ST 23:5;O6 (BioDeep_00000637528)
Main id: BioDeep_00000006676
PANOMIX_OTCML-2023
代谢物信息卡片
17alpha,21-dihydroxypregn-4-ene-3,11,20-trione acetate
化学式: C23H30O6 (402.2042)
中文名称: 醋酸可的松
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)CCC34C)C)O
InChI: InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1
描述信息
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
D000893 - Anti-Inflammatory Agents
Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4].
同义名列表
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:3897
- KEGG: C90609
- KEGG: C08173
- PubChem: 5745
- DrugBank: DB01380
- ChEMBL: CHEMBL1650
- LipidMAPS: LMST02030120
- MeSH: Cortisone
- CAS: 50-04-4
- PubChem: 10373
- 3DMET: B02150
- NIKKAJI: J2.792H
- RefMet: ST 23:5;O6
- medchemexpress: HY-17461A
- KNApSAcK: 3897
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Miwa Suzuki, Noriko Funasaka, Yuki Sato, Daiki Inamori, Yurie Watanabe, Miki Ozaki, Masayuki Hosono, Hideaki Shindo, Keiko Kawamura, Toshiyuki Tatsukawa, Motoi Yoshioka. Association of seasonal changes in circulating cortisol concentrations with the expression of cortisol biosynthetic enzymes and a glucocorticoid receptor in the blubber of common bottlenose dolphin.
General and comparative endocrinology.
2024 Jun; 352(?):114516. doi:
10.1016/j.ygcen.2024.114516. [PMID: 38593942] - Chang Gao, Jiafeng Fu, Junyi Cui, Tingzhi Zhang, Christos C Zouboulis, Jing Wang, Shaowei Yan. Effects and Stress-Relieving Mechanisms of Dark Tea Polysaccharide in Human HaCaT Keratinocytes and SZ95 Sebocytes.
Molecules (Basel, Switzerland).
2023 Aug; 28(16):. doi:
10.3390/molecules28166128. [PMID: 37630380] - Camille Pouchieu, Line Pourtau, Julie Brossaud, David Gaudout, Jean-Benoit Corcuff, Lucile Capuron, Nathalie Castanon, Pierre Philip. Acute Effect of a Saffron Extract (Safr'InsideTM) and Its Main Volatile Compound on the Stress Response in Healthy Young Men: A Randomized, Double Blind, Placebo-Controlled, Crossover Study.
Nutrients.
2023 Jun; 15(13):. doi:
10.3390/nu15132921. [PMID: 37447245] - Rakesh Kumar Mishra, Anas Ahmad, Ajay Kumar, Aneesh Ali, Kanika, Chandrashekhar Jori, Shams Tabrez, Torki A Zughaibi, Majed N Almashjary, Syed Shadab Raza, Rehan Khan. Cortisone-loaded stearoyl ascorbic acid based nanostructured lipid carriers alleviate inflammatory changes in DSS-induced colitis.
Biomaterials advances.
2023 May; 148(?):213383. doi:
10.1016/j.bioadv.2023.213383. [PMID: 36958119] - Yan Wu, Jianan Ma, Jinghui Shi, Shuting Cao, Jianmei Luo, Tingting Zheng, Min Wang. iTRAQ-Based Quantitative Proteomic Analysis of Arthrobacter simplex in Response to Cortisone Acetate and Its Mutants with Improved Δ1-Dehydrogenation Efficiency.
Journal of agricultural and food chemistry.
2023 Apr; 71(16):6376-6388. doi:
10.1021/acs.jafc.3c00417. [PMID: 37043686] - Fasih Ullah Haider, Xiukang Wang, Usman Zulfiqar, Muhammad Farooq, Saddam Hussain, Tariq Mehmood, Muhammad Naveed, Yuelin Li, Cai Liqun, Qudsia Saeed, Ishtiaq Ahmad, Adnan Mustafa. Biochar application for remediation of organic toxic pollutants in contaminated soils; An update.
Ecotoxicology and environmental safety.
2022 Dec; 248(?):114322. doi:
10.1016/j.ecoenv.2022.114322. [PMID: 36455351] - Kathy Tou, Adam Cawley, Christopher Bowen, Kireesan Sornalingam, Shanlin Fu. Measurements of hydrocortisone and cortisone for longitudinal profiling of equine plasma by liquid chromatography-tandem mass spectrometry.
Drug testing and analysis.
2022 May; 14(5):943-952. doi:
10.1002/dta.3244. [PMID: 35195373] - Tuba Seven Menevse, Yasemin Kendir Demirkol, Busra Gurpinar Tosun, Elvan Bayramoglu, Melek Yildiz, Sezer Acar, Seda Erisen Karaca, Zerrin Orbak, Asan Onder, Elif Sobu, Ahmet Anık, Zeynep Atay, Fuat Bugrul, Ayse Derya Bulus, Korcan Demir, Durmus Dogan, Hamdi Cihan Emeksiz, Heves Kirmizibekmez, Nurhan Ozcan Murat, Akan Yaman, Serap Turan, Abdullah Bereket, Tulay Guran. Steroid Hormone Profiles and Molecular Diagnostic Tools in Pediatric Patients With non-CAH Primary Adrenal Insufficiency.
The Journal of clinical endocrinology and metabolism.
2022 04; 107(5):e1924-e1931. doi:
10.1210/clinem/dgac016. [PMID: 35028661] - Yu Song, Luting Nie, Dandan Wei, Pengling Liu, Keliang Fan, Li Zhang, Mian Wang, Lulu Wang, Wei Liao, Ning Kang, Qingqing Xu, Juan Wang, Zhenxing Mao, Chongjian Wang, Wenqian Huo. Serum cortisol-to-cortisone ratio and 11-deoxycortisol are associated with hypertension and blood pressure in Chinese rural population: a cross sectional study.
