L-2,3-Diaminopropionic acid (BioDeep_00000408260)

Main id: BioDeep_00000001214

 


代谢物信息卡片


L-2,3-Diaminopropionic acid

化学式: C3H8N2O2 (104.0586)
中文名称: L-2,3-二氨基丙酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(C(=O)O)N)N
InChI: InChI=1S/C3H8N2O2/c4-1-2(5)3(6)7/h2H,1,4-5H2,(H,6,7)/t2-/m0/s1

描述信息

COVID info from PDB, Protein Data Bank
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

2 个代谢物同义名

L-2,3-Diaminopropionic acid; L-2,3-Diaminopropanoate



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ALB, BLMH, CST2, CTH, DNAL1, GNAQ, RIDA, TUBB4B
Endosome membrane 1 BACE1
Nucleus 6 ALB, BLMH, EN1, GNAQ, RIDA, TUBB4B
cytosol 6 ALB, BLMH, CTH, RIDA, SST, TUBB4B
dendrite 2 BACE1, PNOC
trans-Golgi network 1 BACE1
centrosome 1 ALB
nucleoplasm 1 CD2
Cell membrane 6 BACE1, CD2, GNAQ, ITGAL, ITGAM, PDCD1
Lipid-anchor 1 GNAQ
Cell projection, axon 1 BACE1
Cytoplasmic granule 1 BLMH
Synapse 2 GNAQ, PNOC
cell surface 4 BACE1, CD2, ITGAL, ITGAM
glutamatergic synapse 1 GHRL
Golgi apparatus 4 ALB, BACE1, CD2, GNAQ
lysosomal membrane 1 GNAQ
neuronal cell body 3 BACE1, PNOC, SST
postsynapse 1 GHRL
synaptic vesicle 1 BACE1
Lysosome 1 BACE1
endosome 1 BACE1
plasma membrane 8 BACE1, CD2, CTH, GNAQ, ITGAL, ITGAM, PDCD1, PNOC
Membrane 6 BACE1, CTH, GNAQ, ITGAL, ITGAM, PDCD1
axon 3 BACE1, CCK, GHRL
extracellular exosome 8 ALB, BLMH, CTH, GNAQ, ITGAL, ITGAM, RIDA, TUBB4B
endoplasmic reticulum 2 ALB, BACE1
extracellular space 6 ALB, CCK, CST2, GHRL, ITGAM, SST
Schaffer collateral - CA1 synapse 1 GHRL
mitochondrion 1 RIDA
protein-containing complex 2 ALB, CD2
Single-pass type I membrane protein 5 BACE1, CD2, CTH, ITGAL, ITGAM
Secreted 7 ALB, CCK, CST2, GHRL, ITGAL, PNOC, SST
extracellular region 7 ALB, CCK, CD2, GHRL, PNOC, SST, TUBB4B
cytoplasmic side of plasma membrane 1 CD2
hippocampal mossy fiber to CA3 synapse 1 BACE1
mitochondrial matrix 1 RIDA
anchoring junction 1 ALB
photoreceptor outer segment 1 GNAQ
Nucleus membrane 1 GNAQ
nuclear membrane 1 GNAQ
external side of plasma membrane 4 CD2, ITGAL, ITGAM, PDCD1
Extracellular vesicle 1 TUBB4B
multivesicular body 1 BACE1
neuronal dense core vesicle lumen 1 GHRL
microtubule cytoskeleton 1 TUBB4B
Early endosome 1 BACE1
cell-cell junction 1 CD2
recycling endosome 1 BACE1
vesicle 1 CST2
Membrane raft 2 BACE1, ITGAM
Cytoplasm, cytoskeleton 1 TUBB4B
microtubule 2 DNAL1, TUBB4B
GABA-ergic synapse 1 SST
Peroxisome 1 RIDA
Late endosome 1 BACE1
ciliary basal body 1 ALB
chromatin 1 EN1
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
centriole 1 ALB
Golgi apparatus, trans-Golgi network 1 BACE1
spindle pole 1 ALB
blood microparticle 1 ALB
Cytoplasm, cytoskeleton, cilium axoneme 1 DNAL1
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
Endomembrane system 1 BACE1
axonemal microtubule 1 TUBB4B
heterotrimeric G-protein complex 1 GNAQ
Cytoplasmic vesicle membrane 1 BACE1
Cell projection, dendrite 1 BACE1
specific granule membrane 2 ITGAL, ITGAM
tertiary granule membrane 1 ITGAM
synaptic membrane 1 PNOC
plasma membrane raft 1 ITGAM
secretory granule lumen 1 GHRL
endoplasmic reticulum lumen 3 ALB, BACE1, GHRL
platelet alpha granule lumen 1 ALB
axon terminus 1 PNOC
azurophil granule lumen 1 TUBB4B
neuronal dense core vesicle 1 SST
integrin complex 2 ITGAL, ITGAM
integrin alphaL-beta2 complex 1 ITGAL
integrin alphaM-beta2 complex 1 ITGAM
ciliary transition fiber 1 ALB
Golgi-associated vesicle lumen 1 BACE1
outer dynein arm 1 DNAL1


