Testololactone (BioDeep_00000005615)

   


代谢物信息卡片


10a,12a-Dimethyl-3,4,4a,5,6,9,10,10a,10b,11,12,12a-dodecahydro-2H-naphtho[2,1-f]chromene-2,8(4bh)-dione

化学式: C19H26O3 (302.1882)
中文名称:
谱图信息: 最多检出来源 Macaca mulatta(otcml) 6.75%

分子结构信息

SMILES: CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC(=O)O4)C
InChI: InChI=1S/C19H26O3/c1-18-9-7-13(20)11-12(18)3-4-14-15(18)8-10-19(2)16(14)5-6-17(21)22-19/h11,14-16H,3-10H2,1-2H3



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • R J Santen, D Leszczynski, N Tilson-Mallet, P D Feil, C Wright, A Manni, S J Santner. Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways. Annals of the New York Academy of Sciences. 1986; 464(?):126-37. doi: 10.1111/j.1749-6632.1986.tb16000.x. [PMID: 3524346]
  • R D'Agata, A Aliffi, G Maugeri, A Mongioi, E Vicari, S Gulizia, P Polosa. Hydrotestolactone lowers serum oestradiol and PRL levels in normal men: evidence of a role of oestradiol in prl secretion. Clinical endocrinology. 1982 Nov; 17(5):495-9. doi: 10.1111/j.1365-2265.1982.tb01617.x. [PMID: 7172459]
  • A Segaloff. delta 1-testololactone: clinical trials'. Cancer research. 1982 Aug; 42(8 Suppl):3387s-3388s. doi: NULL. [PMID: 7044522]
  • R D'Agata, E Vicari, A Aliffi, S Gulizia, G Palumbo. Direct evidence in men for a role of endogenous oestrogens on gonadotrophin release. Acta endocrinologica. 1981 Jun; 97(2):145-9. doi: 10.1530/acta.0.0970145. [PMID: 6785950]
  • R M Barone, I M Shamonki, P K Siiteri, H L Judd. Inhibition of peripheral aromatization of androstenedione to estrone in postmenopausal women with breast cancer using delta 1-testololactone. The Journal of clinical endocrinology and metabolism. 1979 Nov; 49(5):672-6. doi: 10.1210/jcem-49-5-672. [PMID: 489709]
  • M MARGOTTINI, G JACOBELLI, M CAU. [Behavior of serum lactic dehydrogenase (LDH) in disseminated breast cancer treated with delta-1-testololactone]. Gazzetta internazionale di medicina e chirurgia. 1962 Dec; 66(?):2890-9. doi: . [PMID: 13933033]
  • R P HOWARD, R H FURMAN. Metabolic and serum lipid effects of delta1-testololactone. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1962 Jun; 110(?):227-9. doi: 10.3181/00379727-110-27474. [PMID: 14449370]