorobenzene; 1,4-Dichlorobenzene
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:28618
- KEGG: C07092
- PubChem: 4685
- HMDB: HMDB0041971
- Metlin: METLIN44571
- ChEMBL: CHEMBL190982
- Wikipedia: 1,4-Dichlorobenzene
- chemspider: 13866817
- CAS: 68890-93-7
- CAS: 55232-43-4
- CAS: 106-46-7
- PMhub: MS000019451
- PubChem: 9303
- NIKKAJI: J4.033I
- RefMet: p-Dichlorobenzene
- KNApSAcK: 28618
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- 1,4-dichlorobenzene degradation:
1,4-dichlorobenzene + H+ + NADH + O2 ⟶ (1R,2S)-3,6-dichlorocyclohexa-3,5-diene-1,2-diol + NAD+
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Toshiaki Yoshida, Mayumi Mimura, Naomi Sakon. Estimating household exposure to moth repellents p-dichlorobenzene and naphthalene and the relative contribution of inhalation pathway in a sample of Japanese children.
The Science of the total environment.
2021 Aug; 783(?):146988. doi:
10.1016/j.scitotenv.2021.146988
. [PMID: 34088142] - Joon Yau Leong, Margarita Gianniosis, Saman Zafar, Yan Zhang. Mothball ingestion as a manifestation of pica, leading to paradichlorobenzene CNS toxicity.
African health sciences.
2020 Jun; 20(2):932-935. doi:
10.4314/ahs.v20i2.48
. [PMID: 33163061] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Payal Patel, Ahmara Ross, Fredrick M Henretig, Grant Liu, Brian Harding, Jessica Panzer. Clinical Reasoning: A 12-year-old girl with headache and change in mental status.
Neurology.
2018 03; 90(11):524-529. doi:
10.1212/wnl.0000000000005116
. [PMID: 29530960] - Andries A Kampfraath, Daniel Giesen, Cornelis A M van Gestel, Cécile Le Lann. Pesticide stress on plants negatively affects parasitoid fitness through a bypass of their phytophage hosts.
Ecotoxicology (London, England).
2017 Apr; 26(3):383-395. doi:
10.1007/s10646-017-1771-x
. [PMID: 28188590] - Yudan Wei, Jianmin Zhu. Para-Dichlorobenzene Exposure Is Associated with Thyroid Dysfunction in US Adolescents.
The Journal of pediatrics.
2016 10; 177(?):238-243. doi:
10.1016/j.jpeds.2016.06.085
. [PMID: 27476635] - Zhongbing Chen, Peter Kuschk, Heidrun Paschke, Matthias Kästner, Heinz Köser. The dynamics of low-chlorinated benzenes in a pilot-scale constructed wetland and a hydroponic plant root mat treating sulfate-rich groundwater.
Environmental science and pollution research international.
2015 Mar; 22(5):3886-94. doi:
10.1007/s11356-014-3618-9
. [PMID: 25280503] - Keiyu Oshida, Naresh Vasani, Russell S Thomas, Dawn Applegate, Mitch Rosen, Barbara Abbott, Christopher Lau, Grace Guo, Lauren M Aleksunes, Curtis Klaassen, J Christopher Corton. Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium.
PloS one.
2015; 10(2):e0112655. doi:
10.1371/journal.pone.0112655
. [PMID: 25689681] - Zhentao Zhang, Alejandro Moreno. "Toilet cake" encephalopathy.
Journal of addiction medicine.
2014 Nov; 8(6):474-5. doi:
10.1097/adm.0000000000000073
. [PMID: 25187976] - Francis Buckman. Paradichlorobenzene (toxin)-induced leucoencephalopathy.
BMJ case reports.
2013 Apr; 2013(?):. doi:
10.1136/bcr-2013-009407
. [PMID: 23608871] - Claire Philippat, Marion Mortamais, Cécile Chevrier, Claire Petit, Antonia M Calafat, Xiaoyun Ye, Manori J Silva, Christian Brambilla, Isabelle Pin, Marie-Aline Charles, Sylvaine Cordier, Rémy Slama. Exposure to phthalates and phenols during pregnancy and offspring size at birth.
Environmental health perspectives.
2012 Mar; 120(3):464-70. doi:
10.1289/ehp.1103634
. [PMID: 21900077] - Angélique San Miguel, Mathieu Faure, Patrick Ravanel, Muriel Raveton. Biological responses of maize (Zea mays) plants exposed to chlorobenzenes. Case study of monochloro-, 1,4-dichloro- and 1,2,4-trichloro-benzenes.