Journal of hypertension.
2022 03; 40(3):432-440. doi:
10.1097/hjh.0000000000003028. [PMID: 34670995] - Lisanne Rieker, Johannes Hofer, Golo Petzold, Volker Ellenrieder, Ahmad Amanzada. Induction of remission with tacrolimus in a patient with severe acute, cortisone refractory ulcerative colitis and severe Covid-19 pneumonia: a case report.
BMC gastroenterology.
2022 Jan; 22(1):22. doi:
10.1186/s12876-022-02094-3. [PMID: 35033015] - Wang Lijing, Ke Sujie, Wang Linxi, Huang Lishan, Qi Liqin, Zhan Zhidong, Wu Kejun, Zhang Mengjun, Liu Xiaoying, Liu Xiaohong, Liu Libin. Altered Caffeine Metabolism Is Associated With Recurrent Hypoglycemia in Type 2 Diabetes Mellitus: A UPLC-MS-Based Untargeted Metabolomics Study.
Frontiers in endocrinology.
2022; 13(?):843556. doi:
10.3389/fendo.2022.843556. [PMID: 35784552] - Soraya Puglisi, Marta Leporati, Eleonora Amante, Alice Parisi, Anna Rosa Pia, Paola Berchialla, Massimo Terzolo, Marco Vincenti, Giuseppe Reimondo. Limited Role of Hair Cortisol and Cortisone Measurement for Detecting Cortisol Autonomy in Patients With Adrenal Incidentalomas.
Frontiers in endocrinology.
2022; 13(?):833514. doi:
10.3389/fendo.2022.833514. [PMID: 35222288] - Lixia Zhang, Xueyuan Li, Chong Li, Zhifang Wang, Lili Zheng, Guijun Qin, Shoujun Wang, Lijun Xu. Analysis of the Clinical Characteristics and Pituitary Function of Patients in Central China With Rathke's Cleft Cysts.
Frontiers in endocrinology.
2022; 13(?):800135. doi:
10.3389/fendo.2022.800135. [PMID: 35295993] - Valentina Morelli, Sofia Frigerio, Carmen Aresta, Elena Passeri, Flavia Pugliese, Massimilano Copetti, Anna Maria Barbieri, Silvia Fustinoni, Elisa Polledri, Sabrina Corbetta, Maura Arosio, Alfredo Scillitani, Iacopo Chiodini. Adrenalectomy Improves Blood Pressure and Metabolic Control in Patients With Possible Autonomous Cortisol Secretion: Results of a RCT.
Frontiers in endocrinology.
2022; 13(?):898084. doi:
10.3389/fendo.2022.898084. [PMID: 35721734] - Annet Vulto, Martijn van Faassen, Michiel N Kerstens, André P van Beek. Susceptibility to Adrenal Crisis Is Associated With Differences in Cortisol Excretion in Patients With Secondary Adrenal Insufficiency.
Frontiers in endocrinology.
2022; 13(?):849188. doi:
10.3389/fendo.2022.849188. [PMID: 35518935] - G Mayne, E De Bloois, D Dabelea, U Christians. Development and validation of an LC-MS/MS assay for the quantification of allopregnanolone and its progesterone-derived isomers, precursors, and cortisol/cortisone in pregnancy.
Analytical and bioanalytical chemistry.
2021 Sep; 413(21):5427-5438. doi:
10.1007/s00216-021-03523-0. [PMID: 34279681] - Alejandra Tapia-Castillo, Cristian A Carvajal, Xaviera López-Cortés, Andrea Vecchiola, Carlos E Fardella. Novel metabolomic profile of subjects with non-classic apparent mineralocorticoid excess.
Scientific reports.
2021 08; 11(1):17156. doi:
10.1038/s41598-021-96628-6. [PMID: 34433879] - Pinar Gumus Balikcioglu, Metin Balikcioglu, Arlette Soros, Stuart Chalew. The 24-hour average concentration of cortisol is elevated in obese African-American youth with type 2 diabetes.
Journal of diabetes and its complications.
2021 07; 35(7):107933. doi:
10.1016/j.jdiacomp.2021.107933. [PMID: 33902997] - Tania Pilli, Sandro Cardinale, Silvia Cantara, Gilda Dalmazio, Raffaella Forleo, Marco Capezzone, Cristian Bassi, Massimo Negrini, Manuela Ferracin, Maria Grazia Castagna. Preliminary results from whole-genome expression analysis in patients with secondary adrenal insufficiency treated with modified-release hydrocortisone.
Endocrine.
2021 07; 73(1):177-185. doi:
10.1007/s12020-020-02578-w. [PMID: 33417142] - Dandan Wei, Shanshan Li, Li Zhang, Pengling Liu, Keliang Fan, Luting Nie, Lulu Wang, Xiaotian Liu, Jian Hou, Songcheng Yu, Linlin Li, Tao Jing, Xing Li, Wenjie Li, Yuming Guo, Chongjian Wang, Wenqian Huo, Zhenxing Mao. Long-term exposure to PM1 and PM2.5 is associated with serum cortisone level and meat intake plays a moderation role.
Ecotoxicology and environmental safety.
2021 Jun; 215(?):112133. doi:
10.1016/j.ecoenv.2021.112133. [PMID: 33740488] - Janina Tokarz, Stefan M Schmitt, Gabriele Möller, André W Brändli, Jerzy Adamski. Functional characterization of two 20β-hydroxysteroid dehydrogenase type 2 homeologs from Xenopus laevis reveals multispecificity.
The Journal of steroid biochemistry and molecular biology.
