C26:0 (BioDeep_00000628677)

Main id: BioDeep_00000014275

 


代谢物信息卡片


HEXACOSANOIC ACID

化学式: C26H52O2 (396.3967092)
中文名称: 蜡酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CCCCCCCCCCCCC(=O)O)CCCCCCCCCCCC
InChI: InChI=1S/C26H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26(27)28/h2-25H2,1H3,(H,27,28)

描述信息

同义名列表

8 个代谢物同义名

HEXACOSANOIC ACID; Ceratinic acid; Cerotic acid; Cerylic acid; Cerinic acid; Ceric acid; FA 26:0; C26:0



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

130 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xiao Wu, Yangyang Chen, Xinjie Shi, Kaijie Qi, Peng Cao, Xueying Liu, Hao Yin, Shaoling Zhang. Effects of palmitic acid (16:0), hexacosanoic acid (26:0), ethephon and methyl jasmonate on the cuticular wax composition, structure and expression of key gene in the fruits of three pear cultivars. Functional plant biology : FPB. 2020 02; 47(2):156-169. doi: 10.1071/fp19117. [PMID: 31930956]
  • Thomas Nury, Margaux Doria, Gérard Lizard, Anne Vejux. Docosahexaenoic Acid Attenuates Mitochondrial Alterations and Oxidative Stress Leading to Cell Death Induced by Very Long-Chain Fatty Acids in a Mouse Oligodendrocyte Model. International journal of molecular sciences. 2020 Jan; 21(2):. doi: 10.3390/ijms21020641. [PMID: 31963714]
  • Desirèe Padilha Marchetti, Luiza Steffens, Carlos E Jacques, Gilian B Guerreiro, Caroline P Mescka, Marion Deon, Daniella M de Coelho, Dinara J Moura, Alice G Viario, Fernanda Poletto, Adriana S Coitinho, Laura B Jardim, Carmen R Vargas. Oxidative Imbalance, Nitrative Stress, and Inflammation in C6 Glial Cells Exposed to Hexacosanoic Acid: Protective Effect of N-acetyl-L-cysteine, Trolox, and Rosuvastatin. Cellular and molecular neurobiology. 2018 Nov; 38(8):1505-1516. doi: 10.1007/s10571-018-0626-1. [PMID: 30302628]
  • Yan Song, Lan Pan, Wenjie Li, Yingying Si, Di Zhou, Chengjian Zheng, Xiaofang Hao, Xinyue Jia, Yuemei Jia, Minghui Shi, Xiaoguang Jia, Ning Li, Yue Hou. Natural neuro-inflammatory inhibitors from Caragana turfanensis. Bioorganic & medicinal chemistry letters. 2017 10; 27(20):4765-4769. doi: 10.1016/j.bmcl.2017.08.047. [PMID: 28911817]
  • Adriana Mika, Jaroslaw Kobiela, Aleksandra Czumaj, Michał Chmielewski, Piotr Stepnowski, Tomasz Sledzinski. Hyper-Elongation in Colorectal Cancer Tissue - Cerotic Acid is a Potential Novel Serum Metabolic Marker of Colorectal Malignancies. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2017; 41(2):722-730. doi: 10.1159/000458431. [PMID: 28214830]
  • Seshadri Shivashankar, Manoharan Sumathi. Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination?. Journal of biosciences. 2015 Jun; 40(2):375-87. doi: 10.1007/s12038-015-9515-7. [PMID: 25963264]
  • A Zarrouk, M Hammami, T Moreau, G Lizard. Accumulation of 24S-hydroxycholesterol in neuronal SK-N-BE cells treated with hexacosanoic acid (C26:0): argument in favor of 24S-hydroxycholesterol as a potential biomarker of neurolipotoxicity. Revue neurologique. 2015 Feb; 171(2):125-9. doi: 10.1016/j.neurol.2014.10.016. [PMID: 25577946]
  • Fahmi Nasrallah, Ichraf Kraoua, Wiem Zidi, Souheil Omar, Haifa Sanhaji, Moncef Feki, Ilhem Turki Ben Youssef, Naziha Kaabachi. X-linked Adrenoleukodystrophy, The Tunisian Experience. Clinical laboratory. 2015; 61(10):1531-6. doi: 10.7754/clin.lab.2015.150318. [PMID: 26642716]