Ecotoxicology (London, England).
2012 Mar; 21(2):315-24. doi:
10.1007/s10646-011-0792-0
. [PMID: 21947666] - Ben J Friedman, Casey A Carlos, Veronica Richardson, Misha Rosenbach. A fatal case of mothball intoxication presenting with refractory pruritus and ichthyosis.
Archives of dermatology.
2012 Mar; 148(3):404-5. doi:
10.1001/archdermatol.2011.2297
. [PMID: 22431793] - Antonius Indarto. Decomposition of dichlorobenzene in a dielectric barrier discharge.
Environmental technology.
2012 Feb; 33(4-6):663-6. doi:
10.1080/09593330.2011.587026
. [PMID: 22629641] - Jing Wu, Chao-bo Xie, Zhi-ping Cao, Ya-nan Sun, Xi Xiang, Chun-yan Dai. [Fluorescence fingerprint properties of refinery wastewater].
Guang pu xue yu guang pu fen xi = Guang pu.
2012 Feb; 32(2):415-9. doi:
"
. [PMID: 22512181] - Wei Fu, Xiaojun Ma, Qi Tang, Changming Mo. Karyotype analysis and genetic variation of a mutant in Siraitia grosvenorii.
Molecular biology reports.
2012 Feb; 39(2):1247-52. doi:
10.1007/s11033-011-0855-6
. [PMID: 21603854] - Clemencia Rodriguez, Kathryn Linge, Palenque Blair, Francesco Busetti, Brian Devine, Paul Van Buynder, Philip Weinstein, Angus Cook. Recycled water: potential health risks from volatile organic compounds and use of 1,4-dichlorobenzene as treatment performance indicator.
Water research.
2012 Jan; 46(1):93-106. doi:
10.1016/j.watres.2011.10.032
. [PMID: 22078226] - Ingrid Elisia, David D Kitts. Quantification of hexanal as an index of lipid oxidation in human milk and association with antioxidant components.
Journal of clinical biochemistry and nutrition.
2011 Nov; 49(3):147-52. doi:
10.3164/jcbn.10-142
. [PMID: 22128211] - Lourdes Fernandez-Calvino, Christine Faulkner, John Walshaw, Gerhard Saalbach, Emmanuelle Bayer, Yoselin Benitez-Alfonso, Andrew Maule. Arabidopsis plasmodesmal proteome.
PloS one.
2011 Apr; 6(4):e18880. doi:
10.1371/journal.pone.0018880
. [PMID: 21533090] - Kanako Watanabe, Hiroki Fujita, Koutaro Hasegawa, Kunio Gonmori, Osamu Suzuki. GC/MS with post-column switching for large volume injection of headspace samples: sensitive determination of volatile organic compounds in human whole blood and urine.
Analytical chemistry.
2011 Feb; 83(4):1475-9. doi:
10.1021/ac1026258
. [PMID: 21268608] - Päivi L H Rinne, Annikki Welling, Jorma Vahala, Linda Ripel, Raili Ruonala, Jaakko Kangasjärvi, Christiaan van der Schoot. Chilling of dormant buds hyperinduces FLOWERING LOCUS T and recruits GA-inducible 1,3-beta-glucanases to reopen signal conduits and release dormancy in Populus.
The Plant cell.
2011 Jan; 23(1):130-46. doi:
10.1105/tpc.110.081307
. [PMID: 21282527] - Corey M Hudson, Emily E Puckett, Michaël Bekaert, J Chris Pires, Gavin C Conant. Selection for higher gene copy number after different types of plant gene duplications.
Genome biology and evolution.
2011; 3(?):1369-80. doi:
10.1093/gbe/evr115
. [PMID: 22056313] - Federico Brilli, Taina M Ruuskanen, Ralf Schnitzhofer, Markus Müller, Martin Breitenlechner, Vinzenz Bittner, Georg Wohlfahrt, Francesco Loreto, Armin Hansel. Detection of plant volatiles after leaf wounding and darkening by proton transfer reaction 'time-of-flight' mass spectrometry (PTR-TOF).
PloS one.
2011; 6(5):e20419. doi:
10.1371/journal.pone.0020419
. [PMID: 21637822] - E-E Chang, Wang Wei-Chi, Zeng Li-Xuan, Chiang Hung-Lung. Health risk assessment of exposure to selected volatile organic compounds emitted from an integrated iron and steel plant.
Inhalation toxicology.