2021 06; 210(?):105874. doi:
10.1016/j.jsbmb.2021.105874. [PMID: 33722706] - Yepu He, Liyu Xu, Yanbing Li, Yinying Tang, Shuwen Rao, Rongtian Lin, Zhijun Liu, Heru Chen. Synergistic integration of dihydro-artemisinin with γ-aminobutyric acid results in a more potential anti-depressant.
Bioorganic chemistry.
2021 05; 110(?):104769. doi:
10.1016/j.bioorg.2021.104769. [PMID: 33677247] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Giulia Carosi, Valentina Morelli, Giulia Del Sindaco, Andreea Liliana Serban, Arianna Cremaschi, Sofia Frigerio, Giulia Rodari, Eriselda Profka, Rita Indirli, Roberta Mungari, Veronica Resi, Emanuela Orsi, Emanuele Ferrante, Alessia Dolci, Claudia Giavoli, Maura Arosio, Giovanna Mantovani. Adrenal Insufficiency at the Time of COVID-19: A Retrospective Study in Patients Referring to a Tertiary Center.
The Journal of clinical endocrinology and metabolism.
2021 03; 106(3):e1354-e1361. doi:
10.1210/clinem/dgaa793. [PMID: 34932807] - Stéphanie Espiard, Johanna McQueen, Mark Sherlock, Oskar Ragnarsson, Ragnhildur Bergthorsdottir, Pia Burman, Per Dahlqvist, Bertil Ekman, Britt Edén Engström, Stanko Skrtic, Jeanette Wahlberg, Paul M Stewart, Gudmundur Johannsson. Improved Urinary Cortisol Metabolome in Addison Disease: A Prospective Trial of Dual-Release Hydrocortisone.
The Journal of clinical endocrinology and metabolism.
2021 03; 106(3):814-825. doi:
10.1210/clinem/dgaa862. [PMID: 33236103] - Chisato Shimanoe, Akiko Matsumoto, Megumi Hara, Chiho Akao, Yuichiro Nishida, Mikako Horita, Hinako Nanri, Yasuki Higaki, Keitaro Tanaka. Perceived stress, depressive symptoms, and cortisol-to-cortisone ratio in spot urine in 6878 older adults.
Psychoneuroendocrinology.
2021 03; 125(?):105125. doi:
10.1016/j.psyneuen.2020.105125. [PMID: 33429220] - Julie Brossaud, Léa Charret, Delia De Angeli, Magalie Haissaguerre, Amandine Ferriere, Marie Puerto, Blandine Gatta-Cherifi, Jean-Benoît Corcuff, Antoine Tabarin. Hair cortisol and cortisone measurements for the diagnosis of overt and mild Cushing's syndrome.
European journal of endocrinology.
2021 Mar; 184(3):445-454. doi:
10.1530/eje-20-1127. [PMID: 33449913] - Lahari Vuppaladhadiam, Jeannette Lager, Oliver Fiehn, Sandra Weiss, Margaret Chesney, Burcu Hasdemir, Aditi Bhargava. Human Placenta Buffers the Fetus from Adverse Effects of Perceived Maternal Stress.
Cells.
2021 02; 10(2):. doi:
10.3390/cells10020379. [PMID: 33673157] - Joëlle C Schutten, Peter J Joris, Isidor Minović, Adrian Post, André P van Beek, Martin H de Borst, Ronald P Mensink, Stephan J L Bakker. Long-term magnesium supplementation improves glucocorticoid metabolism: A post-hoc analysis of an intervention trial.
Clinical endocrinology.
2021 02; 94(2):150-157. doi:
10.1111/cen.14350. [PMID: 33030273] - S J Weaver, P I Hynd, C R Ralph, J E Hocking Edwards, C L Burnard, E Narayan, A J Tilbrook. Chronic elevation of plasma cortisol causes differential expression of predominating glucocorticoid in plasma, saliva, fecal, and wool matrices in sheep.
Domestic animal endocrinology.
2021 01; 74(?):106503. doi:
10.1016/j.domaniend.2020.106503. [PMID: 32846373] - Julie Brossaud, Jean-Benoît Corcuff, Vanessa Vautier, Aude Bergeron, Aurelie Valade, Anne Lienhardt, Marie-Pierre Moisan, Pascal Barat. Altered Cortisol Metabolism Increases Nocturnal Cortisol Bioavailability in Prepubertal Children With Type 1 Diabetes Mellitus.
Frontiers in endocrinology.
2021; 12(?):742669. doi:
10.3389/fendo.2021.742669. [PMID: 34970219] - L A Vaira, C Hopkins, A Sandison, A Manca, N Machouchas, D Turilli, J R Lechien, M R Barillari, G Salzano, A Cossu, S Saussez, G De Riu. Olfactory epithelium histopathological findings in long-term coronavirus disease 2019 related anosmia.
The Journal of laryngology and otology.
2020 Dec; 134(12):1123-1127. doi:
10.1017/s0022215120002455. [PMID: 33190655] - Gianmarco Stati, Silvia Sancilio, Mariangela Basile, Antonio Angelini, Roberta Di Pietro. Curcuma longa aqueous extract: A potential solution for the prevention of corneal scarring as a result of pterygium surgical excision (Review).
International journal of molecular medicine.
2020 Dec; 46(6):1951-1957. doi:
10.3892/ijmm.2020.4738. [PMID: 33125502] - Carina Ankarberg-Lindgren, Mats X Andersson, Jovanna Dahlgren. Determination of estrone sulfate, testosterone, androstenedione, DHEAS, cortisol, cortisone, and 17α-hydroxyprogesterone by LC-MS/MS in children and adolescents.
Scandinavian journal of clinical and laboratory investigation.
