Pregnanediol (BioDeep_00000005845)
Main id: BioDeep_00000019532
human metabolite PANOMIX_OTCML-2023 Endogenous BioNovoGene_Lab2019
代谢物信息卡片
(1S,2S,5R,7R,10R,11S,14S,15S)-14-[(1S)-1-hydroxyethyl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-ol
化学式: C21H36O2 (320.2715)
中文名称: 孕甾二醇, 孕二醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C)O
InChI: InChI=1S/C21H36O2/c1-4-14-6-8-17-16-7-5-15-13-21(22,23)12-11-20(15,3)18(16)9-10-19(14,17)2/h14-18,22-23H,4-13H2,1-3H3/t14-,15?,16-,17-,18-,19+,20-/m0/s1
描述信息
Pregnanediol is an endogenous human testosterone metabolite. It can be detected in the urine of adults and newborns in variable concentrations. Pregnanediol is abnormally elevated in patients with cytochrome P450 (P450C17, steroid 17alpha-monooxygenase, EC 1.14.99.9) oxidoreductase deficiency (Antley-Bixler syndrome, PORD, OMIM: 201750). Antley-Bixler syndrome is a multiple congenital malformation syndrome with craniosynostosis, radiohumeral synostosis, femoral bowing, choanal atresia or stenosis, joint contractures, urogenital abnormalities, and often early death. An assay of urinary pregnanediol excretion provides an accurate indication of outcome in threatened miscarriage in 74 - 93\\\% percent of cases. Pregnanediol is one of the most important markers of pregnenolone administration, which can potentially be abused by athletes to maintain an equilibration of the steroidal environment after sex steroids administrations. Patients with recurrent vulvovaginal candidiasis have significantly lower levels of urinary pregnanediol (PMID: 126703, 16608896, 16906539, 1191599, 2905284, 15763596, 10360427, 11159778, 16687200). Pregnanediol excretion is low in women with suspected placental insufficiency and in women with uterine fibroma. Pregnanediol levels can change in endocrine disturbances such as hirsutism or Cushings syndrome, depending on the stage of the disease. Pregnanediol has been tried as a more reliable compound to measure in screening of urinary steroids when suspecting doping, due to its not significant isotopic fractionation that could lead to false positive results in anti-doping testing. 13C-Enrichment caused by a diet change might be a reason of concern in athletes that move around between places and might have a considerable change of diet between competitions. In contrast to the results obtained with the carbon isotopic ratio, the profiling of urinary testosterone/epitestosterone (T/E) ratios is found to be unaffected by a diet change (PMID: 16338181, 5172227, 13636945, 14440289).
Pregnanediol is an endogenous human testosterone metabolite. It can be detected in adults and newborns urine in variable concentrations. Pregnanediol is abnormally elevated in patients with cytochrome P450 (P450C17, steroid 17alpha-monooxygenase, EC 1.14.99.9) oxidoreductase deficiency (Antley-Bixler syndrome, PORD, OMIM 201750). Antley-Bixler syndrome is a multiple congenital malformation syndrome with craniosynostosis, radiohumeral synostosis, femoral bowing, choanal atresia or stenosis, joint contractures, urogenital abnormalities and, often, early death. An assay of urinary pregnanediol excretion provides an accurate indication of outcome in threatened abortion in 74 - 93\\\% per cent of cases. Pregnanediol is one of the most important markers of pregnenolone administration, which can potentially be abused by athletes to maintain an equilibration of the steroidal environment after sex steroids administrations. Patients with recurrent vulvovaginal candidiasis have significantly lower levels of urinary pregnanediol. (PMID: 126703, 16608896, 16906539, 1191599, 2905284, 15763596, 10360427, 11159778, 16687200) [HMDB]
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo[1].
同义名列表
18 个代谢物同义名
(1S,2S,5R,7R,10R,11S,14S,15S)-14-[(1S)-1-hydroxyethyl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-ol; 5β-Pregnane-3α,20α-diol; 3alpha,20alpha-Dihydroxy-5beta-pregnane; (3alpha,5beta,20S)-Pregnane-3,20-diol; 5beta-Pregnane-3alpha,20alpha-diol; Pregnane-3,20-diol, (3α,5β,20S); (3Α,5β,20S)-pregnane-3,20-diol; 3Α,20α-dihydroxy-5β-pregnane; 5Β-pregnane-3α,20α-diol; 5b-Pregnane-3a,20a-diol; 5beta-Pregnanediol; 5Β-pregnanediol; Pregnanediol; Pregnandiol; Diol; NSC 1612; NSC 47462; Pregnanediol
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:8387
- KEGG: C05484
- KEGGdrug: D00189
- PubChem: 219833
- HMDB: HMDB0004025
- Metlin: METLIN63335
- ChEMBL: CHEMBL269897
- Wikipedia: Pregnanediol
- MeSH: Pregnanediol
- foodb: FDB023280
- chemspider: 190585
- CAS: 80-92-2
- ChEBI: CHEBI:177534
- PubChem: 7844
- LipidMAPS: LMST02030202
- 3DMET: B05058
- NIKKAJI: J4.884D
- RefMet: Pregnanediol
- medchemexpress: HY-107850
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-963
- KNApSAcK: 177534
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- René Écochard, René Leiva, Thomas Bouchard, Hans Boehringer, Jean Iwaz, Ingrid Plotton. Descriptive analysis of the relationship between progesterone and basal body temperature across the menstrual cycle.