2010 Dec; 22 Suppl 2(?):117-25. doi:
10.3109/08958378.2010.507636
. [PMID: 20828338] - Muchtaridi, Anas Subarnas, Anton Apriyantono, Resmi Mustarichie. Identification of compounds in the essential oil of nutmeg seeds (Myristica fragrans Houtt.) that inhibit locomotor activity in mice.
International journal of molecular sciences.
2010 Nov; 11(11):4771-81. doi:
10.3390/ijms11114771
. [PMID: 21151471] - Shoko Ueki, Roman Spektor, Danielle M Natale, Vitaly Citovsky. ANK, a host cytoplasmic receptor for the Tobacco mosaic virus cell-to-cell movement protein, facilitates intercellular transport through plasmodesmata.
PLoS pathogens.
2010 Nov; 6(11):e1001201. doi:
10.1371/journal.ppat.1001201
. [PMID: 21124937] - Wang Suhua, Lu Rongzhu, Yin Changqing, Xing Guangwei, Han Fangan, Jing Junjie, Xu Wenrong, Michael Aschner. Lipid peroxidation and changes of trace elements in mice treated with paradichlorobenzene.
Biological trace element research.
2010 Sep; 136(3):320-36. doi:
10.1007/s12011-009-8552-1
. [PMID: 19888557] - Mary S Wolff, Susan L Teitelbaum, Susan M Pinney, Gayle Windham, Laura Liao, Frank Biro, Lawrence H Kushi, Chris Erdmann, Robert A Hiatt, Michael E Rybak, Antonia M Calafat. Investigation of relationships between urinary biomarkers of phytoestrogens, phthalates, and phenols and pubertal stages in girls.
Environmental health perspectives.
2010 Jul; 118(7):1039-46. doi:
10.1289/ehp.0901690
. [PMID: 20308033] - Stephanie H Hernandez, Sage W Wiener, Silas W Smith. Case files of the New York City poison control center: paradichlorobenzene-induced leukoencephalopathy.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2010 Jun; 6(2):217-29. doi:
10.1007/s13181-010-0053-2
. [PMID: 20373064] - Rosemary Castorina, Asa Bradman, Laura Fenster, Dana Boyd Barr, Roberto Bravo, Michelle G Vedar, Martha E Harnly, Thomas E McKone, Ellen A Eisen, Brenda Eskenazi. Comparison of current-use pesticide and other toxicant urinary metabolite levels among pregnant women in the CHAMACOS cohort and NHANES.
Environmental health perspectives.
2010 Jun; 118(6):856-63. doi:
10.1289/ehp.0901568
. [PMID: 20129873] - Tracey Ruhlman, Dheeraj Verma, Nalapalli Samson, Henry Daniell. The role of heterologous chloroplast sequence elements in transgene integration and expression.
Plant physiology.
2010 Apr; 152(4):2088-104. doi:
10.1104/pp.109.152017
. [PMID: 20130101] - Gayathri D Warnasuriya, Barbara M Elcombe, John R Foster, Clifford R Elcombe. A Mechanism for the induction of renal tumours in male Fischer 344 rats by short-chain chlorinated paraffins.
Archives of toxicology.
2010 Mar; 84(3):233-43. doi:
10.1007/s00204-009-0489-9
. [PMID: 20069279] - Lena Burri, G Hege Thoresen, Rolf K Berge. The Role of PPARα Activation in Liver and Muscle.
PPAR research.
2010; 2010(?):. doi:
10.1155/2010/542359
. [PMID: 20847941] - Kanako Watanabe, Koutaro Hasegawa, Itaru Yamagishi, Hideki Nozawa, Masamitsu Takaba, Osamu Suzuki. Simple isotope dilution headspace-GC-MS analysis of naphthalene and p-dichlorobenzene in whole blood and urine.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2009 Nov; 25(11):1301-5. doi:
10.2116/analsci.25.1301
. [PMID: 19907086] - Pao-Kuei Hsiao, Yi-Chang Lin, Tung-Sheng Shih, Yin-Mei Chiung. Effects of occupational exposure to 1,4-dichlorobenzene on hematologic, kidney, and liver functions.
International archives of occupational and environmental health.
2009 Oct; 82(9):1077-85. doi:
10.1007/s00420-009-0398-5
. [PMID: 19247685] - Larry B Barber, Steffanie H Keefe, Denis R Leblanc, Paul M Bradley, Francis H Chapelle, Michael T Meyer, Keith A Loftin, Dana W Kolpin, Fernando Rubio. Fate of sulfamethoxazole, 4-nonylphenol, and 17beta-estradiol in groundwater contaminated by wastewater treatment plant effluent.