2020 Dec; 80(8):672-680. doi:
10.1080/00365513.2020.1829699. [PMID: 33258387] - Magdalena Maciuszek, Katarzyna Klak, Leszek Rydz, B M Lidy Verburg-van Kemenade, Magdalena Chadzinska. Cortisol Metabolism in Carp Macrophages: A Role for Macrophage-Derived Cortisol in M1/M2 Polarization.
International journal of molecular sciences.
2020 Nov; 21(23):. doi:
10.3390/ijms21238954. [PMID: 33255713] - Andrew Titman, Victoria Price, Daniel Hawcutt, Chris Chesters, Murtaza Ali, Gianluca Cacace, Gill A Lancaster, Matthew Peak, Joanne C Blair. Salivary cortisol, cortisone and serum cortisol concentrations are related to age and body mass index in healthy children and young people.
Clinical endocrinology.
2020 11; 93(5):572-578. doi:
10.1111/cen.14294. [PMID: 32688436] - Joanne E Adaway, James M Hawley, Stephen J Lockhart, Brian G Keevil. Heat Inactivation of Saliva Samples for the Analysis of Cortisol and Cortisone during the COVID-19 Pandemic.
The journal of applied laboratory medicine.
2020 Nov; 5(6):1413-1416. doi:
10.1093/jalm/jfaa158. [PMID: 32853331] - Tejas Kalaria, Mayuri Agarwal, Sukhbir Kaur, Lauren Hughes, Hayley Sharrod-Cole, Rahul Chaudhari, Carolina Gherman-Ciolac, Roopa Chopra, Victor Okeke, Clare Ford, Harit Buch, Rousseau Gama. Hypothalamic-pituitary-adrenal axis suppression - The value of salivary cortisol and cortisone in assessing hypothalamic-pituitary-adrenal recovery.
Annals of clinical biochemistry.
2020 11; 57(6):456-460. doi:
10.1177/0004563220961745. [PMID: 32961064] - Vânia Brazão, Fabricia Helena Santello, Rafaela Pravato Colato, Andressa Duarte, Amanda Goulart, Pedro Alexandre Sampaio, Viviani Nardini, Carlos Arterio Sorgi, Lúcia Helena Faccioli, José Clóvis do Prado. Melatonin down-regulates steroidal hormones, thymocyte apoptosis and inflammatory cytokines in middle-aged T. cruzi infected rats.
Biochimica et biophysica acta. Molecular basis of disease.
2020 11; 1866(11):165914. doi:
10.1016/j.bbadis.2020.165914. [PMID: 32768678] - Rosemary Dineen, Lucy-Ann Behan, Grainne Kelleher, Mark J Hannon, Jennifer J Brady, Bairbre Rogers, Brian G Keevil, William Tormey, Diarmuid Smith, Christopher J Thompson, Malachi J McKenna, Wiebke Arlt, Paul M Stewart, Amar Agha, Mark Sherlock. The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy.
BMC endocrine disorders.
2020 Oct; 20(1):154. doi:
10.1186/s12902-020-00633-1. [PMID: 33036588] - Dandan Wei, Xue Liu, Wenqian Huo, Songcheng Yu, Linlin Li, Chongjian Wang, Zhenxing Mao. Serum cortisone and glucocorticoid receptor gene (NR3C1) polymorphism in human dysglycemia.
Hormones (Athens, Greece).
2020 Sep; 19(3):385-393. doi:
10.1007/s42000-020-00196-9. [PMID: 32304041] - La-Or Chailurkit, Wichai Aekplakorn, Nitchawat Paiyabhroma, Boonsong Ongphiphadhanakul. Global 11 Beta-Hydroxysteroid Dehydrogenase Activity Assessed by the Circulating Cortisol to Cortisone Ratio is Associated with Features of Metabolic Syndrome.
Metabolic syndrome and related disorders.
2020 08; 18(6):291-295. doi:
10.1089/met.2020.0013. [PMID: 32357081] - Anja Fenger Dreyer, Richard Christian Jensen, Dorte Glintborg, Anne Vibeke Schmedes, Ivan Brandslund, Flemming Nielsen, Henriette Boye Kyhl, Tina Kold Jensen, Marianne Skovsager Andersen. Perfluoroalkyl Substance Exposure Early In Pregnancy Was Negatively Associated With Late Pregnancy Cortisone Levels.
The Journal of clinical endocrinology and metabolism.
2020 08; 105(8):. doi:
10.1210/clinem/dgaa292. [PMID: 32436946] - Alessandro Prete, Angela E Taylor, Irina Bancos, David J Smith, Mark A Foster, Sibylle Kohler, Violet Fazal-Sanderson, John Komninos, Donna M O'Neil, Dimitra A Vassiliadi, Christopher J Mowatt, Radu Mihai, Joanne L Fallowfield, Djillali Annane, Janet M Lord, Brian G Keevil, John A H Wass, Niki Karavitaki, Wiebke Arlt. Prevention of Adrenal Crisis: Cortisol Responses to Major Stress Compared to Stress Dose Hydrocortisone Delivery.
The Journal of clinical endocrinology and metabolism.
2020 07; 105(7):. doi:
10.1210/clinem/dgaa133. [PMID: 32170323] - Nurcan Boyacioglu, Sultan Ozkan. The Effect of Noise in the Intensive Care Unit on the Oxidative Stress Response in Rats.
Biological research for nursing.
2020 07; 22(3):397-402. doi:
10.1177/1099800420923397. [PMID: 32390468] - Z R Shafigullina, L I Velikanova, N V Vorokhobina, E V Malevanaya, E G Strelnikova, Z V Pal'cman. [The combination of classical tests and methods of chromatography for laboratory diagnostics of cushing's syndrome of different genesis.].