  • Amira Zarrouk, Jean-Marc Riedinger, Samia Hadj Ahmed, Sonia Hammami, Wafa Chaabane, Meryam Debbabi, Sofiene Ben Ammou, Olivier Rouaud, Mahbouba Frih, Gérard Lizard, Mohamed Hammami. Fatty acid profiles in demented patients: identification of hexacosanoic acid (C26:0) as a blood lipid biomarker of dementia. Journal of Alzheimer's disease : JAD. 2015; 44(4):1349-59. doi: 10.3233/jad-142046. [PMID: 25428249]
  • Stefano Ginanni Corradini, Chiara Zerbinati, Federica Maldarelli, Giuseppina Palmaccio, Lucia Parlati, Anna Giulia Bottaccioli, Antonio Molinaro, Edoardo Poli, Mona Boaz, Gaetano Serviddio, Gianluca Mennini, Alessandro Corsi, Paolo Bianco, Massimo Rossi, Luigi Iuliano. Plasma fatty acid lipidome is associated with cirrhosis prognosis and graft damage in liver transplantation. The American journal of clinical nutrition. 2014 Aug; 100(2):600-8. doi: 10.3945/ajcn.113.074427. [PMID: 24965302]
  • Tetsuro Miyazaki, Kazunori Shimada, Makoto Hiki, Atsumi Kume, Yohei Kitamura, Kyoichi Oshida, Naotake Yanagisawa, Takashi Kiyanagi, Rie Matsumori, Hiroyuki Daida. High hexacosanoic acid levels are associated with coronary artery disease. Atherosclerosis. 2014 Apr; 233(2):429-433. doi: 10.1016/j.atherosclerosis.2014.01.031. [PMID: 24530774]
  • Ngoc A Dang, Hans-Gerd Janssen, Arend H J Kolk. Rapid diagnosis of TB using GC-MS and chemometrics. Bioanalysis. 2013 Dec; 5(24):3079-97. doi: 10.4155/bio.13.288. [PMID: 24320132]
  • Marc Engelen, Martin J A Schackmann, Rob Ofman, Robert-Jan Sanders, Inge M E Dijkstra, Sander M Houten, Stéphane Fourcade, Aurora Pujol, Bwee Tien Poll-The, Ronald J A Wanders, Stephan Kemp. Bezafibrate lowers very long-chain fatty acids in X-linked adrenoleukodystrophy fibroblasts by inhibiting fatty acid elongation. Journal of inherited metabolic disease. 2012 Nov; 35(6):1137-45. doi: 10.1007/s10545-012-9471-4. [PMID: 22447153]
  • Marco Cappa, Carla Bizzarri, Anna Petroni, Gianfranca Carta, Lina Cordeddu, Massimiliano Valeriani, Catello Vollono, Loredana De Pasquale, Milena Blasevich, Sebastiano Banni. A mixture of oleic, erucic and conjugated linoleic acids modulates cerebrospinal fluid inflammatory markers and improve somatosensorial evoked potential in X-linked adrenoleukodystrophy female carriers. Journal of inherited metabolic disease. 2012 Sep; 35(5):899-907. doi: 10.1007/s10545-011-9432-3. [PMID: 22189598]
  • Shiyou Lü, Huayan Zhao, David L Des Marais, Eugene P Parsons, Xiaoxue Wen, Xiaojing Xu, Dhinoth K Bangarusamy, Guangchao Wang, Owen Rowland, Thomas Juenger, Ray A Bressan, Matthew A Jenks. Arabidopsis ECERIFERUM9 involvement in cuticle formation and maintenance of plant water status. Plant physiology. 2012 Jul; 159(3):930-44. doi: 10.1104/pp.112.198697. [PMID: 22635115]
  • Francieli J Rockenbach, Marion Deon, Daiane P Marchese, Vanusa Manfredini, Caroline Mescka, Graziela S Ribas, Clarissa T Habekost, Claudio G Castro, Laura B Jardim, Carmen R Vargas. The effect of bone marrow transplantation on oxidative stress in X-linked adrenoleukodystrophy. Molecular genetics and metabolism. 2012 Jun; 106(2):231-6. doi: 10.1016/j.ymgme.2012.03.019. [PMID: 22525090]
  • Stefan Tresch, Monika Heilmann, Nicole Christiansen, Ralf Looser, Klaus Grossmann. Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases. Phytochemistry. 2012 Apr; 76(?):162-71. doi: 10.1016/j.phytochem.2011.12.023. [PMID: 22284369]