Environmental science & technology.
2009 Jul; 43(13):4843-50. doi:
10.1021/es803292v
. [PMID: 19673274] - Jing Liu, Wanzer Drane, Xuefeng Liu, Tiejian Wu. Examination of the relationships between environmental exposures to volatile organic compounds and biochemical liver tests: application of canonical correlation analysis.
Environmental research.
2009 Feb; 109(2):193-9. doi:
10.1016/j.envres.2008.11.002
. [PMID: 19117555] - Xingmao Ma, Megan M Havelka. Phytotoxicity of chlorinated benzenes to Typha angustifolia and Phragmites communis.
Environmental toxicology.
2009 Feb; 24(1):43-8. doi:
10.1002/tox.20393
. [PMID: 18442064] - P-C Harizanis, E Alissandrakis, P-A Tarantilis, M Polissiou. Solid-phase microextraction/gas-chromatographic/mass spectrometric analysis of p-dichlorobenzene and naphthalene in honey.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2008 Oct; 25(10):1272-7. doi:
10.1080/02652030802007546
. [PMID: 18608488] - Mary S Wolff, Stephanie M Engel, Gertrud S Berkowitz, Xiaoyun Ye, Manori J Silva, Chenbo Zhu, James Wetmur, Antonia M Calafat. Prenatal phenol and phthalate exposures and birth outcomes.
Environmental health perspectives.
2008 Aug; 116(8):1092-7. doi:
10.1289/ehp.11007
. [PMID: 18709157] - Y S Lin, P P Egeghy, S M Rappaport. Relationships between levels of volatile organic compounds in air and blood from the general population.
Journal of exposure science & environmental epidemiology.
2008 Jul; 18(4):421-9. doi:
10.1038/sj.jes.7500635
. [PMID: 18059425] - Kyung-Bum Lee, Philippe De Backer, Toshihiro Aono, Chi-Te Liu, Shino Suzuki, Tadahiro Suzuki, Takakazu Kaneko, Manabu Yamada, Satoshi Tabata, Doris M Kupfer, Fares Z Najar, Graham B Wiley, Bruce Roe, Tim T Binnewies, David W Ussery, Wim D'Haeze, Jeroen Den Herder, Dirk Gevers, Danny Vereecke, Marcelle Holsters, Hiroshi Oyaizu. The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.
BMC genomics.
2008 Jun; 9(?):271. doi:
10.1186/1471-2164-9-271
. [PMID: 18522759] - Magdalena V Monferran, Silvia F Pesce, Jimena Cazenave, Daniel A Wunderlin. Detoxification and antioxidant responses in diverse organs of Jenynsia multidentata experimentally exposed to 1,2- and 1,4-dichlorobenzene.
Environmental toxicology.
2008 Apr; 23(2):184-92. doi:
10.1002/tox.20326
. [PMID: 18214911] - Mehmet Cindoruk, Mustafa Kerem, Tarkan Karakan, Bulent Salman, Okan Akin, Murat Alper, Ozlem Erdem, Selahattin Unal. Peroxisome proliferators-activated alpha agonist treatment ameliorates hepatic damage in rats with obstructive jaundice: an experimental study.
BMC gastroenterology.
2007 Nov; 7(?):44. doi:
10.1186/1471-230x-7-44
. [PMID: 18045488] - Magdalena V Monferran, Daniel A Wunderlin, Jorge Nimptsch, Stephan Pflugmacher. Biotransformation and antioxidant response in Ceratophyllum demersum experimentally exposed to 1,2- and 1,4-dichlorobenzene.
Chemosphere.
2007 Aug; 68(11):2073-9. doi:
10.1016/j.chemosphere.2007.02.016
. [PMID: 17368727] - Bing-Ling Wang, Tomoko Takigawa, Akito Takeuchi, Yukie Yamasaki, Hiroyuki Kataoka, Da-Hong Wang, Keiki Ogino. Unmetabolized VOCs in urine as biomarkers of low level exposure in indoor environments.
Journal of occupational health.
2007 Mar; 49(2):104-10. doi:
10.1539/joh.49.104
. [PMID: 17429167] - Shiau-Chian Soh, Md Pauzi Abdullah. Determination of volatile organic compounds pollution sources in malaysian drinking water using multivariate analysis.
Environmental monitoring and assessment.