Klinicheskaia laboratornaia diagnostika.
2020 Jun; 65(7):418-423. doi:
10.18821/0869-2084-2020-65-7-418-423. [PMID: 32762179] - Daniel Paul Fudulu, Gianni Davide Angelini, Fani Fanoula Papadopoulou, Jonathan Evans, Terrie Walker-Smith, Ido Kema, Martijn van Faassen, Serban Stoica, Massimo Caputo, Stafford Lightman, Benjamin Gibbison. The Peacock study: feasibility of the dynamic characterisation of the paediatric hypothalamic-pituitary-adrenal function during and after cardiac surgery.
BMC cardiovascular disorders.
2020 05; 20(1):245. doi:
10.1186/s12872-020-01516-y. [PMID: 32450805] - Cristian A Carvajal, Alejandra Tapia-Castillo, Andrea Vecchiola, Rene Baudrand, Carlos E Fardella. Classic and Nonclassic Apparent Mineralocorticoid Excess Syndrome.
The Journal of clinical endocrinology and metabolism.
2020 04; 105(4):. doi:
10.1210/clinem/dgz315. [PMID: 31909799] - E F Bode, G R Markby, A M Boag, Y Martinez-Pereira, B M Corcoran, C Farquharson, K Sooy, N Z M Homer, P M Jamieson, G J Culshaw. Glucocorticoid metabolism and the action of 11 beta-hydroxysteroid dehydrogenase 2 in canine congestive heart failure.
Veterinary journal (London, England : 1997).
2020 Apr; 258(?):105456. doi:
10.1016/j.tvjl.2020.105456. [PMID: 32564866] - Annet Vulto, Isidor Minović, Laura V de Vries, Arwin C Timmermans, Martijn van Faassen, Antonio W Gomes Neto, Daan J Touw, Margriet F C de Jong, André P van Beek, Robin P F Dullaart, Gerjan Navis, Ido P Kema, Stephan J L Bakker. Endogenous urinary glucocorticoid metabolites and mortality in prednisolone-treated renal transplant recipients.
Clinical transplantation.
2020 04; 34(4):e13824. doi:
10.1111/ctr.13824. [PMID: 32052523] - Sunil K Panigrahi, Cristina D Toedesbusch, Jennifer S McLeland, Brendan P Lucey, Sharon L Wardlaw. Diurnal Patterns for Cortisol, Cortisone and Agouti-Related Protein in Human Cerebrospinal Fluid and Blood.
The Journal of clinical endocrinology and metabolism.
2020 04; 105(4):. doi:
10.1210/clinem/dgz274. [PMID: 31838496] - Chongpeng Bi, Jiajia Yin, Wei Yang, Baoming Shi, Anshan Shan. Effects of dietary γ-aminobutyric acid supplementation on antioxidant status, blood hormones and meat quality in growing-finishing pigs undergoing transport stress.
Journal of animal physiology and animal nutrition.
2020 Mar; 104(2):590-596. doi:
10.1111/jpn.13280. [PMID: 31867827] - Britt J van Keulen, Conor V Dolan, Ruth Andrew, Brian R Walker, Hilleke E Hulshoff Pol, Dorret I Boomsma, Joost Rotteveel, Martijn J J Finken. Long-Term Stability of Cortisol Production and Metabolism Throughout Adolescence: Longitudinal Twin Study.
Twin research and human genetics : the official journal of the International Society for Twin Studies.
2020 02; 23(1):33-38. doi:
10.1017/thg.2020.6. [PMID: 32209144] - Yifan Hua, Jonas Esche, Michaela F Hartmann, Christiane Maser-Gluth, Stefan A Wudy, Thomas Remer. Cortisol and 11 beta-hydroxysteroid dehydrogenase type 2 as potential determinants of renal citrate excretion in healthy children.
Endocrine.
2020 02; 67(2):442-448. doi:
10.1007/s12020-019-02151-0. [PMID: 31813102] - Beate Wild, Judith Brenner, Stefanie Joos, Yvonne Samstag, Magdalena Buckert, Jan Valentini. Acupuncture in persons with an increased stress level-Results from a randomized-controlled pilot trial.
PloS one.
2020; 15(7):e0236004. doi:
10.1371/journal.pone.0236004. [PMID: 32701984] - Nuran Kucuk, Zehra Yavas Abalı, Saygın Abalı, Nur Canpolat, Gozde Yesil, Serap Turan, Abdullah Bereket, Tulay Guran. A rare cause of hypertension in childhood: Answers.
Pediatric nephrology (Berlin, Germany).
2020 01; 35(1):79-82. doi:
10.1007/s00467-019-04329-0. [PMID: 31541304] - Judith E Heida, Isidor Minović, Martijn van Faassen, Ido P Kema, Wendy E Boertien, Stephan J L Bakker, André P van Beek, Ron T Gansevoort. Effect of Vasopressin on the Hypothalamic-Pituitary-Adrenal Axis in ADPKD Patients during V2 Receptor Antagonism.
American journal of nephrology.
2020; 51(11):861-870. doi:
10.1159/000511000. [PMID: 33147589] - Eetmad A Arafat, Dalia A Shabaan. Fluoxetine ameliorates adult hippocampal injury in rats after early maternal separation. A biochemical, histological and immunohistochemical study.
Biotechnic & histochemistry : official publication of the Biological Stain Commission.
2020 Jan; 95(1):55-68. doi:
10.1080/10520295.2019.1637021. [PMID: 31570007] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Pierluigi Capra, Marta Leporati, Carlo Nebbia, Stefano Gatto, Alberto Attucci, Gandolfo Barbarino, Marco Vincenti. Effects of truck transportation and slaughtering on the occurrence of prednisolone and its metabolites in cow urine, liver, and adrenal glands.
