L-Agaritine (BioDeep_00000004710)
Secondary id: BioDeep_00001868481
human metabolite
代谢物信息卡片
化学式: C12H17N3O4 (267.1219)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 61.26%
分子结构信息
SMILES: C1=CC(=CC=C1CO)NNC(=O)CCC(C(=O)O)N
InChI: InChI=1S/C12H17N3O4/c13-10(12(18)19)5-6-11(17)15-14-9-3-1-8(7-16)2-4-9/h1-4,10,14,16H,5-7,13H2,(H,15,17)(H,18,19)
描述信息
L-Agaritine is found in mushrooms. L-Agaritine is a constituent of some members of the family Agaricaceae, notably Agaricus bisporus (button mushroom).
Constituent of some members of the family Agaricaceae, notably Agaricus bisporus (button mushroom). L-Agaritine is found in mushrooms.
同义名列表
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:15336
- KEGG: C01550
- PubChem: 439517
- PubChem: 17688
- HMDB: HMDB0033758
- Metlin: METLIN65610
- Wikipedia: Agaritine
- foodb: FDB011894
- chemspider: 16720
- CAS: 2757-90-6
- PMhub: MS000017273
- PubChem: 4708
- KNApSAcK: C00001525
- NIKKAJI: J15.143B
- KNApSAcK: 15336
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
- 5341 - Agaricus bisporus:
- 3708 - Brassica napus: 10.3389/FNUT.2022.822033
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
- 9606 - Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Paul Urbain, Juan Valverde, Jette Jakobsen. Impact on Vitamin D2, Vitamin D4 and Agaritine in Agaricus bisporus Mushrooms after Artificial and Natural Solar UV Light Exposure.
Plant foods for human nutrition (Dordrecht, Netherlands).
2016 Sep; 71(3):314-21. doi:
10.1007/s11130-016-0562-5. [PMID: 27323764] - Kenji Sorimachi, Takaaki Nakamoto. Alternative medicine safety: Agaricus blazei and propolis.
Combinatorial chemistry & high throughput screening.
2011 Aug; 14(7):616-21. doi:
10.2174/138620711796367238. [PMID: 21599627] - Si-Yuan Pan, Si-Bao Chen, Hong-Guang Dong, Zhi-Ling Yu, Ji-Cui Dong, Zhi-Xian Long, Wang-Fun Fong, Yi-Fan Han, Kam-Ming Ko. New perspectives on chinese herbal medicine (zhong-yao) research and development.
Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):403709. doi:
10.1093/ecam/neq056. [PMID: 21785622] - Sanhong Yu, Veronika Weaver, Keith Martin, Margherita T Cantorna. The effects of whole mushrooms during inflammation.
BMC immunology.
2009 Feb; 10(?):12. doi:
10.1186/1471-2172-10-12. [PMID: 19232107] - Kazunari Kondo, Asako Watanabe, Hiroshi Akiyama, Tamio Maitani. The metabolisms of agaritine, a mushroom hydrazine in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Mar; 46(3):854-62. doi:
10.1016/j.fct.2007.10.022. [PMID: 18061328] - Jing-Fang Wang, Dong-Qing Wei, Kuo-Chen Chou. Drug candidates from traditional chinese medicines.
Current topics in medicinal chemistry.
2008; 8(18):1656-65. doi:
10.2174/156802608786786633. [PMID: 19075772] - Wei-Na Gao, Dong-Qing Wei, Yun Li, Hui Gao, Wei-Ren Xu, Ai-Xiu Li, Kuo-Chen Chou. Agaritine and its derivatives are potential inhibitors against HIV proteases.
Medicinal chemistry (Shariqah (United Arab Emirates)).
2007 May; 3(3):221-6. doi:
10.2174/157340607780620644. [PMID: 17504192] - Kazunari Kondo, Asako Watanabe, Yuko Iwanaga, Ikuro Abe, Hideya Tanaka, Megumi Hamano Nagaoka, Hiroshi Akiyama, Tamio Maitani. Analysis of agaritine in mushrooms and in agaritine-administered mice using liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 Apr; 834(1-2):55-61. doi:
10.1016/j.jchromb.2006.02.021. [PMID: 16527549] - K Walton, M M Coombs, L J King, R Walker, C Ioannides. Fate of the mushroom hydrazine agaritine in the rat and mouse.
Nutrition and cancer.
2000; 37(1):55-64. doi:
10.1207/s15327914nc3701_7. [PMID: 10965520] - S E Shephard, C Schlatter. Covalent binding of agaritine to DNA in vivo.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1998 Nov; 36(11):971-4. doi:
10.1016/s0278-6915(98)00076-3. [PMID: 9771560] - K Walton, M M Coombs, F S Catterall, R Walker, C Ioannides. Bioactivation of the mushroom hydrazine, agaritine, to intermediates that bind covalently to proteins and induce mutations in the Ames test.
Carcinogenesis.
1997 Aug; 18(8):1603-8. doi:
10.1093/carcin/18.8.1603. [PMID: 9276636] - S E Shephard, D Gunz, C Schlatter. Genotoxicity of agaritine in the lacI transgenic mouse mutation assay: evaluation of the health risk of mushroom consumption.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1995 Apr; 33(4):257-64. doi:
10.1016/0278-6915(94)00142-b. [PMID: 7737599] - C Papaparaskeva, C Ioannides, R Walker. Agaritine does not mediate the mutagenicity of the edible mushroom Agaricus bisporus.
Mutagenesis.
1991 May; 6(3):213-7. doi:
10.1093/mutage/6.3.213. [PMID: 1679191] - C Hashida, K Hayashi, L Jie, S Haga, M Sakurai, H Shimizu. [Quantities of agaritine in mushrooms (Agaricus bisporus) and the carcinogenicity of mushroom methanol extracts on the mouse bladder epithelium].
[Nihon koshu eisei zasshi] Japanese journal of public health.
1990 Jun; 37(6):400-5. doi:
. [PMID: 2132000] - A E Ross, D L Nagel, B Toth. Occurrence, stability and decomposition of beta-N [gamma-L(+)-glutamyl]-4-hydroxymethylphenylhydrazine (agaritine) from the mushroom Agaricus bisporus.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1982 Dec; 20(6):903-7. doi:
10.1016/s0015-6264(82)80226-5. [PMID: 6131022]