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  • Cheng Yuan, Junhan Liu, Yong Fan, Xiaohui Ren, Guangrong Hu, Fuli Li. Mychonastes afer HSO-3-1 as a potential new source of biodiesel. Biotechnology for biofuels. 2011 Nov; 4(1):47. doi: 10.1186/1754-6834-4-47. [PMID: 22040677]
  • M Cappa, C Bizzarri, G Giannone, C Aiello, A Di Biase. Is subclinical adrenal failure in adrenoleukodystrophy/adrenomyeloneuropathy reversible?. Journal of endocrinological investigation. 2011 Nov; 34(10):753-6. doi: 10.3275/7570. [PMID: 21399389]
  • Jie Feng, Xiuwei Yang. [Liposolubility constituents from leaves of Aquilaria sinensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Aug; 36(15):2092-5. doi: 10.4268/cjcmm20111517. [PMID: 22066446]
  • Yanjing Bai, Chihiro Tohda, Shu Zhu, Masao Hattori, Katsuko Komatsu. Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons. Journal of natural medicines. 2011 Jul; 65(3-4):417-23. doi: 10.1007/s11418-011-0509-y. [PMID: 21301979]
  • Wei-Yi Hsu, Wei-De Lin, Wuh-Liang Hwu, Chien-Chen Lai, Fuu-Jen Tsai. Screening assay of very long chain fatty acids in human plasma with multiwalled carbon nanotube-based surface-assisted laser desorption/ionization mass spectrometry. Analytical chemistry. 2010 Aug; 82(16):6814-20. doi: 10.1021/ac100772j. [PMID: 20704371]
  • Natalia Yu Ryabova, M A Kiselev, S Dante, T Hauss, A M Balagurov. Investigation of stratum corneum lipid model membranes with free fatty acid composition by neutron diffraction. European biophysics journal : EBJ. 2010 Jul; 39(8):1167-76. doi: 10.1007/s00249-009-0569-z. [PMID: 20012954]
  • Amanda K Broz, Corey D Broeckling, Clelia De-la-Peña, Matthew R Lewis, Erick Greene, Ragan M Callaway, Lloyd W Sumner, Jorge M Vivanco. Plant neighbor identity influences plant biochemistry and physiology related to defense. BMC plant biology. 2010 Jun; 10(?):115. doi: 10.1186/1471-2229-10-115. [PMID: 20565801]
  • M Aasim Khan, M Ali, Prawez Alam. Phytochemical investigation of the fruit peels of Citrus reticulata Blanco. Natural product research. 2010 Apr; 24(7):610-20. doi: 10.1080/14786410802425787. [PMID: 20401792]
  • Alastair Wilkins, Gillian Ingram, Anny Brown, Philip Jardine, Colin G Steward, Neil P Robertson, Neil J Scolding. Very long chain fatty acid levels in patients diagnosed with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2009 Dec; 15(12):1525-7. doi: 10.1177/1352458509351731. [PMID: 19965514]
  • Biju K Pillai, Ravi Jasuja, Jeffrey R Simard, James A Hamilton. Fast diffusion of very long chain saturated fatty acids across a bilayer membrane and their rapid extraction by cyclodextrins: implications for adrenoleukodystrophy. The Journal of biological chemistry. 2009 Nov; 284(48):33296-304. doi: 10.1074/jbc.m109.043737. [PMID: 19801636]
  • Niko Radulović, Polina Blagojević, Radosav Palić. Composition of diethyl ether flower extracts of Lonicera fragrantissima Lindl. & Paxton (caprifoliaceae). Natural product communications. 2009 Nov; 4(11):1581-4. doi: . [PMID: 19967996]
  • Tomás Rezanka, Karel Sigler. Odd-numbered very-long-chain fatty acids from the microbial, animal and plant kingdoms. Progress in lipid research. 2009 May; 48(3-4):206-38. doi: 10.1016/j.plipres.2009.03.003. [PMID: 19336244]
  • Alicia N Lorenzo Figueiras, Juan R Girotti, Sergio J Mijailovsky, M Patricia Juárez. Epicuticular lipids induce aggregation in Chagas disease vectors. Parasites & vectors. 2009 Jan; 2(1):8. doi: 10.1186/1756-3305-2-8. [PMID: 19173716]