BMC veterinary research.
2019 Sep; 15(1):336. doi:
10.1186/s12917-019-2069-4. [PMID: 31533706] - Julia Breedh, Erika Comasco, Charlotte Hellgren, Fotios C Papadopoulos, Alkistis Skalkidou, Inger Sundström Poromaa. Hypothalamic-pituitary-adrenal axis responsiveness, startle response, and sensorimotor gating in late pregnancy.
Psychoneuroendocrinology.
2019 08; 106(?):1-8. doi:
10.1016/j.psyneuen.2019.03.008. [PMID: 30927623] - L Yan, J Yu, Z Chen, R Chen, H Zhu, J Yan, Z Shi. Glucocorticoid receptor involvement in goose (Anas cygnoides) pituitary somatotroph differentiation induced by glucocorticoids during embryonic development.
British poultry science.
2019 Aug; 60(4):395-403. doi:
10.1080/00071668.2019.1621988. [PMID: 31132872] - Adree Khondker, Jochen S Hub, Maikel C Rheinstädter. Steroid-steroid interactions in biological membranes: Cholesterol and cortisone.
Chemistry and physics of lipids.
2019 07; 221(?):193-197. doi:
10.1016/j.chemphyslip.2019.04.003. [PMID: 30951711] - Nimesh A Jayasuriya, Alice E Hughes, Ulla Sovio, Emma Cook, D Stephen Charnock-Jones, Gordon C S Smith. A Lower Maternal Cortisol-to-Cortisone Ratio Precedes Clinical Diagnosis of Preterm and Term Preeclampsia by Many Weeks.
The Journal of clinical endocrinology and metabolism.
2019 06; 104(6):2355-2366. doi:
10.1210/jc.2018-02312. [PMID: 30768664] - Andrea Oßwald, Rong Wang, Felix Beuschlein, Michaela F Hartmann, Stefan A Wudy, Martin Bidlingmaier, Stephanie Zopp, Martin Reincke, Katrin Ritzel. Performance of LC-MS/MS and immunoassay based 24-h urine free cortisol in the diagnosis of Cushing's syndrome.
The Journal of steroid biochemistry and molecular biology.
2019 06; 190(?):193-197. doi:
10.1016/j.jsbmb.2019.04.004. [PMID: 30959155] - Francesca Bonelli, Alessandra Rota, Christine Aurich, Natascha Ille, Francesco Camillo, Duccio Panzani, Micaela Sgorbini. Determination of Salivary Cortisol in Donkey Stallions.
Journal of equine veterinary science.
2019 06; 77(?):68-71. doi:
10.1016/j.jevs.2019.02.027. [PMID: 31133319] - T S Send, S Bardtke, M Gilles, I A C Wolf, M W Sütterlin, S A Wudy, R Wang, M Laucht, S H Witt, M Rietschel, F Streit, M Deuschle. Prenatal maternal stress is associated with lower cortisol and cortisone levels in the first morning urine of 45-month-old children.
Psychoneuroendocrinology.
2019 05; 103(?):219-224. doi:
10.1016/j.psyneuen.2019.01.017. [PMID: 30711899] - Tobias Nicolas Rojas, David Lautaro Vergara-Tabares, Diego Javier Valdez, Marina Flavia Ponzio, Susana Inés Peluc. Food supplementation by an invasive fleshy-fruited shrub sustains body condition of a native frugivorous bird during winter.
Integrative zoology.
2019 May; 14(3):259-269. doi:
10.1111/1749-4877.12353. [PMID: 30019849] - Hyun-Sun Park, Hye-Youn Son, Min-Ha Choi, Youngsook Son, Sundong Kim, Hyun-Sook Hong, Ji-Ung Park. Adipose-derived stem cells attenuate atopic dermatitis-like skin lesions in NC/Nga mice.
Experimental dermatology.
2019 03; 28(3):300-307. doi:
10.1111/exd.13895. [PMID: 30688372] - Robert F Harrison, Miguel Debono, Martin J Whitaker, Brian G Keevil, John Newell-Price, Richard J Ross. Salivary Cortisone to Estimate Cortisol Exposure and Sampling Frequency Required Based on Serum Cortisol Measurements.
The Journal of clinical endocrinology and metabolism.
2019 03; 104(3):765-772. doi:
10.1210/jc.2018-01172. [PMID: 30285244] - Alejandra Tapia-Castillo, Rene Baudrand, Anand Vaidya, Carmen Campino, Fidel Allende, Carolina Valdivia, Andrea Vecchiola, Carlos F Lagos, Cristóbal A Fuentes, Sandra Solari, Alejandro Martínez-Aguayo, Hernán García, Cristian A Carvajal, Carlos E Fardella. Clinical, Biochemical, and Genetic Characteristics of "Nonclassic" Apparent Mineralocorticoid Excess Syndrome.
The Journal of clinical endocrinology and metabolism.
2019 02; 104(2):595-603. doi:
10.1210/jc.2018-01197. [PMID: 30239803] - Xue Liu, Jingjing Jiang, Xiaotian Liu, Zhicheng Luo, Yan Wang, Xiaokang Dong, Dandan Wei, Wenqian Huo, Songcheng Yu, Linlin Li, Shuna Jin, Chongjian Wang, Zhenxing Mao. Gender-Specific Independent and Combined Effects of the Cortisol-to-Cortisone Ratio and 11-Deoxycortisol on Prediabetes and Type 2 Diabetes Mellitus: From the Henan Rural Cohort Study.
Journal of diabetes research.
