Pentaporphyrin I (BioDeep_00000005719)
Secondary id: BioDeep_00001868729
human metabolite PANOMIX_OTCML-2023 Endogenous
代谢物信息卡片
化学式: C20H14N4 (310.1218)
中文名称: 卟啉
谱图信息:
最多检出来源 Homo sapiens(otcml) 44.28%
分子结构信息
SMILES: C1=CC2=CC3=CC=C(N3)C=C4C=CC(=N4)C=C5C=CC(=N5)C=C1N2
InChI: InChI=1S/C20H14N4/c1-2-14-10-16-5-6-18(23-16)12-20-8-7-19(24-20)11-17-4-3-15(22-17)9-13(1)21-14/h1-12,21-22H
描述信息
Pentaporphyrin I is a porphyrin intermediate detected in liver, kidney and erythrocytes (PubMed ID 8803328 ).
同义名列表
16 个代谢物同义名
21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3,5,7,9,11,13(22),14,16,18(21),19-undecaene; 2,10-Dimethoxy-6alpha-aporphine-1,9-diol; 2,10-Dimethoxy-6a-aporphine-1,9-diol; Protoporphyrin disodium; Pentaporphyrin I; 21H,23H-Porphine; delta-Isoboldine; 21H,23H-Porphin; (+)-Isoboldine; d-Isoboldine; Isoboldine; Porphyrin; Porphine; Prolmon; (S)-Isoboldine; Porphyrin
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:174230
- ChEBI: CHEBI:8337
- KEGG: C05113
- PubChem: 66868
- HMDB: HMDB0000839
- Metlin: METLIN66291
- foodb: FDB112165
- chemspider: 60231
- CAS: 3019-51-0
- CAS: 101-60-0
- PMhub: MS000018570
- PubChem: 7538
- 3DMET: B00751
- NIKKAJI: J9.336J
- RefMet: Porphyrin
- KEGG: C09541
- PubChem: 11732
- KNApSAcK: 5986
- KNApSAcK: 174230
- LOTUS: LTS0016385
- wikidata: Q421246
分类词条
相关代谢途径
BioCyc(0)
PlantCyc(0)
代谢反应
39 个相关的代谢反应过程信息。
Reactome(39)
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
CHOL + NPC2 ⟶ NPC2:CHOL
- ABC-family proteins mediated transport:
ATP + Cl- + H2O ⟶ ADP + Cl- + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
CHOL + phosphatidylcholines ⟶ 1-acyl LPC + CHEST
- ABC-family proteins mediated transport:
ATP + Cl- + H2O ⟶ ADP + Cl- + Pi
- Mitochondrial ABC transporters:
ATP + H2O + porphyrin ⟶ ADP + Pi + porphyrin
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
PKA tetramer + cAMP ⟶ PKA tetramer:4xcAMP
- ABC-family proteins mediated transport:
ATP + Cl- + H2O ⟶ ADP + Cl- + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
- Transport of small molecules:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi
- Mitochondrial ABC transporters:
ATP + H2O + heme ⟶ ADP + Pi + heme
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Vanda Andrade, M Luísa Mateus, M Camila Batoréu, Michael Aschner, A P Marreilha dos Santos. Changes in rat urinary porphyrin profiles predict the magnitude of the neurotoxic effects induced by a mixture of lead, arsenic and manganese.
Neurotoxicology.
2014 Dec; 45(?):168-77. doi:
10.1016/j.neuro.2014.10.009
. [PMID: 25451970] - Marcus C Durrant. A computational study of ligand binding affinities in iron(III) porphine and protoporphyrin IX complexes.
Dalton transactions (Cambridge, England : 2003).
2014 Jul; 43(25):9754-65. doi:
10.1039/c4dt01103a
. [PMID: 24846575] - James S Woods, Sarah E Armel, Denise I Fulton, Jason Allen, Kristine Wessels, P Lynne Simmonds, Doreen Granpeesheh, Elizabeth Mumper, J Jeffrey Bradstreet, Diana Echeverria, Nicholas J Heyer, James P K Rooney. Urinary porphyrin excretion in neurotypical and autistic children.
Environmental health perspectives.
2010 Oct; 118(10):1450-7. doi:
10.1289/ehp.0901713
. [PMID: 20576582]