Steroids.
2022 02; 178(?):108964. doi:
10.1016/j.steroids.2022.108964. [PMID: 35065994] - David J Handelsman, Rama Nimmagadda, Reena Desai, Timothy D Handelsman, Belinda Whittle, Karolina Skorupskaite, Richard A Anderson. Direct measurement of pregnanediol 3-glucuronide (PDG) in dried urine spots by liquid chromatography-mass spectrometry to detect ovulation.
The Journal of steroid biochemistry and molecular biology.
2021 07; 211(?):105900. doi:
10.1016/j.jsbmb.2021.105900. [PMID: 33872762] - Robin Pla, Estelle Pujos-Guillot, Stéphanie Durand, Marion Brandolini-Bunlon, Delphine Centeno, David B Pyne, Jean-François Toussaint, Philippe Hellard. Non-targeted metabolomics analyses by mass spectrometry to explore metabolic stress after six training weeks in high level swimmers.
Journal of sports sciences.
2021 May; 39(9):969-978. doi:
10.1080/02640414.2020.1851933. [PMID: 33320058] - Daniel S McConnell, Sybil L Crawford, Nancy A Gee, Joyce T Bromberger, Rasa Kazlauskaite, Nancy E Avis, Carolyn J Crandall, Hadine Joffe, Howard M Kravitz, Carol A Derby, Ellen B Gold, Samar R El Khoudary, Sioban Harlow, Gail A Greendale, Bill L Lasley. Lowered progesterone metabolite excretion and a variable LH excretion pattern are associated with vasomotor symptoms but not negative mood in the early perimenopausal transition: Study of Women's Health Across the Nation.
Maturitas.
2021 May; 147(?):26-33. doi:
10.1016/j.maturitas.2021.03.003. [PMID: 33832644] - Loredana Iannella, Cristiana Colamonici, Davide Curcio, Francesco Botrè, Xavier de la Torre. Detecting the abuse of 19-norsteroids in doping controls: A new gas chromatography coupled to isotope ratio mass spectrometry method for the analysis of 19-norandrosterone and 19-noretiocholanolone.
Drug testing and analysis.
2021 Apr; 13(4):770-784. doi:
10.1002/dta.2985. [PMID: 33242373] - Keiko Mouri, Keiko Shimizu. Stability of chimpanzee (Pan troglodytes) urinary reproductive hormones during long-term preservation on filter paper.
Primates; journal of primatology.
2021 Mar; 62(2):289-296. doi:
10.1007/s10329-020-00864-9. [PMID: 32955646] - Stephen J Usala, María Elena Alliende, A Alexandre Trindade. The Fertility Indicator Equation Using Serum Progesterone and Urinary Pregnanediol-3-Glucuronide for Assessment of Ovulatory to Luteal Phase Transition.
Medicina (Kaunas, Lithuania).
2021 Feb; 57(2):. doi:
10.3390/medicina57020134. [PMID: 33546226] - Nichola Johnson, Sarah Maguire, Anna Morra, Pooja Middha Kapoor, Katarzyna Tomczyk, Michael E Jones, Minouk J Schoemaker, Clare Gilham, Manjeet K Bolla, Qin Wang, Joe Dennis, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Caroline Baynes, Laura E Beane Freeman, Matthias W Beckmann, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Bram Boeckx, Natalia V Bogdanova, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Daniele Campa, Federico Canzian, Jose E Castelao, Stephen J Chanock, Georgia Chenevix-Trench, Christine L Clarke, Don M Conroy, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Thilo Dörk, A Heather Eliassen, Christoph Engel, D Gareth Evans, Peter A Fasching, Jonine Figueroa, Giuseppe Floris, Henrik Flyger, Manuela Gago-Dominguez, Susan M Gapstur, Montserrat García-Closas, Mia M Gaudet, Graham G Giles, Mark S Goldberg, Anna González-Neira, Pascal Guénel, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Patricia A Harrington, Steven N Hart, Maartje J Hooning, John L Hopper, Anthony Howell, David J Hunter, Agnes Jager, Anna Jakubowska, Esther M John, Rudolf Kaaks, Renske Keeman, Elza Khusnutdinova, Cari M Kitahara, Veli-Matti Kosma, Stella Koutros, Peter Kraft, Vessela N Kristensen, Allison W Kurian, Diether Lambrechts, Loic Le Marchand, Martha Linet, Jan Lubiński, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, John W M Martens, Dimitrios Mavroudis, Rebecca Mayes, Alfons Meindl, Roger L Milne, Susan L Neuhausen, Heli Nevanlinna, William G Newman, Sune F Nielsen, Børge G Nordestgaard, Nadia Obi, Andrew F Olshan, Janet