2,5-Dihydroxybenzaldehyde (BioDeep_00000406077)

Main id: BioDeep_00000001204

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


2,5-Dihydroxybenzaldehyde

化学式: C7H6O3 (138.0317)
中文名称: 2,5-二羟基苯甲醛
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1O)C=O)O
InChI: InChI=1S/C7H6O3/c8-4-5-3-6(9)1-2-7(5)10/h1-4,9-10H

描述信息

A dihydroxybenzaldehyde carrying hydroxy groups at positions 2 and 5.
2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus strains with a MIC50 of 500 mg/L[1][2].

同义名列表

3 个代谢物同义名

2,5-Dihydroxybenzaldehyde; Gentisaldehyde; 2,5-Dihydroxybenzaldehyde



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

36 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • H W Chen, W Zhou, Y Liao, S C Hu, T L Chen, Z C Song. Analysis of metabolic profiles of generalized aggressive periodontitis. Journal of periodontal research. 2018 Oct; 53(5):894-901. doi: 10.1111/jre.12579. [PMID: 29974463]
  • Md Iqbal Alam, Mohammed A Alam, Ozair Alam, Amit Nargotra, Subhash Chandra Taneja, Surrinder Koul. Molecular modeling and snake venom phospholipase A2 inhibition by phenolic compounds: Structure-activity relationship. European journal of medicinal chemistry. 2016 May; 114(?):209-19. doi: 10.1016/j.ejmech.2016.03.008. [PMID: 26986086]
  • Stella W Nowotarska, Krzysztof J Nowotarski, Mendel Friedman, Chen Situ. Effect of structure on the interactions between five natural antimicrobial compounds and phospholipids of bacterial cell membrane on model monolayers. Molecules (Basel, Switzerland). 2014 Jun; 19(6):7497-515. doi: 10.3390/molecules19067497. [PMID: 24914896]
  • Vanisree Mulabagal, Ruby L Alexander-Lindo, David L Dewitt, Muraleedharan G Nair. Health-Beneficial Phenolic Aldehyde in Antigonon leptopus Tea. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):601249. doi: 10.1093/ecam/nep041. [PMID: 19454555]
  • Chung-Mu Yu, Miao-Ju Yen, Lin-Chi Chen. A bioanode based on MWCNT/protein-assisted co-immobilization of glucose oxidase and 2,5-dihydroxybenzaldehyde for glucose fuel cells. Biosensors & bioelectronics. 2010 Jul; 25(11):2515-21. doi: 10.1016/j.bios.2010.04.016. [PMID: 20472420]
  • Chao-Bin Xue, Li Zhang, Wan-Chun Luo, Xian-Ye Xie, Lin Jiang, Ting Xiao. 3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors. Bioorganic & medicinal chemistry. 2007 Mar; 15(5):2006-15. doi: 10.1016/j.bmc.2006.12.038. [PMID: 17258462]
  • Dorothee Spies-Martin, Olaf Sommerburg, Claus-Dieter Langhans, Michael Leichsenring. Measurement of 4-hydroxynonenal in small volume blood plasma samples: modification of a gas chromatographic-mass spectrometric method for clinical settings. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Jul; 774(2):231-9. doi: 10.1016/s1570-0232(02)00242-8. [PMID: 12076693]
  • S Rauli, M D Puppo, F Magni, M G Kienle. Validation of malondialdehyde and 4-hydroxy-2-trans-nonenal measurement in plasma by NICI-GC-MS. Journal of biochemistry. 1998 May; 123(5):918-23. doi: 10.1093/oxfordjournals.jbchem.a022025. [PMID: 9562626]
  • A L Sheffer, D T Fearon, K F Austen. Methyltestosterone therapy in hereditary angioedema. Annals of internal medicine. 1977 Mar; 86(3):306-8. doi: 10.7326/0003-4819-86-3-306. [PMID: 320930]