5-O-(1-Carboxyvinyl)-3-phosphoshikimate (BioDeep_00000004639)

 

Secondary id: BioDeep_00001869434


代谢物信息卡片


5-(1-carboxyethenoxy)-4-hydroxy-3-phosphonooxycyclohexene-1-carboxylic acid

化学式: C10H13O10P (324.0246)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(lipidsearch) 30.92%

分子结构信息

SMILES: C=C(C(=O)O)OC1CC(=CC(C1O)OP(=O)(O)O)C(=O)O
InChI: InChI=1S/C10H13O10P/c1-4(9(12)13)19-6-2-5(10(14)15)3-7(8(6)11)20-21(16,17)18/h3,6-8,11H,1-2H2,(H,12,13)(H,14,15)(H2,16,17,18)/t6-,7-,8+/m1/s1



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

324 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(324)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 AXIN2, CA1, CA3, GRIN2B, HTR4, PRKX
Endosome membrane 1 HTR4
Endoplasmic reticulum membrane 4 DRD1, GRIN2A, GRIN2B, SFTPD
Nucleus 5 AXIN2, DRD1, GRM1, PRKX, REPIN1
cytosol 5 AXIN2, CA1, CA3, PRKCQ, REPIN1
dendrite 4 GRM1, HTR1A, HTR4, OPRM1
centrosome 1 AXIN2
nucleoplasm 2 PRKX, REPIN1
Cell membrane 8 DRD1, GRID1, GRIN2A, GRIN2B, GRM1, HTR1A, HTR4, OPRM1
Cell projection, axon 1 OPRM1
Multi-pass membrane protein 10 CACNA1I, DRD1, GRID1, GRIN2A, GRIN2B, GRM1, HTR1A, HTR4, KCNA3, OPRM1
Synapse 5 GRIN2A, HTR1A, HTR4, OPRM1, TAC1
cell surface 2 GRIN2A, GRIN2B
glutamatergic synapse 6 DRD1, GRID1, GRIN2A, GRM1, HTR4, KCNA3
Golgi apparatus 1 OPRM1
lysosomal membrane 1 AP5B1
neuronal cell body 1 TAC1
postsynapse 1 HTR4
presynaptic membrane 3 DRD1, GRIN2A, KCNA3
synaptic vesicle 1 GRIN2A
Cytoplasm, cytosol 1 REPIN1
Lysosome 2 GRIN2B, SFTPD
endosome 2 HTR4, OPRM1
plasma membrane 12 AXIN2, CACNA1I, DRD1, GRID1, GRIN2A, GRIN2B, GRM1, HTR1A, HTR4, KCNA3, OPRM1, PRKCQ
Membrane 6 CACNA1I, GRIN2A, GRIN2B, HTR4, KCNA3, OPRM1
axon 3 KCNA3, OPRM1, TAC1
extracellular exosome 3 CA1, GRID1, REG1A
endoplasmic reticulum 2 GRIN2A, OPRM1
extracellular space 3 REG1A, SFTPD, TAC1
perinuclear region of cytoplasm 1 KCNA3
Schaffer collateral - CA1 synapse 1 GRM1
postsynaptic density 2 GRIN2A, GRIN2B
extracellular region 2 SFTPD, TAC1
centriolar satellite 1 PRKCQ
ciliary membrane 1 DRD1
nuclear membrane 1 REPIN1
multivesicular body 1 SFTPD
dendritic spine 2 DRD1, GRIN2A
perikaryon 1 OPRM1
beta-catenin destruction complex 1 AXIN2
postsynaptic membrane 5 DRD1, GRID1, GRIN2A, GRIN2B, KCNA3
Membrane raft 1 KCNA3
Cytoplasm, cytoskeleton 1 GRIN2B
GABA-ergic synapse 2 DRD1, GRID1
collagen trimer 1 SFTPD
Cell projection, dendritic spine 2 DRD1, GRIN2A
Postsynaptic cell membrane 4 GRID1, GRIN2A, GRIN2B, GRM1
Late endosome 2 AP5B1, GRIN2B
neuron projection 3 GRIN2A, GRIN2B, OPRM1
cilium 1 DRD1
Chromosome 1 REPIN1
cytoskeleton 1 GRIN2B
non-motile cilium 1 DRD1
[Isoform 2]: Cell membrane 1 KCNA3
Cytoplasmic vesicle membrane 1 GRIN2A
Cell projection, dendrite 4 DRD1, GRIN2B, HTR1A, OPRM1
synaptic membrane 2 GRIN2A, GRIN2B
voltage-gated potassium channel complex 1 KCNA3
voltage-gated calcium channel complex 1 CACNA1I
endocytic vesicle 1 SFTPD
postsynaptic density membrane 4 GRID1, GRIN2A, GRIN2B, GRM1
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
clathrin-coated endocytic vesicle 1 SFTPD
calyx of Held 1 KCNA3
NMDA selective glutamate receptor complex 2 GRIN2A, GRIN2B
[Isoform 1]: Cell membrane 1 KCNA3
AP-5 adaptor complex 1 AP5B1
AP-type membrane coat adaptor complex 1 AP5B1
Cell projection, cilium membrane 1 DRD1
G protein-coupled receptor complex 1 DRD1
[Isoform 3]: Cytoplasm, perinuclear region 1 KCNA3
[Isoform 12]: Cytoplasm 1 OPRM1
G protein-coupled receptor dimeric complex 1 GRM1
G protein-coupled receptor homodimeric complex 1 GRM1


文献列表

  • Charlemagne Ajoc Lim, Prashant Jha, Vipan Kumar, Alan T Dyer. Effect of EPSPS gene copy number and glyphosate selection on fitness of glyphosate-resistant Bassia scoparia in the field. Scientific reports. 2021 08; 11(1):16083. doi: 10.1038/s41598-021-95517-2. [PMID: 34373526]
  • Yi Zhang, Licong Yi, Yongjun Lin, Lili Zhang, Zongze Shao, Ziduo Liu. Characterization and site-directed mutagenesis of a novel class II 5-enopyruvylshikimate-3-phosphate (EPSP) synthase from the deep-sea bacterium Alcanivorax sp. L27. Enzyme and microbial technology. 2014 Sep; 63(?):64-70. doi: 10.1016/j.enzmictec.2014.02.010. [PMID: 25039062]
  • Wei Wang, Hui Xia, Xiao Yang, Ting Xu, Hong Jiang Si, Xing Xing Cai, Feng Wang, Jun Su, Allison A Snow, Bao-Rong Lu. A novel 5-enolpyruvoylshikimate-3-phosphate (EPSP) synthase transgene for glyphosate resistance stimulates growth and fecundity in weedy rice (Oryza sativa) without herbicide. The New phytologist. 2014 Apr; 202(2):679-688. doi: 10.1111/nph.12428. [PMID: 23905647]
  • Jonathan Gressel, C Neal Stewart, L Val Giddings, Albert J Fischer, Jens Carl Streibig, Nilda R Burgos, Anthony Trewavas, Aldo Merotto, Christopher John Leaver, Klaus Ammann, Vivian Moses, Amy Lawton-Rauh. Overexpression of epsps transgene in weedy rice: insufficient evidence to support speculations about biosafety. The New phytologist. 2014 Apr; 202(2):360-362. doi: 10.1111/nph.12615. [PMID: 24645782]
  • P Macheroux, E Schönbrunn, D I Svergun, V V Volkov, M H Koch, S Bornemann, R N Thorneley. Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding. The Biochemical journal. 1998 Oct; 335 ( Pt 2)(?):319-27. doi: 10.1042/bj3350319. [PMID: 9761730]