E Olson, Håkan Olsson, Ester Orban, Tjoung-Won Park-Simon, Paolo Peterlongo, Dijana Plaseska-Karanfilska, Katri Pylkäs, Gad Rennert, Hedy S Rennert, Kathryn J Ruddy, Emmanouil Saloustros, Dale P Sandler, Elinor J Sawyer, Rita K Schmutzler, Christopher Scott, Xiao-Ou Shu, Jacques Simard, Snezhana Smichkoska, Christof Sohn, Melissa C Southey, John J Spinelli, Jennifer Stone, Rulla M Tamimi, Jack A Taylor, Rob A E M Tollenaar, Ian Tomlinson, Melissa A Troester, Thérèse Truong, Celine M Vachon, Elke M van Veen, Sophia S Wang, Clarice R Weinberg, Camilla Wendt, Hans Wildiers, Robert Winqvist, Alicja Wolk, Wei Zheng, Argyrios Ziogas, Alison M Dunning, Paul D P Pharoah, Douglas F Easton, A Forbes Howie, Julian Peto, Isabel Dos-Santos-Silva, Anthony J Swerdlow, Jenny Chang-Claude, Marjanka K Schmidt, Nick Orr, Olivia Fletcher. CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers.
British journal of cancer.
2021 02; 124(4):842-854. doi:
10.1038/s41416-020-01185-w. [PMID: 33495599] - Rebecca L Taub, Simon Adriane Ellis, Genevieve Neal-Perry, Amalia S Magaret, Sarah W Prager, Elizabeth A Micks. The effect of testosterone on ovulatory function in transmasculine individuals.
American journal of obstetrics and gynecology.
2020 08; 223(2):229.e1-229.e8. doi:
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Journal of pharmaceutical and biomedical analysis.
2020 May; 184(?):113171. doi:
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The Journal of clinical endocrinology and metabolism.
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ACS nano.
2020 02; 14(2):2542-2552. doi:
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Menopause (New York, N.Y.).
2020 02; 27(2):127-133. doi:
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Epidemiology (Cambridge, Mass.).
2019 11; 30 Suppl 2(?):S76-S84. doi:
10.1097/ede.0000000000001079. [PMID: 31569156] - Rene Leiva, Marie McNamara-Kilian, Helen Niezgoda, René Ecochard, Thomas Bouchard. Pilot observational prospective cohort study on the use of a novel home-based urinary pregnanediol 3-glucuronide (PDG) test to confirm ovulation when used as adjunct to fertility awareness methods (FAMs) stage 1.
BMJ open.
2019 05; 9(5):e028496. doi:
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The American journal of clinical nutrition.
2019 02; 109(2):402-410. doi:
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Scientific reports.
2018 12; 8(1):17621. doi:
10.1038/s41598-018-36051-6. [PMID: 30514870] - Harriet Mary Gunn, Meng-Che Tsai, Alexandra McRae, Katharine S Steinbeck. Menstrual Patterns in the First Gynecological Year: A Systematic Review.
Journal of pediatric and adolescent gynecology.
2018 Dec; 31(6):557-565.e6. doi:
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Archives of disease in childhood.
2018 03; 103(3):235-239. doi:
10.1136/archdischild-2017-312968. [PMID: 28794095] - Jay L Lieberman, Mary Jane DE Souza, David A Wagstaff, Nancy I Williams. Menstrual Disruption with Exercise Is Not Linked to an Energy Availability Threshold.
Medicine and science in sports and exercise.
2018 03; 50(3):551-561. doi:
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Methods in molecular biology (Clifton, N.J.).
2018; 1735(?):505-515. doi:
10.1007/978-1-4939-7614-0_38. [PMID: 29380341] - Mariana Raño, Claudia R Valeggia, Martin M Kowalewski. Aged Black-and-Gold Howler Monkey Female (Alouatta caraya): A Sign of Reproductive Senescence?.
Folia primatologica; international journal of primatology.
2018; 89(2):101-110. doi:
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Medicine and science in sports and exercise.
2017 Nov; 49(11):2297-2304. doi:
10.1249/mss.0000000000001366. [PMID: 28692631] - Heather C M Allaway, Esther M John, Theresa H Keegan, Mary Jane De Souza. A pilot study on the utility of reduced urine collection frequency protocols for the assessment of reproductive hormones in adolescent girls.
Journal of pediatric endocrinology & metabolism : JPEM.