2019; 2019(?):4693817. doi:
10.1155/2019/4693817. [PMID: 31281850] - Katarzyna Kosicka, Anna Siemiątkowska, Agata Szpera-Goździewicz, Mariola Krzyścin, Grzegorz Bręborowicz, Franciszek Główka. High-performance liquid chromatography methods for the analysis of endogenous cortisol and cortisone in human urine: comparison of mass spectrometry and fluorescence detection.
Annals of clinical biochemistry.
2019 01; 56(1):82-89. doi:
10.1177/0004563218783789. [PMID: 29848040] - Andrew HyoungJin Kim, Sumin Yoon, Yujin Lee, Jieon Lee, Eunjin Bae, Hajeong Lee, Dong Ki Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Joo-Youn Cho. Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment.
Journal of Korean medical science.
2018 Dec; 33(53):e298. doi:
10.3346/jkms.2018.33.e298. [PMID: 30595680] - Amar Agha, Lucy Ann Behan, Hannah Forde, Norman F Taylor, Diarmuid Smith, Christopher J Thompson, William M Drake, John P Monson. DIFFERENTIAL REGULATION OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ACTIVITY IN PATIENTS WITH DIFFERING ETIOLOGIES OF HYPOPITUITARISM.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.
2018 Oct; 24(10):875-881. doi:
10.4158/ep-2018-0154. [PMID: 29975580] - Chengcheng Xiang, Shidai Jin, Juan Zhang, Minjian Chen, Yankai Xia, Yongqian Shu, Renhua Guo. Cortisol, cortisone, and 4-methoxyphenylacetic acid as potential plasma biomarkers for early detection of non-small cell lung cancer.
The International journal of biological markers.
2018 Aug; 33(3):314-320. doi:
10.1177/1724600818778754. [PMID: 29896992] - Kathleen M Gavin, Karen L Shea, Ellie Gibbons, Pamela Wolfe, Robert S Schwartz, Margaret E Wierman, Wendy M Kohrt. Gonadotropin-releasing hormone agonist in premenopausal women does not alter hypothalamic-pituitary-adrenal axis response to corticotropin-releasing hormone.
American journal of physiology. Endocrinology and metabolism.
2018 08; 315(2):E316-E325. doi:
10.1152/ajpendo.00221.2017. [PMID: 29631362] - Cristian A Carvajal, Alejandra Tapia-Castillo, Carolina P Valdivia, Fidel Allende, Sandra Solari, Carlos F Lagos, Carmen Campino, Alejandro Martínez-Aguayo, Andrea Vecchiola, Constanza Pinochet, Claudia Godoy, Virginia Iturrieta, Rene Baudrand, Carlos E Fardella. Serum Cortisol and Cortisone as Potential Biomarkers of Partial 11β-Hydroxysteroid Dehydrogenase Type 2 Deficiency.
American journal of hypertension.
2018 07; 31(8):910-918. doi:
10.1093/ajh/hpy051. [PMID: 29617893] - Katarzyna Kosicka, Anna Siemiątkowska, Agata Szpera-Goździewicz, Mariola Krzyścin, Grzegorz H Bręborowicz, Franciszek K Główka. Increased cortisol metabolism in women with pregnancy-related hypertension.
Endocrine.
2018 07; 61(1):125-133. doi:
10.1007/s12020-018-1586-4. [PMID: 29611097] - Michael Conall Dennedy. Salivary cortisone and cortisol following synacthen, a future replacement for serum cortisol? Commentary to: Use of Salivary Cortisol and cortisone in the high and low dose synacthen test.
Clinical endocrinology.
2018 06; 88(6):770-771. doi:
10.1111/cen.13585. [PMID: 29485708] - Charlotte J Elder, Robert F Harrison, Alexandra S Cross, Ruben Vilela, Brian G Keevil, Neil P Wright, Richard J Ross. Use of salivary cortisol and cortisone in the high- and low-dose synacthen test.
Clinical endocrinology.
2018 06; 88(6):772-778. doi:
10.1111/cen.13509. [PMID: 29106701] - Aniko Krumbholz, Martin Schönfelder, Hande Hofmann, Detlef Thieme. The plasma protein binding of the endogenous glucocorticosteroids is of vital importance for the concentrations in hair and saliva.
Forensic science international.
2018 May; 286(?):23-30. doi:
10.1016/j.forsciint.2018.01.030. [PMID: 29547783] - Marlen Israelsson, Ralph Brattsand, Göran Brattsand. 20α- and 20β-dihydrocortisone may interfere in LC-MS/MS determination of cortisol in saliva and urine.
Annals of clinical biochemistry.
2018 May; 55(3):341-347. doi:
10.1177/0004563217724178. [PMID: 28726485] - Laura I Stirrat, Jamie J Walker, Ksenia Stryjakowska, Natalie Jones, Natalie Z M Homer, Ruth Andrew, Jane E Norman, Stafford L Lightman, Rebecca M Reynolds. Pulsatility of glucocorticoid hormones in pregnancy: Changes with gestation and obesity.
Clinical endocrinology.
2018 04; 88(4):592-600. doi:
10.1111/cen.13548. [PMID: 29314170] - Johanna M Lindner, Anna Catharina Suhr, Stefanie H Grimm, Patrick Möhnle, Michael Vogeser, Josef Briegel. The dynamics of a serum steroid profile after stimulation with intravenous ACTH.
Journal of pharmaceutical and biomedical analysis.
2018 Mar; 151(?):159-163. doi:
10.1016/j.jpba.2017.12.045. [PMID: 29346086] - Yuki Kageyama, Takaoki Kasahara, Takemichi Nakamura, Kotaro Hattori, Yasuhiko Deguchi, Munehide Tani, Kenji Kuroda, Sumiko Yoshida, Yu-Ichi Goto, Koki Inoue, Tadafumi Kato. Plasma Nervonic Acid Is a Potential Biomarker for Major Depressive Disorder: A Pilot Study.