2007 Jan; 124(1-3):39-50. doi:
10.1007/s10661-006-9207-8
. [PMID: 16967208] - Raymond Cheong, Robin K Wilson, Irene C M Cortese, David E Newman-Toker. Mothball withdrawal encephalopathy: case report and review of paradichlorobenzene neurotoxicity.
Substance abuse.
2006 Dec; 27(4):63-7. doi:
10.1300/j465v27n04_08
. [PMID: 17347127] - Edward Avila, Paul Schraeder, Ajit Belliappa, Scott Faro. Pica with paradichlorobenzene mothball ingestion associated with toxic leukoencephalopathy.
Journal of neuroimaging : official journal of the American Society of Neuroimaging.
2006 Jan; 16(1):78-81. doi:
10.1177/1051228405280171
. [PMID: 16483281] - Shigetoshi Aiso, Tetsuya Takeuchi, Heihachiro Arito, Kasuke Nagano, Seigo Yamamoto, Taijiro Matsushima. Carcinogenicity and chronic toxicity in mice and rats exposed by inhalation to para-dichlorobenzene for two years.
The Journal of veterinary medical science.
2005 Oct; 67(10):1019-29. doi:
10.1292/jvms.67.1019
. [PMID: 16276058] - Jianying Zhang, Wei Zhao, Jun Pan, Limin Qiu, Yinmei Zhu. Tissue-dependent distribution and accumulation of chlorobenzenes by vegetables in urban area.
Environment international.
2005 Aug; 31(6):855-60. doi:
10.1016/j.envint.2005.05.034
. [PMID: 16002141] - Shigetoshi Aiso, Heihachiro Arito, Tomoshi Nishizawa, Kasuke Nagano, Seigo Yamamoto, Taijiro Matsushima. Thirteen-week inhalation toxicity of p-dichlorobenzene in mice and rats.
Journal of occupational health.
2005 May; 47(3):249-60. doi:
10.1539/joh.47.249
. [PMID: 15953847] - Lee C Garratt, Robert Linforth, Andrew J Taylor, Kenneth C Lowe, J Brian Power, Michael R Davey. Metabolite fingerprinting in transgenic lettuce.
Plant biotechnology journal.
2005 Mar; 3(2):165-74. doi:
10.1111/j.1467-7652.2004.00110.x
. [PMID: 17173617] - Yu Qian, Daqiang Yin, Yan Li, Jun Wang, Min Zhang, Shuangqing Hu. Effects of four chlorobenzenes on serum sex steroids and hepatic microsome enzyme activities in crucian carp, Carassius auratus.
Chemosphere.
2004 Oct; 57(2):127-33. doi:
10.1016/j.chemosphere.2004.04.044
. [PMID: 15294436] - Cris L Lewis, Mathew A Moser, Don E Dale, Wei Hang, Christian Hassell, Fred L King, Vahid Majidi. Time-gated pulsed glow discharge: real-time chemical speciation at the elemental, structural, and molecular level for gas chromatography time-of-flight mass spectrometry.
Analytical chemistry.
2003 05; 75(9):1983-96. doi:
10.1021/ac026242u
. [PMID: 12720331] - Bram J Versonnen, Katrien Arijs, Tim Verslycke, Wouter Lema, Colin R Janssen. In vitro and in vivo estrogenicity and toxicity of o-, m-, and p-dichlorobenzene.
Environmental toxicology and chemistry.
2003 Feb; 22(2):329-35. doi:
NULL
. [PMID: 12558164] - Angela Mally, James Kevin Chipman. Non-genotoxic carcinogens: early effects on gap junctions, cell proliferation and apoptosis in the rat.
Toxicology.
2002 Dec; 180(3):233-48. doi:
10.1016/s0300-483x(02)00393-1
. [PMID: 12393293] - T Yoshida, K Andoh, M Fukuhara. Urinary 2,5-dichlorophenol as biological index for p-dichlorobenzene exposure in the general population.
Archives of environmental contamination and toxicology.
2002 Nov; 43(4):481-5. doi:
10.1007/s00244-002-1228-x
. [PMID: 12399920] - Toshiaki Yoshida, Katashi Andoh, Hiroshi Kosaka, Shinji Kumagai, Ichiro Matsunaga, Susumu Akasaka, Sei-ichi Nakamura, Hajime Oda, Morio Fukuhara. Inhalation toxicokinetics of p-dichlorobenzene and daily absorption and internal accumulation in chronic low-level exposure to humans.
Archives of toxicology.