2017 Oct; 30(10):1083-1093. doi:
10.1515/jpem-2017-0050. [PMID: 28949930] - Nanette Santoro, Sybil L Crawford, Samar R El Khoudary, Amanda A Allshouse, Sherri-Ann Burnett-Bowie, Joel Finkelstein, Carol Derby, Karen Matthews, Howard M Kravitz, Sioban D Harlow, Gail A Greendale, Ellen B Gold, Rasa Kazlauskaite, Dan McConnell, Genevieve Neal-Perry, Jelena Pavlovic, John Randolph, Gerson Weiss, Hsiang-Yu Chen, Bill Lasley. Menstrual Cycle Hormone Changes in Women Traversing Menopause: Study of Women's Health Across the Nation.
The Journal of clinical endocrinology and metabolism.
2017 07; 102(7):2218-2229. doi:
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International journal of hygiene and environmental health.
2017 07; 220(5):799-809. doi:
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Environmental science & technology.
2017 Jun; 51(11):6498-6506. doi:
10.1021/acs.est.7b01231. [PMID: 28485925] - Taufiq Purna Nugraha, Michael Heistermann, Muhammad Agil, Bambang Purwantara, Iman Supriatna, Gholib Gholib, Carel P van Schaik, Tony Weingrill. Validation of a field-friendly extraction and storage method to monitor fecal steroid metabolites in wild orangutans.
Primates; journal of primatology.
2017 Apr; 58(2):285-294. doi:
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Journal of medical primatology.
2017 02; 46(1):3-8. doi:
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Journal of immunoassay & immunochemistry.
2017; 38(2):202-220. doi:
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Theriogenology.
2017 Jan; 87(?):179-186. doi:
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Fertility and sterility.
2016 Dec; 106(7):1793-1799.e2. doi:
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Neurology.
2016 Jul; 87(1):49-56. doi:
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BMC evolutionary biology.
2016 06; 16(1):140. doi:
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Human reproduction (Oxford, England).
2016 Feb; 31(2):445-53. doi:
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Theriogenology.
2016 Jan; 85(2):216-23. doi:
10.1016/j.theriogenology.2015.09.009. [PMID: 26454526] - David X Li, Sarah Romans, Mary Jane De Souza, Brian Murray, Gillian Einstein. Actigraphic and self-reported sleep quality in women: associations with ovarian hormones and mood.
Sleep medicine.
2015 Oct; 16(10):1217-24. doi:
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Theriogenology.
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Human reproduction (Oxford, England).
2015 Jun; 30(6):1460-72. doi:
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American journal of human biology : the official journal of the Human Biology Council.
2015 May; 27(3):358-71. doi:
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The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception.
2015; 20(6):438-50. doi:
10.3109/13625187.2015.1048331. [PMID: 26018113] - Chaofu Ke, Yan Hou, Haiyu Zhang, Kai Yang, Jingtao Wang, Bing Guo, Fan Zhang, Hailong Li, Xiaohua Zhou, Ying Li, Kang Li. Plasma Metabolic Profiles in Women are Menopause Dependent.
PloS one.
2015; 10(11):e0141743. doi:
10.1371/journal.pone.0141743. [PMID: 26580805] - Man Zhang, Jing Ju, Zhixu Wang, Jieshu Wu, Shanshan Geng, Jing Liu, Yuexin Yang. [Effects of daily consumption of milk powder on menstrual cycles and urine sex hormone concentrations of young women].
Wei sheng yan jiu = Journal of hygiene research.
2014 Sep; 43(5):754-8. doi:
NULL. [PMID: 25438529] - Sosthene Habumuremyi, Martha M Robbins, Katie A Fawcett, Tobias Deschner. Monitoring ovarian cycle activity via progestagens in urine and feces of female mountain gorillas: A comparison of EIA and LC-MS measurements.
American journal of primatology.
2014 Feb; 76(2):180-91. doi:
10.1002/ajp.22220. [PMID: 24123105] - Leonard F Blackwell, Pilar Vigil, Delwyn G Cooke, Catherine d'Arcangues, James B Brown. Monitoring of ovarian activity by daily measurement of urinary excretion rates of oestrone glucuronide and pregnanediol glucuronide using the Ovarian Monitor, Part III: variability of normal menstrual cycle profiles.
Human reproduction (Oxford, England).
2013 Dec; 28(12):3306-15. doi:
10.1093/humrep/det389. [PMID: 24170744] - R Ecochard, R Leiva, T Bouchard, H Boehringer, A Direito, A Mariani, R Fehring. Use of urinary pregnanediol 3-glucuronide to confirm ovulation.
Steroids.
2013 Oct; 78(10):1035-40. doi:
10.1016/j.steroids.2013.06.006. [PMID: 23831784] - D Martínez-Brito, M T Correa Vidal, X de la Torre, V García-Mir, O Ledea Lozano, M Granda Fraga. Reference ranges for the urinary steroid profile in a Latin-American population.
Drug testing and analysis.
2013 Aug; 5(8):619-26. doi:
10.1002/dta.1448. [PMID: 23339119] - MaLinda D Henry, Sarah J Hankerson, Jennifer M Siani, Jeffrey A French, James M Dietz. High rates of pregnancy loss by subordinates leads to high reproductive skew in wild golden lion tamarins (Leontopithecus rosalia).