  • Xiangmin Wang, Ke Liu, Hui Xu. [Studies on chemical constituents of aerial roots of Ficus microcarpa]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2009 Jan; 34(2):169-71. doi: ". [PMID: 19385177]
  • Naotake Yanagisawa, Kazunori Shimada, Tetsuro Miyazaki, Atsumi Kume, Yohei Kitamura, Katsuhiko Sumiyoshi, Takashi Kiyanagi, Takafumi Iesaki, Nao Inoue, Hiroyuki Daida. Enhanced production of nitric oxide, reactive oxygen species, and pro-inflammatory cytokines in very long chain saturated fatty acid-accumulated macrophages. Lipids in health and disease. 2008 Nov; 7(?):48. doi: 10.1186/1476-511x-7-48. [PMID: 19038055]
  • Atsumi Kume, Tetsuro Miyazaki, Yohei Kitamura, Kyoichi Oshida, Naotake Yanagisawab, Hirotaka Takizawa, Kiyotaka Fujii, Takashi Kiyanagi, Katsuhiko Sumiyoshi, Hirotoshi Ohmura, Hiroshi Mokuno, Kazunori Shimada, Hiroyuki Daida. High levels of saturated very long-chain fatty acid (hexacosanoic acid; C26:0) in whole blood are associated with metabolic syndrome in Japanese men. Diabetes research and clinical practice. 2008 May; 80(2):259-64. doi: 10.1016/j.diabres.2007.12.014. [PMID: 18242759]
  • Rita Di Benedetto, Michela Alessandra Denti, Serafina Salvati, Massimo Sanchez, Lucilla Attorri, Giulia David, Antonella Di Biase. RNAi-mediated silencing of ABCD3 gene expression in rat C6 glial cells: a model system to study PMP70 function. Neurochemistry international. 2008 May; 52(6):1106-13. doi: 10.1016/j.neuint.2007.11.007. [PMID: 18178290]
  • Tang-Chia Chung, Hwang-Shang Kou, Mei-Chyn Chao, Ying-Ju Ou, Hsin-Lung Wu. A simple and sensitive liquid chromatographic method for the analysis of free docosanoic, tetracosanoic and hexacosanoic acids in human plasma as fluorescent derivatives. Analytica chimica acta. 2008 Mar; 611(1):113-8. doi: 10.1016/j.aca.2008.01.062. [PMID: 18298975]
  • Marion Deon, Mariana Pires Garcia, Angela Sitta, Alethéa G Barschak, Daniella M Coelho, Graziela O Schimit, Maiara Pigatto, Laura B Jardim, Moacir Wajner, Roberto Giugliani, Carmen R Vargas. Hexacosanoic and docosanoic acids plasma levels in patients with cerebral childhood and asymptomatic X-linked adrenoleukodystrophy: Lorenzo's oil effect. Metabolic brain disease. 2008 Mar; 23(1):43-9. doi: 10.1007/s11011-007-9079-9. [PMID: 18026827]
  • Ana C Matias, Nuno Pedroso, Nuno Teodoro, H Susana Marinho, Fernando Antunes, José Manuel Nogueira, Enrique Herrero, Luísa Cyrne. Down-regulation of fatty acid synthase increases the resistance of Saccharomyces cerevisiae cells to H2O2. Free radical biology & medicine. 2007 Nov; 43(10):1458-65. doi: 10.1016/j.freeradbiomed.2007.08.003. [PMID: 17936191]
  • Marion Deon, Angela Sitta, Alethea G Barschak, Daniela M Coelho, Maiara Pigatto, Graziela O Schmitt, Laura B Jardim, Roberto Giugliani, Moacir Wajner, Carmen R Vargas. Induction of lipid peroxidation and decrease of antioxidant defenses in symptomatic and asymptomatic patients with X-linked adrenoleukodystrophy. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2007 Nov; 25(7):441-4. doi: 10.1016/j.ijdevneu.2007.08.008. [PMID: 17928186]
  • Fei Deng, Jun Chang, Jin-Sheng Zhang. New flavonoids and other constituents from Lespedeza cuneata. Journal of Asian natural products research. 2007 Sep; 9(6-8):655-8. doi: 10.1080/10286020600979894. [PMID: 17943561]
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