2002 Jun; 76(5-6):306-15. doi:
10.1007/s00204-002-0341-y
. [PMID: 12107648] - Clifford R Elcombe, Jenny Odum, John R Foster, Susan Stone, Susan Hasmall, Anthony R Soames, Ian Kimber, John Ashby. Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.
Environmental health perspectives.
2002 Apr; 110(4):363-75. doi:
10.1289/ehp.02110363
. [PMID: 11940454] - Zhiming Yang, Yanlin Li, Huiqi Xie, Tingwu Qin, Fuguo Huang. [Experimental studies on histocompatibility of three bio-derived bones].
Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery.
2002 Jan; 18(1):6-8. doi:
NULL
. [PMID: 11977625] - S P Cooper, K Burau, A Sweeney, T Robison, M A Smith, E Symanski, J S Colt, J Laseter, S H Zahm. Prenatal exposure to pesticides: a feasibility study among migrant and seasonal farmworkers.
American journal of industrial medicine.
2001 Nov; 40(5):578-85. doi:
10.1002/ajim.1123
. [PMID: 11675627] - M S McCabe, L C Garratt, F Schepers, W J Jordi, G M Stoopen, E Davelaar, J H van Rhijn, J B Power, M R Davey. Effects of P(SAG12)-IPT gene expression on development and senescence in transgenic lettuce.
Plant physiology.
2001 Oct; 127(2):505-16. doi:
10.1104/pp.010244
. [PMID: 11598225] - T Umemura, Y Kodama, Y Kurokawa, G M Williams. Lack of oxidative DNA damage or initiation of carcinogenesis in the kidneys of male F344 rats given subchronic exposure to p-dichlorobenzene (pDCB) at a carcinogenic dose.
Archives of toxicology.
2000 Mar; 74(1):54-9. doi:
10.1007/s002040050652
. [PMID: 10817668] - L Robbiano, R Carrozzino, C P Puglia, C Corbu, G Brambilla. Correlation between induction of DNA fragmentation and micronuclei formation in kidney cells from rats and humans and tissue-specific carcinogenic activity.
Toxicology and applied pharmacology.
1999 Dec; 161(2):153-9. doi:
10.1006/taap.1999.8796
. [PMID: 10581209] - J A Barter, J H Sherman. An evaluation of the carcinogenic hazard of 1,4-dichlorobenzene based on internationally recognized criteria.
Regulatory toxicology and pharmacology : RTP.
1999 Feb; 29(1):64-79. doi:
10.1006/rtph.1998.1269
. [PMID: 10051419] - X Yin, Y Qin, Y Guo, L Zhang. [Study on toxicity of P-Dichlorobenzene].
Wei sheng yan jiu = Journal of hygiene research.
1998 Nov; 27(6):377-8. doi:
. [PMID: 11939021]
- E M Bomhard, U Schmidt, E Löser. Time course of enzyme induction in liver and kidneys and absorption, distribution and elimination of 1,4-dichlorobenzene in rats.
Toxicology.
1998 Nov; 131(2-3):73-91. doi:
10.1016/s0300-483x(98)00107-3
. [PMID: 9928623] - T Umemura, K Takada, C Schulz, R Gebhardt, Y Kurokawa, G M Williams. Cell proliferation in the livers of male mice and rats exposed to the carcinogen P-dichlorobenzene: evidence for thresholds.
Drug and chemical toxicology.
1998 Feb; 21(1):57-66. doi:
10.3109/01480549809017851
. [PMID: 9530531] - J H Sherman, R S Nair, K L Steinmetz, J C Mirsalis, E R Nestmann, J A Barter. Evaluation of unscheduled DNA synthesis (UDS) and replicative DNA synthesis (RDS) following treatment of rats and mice with p-dichlorobenzene.
Teratogenesis, carcinogenesis, and mutagenesis.
1998; 18(6):309-18. doi:
10.1002/(sici)1520-6866(1998)18:6<309::aid-tcm5>3.0.co;2-p
. [PMID: 10052566] - B G Lake, M E Cunninghame, R J Price. Comparison of the hepatic and renal effects of 1,4-dichlorobenzene in the rat and mouse.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1997 Sep; 39(1):67-75. doi:
10.1006/faat.1997.2350
. [PMID: 9325029] - Y F Sasaki, F Izumiyama, E Nishidate, N Matsusaka, S Tsuda. Detection of rodent liver carcinogen genotoxicity by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow).
Mutation research.