The international journal of neuropsychopharmacology.
2018 03; 21(3):207-215. doi:
10.1093/ijnp/pyx089. [PMID: 29040586] - D F Cobice, D E W Livingstone, A McBride, C L MacKay, B R Walker, S P Webster, R Andrew. Quantification of 11β-hydroxysteroid dehydrogenase 1 kinetics and pharmacodynamic effects of inhibitors in brain using mass spectrometry imaging and stable-isotope tracers in mice.
Biochemical pharmacology.
2018 02; 148(?):88-99. doi:
10.1016/j.bcp.2017.12.013. [PMID: 29248595] - Kate C Verbeeten, Alexandra H Ahmet. The role of corticosteroid-binding globulin in the evaluation of adrenal insufficiency.
Journal of pediatric endocrinology & metabolism : JPEM.
2018 Jan; 31(2):107-115. doi:
10.1515/jpem-2017-0270. [PMID: 29194043] - M Vasku, N Kleine-Eggebrecht, W Rath, M G Mohaupt, G Escher, U Pecks. Apparent systemic 11ß-dehydroxysteroid dehydrogenase 2 activity is increased in preeclampsia but not in intrauterine growth restriction.
Pregnancy hypertension.
2018 Jan; 11(?):7-11. doi:
10.1016/j.preghy.2017.11.012. [PMID: 29523277] - Birthe R Dahlerup, Emilie L Egsmose, Volkert Siersma, Erik L Mortensen, Morten Hedegaard, Lisbeth E Knudsen, Line Mathiesen. Maternal stress and placental function, a study using questionnaires and biomarkers at birth.
PloS one.
2018; 13(11):e0207184. doi:
10.1371/journal.pone.0207184. [PMID: 30439989] - Aleid Jg Wirix, Martijn Jj Finken, Ines A von Rosenstiel-Jadoul, Annemieke C Heijboer, Jeroen Nauta, Jaap W Groothoff, Mai Jm Chinapaw, Joana E Kist-van Holthe. Is There an Association Between Cortisol and Hypertension in Overweight or Obese Children?.
Journal of clinical research in pediatric endocrinology.
2017 12; 9(4):344-349. doi:
10.4274/jcrpe.4802. [PMID: 28720554] - C M Ng, T K Lam, Y C Au Yeung, C H Choi, Y P Iu, C C Shek, S C Tiu. Clinical utility of late-night and post-overnight dexamethasone suppression salivary cortisone for the investigation of Cushing's syndrome.
Hong Kong medical journal = Xianggang yi xue za zhi.
2017 Dec; 23(6):570-8. doi:
10.12809/hkmj176240. [PMID: 29026058] - Filippo Ceccato, Laura Trementino, Mattia Barbot, Giorgia Antonelli, Mario Plebani, Luca Denaro, Daniela Regazzo, Federico Rea, Anna Chiara Frigo, Carolina Concettoni, Marco Boscaro, Giorgio Arnaldi, Carla Scaroni. Diagnostic accuracy of increased urinary cortisol/cortisone ratio to differentiate ACTH-dependent Cushing's syndrome.
Clinical endocrinology.
2017 Nov; 87(5):500-507. doi:
10.1111/cen.13391. [PMID: 28590513] - L Chiesa, S Pavone, E Pasquale, R Pavlovic, S Panseri, A Valiani, F Arioli, E Manuali. Study on cortisol, cortisone and prednisolone presence in urine of Chianina cattle breed.
Journal of animal physiology and animal nutrition.
2017 Oct; 101(5):893-903. doi:
10.1111/jpn.12509. [PMID: 27080058] - Marta Leporati, Maria Nobile, Pierluigi Capra, Eugenio Alladio, Marco Vincenti. Determination of endogenous and exogenous corticosteroids in bovine urine and effect of fighting stress during the 'Batailles des Reines' on their biosynthesis.
Research in veterinary science.
2017 Oct; 114(?):423-429. doi:
10.1016/j.rvsc.2017.06.014. [PMID: 28755555] - Chen Li, Zhao Zhang, Xiongwei Liu, Kangwei Shen, Pan Gu, Xuejun Kang. Simultaneous quantification of cortisol and cortisone in urines from infants with packed-fiber solid-phase extraction coupled to HPLC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Sep; 1061-1062(?):163-168. doi:
10.1016/j.jchromb.2017.07.012. [PMID: 28735224] - Miguel Debono, Robert F Harrison, Rita Chadarevian, Carole Gueroult, Jean-Louis Abitbol, John Newell-Price. Resetting the Abnormal Circadian Cortisol Rhythm in Adrenal Incidentaloma Patients With Mild Autonomous Cortisol Secretion.
The Journal of clinical endocrinology and metabolism.
2017 09; 102(9):3461-3469. doi:
10.1210/jc.2017-00823. [PMID: 28911138] - Huichu Li, Jing Cai, Renjie Chen, Zhuohui Zhao, Zhekang Ying, Lin Wang, Jianmin Chen, Ke Hao, Patrick L Kinney, Honglei Chen, Haidong Kan. Particulate Matter Exposure and Stress Hormone Levels: A Randomized, Double-Blind, Crossover Trial of Air Purification.
Circulation.
2017 Aug; 136(7):618-627. doi:
10.1161/circulationaha.116.026796. [PMID: 28808144] - Akiko Matsumoto, Chisato Shimanoe, Keitaro Tanaka, Masayoshi Ichiba, Megumi Hara. Development of suitable method for large-scale urinary glucocorticoid analysis by liquid chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Jul; 1057(?):62-69. doi:
10.1016/j.jchromb.2017.04.031. [PMID: 28505491]