Hormones and behavior.
2013 May; 63(5):675-83. doi:
10.1016/j.yhbeh.2013.02.009. [PMID: 23454002] - Nicole Reisch, Jan Idkowiak, Beverly A Hughes, Hannah E Ivison, Omar A Abdul-Rahman, Laura G Hendon, Ann Haskins Olney, Shelly Nielsen, Rachel Harrison, Edward M Blair, Vivek Dhir, Nils Krone, Cedric H L Shackleton, Wiebke Arlt. Prenatal diagnosis of congenital adrenal hyperplasia caused by P450 oxidoreductase deficiency.
The Journal of clinical endocrinology and metabolism.
2013 Mar; 98(3):E528-36. doi:
10.1210/jc.2012-3449. [PMID: 23365120] - Ana Direito, Sébastien Bailly, Aude Mariani, René Ecochard. Relationships between the luteinizing hormone surge and other characteristics of the menstrual cycle in normally ovulating women.
Fertility and sterility.
2013 Jan; 99(1):279-285.e3. doi:
10.1016/j.fertnstert.2012.08.047. [PMID: 22999798] - Ellaine Munton, Fong-Ha Liu, E John Murby, D Brynn Hibbert. Certification of steroid carbon isotope ratios in a freeze-dried human urine reference material.
Drug testing and analysis.
2012 Dec; 4(12):928-33. doi:
10.1002/dta.1366. [PMID: 22544546] - Aaryn C Mustoe, Heather A Jensen, Jeffrey A French. Describing ovarian cycles, pregnancy characteristics, and the use of contraception in female white-faced marmosets, Callithrix geoffroyi.
American journal of primatology.
2012 Nov; 74(11):1044-53. doi:
10.1002/ajp.22058. [PMID: 22865351] - Pieter Van Renterghem, Michael Polet, Lance Brooker, Wim Van Gansbeke, Peter Van Eenoo. Development of a GC/C/IRMS method--confirmation of a novel steroid profiling approach in doping control.
Steroids.
2012 Sep; 77(11):1050-60. doi:
10.1016/j.steroids.2012.05.009. [PMID: 22728892] - J Volkery, J Gottschalk, A Sobiraj, T Wittek, A Einspanier. Progesterone, pregnanediol-3-glucuronide, relaxin and oestrone sulphate concentrations in saliva, milk and urine of female alpacas (Vicugna pacos) and their application in pregnancy diagnosis.
The Veterinary record.
2012 Aug; 171(8):195. doi:
10.1136/vr.100393. [PMID: 22859412] - Ganesa Wegienka, Ewa Hasiec, Homer Boushey, Christine Cole Johnson, Ronald Strickler, Edward Zoratti, Suzanne Havstad. Studying forced expiratory volume at 1 second over menstrual segments in asthmatic and non-asthmatic women: assessing protocol feasibility.
BMC research notes.
2012 Jul; 5(?):261. doi:
10.1186/1756-0500-5-261. [PMID: 22642760] - Nichola Johnson, Kate Walker, Lorna J Gibson, Nick Orr, Elizabeth Folkerd, Ben Haynes, Claire Palles, Ben Coupland, Minouk Schoemaker, Michael Jones, Peter Broderick, Elinor Sawyer, Michael Kerin, Ian P Tomlinson, Marketa Zvelebil, Sarah Chilcott-Burns, Katarzyna Tomczyk, Gemma Simpson, Jill Williamson, Stephen G Hillier, Gillian Ross, Richard S Houlston, Anthony Swerdlow, Alan Ashworth, Mitch Dowsett, Julian Peto, Isabel Dos Santos Silva, Olivia Fletcher. CYP3A variation, premenopausal estrone levels, and breast cancer risk.
Journal of the National Cancer Institute.
2012 May; 104(9):657-69. doi:
10.1093/jnci/djs156. [PMID: 22472546] - Michael R Jarcho, Sally P Mendoza, Karen L Bales. Hormonal and experiential predictors of infant survivorship and maternal behavior in a monogamous primate (Callicebus cupreus).
American journal of primatology.
2012 May; 74(5):462-70. doi:
10.1002/ajp.22003. [PMID: 22318880] - Ildikó Bíró, Anita Bufa, Ferenc Wilhelm, Zoltán Mánfai, Ferenc Kilár, Péter Miklós Gocze. Urinary steroid profile in early pregnancy after in vitro fertilization.
Acta obstetricia et gynecologica Scandinavica.
2012 May; 91(5):625-9. doi:
10.1111/j.1600-0412.2012.01387.x. [PMID: 22375705] - Anna Ziomkiewicz, Szymon Wichary, Dorota Bochenek, Boguslaw Pawlowski, Grazyna Jasienska. Temperament and ovarian reproductive hormones in women: evidence from a study during the entire menstrual cycle.
Hormones and behavior.