1997 Jul; 391(3):201-14. doi:
10.1016/s1383-5718(97)00072-7
. [PMID: 9268046] - A M Hissink, R Dunnewijk, B van Ommen, P J van Bladeren. Kinetics and metabolism of 1,4-dichlorobenzene in male Wistar rats: no evidence for quinone metabolites.
Chemico-biological interactions.
1997 Jan; 103(1):17-33. doi:
10.1016/s0009-2797(96)03746-5
. [PMID: 9051121] - T Umemura, M Saito, A Takagi, Y Kurokawa. Isomer-specific acute toxicity and cell proliferation in livers of B6C3F1 mice exposed to dichlorobenzene.
Toxicology and applied pharmacology.
1996 Apr; 137(2):268-74. doi:
10.1006/taap.1996.0080
. [PMID: 8661352] - R H Hill, D L Ashley, S L Head, L L Needham, J L Pirkle. p-Dichlorobenzene exposure among 1,000 adults in the United States.
Archives of environmental health.
1995 Jul; 50(4):277-80. doi:
10.1080/00039896.1995.9935954
. [PMID: 7677426] - T Mizutani, Y Nakahori, K Yamamoto. p-Dichlorobenzene-induced hepatotoxicity in mice depleted of glutathione by treatment with buthionine sulfoximine.
Toxicology.
1994 Nov; 94(1-3):57-67. doi:
10.1016/0300-483x(94)90028-0
. [PMID: 7801330] - C Klos, W Dekant. Comparative metabolism of the renal carcinogen 1,4-dichlorobenzene in rat: identification and quantitation of novel metabolites.
Xenobiotica; the fate of foreign compounds in biological systems.
1994 Oct; 24(10):965-76. doi:
10.3109/00498259409043294
. [PMID: 7900412] - M A Valentovic, J G Ball, D Anestis, E Madan. Acute hepatic and renal toxicity of dichlorobenzene isomers in Fischer 344 rats.
Journal of applied toxicology : JAT.
1993 Jan; 13(1):1-7. doi:
10.1002/jat.2550130103
. [PMID: 8440869] - R L Fisher, A J Gandolfi, I G Sipes, K Brendel. Culture medium composition affects the relative toxicities of chlorobenzenes in rat liver slices and the isolated perfused liver.
Drug and chemical toxicology.
1993; 16(4):321-39. doi:
10.3109/01480549308998224
. [PMID: 8281887] - K Saito, H Kaneko, N Isobe, I Nakatsuka, A Yoshitake, H Yamada. Differences in alpha 2u-globulins increased in male rat kidneys following treatment with several alpha 2u-globulin accumulating agents: cystein protease(s) play(s) an important role in production of kidney-type-alpha 2u-globulin.
Toxicology.
1992 Nov; 76(2):177-86. doi:
10.1016/0300-483x(92)90163-9
. [PMID: 1281346] - S R Eldridge, T L Goldsworthy, J A Popp, B E Butterworth. Mitogenic stimulation of hepatocellular proliferation in rodents following 1,4-dichlorobenzene administration.
Carcinogenesis.
1992 Mar; 13(3):409-15. doi:
10.1093/carcin/13.3.409
. [PMID: 1547531] - C den Besten, J J Vet, H T Besselink, G S Kiel, B J van Berkel, R Beems, P J van Bladeren. The liver, kidney, and thyroid toxicity of chlorinated benzenes.
Toxicology and applied pharmacology.
1991 Oct; 111(1):69-81. doi:
10.1016/0041-008x(91)90135-2
. [PMID: 1949037] - P L McCarty. Terrestrial physical and chemical processes for liquid waste treatment.
Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA.
1991 Oct; 9(5):379-87. doi:
10.1177/0734242x9100900155
. [PMID: 11537689] - E R Stine, L Gunawardhana, I G Sipes. The acute hepatotoxicity of the isomers of dichlorobenzene in Fischer-344 and Sprague-Dawley rats: isomer-specific and strain-specific differential toxicity.
Toxicology and applied pharmacology.
1991 Jul; 109(3):472-81. doi:
10.1016/0041-008x(91)90010-c
. [PMID: 1853346] - D R Dietrich, J A Swenberg. NCI-Black-Reiter (NBR) male rats fail to develop renal disease following exposure to agents that induce alpha-2u-globulin (alpha 2u) nephropathy.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1991 May; 16(4):749-62. doi:
10.1016/0272-0590(91)90161-v
. [PMID: 1715830] - S R Eldridge, L F Tilbury, T L Goldsworthy, B E Butterworth. Measurement of chemically induced cell proliferation in rodent liver and kidney: a comparison of 5-bromo-2'-deoxyuridine and [3H]thymidine administered by injection or osmotic pump.