文献列表

  • Rym Boulfekhar, Leanne Ohlund, Kathrina Mae Kumaresan, Meriem Megoura, Thomas D Warkentin, Pompilia Ispas-Szabo, Lekha Sleno, Mircea Alexandru Mateescu. Diamine Oxidase as a Therapeutic Enzyme: Study of Germination from Vegetal Sources and Investigation of the Presence of β-N-Oxalyl-L-α,β-diaminopropionic Acid (β-ODAP) Using LC-MS/MS. International journal of molecular sciences. 2023 Feb; 24(5):. doi: 10.3390/ijms24054625. [PMID: 36902055]
  • Surendra Barpete, Priyanka Gupta, Debjyoti Sen Gupta, Jitendra Kumar, Arpan Bhowmik, Shiv Kumar. Neurotoxin (N-Oxalyl-L-α,β-Diamino Propionic Acid) Content in Different Plant Parts of Grass Pea (Lathyrus sativus L.) Spanning Seedling to Maturity Stage: Does It Increase over Time?. Molecules (Basel, Switzerland). 2022 Jun; 27(12):. doi: 10.3390/molecules27123683. [PMID: 35744809]
  • Jie Li, Pengcheng Qiu, Siwang Wang, Junsheng Wu, Qiaoyan He, Kaifeng Li, Lu Xu. β-N-Oxalyl-L-α,β-diaminopropionic acid from Panax notoginseng plays a major role in the treatment of type 2 diabetic nephropathy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019 Jun; 114(?):108801. doi: 10.1016/j.biopha.2019.108801. [PMID: 30928803]
  • Kecheng Quan, Guofeng Li, Lei Tao, Qian Xie, Qipeng Yuan, Xing Wang. Diaminopropionic Acid Reinforced Graphene Sponge and Its Use for Hemostasis. ACS applied materials & interfaces. 2016 Mar; 8(12):7666-73. doi: 10.1021/acsami.5b12715. [PMID: 26978481]
  • Soohyun Um, So Hyun Park, Jihye Kim, Hyen Joo Park, Keebeom Ko, Hea-Son Bang, Sang Kook Lee, Jongheon Shin, Dong-Chan Oh. Coprisamides A and B, new branched cyclic peptides from a gut bacterium of the dung beetle Copris tripartitus. Organic letters. 2015 Mar; 17(5):1272-5. doi: 10.1021/acs.orglett.5b00249. [PMID: 25686280]
  • Fabio Gresta, Concetta Rocco, Grazia M Lombardo, Giovanni Avola, Giuseppe Ruberto. Agronomic characterization and α- and β-ODAP determination through the adoption of new analytical strategies (HPLC-ELSD and NMR) of ten sicilian accessions of grass pea. Journal of agricultural and food chemistry. 2014 Mar; 62(11):2436-42. doi: 10.1021/jf500149n. [PMID: 24559213]
  • Urska Bukovnik, Monica Sala-Rabanal, Simonne Francis, Shawnalea J Frazier, Bruce D Schultz, Colin G Nichols, John M Tomich. Effect of diaminopropionic acid (Dap) on the biophysical properties of a modified synthetic channel-forming peptide. Molecular pharmaceutics. 2013 Oct; 10(10):3959-66. doi: 10.1021/mp4002377. [PMID: 24010543]
  • Andrea Kragler, Georg Höfner, Klaus T Wanner. Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4. European journal of pharmacology. 2005 Sep; 519(1-2):43-7. doi: 10.1016/j.ejphar.2005.06.053. [PMID: 16111674]
  • F Baechtold, J A Scott, M Markert, S Mehta, D G McCormack, F Anglada, D Galaud, M Vaglio, B Waeber, F Feihl. Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture?. Shock (Augusta, Ga.). 2001 Aug; 16(2):137-42. doi: 10.1097/00024382-200116020-00009. [PMID: 11508866]
  • J E Van Nuwenborg, D Stöckl, L M Thienpont. Practical aspects of suppressed ion chromatography for cations in human serum. Journal of chromatography. A. 1997 May; 770(1-2):137-41. doi: 10.1016/s0021-9673(96)01030-8. [PMID: 9203361]
  • C B Xue, J Roderick, S Jackson, M Rafalski, A Rockwell, S Mousa, R E Olson, W F DeGrado. Design, synthesis, and in vitro activities of benzamide-core glycoprotein IIb/IIIa antagonists: 2,3-diaminopropionic acid derivatives as surrogates of aspartic acid. Bioorganic & medicinal chemistry. 1997 Apr; 5(4):693-705. doi: 10.1016/s0968-0896(97)00013-8. [PMID: 9158868]
  • A N Mayeno, E A Belongia, F Lin, S K Lundy, G J Gleich. 3-(Phenylamino)alanine, a novel aniline-derived amino acid associated with the eosinophilia-myalgia syndrome: a link to the toxic oil syndrome?. Mayo Clinic proceedings. 1992 Dec; 67(12):1134-9. doi: 10.1016/s0025-6196(12)61142-2. [PMID: 1469924]
  • J P Kaltenbach, F A Carone, C E Ganote. Compounds protective against renal tubular necrosis induced by D-serine and D-2,3-diaminopropionic acid in the rat. Experimental and molecular pathology. 1982 Oct; 37(2):225-34. doi: 10.1016/0014-4800(82)90038-7. [PMID: 6814950]
  • R M Kater, N Carulli, F L Iber. Differences in the rate of ethanol metabolism in recently drinking alcoholic and nondrinking subjects. The American journal of clinical nutrition. 1969 Dec; 22(12):1608-17. doi: 10.1093/ajcn/22.12.1608. [PMID: 5362487]