2012 Apr; 61(4):535-40. doi:
10.1016/j.yhbeh.2012.01.017. [PMID: 22342576] - Leonard F Blackwell, Pilar Vigil, Barbara Gross, Catherine d'Arcangues, Delwyn G Cooke, James B Brown. Monitoring of ovarian activity by measurement of urinary excretion rates of estrone glucuronide and pregnanediol glucuronide using the Ovarian Monitor, Part II: reliability of home testing.
Human reproduction (Oxford, England).
2012 Feb; 27(2):550-7. doi:
10.1093/humrep/der409. [PMID: 22131389] - J L Scheid, R J Toombs, G Ducher, J C Gibbs, N I Williams, M J De Souza. Estrogen and peptide YY are associated with bone mineral density in premenopausal exercising women.
Bone.
2011 Aug; 49(2):194-201. doi:
10.1016/j.bone.2011.04.011. [PMID: 21549231] - Kathleen A O'Connor, Eleanor Brindle, Jane Shofer, Benjamin C Trumble, Jennifer D Aranda, Karen Rice, Marc Tatar. The effects of a long-term psychosocial stress on reproductive indicators in the baboon.
American journal of physical anthropology.
2011 Aug; 145(4):629-38. doi:
10.1002/ajpa.21538. [PMID: 21702002] - Ilze Vermaak, Josias H Hamman, Alvaro M Viljoen. Hoodia gordonii: an up-to-date review of a commercially important anti-obesity plant.
Planta medica.
2011 Jul; 77(11):1149-60. doi:
10.1055/s-0030-1250643. [PMID: 21259185] - Ellaine Munton, John Murby, D Brynn Hibbert, Rebeca Santamaria-Fernandez. Systematic comparison of δ13C measurements of testosterone and derivative steroids in a freeze-dried urine candidate reference material for sports drug testing by gas chromatography/combustion/isotope ratio mass spectrometry and uncertainty evaluation using four different metrological approaches.
Rapid communications in mass spectrometry : RCM.
2011 Jun; 25(11):1641-51. doi:
10.1002/rcm.4983. [PMID: 21594940] - Philippe Geoffroy, Blandine Ressault, Eric Marchioni, Michel Miesch. Synthesis of Hoodigogenin A, aglycone of natural appetite suppressant glycosteroids extracted from Hoodia gordonii.
Steroids.
2011 Jun; 76(7):702-8. doi:
10.1016/j.steroids.2011.03.014. [PMID: 21473873] - Thomas Piper, Christoph Schlug, Ute Mareck, Wilhelm Schänzer. Investigations on changes in ¹³C/¹²C ratios of endogenous urinary steroids after pregnenolone administration.
Drug testing and analysis.
2011 May; 3(5):283-90. doi:
10.1002/dta.281. [PMID: 21538944] - M Corr, M J De Souza, R J Toombs, N I Williams. Circulating leptin concentrations do not distinguish menstrual status in exercising women.
Human reproduction (Oxford, England).
2011 Mar; 26(3):685-94. doi:
10.1093/humrep/deq375. [PMID: 21227945] - Eduardo Fernandez-Duque, Kevin Burke, Kelsi Schoenrock, Christy K Wolovich, Claudia R Valeggia. Hormonal monitoring of reproductive status in monogamous wild female owl monkeys (Aotus azarai) of the Argentinean Chaco.
Folia primatologica; international journal of primatology.
2011; 82(3):143-53. doi:
10.1159/000333081. [PMID: 22116541] - Anne Marie Z Jukic, Clarice R Weinberg, Allen J Wilcox, Donna D Baird. Effects of early pregnancy loss on hormone levels in the subsequent menstrual cycle.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2010 Dec; 26(12):897-901. doi:
10.3109/09513590.2010.487601. [PMID: 20504096] - Janine Volkery, Thomas Wittek, Axel Sobiraj, Jutta Gottschalk, Almuth Einspanier. [Progesterone and pregnanediol-glucuronid concentrations in saliva, milk and urine of female alpacas and their application in pregnancy diagnosis].
Berliner und Munchener tierarztliche Wochenschrift.
2010 Nov; 123(11-12):500-5. doi:
. [PMID: 21141281] - N I Williams, J L Reed, H J Leidy, R S Legro, M J De Souza. Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 years.
Human reproduction (Oxford, England).
2010 Sep; 25(9):2328-39. doi:
10.1093/humrep/deq172. [PMID: 20605898] - Yoshiro Toma, Takumi Yanaihara. [Pregnanediol (P2), pregnanetriol (P3)].
Nihon rinsho. Japanese journal of clinical medicine.
2010 Jul; 68 Suppl 7(?):466-70. doi:
NULL. [PMID: 20960813] - Lubna Pal, Katie Zhang, Gohar Zeitlian, Nanette Santoro. Characterizing the reproductive hormone milieu in infertile women with diminished ovarian reserve.
Fertility and sterility.