Carcinogenesis.
1990 Dec; 11(12):2245-51. doi:
10.1093/carcin/11.12.2245
. [PMID: 2265476] - T Umemura, K Takada, Y Ogawa, E Kamata, M Saito, Y Kurokawa. Sex difference in inhalation toxicity of p-dichlorobenzene (p-DCB) in rats.
Toxicology letters.
1990 Jul; 52(2):209-14. doi:
10.1016/0378-4274(90)90155-f
. [PMID: 2378004] - T Umemura, K Takada, Y Nakaji, Y Ogawa, E Kamata, T Kaneko, M Tobe, Y Kurokawa. Comparison of the toxicity of p-dichlorobenzene (p-DCB) administered to male F344 rats orally or by the inhalation route.
The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku.
1989 Dec; 36(1-4):1-9. doi:
NULL
. [PMID: 2640063] - G Lattanzi, S Bartoli, B Bonora, A Colacci, S Grilli, A Niero, M Mazzullo. The different genotoxicity of p-dichlorobenzene in mouse and rat: measurement of the in vivo and in vitro covalent interaction with nucleic acids.
Tumori.
1989 Aug; 75(4):305-10. doi:
10.1177/030089168907500403
. [PMID: 2479159] - M Charbonneau, J Strasser, E A Lock, M J Turner, J A Swenberg. Involvement of reversible binding to alpha 2u-globulin in 1,4-dichlorobenzene-induced nephrotoxicity.
Toxicology and applied pharmacology.
1989 Jun; 99(1):122-32. doi:
10.1016/0041-008x(89)90117-8
. [PMID: 2471290] - E Bomhard, G Luckhaus, W H Voigt, E Loeser. Induction of light hydrocarbon nephropathy by p-dichlorobenzene.
Archives of toxicology.
1988; 61(6):433-9. doi:
10.1007/bf00293688
. [PMID: 2903729] - . NTP Toxicology and Carcinogenesis Studies of 1,4-Dichlorobenzene (CAS No. 106-46-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
National Toxicology Program technical report series.
1987 Jan; 319(?):1-198. doi:
. [PMID: 12748734]
- S Ghittori, M Imbriani, G Pezzagno, E Capodaglio. Urinary elimination of p-dichlorobenzene (p-DCB) and weighted exposure concentration.
Giornale italiano di medicina del lavoro.
1985 Mar; 7(2-3):59-63. doi:
NULL
. [PMID: 3836909] - P Ade, M G Banchelli Soldaini, M G Castelli, E Chiesara, F Clementi, R Fanelli, E Funari, G Ignesti, A Marabini, M Orunesu. Biochemical and morphological comparison of microsomal preparations from rat, quail, trout, mussel, and water flea.
Ecotoxicology and environmental safety.
1984 Oct; 8(5):423-46. doi:
10.1016/0147-6513(84)90064-2
. [PMID: 6489239] - E Loeser, M H Litchfield. Review of recent toxicology studies on p-dichlorobenzene.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1983 Dec; 21(6):825-32. doi:
10.1016/0278-6915(83)90219-3
. [PMID: 6363233] - S Galassi, D Calamari, F Setti. Uptake and release of p-dichlorobenzene in early life stages of Salmo gairdneri.
Ecotoxicology and environmental safety.
1982 Oct; 6(5):439-47. doi:
10.1016/0147-6513(82)90024-0
. [PMID: 6892015] - D R Hawkins, L F Chasseaud, R N Woodhouse, D G Cresswell. The distribution excretion and biotransformation of p-dichloro[14C]benzene in rats after repeated inhalation, oral and subcutaneous doses.
Xenobiotica; the fate of foreign compounds in biological systems.
1980 Feb; 10(2):81-95. doi:
10.3109/00498258009033734
. [PMID: 7395268] - S TOTARO, G LICARI. [SERUM TRANSAMINASES IN SUBACUTE EXPERIMENTAL POISONING BY PARADICHLOROBENZENE. INFLUENCE OF SOME LIPOTROPIC FACTORS].
Folia medica. Folia medica (Naples, Italy).
1964 May; 47(?):507-11. doi:
NULL
. [PMID: 14191342] - S TOTARO. [Serum transaminases and aldolases in subacute experimental poisoning by means of paradichlorobenzene].
Folia medica. Folia medica (Naples, Italy).
1961 Jul; 44(?):586-94. doi:
NULL
. [PMID: 13777657]