2010 Mar; 93(4):1074-9. doi:
10.1016/j.fertnstert.2008.10.069. [PMID: 19100532] - M J De Souza, R J Toombs, J L Scheid, E O'Donnell, S L West, N I Williams. High prevalence of subtle and severe menstrual disturbances in exercising women: confirmation using daily hormone measures.
Human reproduction (Oxford, England).
2010 Feb; 25(2):491-503. doi:
10.1093/humrep/dep411. [PMID: 19945961] - Vamsi Lakshmi Madgula, Bharathi Avula, Rahul S Pawar, Yatin J Shukla, Ikhlas A Khan, Larry A Walker, Shabana I Khan. Characterization of in vitro pharmacokinetic properties of hoodigogenin A from Hoodia gordonii.
Planta medica.
2010 Jan; 76(1):62-9. doi:
10.1055/s-0029-1185949. [PMID: 19639535] - Jennifer J Henderson, John P Newnham, Karen Simmer, Peter E Hartmann. Effects of antenatal corticosteroids on urinary markers of the initiation of lactation in pregnant women.
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine.
2009 Dec; 4(4):201-6. doi:
10.1089/bfm.2008.0136. [PMID: 19772378] - Kathleen A O'Connor, Rebecca Ferrell, Eleanor Brindle, Benjamin Trumble, Jane Shofer, Darryl J Holman, Maxine Weinstein. Progesterone and ovulation across stages of the transition to menopause.
Menopause (New York, N.Y.).
2009 Nov; 16(6):1178-87. doi:
10.1097/gme.0b013e3181aa192d. [PMID: 19568209] - Thomas Piper, Phillip Riemann, Georg Opfermann, Ute Mareck, Hans Geyer, Graziela Vajiala, Ulrich Flenker, Wilhelm Schänzer. Determination of 13C/12C ratios of urinary epitestosterone and its main metabolites 5alpha- and 5beta-androstane-3alpha, 17alpha-diol.
Drug testing and analysis.
2009 Nov; 1(11-12):576-86. doi:
10.1002/dta.53. [PMID: 20355174] - Dana Rochester, Akas Jain, Alex J Polotsky, Hanah Polotsky, Karen Gibbs, Barbara Isaac, Gohar Zeitlian, Cheryl Hickmon, Sophia Feng, Nanette Santoro. Partial recovery of luteal function after bariatric surgery in obese women.
Fertility and sterility.
2009 Oct; 92(4):1410-1415. doi:
10.1016/j.fertnstert.2008.08.025. [PMID: 18829008] - Jennifer L Bedford, Jerilynn C Prior, Christine L Hitchcock, Susan I Barr. Detecting evidence of luteal activity by least-squares quantitative basal temperature analysis against urinary progesterone metabolites and the effect of wake-time variability.
European journal of obstetrics, gynecology, and reproductive biology.
2009 Sep; 146(1):76-80. doi:
10.1016/j.ejogrb.2009.05.001. [PMID: 19552997] - Natsuki Hama, Hideyasu Kanemitsu, Michiyo Tanikawa, Masami Shibaya, Kensuke Sakamoto, Yujiro Oyama, Tomas J Acosta, Osamu Ishikawa, Wang Pengyan, Kiyoshi Okuda. Development of an enzyme immunoassay for urinary pregnanediol-3-glucuronide in a female giant panda (Ailuropoda melanoleuca).
The Journal of veterinary medical science.
2009 Jul; 71(7):879-84. doi:
10.1292/jvms.71.879. [PMID: 19652473] - K Jewgenow, F Göritz, A Vargas, M Dehnhard. Seasonal profiles of ovarian activity in Iberian lynx (Lynx pardinus) based on urinary hormone metabolite analyses.
Reproduction in domestic animals = Zuchthygiene.
2009 Jul; 44 Suppl 2(?):92-7. doi:
10.1111/j.1439-0531.2009.01383.x. [PMID: 19754544] - Kelly Ishida, Juliany Cola Fernandes Rodrigues, Marcos Dornelas Ribeiro, Taíssa Vieira Machado Vila, Wanderley de Souza, Julio A Urbina, Celso Vataru Nakamura, Sonia Rozental. Growth inhibition and ultrastructural alterations induced by Delta24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organisms.
BMC microbiology.
2009 Apr; 9(?):74. doi:
10.1186/1471-2180-9-74. [PMID: 19379501] - Kathleen A O'Connor, Rebecca J Ferrell, Eleanor Brindle, Jane Shofer, Darryl J Holman, Rebecca C Miller, Deborah E Schechter, Burton Singer, Maxine Weinstein. Total and unopposed estrogen exposure across stages of the transition to menopause.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2009 Mar; 18(3):828-36. doi:
10.1158/1055-9965.epi-08-0996. [PMID: 19240232] - Sarah L West, Jennifer L Scheid, Mary Jane De Souza. The effect of exercise and estrogen on osteoprotegerin in premenopausal women.
Bone.
2009 Jan; 44(1):137-44. doi:
10.1016/j.bone.2008.09.008. [PMID: 18929691] - Kevin D Beck, Joselyn McLaughlin, Michael T Bergen, Tara P Cominski, Roberta L Moldow, Richard J Servatius. Facilitated acquisition of the classically conditioned eyeblink response in women taking oral contraceptives.
Behavioural pharmacology.
2008 Dec; 19(8):821-8. doi:
10.1097/fbp.0b013e32831c3b82. [PMID: 19020417] - Jason D Vescovi, Jennifer L Scheid, Rayisa Hontscharuk, Mary Jane De Souza. Cognitive dietary restraint: impact on bone, menstrual and metabolic status in young women.
Physiology & behavior.
2008 Sep; 95(1-2):48-55. doi:
10.1016/j.physbeh.2008.04.003. [PMID: 18508099] - Katherine Wander, Eleanor Brindle, Kathleen A O'Connor. C-reactive protein across the menstrual cycle.
American journal of physical anthropology.
2008 Jun; 136(2):138-46. doi:
10.1002/ajpa.20785. [PMID: 18257023] - N Santoro, S L Crawford, W L Lasley, J L Luborsky, K A Matthews, D McConnell, J F Randolph, E B Gold, G A Greendale, S G Korenman, L Powell, M F Sowers, G Weiss. Factors related to declining luteal function in women during the menopausal transition.
The Journal of clinical endocrinology and metabolism.
2008 May; 93(5):1711-21. doi:
10.1210/jc.2007-2165. [PMID: 18285413] - Jennifer E Mersereau, Michele L Evans, Dan H Moore, James H Liu, Michael A Thomas, Robert W Rebar, Ellen Pennington, Marcelle I Cedars. Luteal phase estrogen is decreased in regularly menstruating older women compared with a reference population of younger women.
Menopause (New York, N.Y.).
2008 May; 15(3):482-6. doi:
10.1097/gme.0b013e31815982cf. [PMID: 18202592] - Richard S Legro, Jaimey G Pauli, Allen R Kunselman, Juliana W Meadows, James S Kesner, Richard J Zaino, Laurence M Demers, Carol L Gnatuk, William C Dodson. Effects of continuous versus cyclical oral contraception: a randomized controlled trial.
The Journal of clinical endocrinology and metabolism.
2008 Feb; 93(2):420-9. doi:
10.1210/jc.2007-2287. [PMID: 18056769] - Robert W Shumaker, Serge A Wich, Lori Perkins. Reproductive life history traits of female orangutans (Pongo spp.).
Interdisciplinary topics in gerontology.
2008; 36(?):147-61. doi:
10.1159/000137705. [PMID: 18523377] - Ellen B Gold, Bill Lasley, Sybil L Crawford, Dan McConnell, Hadine Joffe, Gail A Greendale. Relation of daily urinary hormone patterns to vasomotor symptoms in a racially/ethnically diverse sample of midlife women: study of women's health across the nation.
Reproductive sciences (Thousand Oaks, Calif.).
2007 Dec; 14(8):786-97. doi:
10.1177/1933719107308613. [PMID: 18089597] - Anne Marie Zaura Jukic, Clarice R Weinberg, Donna D Baird, Allen J Wilcox. Lifestyle and reproductive factors associated with follicular phase length.
Journal of women's health (2002).
2007 Nov; 16(9):1340-7. doi:
10.1089/jwh.2007.0354. [PMID: 18001191] - Susanna J Park, Laura T Goldsmith, Joan H Skurnick, Andrea Wojtczuk, Gerson Weiss. Characteristics of the urinary luteinizing hormone surge in young ovulatory women.
Fertility and sterility.
2007 Sep; 88(3):684-90. doi:
10.1016/j.fertnstert.2007.01.045. [PMID: 17434509] - Martha J Lentz, Nancy Woods, Margaret Heitkemper, Ellen Mitchell, Richard Henker, Joan Shaver. Ovarian steroids and premenstrual symptoms: a comparison of group differences and intra-individual patterns.
Research in nursing & health.
2007 Jun; 30(3):238-49. doi:
10.1002/nur.20188. [PMID: 17514719] - Emma O'Donnell, Paula J Harvey, Jack M Goodman, Mary Jane De Souza. Long-term estrogen deficiency lowers regional blood flow, resting systolic blood pressure, and heart rate in exercising premenopausal women.
American journal of physiology. Endocrinology and metabolism.
2007 May; 292(5):E1401-9. doi:
10.1152/ajpendo.00547.2006. [PMID: 17227959] - Peter M Meyer, Scott L Zeger, Siobán D Harlow, Maryfran Sowers, Sybil Crawford, Judith L Luborsky, Imke Janssen, Daniel S McConnell, John F Randolph, Gerson Weiss. Characterizing daily urinary hormone profiles for women at midlife using functional data analysis.
American journal of epidemiology.
2007 Apr; 165(8):936-45. doi:
10.1093/aje/kwk090. [PMID: 17267418]
